Mitral valve prolapse causes: Difference between revisions

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==Overview==
==Overview==
[[Mitral valve prolapse]] (MVP) is a [[valvular heart disease]] characterized by the displacement of an abnormally thickened [[mitral valve]] leaflet into the left atrium during [[systole]]. Common causes of MVP include [[Marfan's syndrome]], myxomatous degeneration of the valve, [[papillary muscle]] infarction and papillary muscle trauma.
[[Mitral valve prolapse]] (MVP) is a [[valvular heart disease]] that is considered to be mainly hereditary. [[Myxomatous degeneration]] of the [[mitral valve]] is a common cause of MVP. Other less common causes of MVP include [[connective tissue diseases]] such as [[Marfan's syndrome]], [[Ehlers Danlos syndrome]] and [[osteogenesis imperfecta]], as well as damage to the [[mitral valve]] secondary to [[infarction]], [[rheumatic heart disease]], [[hypertrophic cardiomyopathy]] and [[trauma]].
 
==Causes==
==Causes==
===Common Causes===
===Common Causes===
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|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''


|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |[[ST Elevation Myocardial Infarction Complications]] , Severe [[mitral annular calcification ]] , Ruptured chordae , [[Rheumatic heart disease]] , [[Papillary muscle dysfunction]] , myxomatous  [[Mitral valve prolapse ]] , [[Hypertrophic cardiomyopathy]] , Forme fruste [[Barlow disease]] , [[Ebstein's anomaly ]] , Chordal rupture , [[Cardiomegaly]] , [[Bacterial Endocarditis]] , Associated with [[congenital heart disease]], [[Acute myocardial ischemia]]
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |[[Myxomatous degeneration|myxomatous]] of the [[mitral valve]], [[myocardial infarction]], severe [[mitral annular calcification]], damaged [[chordae tendineae]], [[rheumatic heart disease]], [[papillary muscle dysfunction]], [[hypertrophic cardiomyopathy]], forme fruste Barlow disease, [[Ebstein's anomaly ]], [[cardiomegaly]], [[bacterial endocarditis]], [[congenital heart disease]]


|-
|-
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| '''Genetic'''
| '''Genetic'''


|bgcolor="Beige"|[[Turner Syndrome]] , [[Spastic ataxia]] Charlevoix-Saguenay type , [[osteogenesis imperfecta]] , [[Mitral valve prolapse]] familial, X linked, [[Mitral valve prolapse]] familial, autosomal dominant , [[MASS phenotype]], Marfan-like syndrome  Boileau type, [[Marfan syndrome]] , Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome
|bgcolor="Beige"|[[Turner Syndrome]], [[spastic ataxia]], Charlevoix-Saguenay type, [[osteogenesis imperfecta]], [[Mitral valve prolapse, familial, X linked|X-linked familial mitral valve prolapse]], [[Mitral valve prolapse, familial, autosomal dominant|autosomal dominant familial mitral valve prolapse]], [[MASS phenotype]], [[Marfan syndrome]], Marfan-like syndrome  Boileau type, Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome


|-
|-
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| '''Hematologic'''
| '''Hematologic'''


|bgcolor="Beige"|Von Willebrand syndrome , [[Sickle cell disease ]]
|bgcolor="Beige"|[[Von Willebrand disease]], [[sickle cell disease ]]


|-
|-
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| '''Infectious Disease'''
| '''Infectious Disease'''


|bgcolor="Beige"|[[Infective Endocarditis]] , [[Acute rheumatic fever]]
|bgcolor="Beige"|[[Infective endocarditis]], [[acute rheumatic fever]]


|-
|-
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| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''


|bgcolor="Beige"|[[Scoliosis]] , [[Pectus excavatum]] , Dermato-cardio-skeletal syndrome Borrone type
|bgcolor="Beige"|Dermato-cardio-skeletal syndrome Borrone type


|-
|-
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| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''


|bgcolor="Beige"|[[SLE]] , [[pseudoxanthoma elasticum]] , [[Polyarteritis nodosa]] , [[Mixed connective tissue disease]] , [[Ehlers-Danlos syndrome]] type V ,   [[Ehlers-Danlos syndrome]] type II , [[Ehlers-Danlos syndrome]] Type I , Associated with [[connective tissue disease]]
|bgcolor="Beige"|[[SLE]], [[pseudoxanthoma elasticum]], [[polyarteritis nodosa]], [[connective tissue disease]], [[mixed connective tissue disease]], [[Ehlers-Danlos syndrome]] type I, [[Ehlers-Danlos syndrome]] type II, [[Ehlers-Danlos syndrome]] Type V


