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{| border="1" cellpadding="4" cellspacing="0" align="center" style="font-size:80%;"
{| border="1" cellpadding="4" cellspacing="0" align="center" style="font-size:85%;"
|+ '''Manifestations of Lyme Disease by Stage<ref name="Steere-1989">{{Cite journal  | last1 = Steere | first1 = AC. | title = Lyme disease. | journal = N Engl J Med | volume = 321 | issue = 9 | pages = 586-96 | month = Aug | year = 1989 | doi = 10.1056/NEJM198908313210906 |PMID = 2668764 }}</ref>'''
|+ '''Manifestations of Lyme Disease by Stage<ref name="Steere-1989">{{Cite journal  | last1 = Steere | first1 = AC. | title = Lyme disease. | journal = N Engl J Med | volume = 321 | issue = 9 | pages = 586-96 | month = Aug | year = 1989 | doi = 10.1056/NEJM198908313210906 |PMID = 2668764 }}</ref>'''
|-
|-
| '''System''' || '''Stage 1 (Localized Infection)''' || '''Stage 2 (Disseminated Infection)''' || '''Stage 3 (Persistent Infection)'''
| style="background:LightSlateGray; width:15%;" | '''System''' || style="background: #efefef; width:25%;" | '''Stage 1 (Localized Infection)''' || style="background: #efefef; width:25%;" | '''Stage 2 (Disseminated Infection)''' || style="background: #ffdead; width:35%" | '''Stage 3 (Persistent Infection)'''
|-
|-
| ''Skin'' ||valign="top"| ▸ [[Erythema migrans]] ||valign="top"| ▸ Secondary annular lesions <BR> ▸ [[Malar rash]] <BR> ▸ Diffuse [[erythema]] or [[urticaria]] <BR> ▸ Evanescent lesions <BR> ▸ Lymphocytoma ||valign="top"| ▸ [[Acrodermatitis chronica atrophicans]] <BR> ▸ Localized [[scleroderma]]-like lesions
| ''Skin'' ||valign="top"| ▸ [[Erythema migrans]] ||valign="top"| ▸ Secondary annular lesions <BR> ▸ [[Malar rash]] <BR> ▸ Diffuse [[erythema]] or [[urticaria]] <BR> ▸ Evanescent lesions <BR> ▸ Lymphocytoma ||valign="top"| ▸ [[Acrodermatitis chronica atrophicans]] <BR> ▸ Localized [[scleroderma]]-like lesions

Latest revision as of 20:19, 13 December 2013





Manifestations of Lyme Disease by Stage[1]
System Stage 1 (Localized Infection) Stage 2 (Disseminated Infection) Stage 3 (Persistent Infection)
Skin Erythema migrans ▸ Secondary annular lesions
Malar rash
▸ Diffuse erythema or urticaria
▸ Evanescent lesions
▸ Lymphocytoma
Acrodermatitis chronica atrophicans
▸ Localized scleroderma-like lesions
Musculoskeletal ▸ Migratory arthralgia
▸ Brief arthritis attacks
Myositis
Osteomyelitis
Panniculitis
▸ Prolonged arthritis attacks
▸ Chronic arthritis
▸ Peripheral enthesopathy
Periostitis or joint subluxations below acrodermatitis
Neurologic Meningitis
▸ Cranial neuritis or Bell's palsy
▸ Motor or sensory radiculoneuritis
Encephalitis
Mononeuritis multiplex
Pseudotumor cerebri
Myelitis
Chorea
Cerebellar ataxia
▸ Chronic encephalomyelitis
▸ Spastic parapareses
Ataxic gait
▸ Mental disorders
▸ Chronic axonal polyradiculopathy
Dementia
Lymphatic ▸ Regional lymphadenopathy ▸ Regional or generalized lymphadenopathy
Splenomegaly
Heart Atrioventricular block
Myopericarditis
▸ Pancarditis
Eyes Conjunctivitis
Iritis
Choroiditis
Retinal hemorrhage or retinal detachment
▸ Panophthalmitis
Keratitis
Liver ▸ Mild or recurrent hepatitis
Respiratory ▸ Nonexudative sore throat
▸ Nonproductive cough
Adult respiratory distress syndrome
Kidney ▸ Microscopic hematuria or proteinuria
Genitourinary Orchitis
Constitutional systems ▸ Minor ▸ Severe malaise and fatigue Fatigue
  1. Steere, AC. (1989). "Lyme disease". N Engl J Med. 321 (9): 586–96. doi:10.1056/NEJM198908313210906. PMID 2668764. Unknown parameter |month= ignored (help)