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{{Mitral valve prolapse}}
{{Mitral valve prolapse}}
{{CMG}}
{{CMG}}; {{FK}}
== Overview ==
 
== Causes ==
==Overview==
* Acquired
[[Mitral valve prolapse]] (MVP) is a [[valvular heart disease]] that is considered to be mainly hereditary. [[Myxomatous degeneration]] of the [[mitral valve]] is a common cause of MVP. Other less common causes of MVP include [[connective tissue diseases]] such as [[Marfan's syndrome]], [[Ehlers Danlos syndrome]] and [[osteogenesis imperfecta]], as well as damage to the [[mitral valve]] secondary to [[infarction]], [[rheumatic heart disease]], [[hypertrophic cardiomyopathy]] and [[trauma]].
* Congenital
 
* [[Marfan's Syndrome]]
==Causes==
* Myxomatous generation of the mitral valve
===Common Causes===
* Papillary muscle infarction
* [[Marfan's syndrome]]
* Papillary muscle trauma
* [[Myxomatous degeneration]] of the mitral valve
* [[Papillary muscle]] infarction
* [[Papillary muscle]] trauma
 
===Causes by Organ System===
{|style="width:82%; height:100px" border="1"
 
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
 
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |[[Myxomatous degeneration|myxomatous]] of the [[mitral valve]], [[myocardial infarction]], severe [[mitral annular calcification]], damaged [[chordae tendineae]], [[rheumatic heart disease]], [[papillary muscle dysfunction]], [[hypertrophic cardiomyopathy]], forme fruste Barlow disease, [[Ebstein's anomaly ]], [[cardiomegaly]], [[bacterial endocarditis]], [[congenital heart disease]]
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Chemical/Poisoning'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Dental'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Dermatologic'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Drug Side Effect'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Ear Nose Throat'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Endocrine'''
 
|bgcolor="Beige"|[[Graves disease]]
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Environmental'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Gastroenterologic'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Genetic'''
 
|bgcolor="Beige"|[[Turner Syndrome]], [[spastic ataxia]], Charlevoix-Saguenay type, [[osteogenesis imperfecta]], [[Mitral valve prolapse, familial, X linked|X-linked familial mitral valve prolapse]], [[Mitral valve prolapse, familial, autosomal dominant|autosomal dominant familial mitral valve prolapse]], [[MASS phenotype]], [[Marfan syndrome]], Marfan-like syndrome  Boileau type, Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Hematologic'''
 
|bgcolor="Beige"|[[Von Willebrand disease]], [[sickle cell disease ]]
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Iatrogenic'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Infectious Disease'''
 
|bgcolor="Beige"|[[Infective endocarditis]], [[acute rheumatic fever]]
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Musculoskeletal/Orthopedic'''
 
|bgcolor="Beige"|Dermato-cardio-skeletal syndrome Borrone type
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Neurologic'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Nutritional/Metabolic'''
 
|bgcolor="Beige"|[[Scurvy]]
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Obstetric/Gynecologic'''
 
|bgcolor="Beige"|[[Pregnancy]]
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Oncologic'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Ophthalmologic'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Overdose/Toxicity'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Psychiatric'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Pulmonary'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Renal/Electrolyte'''
 
|bgcolor="Beige"|[[Polycystic kidney disease]]
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Rheumatology/Immunology/Allergy'''
 
|bgcolor="Beige"|[[SLE]], [[pseudoxanthoma elasticum]], [[polyarteritis nodosa]], [[connective tissue disease]], [[mixed connective tissue disease]], [[Ehlers-Danlos syndrome]] type I, [[Ehlers-Danlos syndrome]] type II, [[Ehlers-Danlos syndrome]] Type V
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Sexual'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Trauma'''
 
|bgcolor="Beige"|[[Trauma ]] to [[mitral valve]]
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Urologic'''
 
|bgcolor="Beige"| No underlying causes
 
|-
 
|-bgcolor="LightSteelBlue"
 
| '''Miscellaneous'''
 
|bgcolor="Beige"|Stickler Syndrome, [[Leopard syndrome]], [[idiopathic]], fibroelastic deficiency, Dahlberg syndrome, [[Beals syndrome]]
 
|-
 
|}
 
===Causes in Alphabetical Order===
 
{{col-begin|width=84%}}
 
{{col-break|width=33%}}
 
*[[Acute myocardial ischemia]]
 
*[[Acute rheumatic fever]]
 
*Adult [[polycystic kidney disease]]
 
*Associated with [[congenital heart disease]]
 
*Associated with [[connective tissue disease]]
 
