Mitral valve prolapse causes: Difference between revisions

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__NOTOC__
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{{Mitral valve prolapse}}
{{Mitral valve prolapse}}
{{CMG}}; {{FK}}


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==Overview==
[[Mitral valve prolapse]] (MVP) is a [[valvular heart disease]] that is considered to be mainly hereditary. [[Myxomatous degeneration]] of the [[mitral valve]] is a common cause of MVP. Other less common causes of MVP include [[connective tissue diseases]] such as [[Marfan's syndrome]], [[Ehlers Danlos syndrome]] and [[osteogenesis imperfecta]], as well as damage to the [[mitral valve]] secondary to [[infarction]], [[rheumatic heart disease]], [[hypertrophic cardiomyopathy]] and [[trauma]].


{{CMG}}
==Causes==
== Overview ==
===Common Causes===
===Common Causes ===
* [[Marfan's syndrome]]
* Acquired
* [[Myxomatous degeneration]] of the mitral valve
* Congenital
* [[Papillary muscle]] infarction
* [[Marfan's Syndrome]]
* [[Papillary muscle]] trauma
* Myxomatous generation of the mitral valve
* Papillary muscle infarction
* Papillary muscle trauma


===Causes by Organ System===
===Causes by Organ System===
{|style="width:82%; height:100px" border="1"
{|style="width:82%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
 
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |[[Myxomatous degeneration|myxomatous]] of the [[mitral valve]], [[myocardial infarction]], severe [[mitral annular calcification]], damaged [[chordae tendineae]], [[rheumatic heart disease]], [[papillary muscle dysfunction]], [[hypertrophic cardiomyopathy]], forme fruste Barlow disease, [[Ebstein's anomaly ]], [[cardiomegaly]], [[bacterial endocarditis]], [[congenital heart disease]]
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Chemical/Poisoning'''
| '''Chemical/Poisoning'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Dental'''
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[Graves disease]]
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Environmental'''
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[Turner Syndrome]], [[spastic ataxia]], Charlevoix-Saguenay type, [[osteogenesis imperfecta]], [[Mitral valve prolapse, familial, X linked|X-linked familial mitral valve prolapse]], [[Mitral valve prolapse, familial, autosomal dominant|autosomal dominant familial mitral valve prolapse]], [[MASS phenotype]], [[Marfan syndrome]], Marfan-like syndrome  Boileau type, Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[Von Willebrand disease]], [[sickle cell disease ]]
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[Infective endocarditis]], [[acute rheumatic fever]]
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|Dermato-cardio-skeletal syndrome Borrone type
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[Scurvy]]
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[Pregnancy]]
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
| '''Overdose/Toxicity'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| '''Renal/Electrolyte'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[Polycystic kidney disease]]
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[SLE]], [[pseudoxanthoma elasticum]], [[polyarteritis nodosa]], [[connective tissue disease]], [[mixed connective tissue disease]], [[Ehlers-Danlos syndrome]] type I, [[Ehlers-Danlos syndrome]] type II, [[Ehlers-Danlos syndrome]] Type V
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Sexual'''
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|[[Trauma ]] to [[mitral valve]]
 
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Urologic'''
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
 
|bgcolor="Beige"|Stickler Syndrome, [[Leopard syndrome]], [[idiopathic]], fibroelastic deficiency, Dahlberg syndrome, [[Beals syndrome]]
 
|-
|-
|}
|}


===Causes in Alphabetical Order===
===Causes in Alphabetical Order===
{{Multicol}}
 
{{col-begin|width=84%}}
 
{{col-break|width=33%}}
 
*[[Acute myocardial ischemia]]
*[[Acute myocardial ischemia]]
*[[Acute rheumatic fever]]
*[[Acute rheumatic fever]]
*Adult [[polycystic kidney disease]]
*Adult [[polycystic kidney disease]]
*Associated with [[congenital heart disease]]
*Associated with [[congenital heart disease]]
*Associated with [[connective tissue disease]]
*Associated with [[connective tissue disease]]
*[[Bacterial Endocarditis]]
 
*[[Bacterial endocarditis]]
 
*[[Beals syndrome]]
*[[Beals syndrome]]
*[[Cardiomegaly]]
*[[Cardiomegaly]]
*Chordal rupture
*Chordal rupture
*Dahlberg syndrome
*Dahlberg syndrome
*Dermato-cardio-skeletal syndrome Borrone type
*Dermato-cardio-skeletal syndrome Borrone type
*[[Ebstein's anomaly ]]
*[[Ebstein's anomaly ]]
*[[Ehlers-Danlos syndrome]] Type I
*[[Ehlers-Danlos syndrome]] Type I
*[[Ehlers-Danlos syndrome]] type II
*[[Ehlers-Danlos syndrome]] type II
*[[Ehlers-Danlos syndrome]] type V
*[[Ehlers-Danlos syndrome]] type V
*Fibroelastic deficiency
*Fibroelastic deficiency
*Forme fruste [[Barlow disease]]
 
*Forme fruste Barlow disease
 
{{col-break|width=33%}}
 
*Furlong-Kurczynski-Hennessy syndrome
*Furlong-Kurczynski-Hennessy syndrome
*[[Graves disease]]
*[[Graves disease]]
*Hunter-Mcdonald syndrome
*Hunter-Mcdonald syndrome
*[[Hypertrophic cardiomyopathy]]
*[[Hypertrophic cardiomyopathy]]
*Hypomastia
 
*[[Idiopathic]]
*[[Idiopathic]]
*[[Infective Endocarditis]]
*[[Infective Endocarditis]]
*[[Leopard syndrome]]
*[[Leopard syndrome]]
*[[Marfan syndrome]]
*[[Marfan syndrome]]
{{ColBreak}}
 
