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A '''case series''' (also known as a '''clinical series''') is a medical research study that tracks patients with a known exposure or examines their medical records for exposure and outcome. A '''case series''' can be [[retrospective]] or [[prospective]] and usually involves a smaller number of patients than more [[statistical power|powerful]] [[case-control|case-control studies]] or [[randomized controlled trial|randomized controlled trials]]. | |||
A '''case series''' (also known as a '''clinical series''') is a medical research study that tracks patients with a known exposure given similar treatment<ref name="urlDefinition of case series - NCI Dictionary of Cancer Terms">{{cite web |url=http://www.cancer.gov/Templates/db_alpha.aspx?CdrID=44006 |title=Definition of case series - NCI Dictionary of Cancer Terms |format= |work= |accessdate=}}</ref> or examines their medical records for exposure and outcome. | |||
A '''case series''' can be [[retrospective]] or [[prospective]] and usually involves a smaller number of patients than more [[statistical power|powerful]] [[case-control|case-control studies]] or [[randomized controlled trial|randomized controlled trials]]. | |||
A case series is a type of [[observational study]]. Case series may be ''consecutive''<ref name="urlDefinition of consecutive case series - NCI Dictionary of Cancer Terms">{{cite web |url=http://www.cancer.gov/Templates/db_alpha.aspx?CdrID=285747 |title=Definition of consecutive case series - NCI Dictionary of Cancer Terms |format= |work= |accessdate=}}</ref> or ''non-consecutive'',<ref name="urlDefinition of nonconsecutive case series - NCI Dictionary of Cancer Terms">{{cite web |url=http://www.cancer.gov/Templates/db_alpha.aspx?CdrID=44575 |title=Definition of nonconsecutive case series - NCI Dictionary of Cancer Terms |format= |work= |accessdate=}}</ref> depending on whether all cases presenting to the reporting authors over a period of time were included, or only a selection. | |||
Case series may be [[confounding|confounded]] by [[selection bias]], which limits statements on the [[causality]] of correlations observed. | |||
==See also== | |||
*[[Case report]] | |||
==References== | |||
{{reflist|2}} | |||
{{Medical research studies}} | {{Medical research studies}} | ||
[[Category:Evaluation methods]] | |||
[[Category:Clinical trials]] | |||
[[es:Estudio de serie de casos]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 15:22, 4 September 2012
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A case series (also known as a clinical series) is a medical research study that tracks patients with a known exposure given similar treatment[1] or examines their medical records for exposure and outcome.
A case series can be retrospective or prospective and usually involves a smaller number of patients than more powerful case-control studies or randomized controlled trials.
A case series is a type of observational study. Case series may be consecutive[2] or non-consecutive,[3] depending on whether all cases presenting to the reporting authors over a period of time were included, or only a selection.
Case series may be confounded by selection bias, which limits statements on the causality of correlations observed.