Cyanotic heart defect laboratory findings: Difference between revisions
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{{Cyanotic heart defect}} | {{Cyanotic heart defect}} | ||
{{CMG}}; '''Associate Editor-in-Chief:''' [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu] | {{CMG}}; '''Associate Editor-in-Chief:''' [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu]; {{KD}} | ||
==Overview== | ==Overview== | ||
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* [[High uric acid levels]] ([[hyperuricemia]]) | * [[High uric acid levels]] ([[hyperuricemia]]) | ||
* [[Proteinuria]] | * [[Proteinuria]] | ||
*Checking oxygen levels in the blood using an arterial blood gas test or by checking it through the skin with a [[pulse oximeter]] | |||
*[[Complete blood count]] (CBC) | |||
* Hyperoxia test: A '''hyperoxia test''' is a test that is performed--usually on an infant-- to determine whether the patient's [[cyanosis]] is due to lung disease or a problem with blood circulation.<ref name=Nadas>{{cite book|last=Fyler|first=edited by John F. Keane, James E. Lock, Donald C.|title=Nadas' pediatric cardiology|year=2006|publisher=Saunders [u.a.]|location=Philadelphia [u.a.]|isbn=978-1-4160-2390-6|edition=2nd ed.|url=http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-2390-6..50016-7--cesec22&isbn=978-1-4160-2390-6&sid=1223957161&uniqId=288314811-3#4-u1.0-B978-1-4160-2390-6..50016-7--cesec31}}</ref><sup></sup><ref name=pedsed>{{cite web|url=http://www.pediatriceducation.org/2006/01/23/ |title=When Do Cyanotic Congenital Heart Diseases Present? |publisher=Pediatric Education |date=2006-01-23 |accessdate=2011-10-26}}</ref> It is performed by measuring the [[arterial blood gases]] of the patient while he breathes room air, then re-measuring the blood gases after the patient has breathed 100% oxygen for 10 minutes.<ref name=Nadas></ref><sup></sup><ref name=PedsOnCall>{{cite web|author=Dr. Ira Shah |url=http://www.pediatriconcall.com/fordoctor/Conference_abstracts/Blue_baby.asp |title=How To Manage Blue Baby Maha Neocon 2005 pediatric oncall |publisher=Pediatriconcall.com |date=2006-02-15 |accessdate=2011-10-26}}</ref> If the cause of the cyanosis is due to poor oxygen saturation by the lungs, allowing the patient to breath 100% O2 will augment the lungs' ability to saturate the blood with oxygen, and the [[partial pressure]] of oxygen in the arterial blood will rise (usually above 150 [[mmHg]]<ref name=PedsOnCall />). However, if the lungs are healthy and already fully saturating the blood that is delivered to them, then supplemental oxygen will have no effect, and the partial pressure of oxygen will usually remain below 100mmHg.<ref name=PedsOnCall/> In this case, the cyanosis is most likely due to blood that moves from the systemic veins to the systemic arteries via a [[right-to-left shunt]] without ever going through the lungs.<ref name=Nadas/><sup></sup> | |||
==References== | ==References== | ||
Latest revision as of 22:01, 18 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-in-Chief: Keri Shafer, M.D. [2]; Kalsang Dolma, M.B.B.S.[3]
Overview
Laboratory Findings
- Erythrocytosis
- The platelet count is usually low
- Iron deficiency anemia
- Reduced RBC survival time
- Increased blood viscosity due to rigid RBCs.
- Reduces RBCs oxygen carrying capacity
- Hb > 20gm/dl
- Increased prothrombin time
- Increased aPTT
- Decreased coagulation factors
- Decreased platelets, abnormal platelet function
- High uric acid levels (hyperuricemia)
- Proteinuria
- Checking oxygen levels in the blood using an arterial blood gas test or by checking it through the skin with a pulse oximeter
- Complete blood count (CBC)
- Hyperoxia test: A hyperoxia test is a test that is performed--usually on an infant-- to determine whether the patient's cyanosis is due to lung disease or a problem with blood circulation.[1][2] It is performed by measuring the arterial blood gases of the patient while he breathes room air, then re-measuring the blood gases after the patient has breathed 100% oxygen for 10 minutes.[1][3] If the cause of the cyanosis is due to poor oxygen saturation by the lungs, allowing the patient to breath 100% O2 will augment the lungs' ability to saturate the blood with oxygen, and the partial pressure of oxygen in the arterial blood will rise (usually above 150 mmHg[3]). However, if the lungs are healthy and already fully saturating the blood that is delivered to them, then supplemental oxygen will have no effect, and the partial pressure of oxygen will usually remain below 100mmHg.[3] In this case, the cyanosis is most likely due to blood that moves from the systemic veins to the systemic arteries via a right-to-left shunt without ever going through the lungs.[1]
References
- ↑ 1.0 1.1 1.2 Fyler, edited by John F. Keane, James E. Lock, Donald C. (2006). Nadas' pediatric cardiology (2nd ed. ed.). Philadelphia [u.a.]: Saunders [u.a.] ISBN 978-1-4160-2390-6.
- ↑ "When Do Cyanotic Congenital Heart Diseases Present?". Pediatric Education. 2006-01-23. Retrieved 2011-10-26.
- ↑ 3.0 3.1 3.2 Dr. Ira Shah (2006-02-15). "How To Manage Blue Baby Maha Neocon 2005 pediatric oncall". Pediatriconcall.com. Retrieved 2011-10-26.