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'''For patient information, click [[Jaundice (patient information)|here]]'''
'''For patient information, click [[Jaundice (patient information)|here]]'''


{{SI}}
{{Ureteropelvic junction obstruction}}
{{CMG}}
{{CMG}} {{AE}} [[User:zorkun|Cafer Zorkun]] M.D., PhD.


{{AE}} [[User:zorkun|Cafer Zorkun]] M.D., PhD.
{{SK}} UPJ obstruction; UP junction obstruction; obstruction of the ureteropelvic junction
==Overview==


'''Ureteropelvic junction obstruction''' (UPJO) is defined as functional or anatomic obstruction to urine flow from the renal pelvis into the ureter at their anatomic junction. <ref>Leo P. Lawler, Thomas W. Jarret, Frank M. Corl, and Elliot K. Fishman. [http://radiographics.rsnajnls.org/cgi/content/abstract/25/1/121 Adult Ureteropelvic Junction Obstruction: Insights with Three-dimensional Multi–Detector Row CT.] RadioGraphics 2005 25: 121-134.</ref>
==[[Ureteropelvic junction obstruction overview|Overview]]==


If left untreated, results in symptoms, renal damage, or both.
==[[Ureteropelvic junction obstruction historical perspective|Historical Perspective]]==


UPJO generally implies a congenital partial proximal ureteric obstruction detected in utero or in later life.
==[[Ureteropelvic junction obstruction classification|Classification]]==


*The ureterovascular tangle is a term that embraces the renal pelvis, ureter, and adjacent vessels (both arterial and venous), all of which alone or in combination have been implicated as potential causes of UPJO.
==[[Ureteropelvic junction obstruction pathophysiology|Pathophysiology]]==
**The Vasculature: In the context of UPJO, "crossing vessels" are those renal arteries or veins found in the region of the ureteric transition point.
**The Ureter: The normal ureter inserts at the inferior aspect of the renal pelvis at an oblique angle and with gradual taper. It has been noted that in the setting of UPJO, the ureter tends to have a more cephalad or acute insertion.


*Therapy: Characteristic symptoms with morphologic evidence of UPJO may indicate a need for therapy.
==[[Ureteropelvic junction obstruction causes|Causes]]==
*Such symptoms include intermittent pain after drinking large volumes of fluid or fluids with a diuretic effect.
*Asymptomatic UPJO may be treated if there is evidence of asymmetric function or deterioration in renal function or [[hydronephrosis]].


==Diagnosis==
==[[Ureteropelvic junction obstruction differential diagnosis|Differentiating Ureteropelvic junction obstruction from other Diseases]]==


[[Hydronephrosis]] to the level of the ureteropelvic junction.
==[[Ureteropelvic junction obstruction epidemiology and demographics|Epidemiology and Demographics]]==
 
===Diagnostic Findings===


[http://www.radswiki.net Images courtesy of RadsWiki]
==[[Ureteropelvic junction obstruction risk factors|Risk Factors]]==


<gallery>
==[[Ureteropelvic junction obstruction natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
Image:UPJ-Obstruction-001.jpg|CT image demonstrates left UPJ obstruction
Image:UPJ-Obstruction-002.jpg|CT image demonstrates left UPJ obstruction
Image:UPJ-Obstruction-003.jpg|CT image demonstrates left UPJ obstruction
Image:UPJ-Obstruction-004.jpg|CT image demonstrates left UPJ obstruction
</gallery>


==References==
==Diagnosis==
{{Reflist|2}}
[[Ureteropelvic junction obstruction history and symptoms|History and Symptoms]] | [[Ureteropelvic junction obstruction physical examination|Physical Examination]] | [[Ureteropelvic junction obstruction laboratory findings|Laboratory Findings]] | [[Ureteropelvic junction obstruction x ray|X Ray]] | [[Ureteropelvic junction obstruction CT|CT]] | [[Ureteropelvic junction obstruction MRI|MRI]] | [[Ureteropelvic junction obstruction echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Ureteropelvic junction obstruction other imaging findings|Other Imaging Findings]] | [[Ureteropelvic junction obstruction other diagnostic studies|Other Diagnostic Studies]]
==Treatment==
[[Ureteropelvic junction obstruction medical therapy|Medical Therapy]] | [[Ureteropelvic junction obstruction surgery|Surgery]] | [[Ureteropelvic junction obstruction cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Ureteropelvic junction obstruction future or investigational therapies|Future or Investigational Therapies]]
==Case Studies==
[[Ureteropelvic junction obstruction case study one|Case #1]]


==External Links==
==External Links==

Latest revision as of 13:09, 28 September 2012

Ureteropelvic junction obstruction

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Cafer Zorkun M.D., PhD.

Synonyms and keywords: UPJ obstruction; UP junction obstruction; obstruction of the ureteropelvic junction

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Ureteropelvic junction obstruction from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

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