Mitral valve prolapse causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Mitral valve prolapse}} | {{Mitral valve prolapse}} | ||
{{CMG}}; {{FK}} | |||
==Overview== | |||
[[Mitral valve prolapse]] (MVP) is a [[valvular heart disease]] that is considered to be mainly hereditary. [[Myxomatous degeneration]] of the [[mitral valve]] is a common cause of MVP. Other less common causes of MVP include [[connective tissue diseases]] such as [[Marfan's syndrome]], [[Ehlers Danlos syndrome]] and [[osteogenesis imperfecta]], as well as damage to the [[mitral valve]] secondary to [[infarction]], [[rheumatic heart disease]], [[hypertrophic cardiomyopathy]] and [[trauma]]. | |||
==Causes== | |||
== | ===Common Causes=== | ||
===Common Causes === | * [[Marfan's syndrome]] | ||
* [[Myxomatous degeneration]] of the mitral valve | |||
* [[Papillary muscle]] infarction | |||
* [[Marfan's | * [[Papillary muscle]] trauma | ||
* Myxomatous | |||
* Papillary muscle infarction | |||
* Papillary muscle trauma | |||
===Causes by Organ System=== | ===Causes by Organ System=== | ||
{|style="width:82%; height:100px" border="1" | {|style="width:82%; height:100px" border="1" | ||
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | ||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | | |||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |[[Myxomatous degeneration|myxomatous]] of the [[mitral valve]], [[myocardial infarction]], severe [[mitral annular calcification]], damaged [[chordae tendineae]], [[rheumatic heart disease]], [[papillary muscle dysfunction]], [[hypertrophic cardiomyopathy]], forme fruste Barlow disease, [[Ebstein's anomaly ]], [[cardiomegaly]], [[bacterial endocarditis]], [[congenital heart disease]] | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Chemical/Poisoning''' | | '''Chemical/Poisoning''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Dental''' | | '''Dental''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Dermatologic''' | | '''Dermatologic''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Ear Nose Throat''' | | '''Ear Nose Throat''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| | |||
|bgcolor="Beige"|[[Graves disease]] | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Gastroenterologic''' | | '''Gastroenterologic''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| | |||
|bgcolor="Beige"|[[Turner Syndrome]], [[spastic ataxia]], Charlevoix-Saguenay type, [[osteogenesis imperfecta]], [[Mitral valve prolapse, familial, X linked|X-linked familial mitral valve prolapse]], [[Mitral valve prolapse, familial, autosomal dominant|autosomal dominant familial mitral valve prolapse]], [[MASS phenotype]], [[Marfan syndrome]], Marfan-like syndrome Boileau type, Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
|bgcolor="Beige"| | |||
|bgcolor="Beige"|[[Von Willebrand disease]], [[sickle cell disease ]] | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Iatrogenic''' | | '''Iatrogenic''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"|[[Infective | |||
|bgcolor="Beige"|[[Infective endocarditis]], [[acute rheumatic fever]] | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal/Orthopedic''' | | '''Musculoskeletal/Orthopedic''' | ||
|bgcolor="Beige"| | |||
|bgcolor="Beige"|Dermato-cardio-skeletal syndrome Borrone type | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Neurologic''' | | '''Neurologic''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Nutritional/Metabolic''' | | '''Nutritional/Metabolic''' | ||
|bgcolor="Beige"|[[Scurvy]] | |bgcolor="Beige"|[[Scurvy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Obstetric/Gynecologic''' | | '''Obstetric/Gynecologic''' | ||
