Rh disease medical therapy: Difference between revisions
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Created page with "__NOTOC__ {{Rh disease}} {{CMG}} ==Overview== ==References== {{reflist|2}} {{WH}} {{WS}} Category:Blood disorders Category:Hematology Category:Obstetrics [[Categ..." |
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==Overview== | ==Overview== | ||
==Medical Therapy== | |||
'''Antenatal''' | |||
*Ultrasound - to detect and monitor [[hydrops fetalis]] | |||
*Quantitative analysis of maternal anti-RhD antibodies - an increasing level is a sign of fetal Rh disease<ref>http://www.ncbi.nlm.nih.gov/pubmed?term=14105934</ref> | |||
*Intrauterine blood transfusion | |||
**Intraperitoneal transfusion - blood transfused into fetal abdomen | |||
**Intravascular transfusion - blood transfused into fetal [[umbilical vein]] - This is more modern and more effective than intraperitoneal transfusion. A sample of fetal blood can be taken from the umbilical vein prior to the transfusion. | |||
*Early delivery (usually after about 36 wks gestation) | |||
'''Postnatal''' | |||
*Phototherapy for [[neonatal jaundice]] in mild disease | |||
*[[Exchange transfusion]] if the neonate has moderate or severe disease (the blood for transfusion must be less than a week old, Rh negative, ABO compatible with both the fetus and the mother, and be cross matched against the mothers serum) | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Latest revision as of 15:00, 21 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Antenatal
- Ultrasound - to detect and monitor hydrops fetalis
- Quantitative analysis of maternal anti-RhD antibodies - an increasing level is a sign of fetal Rh disease[1]
- Intrauterine blood transfusion
- Intraperitoneal transfusion - blood transfused into fetal abdomen
- Intravascular transfusion - blood transfused into fetal umbilical vein - This is more modern and more effective than intraperitoneal transfusion. A sample of fetal blood can be taken from the umbilical vein prior to the transfusion.
- Early delivery (usually after about 36 wks gestation)
Postnatal
- Phototherapy for neonatal jaundice in mild disease
- Exchange transfusion if the neonate has moderate or severe disease (the blood for transfusion must be less than a week old, Rh negative, ABO compatible with both the fetus and the mother, and be cross matched against the mothers serum)