Nigericin: Difference between revisions
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'''Nigericin''' is an [[antibiotic]] derived from ''[[Streptomyces]] hygroscopicus''. Commercially it is obtained as a byproduct, or contaminant, at the fermentation of [[Geldanamycin]]. It is also called | '''Nigericin''' is an [[antibiotic]] derived from ''[[Streptomyces]] hygroscopicus''. Commercially it is obtained as a byproduct, or contaminant, at the fermentation of [[Geldanamycin]]. It is also called | ||
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Latest revision as of 14:19, 20 August 2012
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WikiDoc Resources for Nigericin |
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Most recent articles on Nigericin |
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Evidence Based Medicine |
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Clinical Trials |
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Ongoing Trials on Nigericin at Clinical Trials.gov Clinical Trials on Nigericin at Google
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US National Guidelines Clearinghouse on Nigericin
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Commentary |
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Definitions |
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Patient Resources / Community |
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Patient resources on Nigericin Discussion groups on Nigericin Directions to Hospitals Treating Nigericin Risk calculators and risk factors for Nigericin
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Healthcare Provider Resources |
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Causes & Risk Factors for Nigericin |
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Continuing Medical Education (CME) |
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Experimental / Informatics |
Nigericin is an antibiotic derived from Streptomyces hygroscopicus. Commercially it is obtained as a byproduct, or contaminant, at the fermentation of Geldanamycin. It is also called
Polyetherin A, Azalomycin M, Helixin C, Antibiotic K178, Antibiotic X-464.
Nigericin acts as an H+, K+, Pb++ ionophore. It most commonly is an antiporter of H+ and K+.
In the past Nigericin was used as an antibiotic active against gram positive bacteria. It inhibits the Golgi functions. Nigericin exhibits anti-HIV activity.
Properties
- CAS number: 28643-80-3
- Merck index: 12, 6633
- Molecular weight: 747
- Formula C40H67O11Na
The properties are copied from a manufacturer's Nigericin product page]
External references