*[[Bacterial endocarditis]]
 
*[[Beals syndrome]]
 
*[[Cardiomegaly]]
 
*Chordal rupture
 
*Dahlberg syndrome
 
*Dermato-cardio-skeletal syndrome Borrone type
 
*[[Ebstein's anomaly ]]
 
*[[Ehlers-Danlos syndrome]] Type I
 
*[[Ehlers-Danlos syndrome]] type II
 
*[[Ehlers-Danlos syndrome]] type V
 
*Fibroelastic deficiency
 
*Forme fruste Barlow disease
 
{{col-break|width=33%}}
 
*Furlong-Kurczynski-Hennessy syndrome
 
*[[Graves disease]]
 
*Hunter-Mcdonald syndrome
 
*[[Hypertrophic cardiomyopathy]]
 
*[[Idiopathic]]
 
*[[Infective Endocarditis]]
 
*[[Leopard syndrome]]
 
*[[Marfan syndrome]]
 
*Marfan-like syndrome, Boileau type
 
*[[MASS phenotype]]
 
*[[Mitral valve prolapse, familial, autosomal dominant]]
 
*[[Mitral valve prolapse, familial, X linked]]
 
*[[Mixed connective tissue disease]]
 
*[[Myxomatous degeneration|Myxomatous]] [[mitral valve prolapse ]]
 
*[[Osteogenesis imperfecta]]
 
*[[Papillary muscle dysfunction]]
 
*[[Pectus excavatum]]
 
{{col-break|width=33%}}
 
*[[Polyarteritis nodosa]]
 
*[[Polycystic kidney disease]]
 
*[[Pregnancy]]
 
*[[Pseudoxanthoma elasticum]]
 
*[[Rheumatic heart disease]]
 
*Ruptured chordae
 
*[[Scoliosis]]
 
*[[Scurvy]]
 
*Severe [[mitral annular calcification ]]
 
*[[Sickle cell disease ]]
 
*[[SLE]]
 
*[[Spastic ataxia]] Charlevoix-Saguenay type
 
*[[ST elevation myocardial infarction]]
 
*Stickler syndrome
 
*[[Trauma ]]
 
*[[Turner Syndrome]]
 
*[[Von Willebrand disease]]
 
{{col-end}}


==References==
==References==
{{reflist|2}}
{{reflist|2}}


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Latest revision as of 13:43, 16 July 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Farman Khan, MD, MRCP [2]

Overview

Mitral valve prolapse (MVP) is a valvular heart disease that is considered to be mainly hereditary. Myxomatous degeneration of the mitral valve is a common cause of MVP. Other less common causes of MVP include connective tissue diseases such as Marfan's syndrome, Ehlers Danlos syndrome and osteogenesis imperfecta, as well as damage to the mitral valve secondary to infarction, rheumatic heart disease, hypertrophic cardiomyopathy and trauma.

Causes

Common Causes

Causes by Organ System

Cardiovascular myxomatous of the mitral valve, myocardial infarction, severe mitral annular calcification, damaged chordae tendineae, rheumatic heart disease, papillary muscle dysfunction, hypertrophic cardiomyopathy, forme fruste Barlow disease, Ebstein's anomaly , cardiomegaly, bacterial endocarditis, congenital heart disease
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine Graves disease
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic Turner Syndrome, spastic ataxia, Charlevoix-Saguenay type, osteogenesis imperfecta, X-linked familial mitral valve prolapse, autosomal dominant familial mitral valve prolapse, MASS phenotype, Marfan syndrome, Marfan-like syndrome Boileau type, Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome
Hematologic Von Willebrand disease, sickle cell disease
Iatrogenic No underlying causes
Infectious Disease Infective endocarditis, acute rheumatic fever
Musculoskeletal/Orthopedic Dermato-cardio-skeletal syndrome Borrone type
Neurologic No underlying causes
Nutritional/Metabolic Scurvy
Obstetric/Gynecologic Pregnancy
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte Polycystic kidney disease
Rheumatology/Immunology/Allergy SLE, pseudoxanthoma elasticum, polyarteritis nodosa, connective tissue disease, mixed connective tissue disease, Ehlers-Danlos syndrome type I, Ehlers-Danlos syndrome type II, Ehlers-Danlos syndrome Type V
Sexual No underlying causes
Trauma Trauma to mitral valve
Urologic No underlying causes
Miscellaneous Stickler Syndrome, Leopard syndrome, idiopathic, fibroelastic deficiency, Dahlberg syndrome, Beals syndrome

Causes in Alphabetical Order

References

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Template:WS