|-
|-
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| '''Trauma'''
| '''Trauma'''


|bgcolor="Beige"|[[Trauma ]] to [[Mitral valve]]
|bgcolor="Beige"|[[Trauma ]] to [[mitral valve]]


|-
|-
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| '''Miscellaneous'''
| '''Miscellaneous'''


|bgcolor="Beige"|Stickler Syndrome , [[Leopard syndrome]] , [[Idiopathic]] , Fibroelastic deficiency , Dahlberg syndrome , [[Beals syndrome]]
|bgcolor="Beige"|Stickler Syndrome, [[Leopard syndrome]], [[idiopathic]], fibroelastic deficiency, Dahlberg syndrome, [[Beals syndrome]]


|-
|-
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*Associated with [[connective tissue disease]]
*Associated with [[connective tissue disease]]


*[[Bacterial Endocarditis]]
*[[Bacterial endocarditis]]


*[[Beals syndrome]]
*[[Beals syndrome]]
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*Fibroelastic deficiency
*Fibroelastic deficiency


*Forme fruste [[Barlow disease]]
*Forme fruste Barlow disease


{{col-break|width=33%}}
{{col-break|width=33%}}
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*[[Mixed connective tissue disease]]
*[[Mixed connective tissue disease]]


*Myxomatous [[Mitral valve prolapse ]]
*[[Myxomatous degeneration|Myxomatous]] [[mitral valve prolapse ]]


*[[Osteogenesis imperfecta]]
*[[Osteogenesis imperfecta]]
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*[[Spastic ataxia]] Charlevoix-Saguenay type
*[[Spastic ataxia]] Charlevoix-Saguenay type


*[[ST Elevation Myocardial Infarction Complications]]
*[[ST elevation myocardial infarction]]


*Stickler Syndrome
*Stickler syndrome


*[[Trauma ]]
*[[Trauma ]]
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*[[Turner Syndrome]]
*[[Turner Syndrome]]


*Von Willebrand syndrome
*[[Von Willebrand disease]]


{{col-end}}
{{col-end}}

Latest revision as of 13:43, 16 July 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Farman Khan, MD, MRCP [2]

Overview

Mitral valve prolapse (MVP) is a valvular heart disease that is considered to be mainly hereditary. Myxomatous degeneration of the mitral valve is a common cause of MVP. Other less common causes of MVP include connective tissue diseases such as Marfan's syndrome, Ehlers Danlos syndrome and osteogenesis imperfecta, as well as damage to the mitral valve secondary to infarction, rheumatic heart disease, hypertrophic cardiomyopathy and trauma.

Causes

Common Causes

Causes by Organ System

Cardiovascular myxomatous of the mitral valve, myocardial infarction, severe mitral annular calcification, damaged chordae tendineae, rheumatic heart disease, papillary muscle dysfunction, hypertrophic cardiomyopathy, forme fruste Barlow disease, Ebstein's anomaly , cardiomegaly, bacterial endocarditis, congenital heart disease
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine Graves disease
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic Turner Syndrome, spastic ataxia, Charlevoix-Saguenay type, osteogenesis imperfecta, X-linked familial mitral valve prolapse, autosomal dominant familial mitral valve prolapse, MASS phenotype, Marfan syndrome, Marfan-like syndrome Boileau type, Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome
Hematologic Von Willebrand disease, sickle cell disease
Iatrogenic No underlying causes
Infectious Disease Infective endocarditis, acute rheumatic fever
Musculoskeletal/Orthopedic Dermato-cardio-skeletal syndrome Borrone type
Neurologic No underlying causes
Nutritional/Metabolic Scurvy
Obstetric/Gynecologic Pregnancy
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte Polycystic kidney disease
Rheumatology/Immunology/Allergy SLE, pseudoxanthoma elasticum, polyarteritis nodosa, connective tissue disease, mixed connective tissue disease, Ehlers-Danlos syndrome type I, Ehlers-Danlos syndrome type II, Ehlers-Danlos syndrome Type V
Sexual No underlying causes
Trauma Trauma to mitral valve
Urologic No underlying causes
Miscellaneous Stickler Syndrome, Leopard syndrome, idiopathic, fibroelastic deficiency, Dahlberg syndrome, Beals syndrome

Causes in Alphabetical Order

References

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