Sandbox/23: Difference between revisions
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|+ '''Manifestations of Lyme Disease by Stage<ref name="Steere-1989">{{Cite journal | last1 = Steere | first1 = AC. | title = Lyme disease. | journal = N Engl J Med | volume = 321 | issue = 9 | pages = 586-96 | month = Aug | year = 1989 | doi = 10.1056/NEJM198908313210906 |PMID = 2668764 }}</ref>''' | |+ '''Manifestations of Lyme Disease by Stage<ref name="Steere-1989">{{Cite journal | last1 = Steere | first1 = AC. | title = Lyme disease. | journal = N Engl J Med | volume = 321 | issue = 9 | pages = 586-96 | month = Aug | year = 1989 | doi = 10.1056/NEJM198908313210906 |PMID = 2668764 }}</ref>''' | ||
|- | |- | ||
| '''System''' || '''Stage 1 (Localized Infection)''' || '''Stage 2 (Disseminated Infection)''' || '''Stage 3 (Persistent Infection)''' | | style="background:LightSlateGray; width:15%;" | '''System''' || style="background: #efefef; width:25%;" | '''Stage 1 (Localized Infection)''' || style="background: #efefef; width:25%;" | '''Stage 2 (Disseminated Infection)''' || style="background: #ffdead; width:35%" | '''Stage 3 (Persistent Infection)''' | ||
|- | |- | ||
| ''Skin'' ||valign="top"| ▸ Erythema migrans ||valign="top"| ▸ Secondary annular lesions <BR> ▸ Malar rash <BR> ▸ Diffuse erythema or urticaria <BR> ▸ Evanescent lesions <BR> ▸ Lymphocytoma ||valign="top"| ▸ Acrodermatitis chronica atrophicans <BR> ▸ Localized scleroderma-like lesions | | ''Skin'' ||valign="top"| ▸ [[Erythema migrans]] ||valign="top"| ▸ Secondary annular lesions <BR> ▸ [[Malar rash]] <BR> ▸ Diffuse [[erythema]] or [[urticaria]] <BR> ▸ Evanescent lesions <BR> ▸ Lymphocytoma ||valign="top"| ▸ [[Acrodermatitis chronica atrophicans]] <BR> ▸ Localized [[scleroderma]]-like lesions | ||
|- | |- | ||
| ''Musculoskeletal'' || ||valign="top"| ▸ Migratory arthralgia <BR> ▸ Brief arthritis attacks <BR> ▸ Myositis <BR> ▸ Osteomyelitis <BR> ▸ Panniculitis ||valign="top"| ▸ Prolonged arthritis attacks <BR> ▸ Chronic arthritis <BR> ▸ Peripheral enthesopathy <BR> ▸ Periostitis or joint subluxations below acrodermatitis | | ''Musculoskeletal'' || ||valign="top"| ▸ Migratory [[arthralgia]] <BR> ▸ Brief [[arthritis]] attacks <BR> ▸ [[Myositis]] <BR> ▸ [[Osteomyelitis]] <BR> ▸ [[Panniculitis]] ||valign="top"| ▸ Prolonged [[arthritis]] attacks <BR> ▸ Chronic [[arthritis]] <BR> ▸ Peripheral [[enthesopathy]] <BR> ▸ [[Periostitis]] or joint subluxations below acrodermatitis | ||
|- | |- | ||
| ''Neurologic'' || ||valign="top"| ▸ Meningitis <BR> ▸ Cranial neuritis or Bell's palsy <BR> ▸ Motor or sensory radiculoneuritis <BR> ▸ Encephalitis <BR> ▸ Mononeuritis multiplex <BR> ▸ Pseudotumor cerebri <BR> ▸ Myelitis <BR> ▸ Chorea <BR> ▸ Cerebellar ataxia||valign="top"| ▸ Chronic encephalomyelitis <BR> ▸ Spastic parapareses <BR> ▸ Ataxic gait <BR> ▸ Mental disorders <BR> ▸ Chronic axonal polyradiculopathy <BR> ▸ Dementia | | ''Neurologic'' || ||valign="top"| ▸ [[Meningitis]] <BR> ▸ Cranial [[neuritis]] or [[Bell's palsy]] <BR> ▸ Motor or sensory radiculoneuritis <BR> ▸ [[Encephalitis]] <BR> ▸ [[Mononeuritis multiplex]] <BR> ▸ [[Pseudotumor cerebri]] <BR> ▸ [[Myelitis]] <BR> ▸ [[Chorea]] <BR> ▸ [[Cerebellar ataxia]] ||valign="top"| ▸ Chronic [[encephalomyelitis]] <BR> ▸ Spastic parapareses <BR> ▸ [[Ataxic gait]] <BR> ▸ Mental disorders <BR> ▸ Chronic axonal polyradiculopathy <BR> ▸ [[Dementia]] | ||