|bgcolor="Beige"|[[Pregnancy]] | |bgcolor="Beige"|[[Pregnancy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Oncologic''' | | '''Oncologic''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Ophthalmologic''' | | '''Ophthalmologic''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Overdose/Toxicity''' | | '''Overdose/Toxicity''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Psychiatric''' | | '''Psychiatric''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Pulmonary''' | | '''Pulmonary''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Renal/Electrolyte''' | | '''Renal/Electrolyte''' | ||
|bgcolor="Beige"|[[Polycystic kidney disease]] | |bgcolor="Beige"|[[Polycystic kidney disease]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Rheumatology/Immunology/Allergy''' | | '''Rheumatology/Immunology/Allergy''' | ||
|bgcolor="Beige"|[[SLE]] , [[pseudoxanthoma elasticum]] , [[ | |||
|bgcolor="Beige"|[[SLE]], [[pseudoxanthoma elasticum]], [[polyarteritis nodosa]], [[connective tissue disease]], [[mixed connective tissue disease]], [[Ehlers-Danlos syndrome]] type I, [[Ehlers-Danlos syndrome]] type II, [[Ehlers-Danlos syndrome]] Type V | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Sexual''' | | '''Sexual''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Trauma''' | | '''Trauma''' | ||
|bgcolor="Beige"| | |||
|bgcolor="Beige"|[[Trauma ]] to [[mitral valve]] | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Urologic''' | | '''Urologic''' | ||
|bgcolor="Beige"| No underlying causes | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"|Stickler Syndrome , [[Leopard syndrome]] , [[ | |||
|bgcolor="Beige"|Stickler Syndrome, [[Leopard syndrome]], [[idiopathic]], fibroelastic deficiency, Dahlberg syndrome, [[Beals syndrome]] | |||
|- | |- | ||
|} | |} | ||
===Causes in Alphabetical Order=== | ===Causes in Alphabetical Order=== | ||
{{ | |||
{{col-begin|width=84%}} | |||
{{col-break|width=33%}} | |||
*[[Acute myocardial ischemia]] | *[[Acute myocardial ischemia]] | ||
*[[Acute rheumatic fever]] | *[[Acute rheumatic fever]] | ||
*Adult [[polycystic kidney disease]] | *Adult [[polycystic kidney disease]] | ||
*Associated with [[congenital heart disease]] | *Associated with [[congenital heart disease]] | ||
*Associated with [[connective tissue disease]] | *Associated with [[connective tissue disease]] | ||
*[[Bacterial | |||
*[[Bacterial endocarditis]] | |||
*[[Beals syndrome]] | *[[Beals syndrome]] | ||
*[[Cardiomegaly]] | *[[Cardiomegaly]] | ||
*Chordal rupture | *Chordal rupture | ||
*Dahlberg syndrome | *Dahlberg syndrome | ||
*Dermato-cardio-skeletal syndrome Borrone type | *Dermato-cardio-skeletal syndrome Borrone type | ||
*[[Ebstein's anomaly ]] | *[[Ebstein's anomaly ]] | ||
*[[Ehlers-Danlos syndrome]] Type I | *[[Ehlers-Danlos syndrome]] Type I | ||
*[[Ehlers-Danlos syndrome]] type II | *[[Ehlers-Danlos syndrome]] type II | ||
*[[Ehlers-Danlos syndrome]] type V | *[[Ehlers-Danlos syndrome]] type V | ||
*Fibroelastic deficiency | *Fibroelastic deficiency | ||
*Forme fruste | |||
*Forme fruste Barlow disease | |||
{{col-break|width=33%}} | |||
*Furlong-Kurczynski-Hennessy syndrome | *Furlong-Kurczynski-Hennessy syndrome | ||
*[[Graves disease]] | *[[Graves disease]] | ||
*Hunter-Mcdonald syndrome | *Hunter-Mcdonald syndrome | ||
*[[Hypertrophic cardiomyopathy]] | *[[Hypertrophic cardiomyopathy]] | ||
*[[Idiopathic]] | *[[Idiopathic]] | ||
*[[Infective Endocarditis]] | *[[Infective Endocarditis]] | ||
*[[Leopard syndrome]] | *[[Leopard syndrome]] | ||
*[[Marfan syndrome]] | *[[Marfan syndrome]] | ||
*Marfan-like syndrome, Boileau type | *Marfan-like syndrome, Boileau type | ||
*[[MASS phenotype]] | *[[MASS phenotype]] | ||
*[[Mitral valve prolapse, familial, autosomal dominant]] | *[[Mitral valve prolapse, familial, autosomal dominant]] | ||
