Obesity hypoventilation syndrome overview: Difference between revisions
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The obesity hypoventilation syndrome consists of the combination of [[obesity]] ([[body mass index]] above 30 kg/m<sup>2</sup>), falling [[oxygen]] levels in blood ([[Hypoxia (medical)|hypoxia]]) during sleep and increasing [[carbon dioxide]] levels ([[hypercapnia]]); this is the result of [[hypoventilation]] (excessively slow or shallow breathing) during sleep.<ref name=Sleep1999>{{cite journal |author=Anonymous |title=Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force |journal=Sleep |volume=22 |issue=5 |pages=667–89 |year=1999 |pmid=10450601 |doi=}}</ref> [[Sleep apnea|Obstructive sleep apnea]] is often but not necessarily present.<ref name="Olson2005">{{cite journal |author=Olson AL, Zwillich C |title=The obesity hypoventilation syndrome |journal=Am. J. Med. |volume=118 |issue=9 |pages=948–56 |year=2005 |pmid=16164877 |doi=10.1016/j.amjmed.2005.03.042|url= http://www.amjmed.com/article/PIIS0002934305003372/fulltext}}</ref> | The obesity hypoventilation syndrome consists of the combination of [[obesity]] ([[body mass index]] above 30 kg/m<sup>2</sup>), falling [[oxygen]] levels in blood ([[Hypoxia (medical)|hypoxia]]) during sleep and increasing [[carbon dioxide]] levels ([[hypercapnia]]); this is the result of [[hypoventilation]] (excessively slow or shallow breathing) during sleep.<ref name=Sleep1999>{{cite journal |author=Anonymous |title=Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force |journal=Sleep |volume=22 |issue=5 |pages=667–89 |year=1999 |pmid=10450601 |doi=}}</ref> [[Sleep apnea|Obstructive sleep apnea]] is often but not necessarily present.<ref name="Olson2005">{{cite journal |author=Olson AL, Zwillich C |title=The obesity hypoventilation syndrome |journal=Am. J. Med. |volume=118 |issue=9 |pages=948–56 |year=2005 |pmid=16164877 |doi=10.1016/j.amjmed.2005.03.042|url= http://www.amjmed.com/article/PIIS0002934305003372/fulltext}}</ref> | ||
It may cause [[dyspnea]] (difficulty breathing), poor sleep with daytime tiredness, [[edema|leg swelling]] and various other symptoms. The main treatments are [[Weight loss#Intentional weight loss|weight loss]] and nocturnal ventilation (with [[Positive airway pressure|CPAP]] or related methods). The exact pathophysiologic mechanism remains unknown.<ref name="Olson2005"/>==References== | It may cause [[dyspnea]] (difficulty breathing), poor sleep with daytime tiredness, [[edema|leg swelling]] and various other symptoms. The main treatments are [[Weight loss#Intentional weight loss|weight loss]] and nocturnal ventilation (with [[Positive airway pressure|CPAP]] or related methods). The exact pathophysiologic mechanism remains unknown.<ref name="Olson2005"/> | ||
==References== | |||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
Latest revision as of 13:36, 24 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The obesity hypoventilation syndrome consists of the combination of obesity (body mass index above 30 kg/m2), falling oxygen levels in blood (hypoxia) during sleep and increasing carbon dioxide levels (hypercapnia); this is the result of hypoventilation (excessively slow or shallow breathing) during sleep.[1] Obstructive sleep apnea is often but not necessarily present.[2]
It may cause dyspnea (difficulty breathing), poor sleep with daytime tiredness, leg swelling and various other symptoms. The main treatments are weight loss and nocturnal ventilation (with CPAP or related methods). The exact pathophysiologic mechanism remains unknown.[2]
References
- ↑ Anonymous (1999). "Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force". Sleep. 22 (5): 667–89. PMID 10450601.
- ↑ 2.0 2.1 Olson AL, Zwillich C (2005). "The obesity hypoventilation syndrome". Am. J. Med. 118 (9): 948–56. doi:10.1016/j.amjmed.2005.03.042. PMID 16164877.