|- | |- | ||
| ''Lymphatic'' ||valign="top"| ▸ Regional lymphadenopathy ||valign="top"| ▸ Regional or generalized lymphadenopathy <BR> ▸ Splenomegaly || | | ''Lymphatic'' ||valign="top"| ▸ Regional [[lymphadenopathy]] ||valign="top"| ▸ Regional or generalized [[lymphadenopathy]] <BR> ▸ [[Splenomegaly]] || | ||
|- | |- | ||
| ''Heart'' || ||valign="top"| ▸ Atrioventricular | | ''Heart'' || ||valign="top"| ▸ [[Atrioventricular block]] <BR> ▸ [[Myopericarditis]] <BR> ▸ Pancarditis || | ||
|- | |- | ||
| ''Eyes'' || ||valign="top"| ▸ Conjunctivitis <BR> ▸ Iritis <BR> ▸ Choroiditis | | ''Eyes'' || ||valign="top"| ▸ [[Conjunctivitis]] <BR> ▸ [[Iritis]] <BR> ▸ [[Choroiditis]] <BR> ▸ [[Retinal hemorrhage]] or [[retinal detachment]] <BR> ▸ Panophthalmitis ||valign="top"| ▸ [[Keratitis]] | ||
|- | |- | ||
| ''Liver'' || || ▸ Mild or recurrent hepatitis || | | ''Liver'' || || ▸ Mild or recurrent [[hepatitis]] || | ||
|- | |- | ||
| ''Respiratory'' || ||valign="top"| ▸ Nonexudative sore throat <BR> ▸ Nonproductive cough <BR> ▸ Adult respiratory distress syndrome || | | ''Respiratory'' || ||valign="top"| ▸ Nonexudative [[sore throat]] <BR> ▸ Nonproductive [[cough]] <BR> ▸ [[Adult respiratory distress syndrome]] || | ||
|- | |- | ||
| ''Kidney'' || ||valign="top"| ▸ Microscopic hematuria or proteinuria || | | ''Kidney'' || ||valign="top"| ▸ Microscopic [[hematuria]] or [[proteinuria]] || | ||
|- | |- | ||
| ''Genitourinary'' || || ▸ Orchitis || | | ''Genitourinary'' || || ▸ [[Orchitis]] || | ||
|- | |- | ||
| ''Constitutional systems'' || ▸ Minor || ▸ Severe malaise and fatigue || ▸ Fatigue | | ''Constitutional systems'' || ▸ Minor || ▸ Severe [[malaise]] and [[fatigue]] || ▸ [[Fatigue]] | ||
|} | |} | ||
Latest revision as of 20:19, 13 December 2013
| System | Stage 1 (Localized Infection) | Stage 2 (Disseminated Infection) | Stage 3 (Persistent Infection) |
| Skin | ▸ Erythema migrans | ▸ Secondary annular lesions ▸ Malar rash ▸ Diffuse erythema or urticaria ▸ Evanescent lesions ▸ Lymphocytoma |
▸ Acrodermatitis chronica atrophicans ▸ Localized scleroderma-like lesions |
| Musculoskeletal | ▸ Migratory arthralgia ▸ Brief arthritis attacks ▸ Myositis ▸ Osteomyelitis ▸ Panniculitis |
▸ Prolonged arthritis attacks ▸ Chronic arthritis ▸ Peripheral enthesopathy ▸ Periostitis or joint subluxations below acrodermatitis | |
| Neurologic | ▸ Meningitis ▸ Cranial neuritis or Bell's palsy ▸ Motor or sensory radiculoneuritis ▸ Encephalitis ▸ Mononeuritis multiplex ▸ Pseudotumor cerebri ▸ Myelitis ▸ Chorea ▸ Cerebellar ataxia |
▸ Chronic encephalomyelitis ▸ Spastic parapareses ▸ Ataxic gait ▸ Mental disorders ▸ Chronic axonal polyradiculopathy ▸ Dementia | |
| Lymphatic | ▸ Regional lymphadenopathy | ▸ Regional or generalized lymphadenopathy ▸ Splenomegaly |
|
| Heart | ▸ Atrioventricular block ▸ Myopericarditis ▸ Pancarditis |
||
| Eyes | ▸ Conjunctivitis ▸ Iritis ▸ Choroiditis ▸ Retinal hemorrhage or retinal detachment ▸ Panophthalmitis |
▸ Keratitis | |
| Liver | ▸ Mild or recurrent hepatitis | ||
| Respiratory | ▸ Nonexudative sore throat ▸ Nonproductive cough ▸ Adult respiratory distress syndrome |
||
| Kidney | ▸ Microscopic hematuria or proteinuria | ||
| Genitourinary | ▸ Orchitis | ||
| Constitutional systems | ▸ Minor | ▸ Severe malaise and fatigue | ▸ Fatigue |