Sinus bradycardia pathophysiology: Difference between revisions
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Created page with "__NOTOC__ {{Sinus bradycardia}} {{SI}} {{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}} ==Overview== ==Pathophysiology== This rhythm may be caused by one of the following: *..." |
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* Sinus bradycardia is a normal finding in a healthy, well-conditioned athlete | * Sinus bradycardia is a normal finding in a healthy, well-conditioned athlete | ||
The [[HCN4]] genetic variant is associated with sinus bradycardia. Certain sodium [[channelopathies]] are associated with sinus bradycardia.<ref name="pmid16407510">{{cite journal | author = Milanesi R, Baruscotti M, Gnecchi-Ruscone T, DiFrancesco D | title = Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel | journal = [[The New England Journal of Medicine]] | volume = 354 | issue = 2 | pages = 151–7 | year = 2006 | month = January | pmid = 16407510 | doi = 10.1056/NEJMoa052475 | url =http://dx.doi.org/10.1056/NEJMoa052475 | issn = | accessdate = 2011-02-23}}</ref> | |||
==References== | ==References== |
Latest revision as of 20:55, 26 August 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Pathophysiology
This rhythm may be caused by one of the following:
- Increased vagal tone
- Intrinsic disease of the SA node
- An effect of drugs, such as the use of digitalis or beta-blockers
- Sleep
- Sinus bradycardia is a normal finding in a healthy, well-conditioned athlete
The HCN4 genetic variant is associated with sinus bradycardia. Certain sodium channelopathies are associated with sinus bradycardia.[1]
References
- ↑ Milanesi R, Baruscotti M, Gnecchi-Ruscone T, DiFrancesco D (2006). "Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel". The New England Journal of Medicine. 354 (2): 151–7. doi:10.1056/NEJMoa052475. PMID 16407510. Retrieved 2011-02-23. Unknown parameter
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