Anti-smooth muscle antibody: Difference between revisions
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==Overview== | |||
'''Anti-smooth muscle antibodies''' are [[antibody|antibodies]] ([[immunoglobulin]]s) formed against [[smooth muscle]]. These antibodies are typically associated with [[autoimmune hepatitis]].<ref name="Dawkins">{{cite journal | last=Dawkins | first=RL | coauthors=Joske RA | title=Immunoglobulin deposition in liver of patients with active chronic hepatitis and antibody against smooth muscle | journal=British Medical Journal | volume=2 | issue=5867 | pages=643–645 | month=June | year=1973 | pmid=4577016 | doi=10.1136/bmj.2.5867.643 | pmc=1589647 }}</ref><ref name="Gershwin2007">{{cite book|author=M. Eric Gershwin|title=Liver immunology: principles and practice|url=http://books.google.com/books?id=ahddq6n6by4C&pg=PA265|accessdate=26 October 2010|year=2007|publisher=Humana Press|isbn=978-1-58829-818-8|pages=265–}}</ref> | |||
These antibodies can be directed against [[actin]], [[troponin]], and [[tropomyosin]].<ref name="Pollard2006">{{cite book|author=Kenneth Michael Pollard|title=Autoantibodies and autoimmunity: molecular mechanisms in health and disease|url=http://books.google.com/books?id=lRsyQV1fiv4C&pg=PA293|accessdate=26 October 2010|year=2006|publisher=Wiley-VCH|isbn=978-3-527-31141-5|pages=293–}}</ref> | |||
== References == | |||
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[[Category:Autoantibodies]] | |||
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Latest revision as of 16:13, 6 September 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Anti-smooth muscle antibodies are antibodies (immunoglobulins) formed against smooth muscle. These antibodies are typically associated with autoimmune hepatitis.[1][2]
These antibodies can be directed against actin, troponin, and tropomyosin.[3]
References
- ↑ Dawkins, RL (1973). "Immunoglobulin deposition in liver of patients with active chronic hepatitis and antibody against smooth muscle". British Medical Journal. 2 (5867): 643–645. doi:10.1136/bmj.2.5867.643. PMC 1589647. PMID 4577016. Unknown parameter
|coauthors=ignored (help); Unknown parameter|month=ignored (help) - ↑ M. Eric Gershwin (2007). Liver immunology: principles and practice. Humana Press. pp. 265–. ISBN 978-1-58829-818-8. Retrieved 26 October 2010.
- ↑ Kenneth Michael Pollard (2006). Autoantibodies and autoimmunity: molecular mechanisms in health and disease. Wiley-VCH. pp. 293–. ISBN 978-3-527-31141-5. Retrieved 26 October 2010.