Bowditch effect: Difference between revisions
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An autoregulation method with which myocardial contractility increases with an increase in heart rate. | An autoregulation method with which myocardial contractility increases with an increase in heart rate. | ||
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One of the explanations is the inability of the [[Na+/K+-ATPase]] to keep up with influx of sodium at higher heart rates. This results in an accumulation of calcium in the myocardial cell via the [[sodium calcium exchanger]]. | One of the explanations is the inability of the [[Na+/K+-ATPase]] to keep up with influx of sodium at higher heart rates. This results in an accumulation of calcium in the myocardial cell via the [[sodium calcium exchanger]]. | ||
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Latest revision as of 23:06, 8 August 2012
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An autoregulation method with which myocardial contractility increases with an increase in heart rate.
One of the explanations is the inability of the Na+/K+-ATPase to keep up with influx of sodium at higher heart rates. This results in an accumulation of calcium in the myocardial cell via the sodium calcium exchanger.