*[[Mitral valve prolapse, familial, X linked]] | *[[Mitral valve prolapse, familial, X linked]] | ||
*[[Mixed connective tissue disease]] | *[[Mixed connective tissue disease]] | ||
*[[Myxomatous degeneration|Myxomatous]] [[mitral valve prolapse ]] | |||
*[[Osteogenesis imperfecta]] | |||
*[[Papillary muscle dysfunction]] | |||
*[[Pectus excavatum]] | |||
{{col-break|width=33%}} | |||
*[[Polyarteritis nodosa]] | |||
*[[Polycystic kidney disease]] | |||
*[[Pregnancy]] | |||
*[[Pseudoxanthoma elasticum]] | |||
*[[Rheumatic heart disease]] | |||
*Ruptured chordae | |||
*[[Scoliosis]] | |||
*[[Scurvy]] | |||
*Severe [[mitral annular calcification ]] | |||
*[[Sickle cell disease ]] | |||
*[[SLE]] | |||
*[[Spastic ataxia]] Charlevoix-Saguenay type | |||
*[[ST elevation myocardial infarction]] | |||
*Stickler syndrome | |||
*[[Trauma ]] | |||
*[[Turner Syndrome]] | |||
*[[Von Willebrand disease]] | |||
{{col-end}} | |||
==References== | |||
{{reflist|2}} | |||
{{WH}} | |||
{{WS}} | {{WS}} |
Latest revision as of 13:43, 16 July 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Farman Khan, MD, MRCP [2]
Overview
Mitral valve prolapse (MVP) is a valvular heart disease that is considered to be mainly hereditary. Myxomatous degeneration of the mitral valve is a common cause of MVP. Other less common causes of MVP include connective tissue diseases such as Marfan's syndrome, Ehlers Danlos syndrome and osteogenesis imperfecta, as well as damage to the mitral valve secondary to infarction, rheumatic heart disease, hypertrophic cardiomyopathy and trauma.
Causes
Common Causes
- Marfan's syndrome
- Myxomatous degeneration of the mitral valve
- Papillary muscle infarction
- Papillary muscle trauma
Causes by Organ System
Cardiovascular | myxomatous of the mitral valve, myocardial infarction, severe mitral annular calcification, damaged chordae tendineae, rheumatic heart disease, papillary muscle dysfunction, hypertrophic cardiomyopathy, forme fruste Barlow disease, Ebstein's anomaly , cardiomegaly, bacterial endocarditis, congenital heart disease |
Chemical/Poisoning | No underlying causes |
Dental | No underlying causes |
Dermatologic | No underlying causes |
Drug Side Effect | No underlying causes |
Ear Nose Throat | No underlying causes |
Endocrine | Graves disease |
Environmental | No underlying causes |
Gastroenterologic | No underlying causes |
Genetic | Turner Syndrome, spastic ataxia, Charlevoix-Saguenay type, osteogenesis imperfecta, X-linked familial mitral valve prolapse, autosomal dominant familial mitral valve prolapse, MASS phenotype, Marfan syndrome, Marfan-like syndrome Boileau type, Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome |
Hematologic | Von Willebrand disease, sickle cell disease |
Iatrogenic | No underlying causes |
Infectious Disease | Infective endocarditis, acute rheumatic fever |
Musculoskeletal/Orthopedic | Dermato-cardio-skeletal syndrome Borrone type |
Neurologic | No underlying causes |
Nutritional/Metabolic | Scurvy |
Obstetric/Gynecologic | Pregnancy |
Oncologic | No underlying causes |
Ophthalmologic | No underlying causes |
Overdose/Toxicity | No underlying causes |
Psychiatric | No underlying causes |
Pulmonary | No underlying causes |
Renal/Electrolyte | Polycystic kidney disease |
Rheumatology/Immunology/Allergy | SLE, pseudoxanthoma elasticum, polyarteritis nodosa, connective tissue disease, mixed connective tissue disease, Ehlers-Danlos syndrome type I, Ehlers-Danlos syndrome type II, Ehlers-Danlos syndrome Type V |
Sexual | No underlying causes |
Trauma | Trauma to mitral valve |
Urologic | No underlying causes |
Miscellaneous | Stickler Syndrome, Leopard syndrome, idiopathic, fibroelastic deficiency, Dahlberg syndrome, Beals syndrome |
Causes in Alphabetical Order
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