*Marfan-like syndrome, Boileau type
*Marfan-like syndrome, Boileau type
*[[MASS phenotype]]
*[[MASS phenotype]]
*[[Mitral valve prolapse, familial, autosomal dominant]]
*[[Mitral valve prolapse, familial, autosomal dominant]]
*[[Mitral valve prolapse, familial, X linked]]
*[[Mitral valve prolapse, familial, X linked]]
*[[Mixed connective tissue disease]]
*[[Mixed connective tissue disease]]
*Myxomatous  [[Mitral valve prolapse ]]
*[[osteogenesis imperfecta]]
*[[Papillary muscle dysfunction]]
*[[Pectus excavatum]]
*[[Polyarteritis nodosa]]
*[[Polycystic kidney disease]]
*[[Pregnancy]]
*[[pseudoxanthoma elasticum]]
*[[Rheumatic heart disease]]
*Ruptured chordae
*[[Scoliosis]]
*[[Scurvy]]
*Severe [[mitral annular calcification ]]
*[[Sickle cell disease ]]
*[[SLE]]
*[[Spastic ataxia]] Charlevoix-Saguenay type
*[[ST Elevation Myocardial Infarction Complications]]
*Stickler Syndrome
*[[Trauma ]]
*[[Turner Syndrome]]
*Von Willebrand syndrome
{{EndMultiCol}}


*[[Myxomatous degeneration|Myxomatous]] [[mitral valve prolapse ]]


*[[Osteogenesis imperfecta]]


*[[Papillary muscle dysfunction]]


*[[Pectus excavatum]]


{{col-break|width=33%}}


*[[Polyarteritis nodosa]]


*[[Polycystic kidney disease]]


*[[Pregnancy]]


*[[Pseudoxanthoma elasticum]]


*[[Rheumatic heart disease]]


*Ruptured chordae


*[[Scoliosis]]


*[[Scurvy]]


*Severe [[mitral annular calcification ]]


*[[Sickle cell disease ]]


*[[SLE]]


*[[Spastic ataxia]] Charlevoix-Saguenay type


*[[ST elevation myocardial infarction]]


*Stickler syndrome


*[[Trauma ]]


*[[Turner Syndrome]]


*[[Von Willebrand disease]]


{{col-end}}


==References==


{{reflist|2}}


{{WH}}


*[[Marfan-like syndrome, Boileau type]]
*[[MASS phenotype]]
*[[Mitral valve prolapse, familial, autosomal dominant]]
*[[Mitral valve prolapse, familial, X linked]]
*[[Mixed connective tissue disease]]
*[[myxomatous  Mitral valve prolapse ]]
*[[osteogenesis imperfecta]]
*[[Papillary muscle dysfunction]]
*[[Pectus excavatum]]
*[[Polyarteritis nodosa]]
*[[Polycystic kidney disease]]
*[[Pregnancy]]
*[[pseudoxanthoma elasticum]]
*[[Rheumatic heart disease]]
*[[Ruptured chordae ]]
*[[Scoliosis]]
*[[Scurvy]]
*[[Severe mitral annular calcification ]]
*[[Sickle cell disease ]]
*[[SLE]]
*[[Spastic ataxia, Charlevoix-Saguenay type]]
*[[ST Elevation Myocardial Infarction Complications]]
*[[Stickler Syndrome]]
*[[Trauma ]]
*[[Turner Syndrome]]
*[[Von Willebrand syndrome ]]
{{EndMultiCol}}
==References==
{{reflist|2}}
[[Category:Needs content]]
{{WH}}
{{WS}}
{{WS}}

Latest revision as of 13:43, 16 July 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Farman Khan, MD, MRCP [2]

Overview

Mitral valve prolapse (MVP) is a valvular heart disease that is considered to be mainly hereditary. Myxomatous degeneration of the mitral valve is a common cause of MVP. Other less common causes of MVP include connective tissue diseases such as Marfan's syndrome, Ehlers Danlos syndrome and osteogenesis imperfecta, as well as damage to the mitral valve secondary to infarction, rheumatic heart disease, hypertrophic cardiomyopathy and trauma.

Causes

Common Causes

Causes by Organ System

Cardiovascular myxomatous of the mitral valve, myocardial infarction, severe mitral annular calcification, damaged chordae tendineae, rheumatic heart disease, papillary muscle dysfunction, hypertrophic cardiomyopathy, forme fruste Barlow disease, Ebstein's anomaly , cardiomegaly, bacterial endocarditis, congenital heart disease
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine Graves disease
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic Turner Syndrome, spastic ataxia, Charlevoix-Saguenay type, osteogenesis imperfecta, X-linked familial mitral valve prolapse, autosomal dominant familial mitral valve prolapse, MASS phenotype, Marfan syndrome, Marfan-like syndrome Boileau type, Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome
Hematologic Von Willebrand disease, sickle cell disease
Iatrogenic No underlying causes
Infectious Disease Infective endocarditis, acute rheumatic fever
Musculoskeletal/Orthopedic Dermato-cardio-skeletal syndrome Borrone type
Neurologic No underlying causes
Nutritional/Metabolic Scurvy
Obstetric/Gynecologic Pregnancy
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte Polycystic kidney disease
Rheumatology/Immunology/Allergy SLE, pseudoxanthoma elasticum, polyarteritis nodosa, connective tissue disease, mixed connective tissue disease, Ehlers-Danlos syndrome type I, Ehlers-Danlos syndrome type II, Ehlers-Danlos syndrome Type V
Sexual No underlying causes
Trauma Trauma to mitral valve
Urologic No underlying causes
Miscellaneous Stickler Syndrome, Leopard syndrome, idiopathic, fibroelastic deficiency, Dahlberg syndrome, Beals syndrome

Causes in Alphabetical Order

References

Template:WH

Template:WS

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