Spectinomycin: Difference between revisions

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{{drugbox
__NOTOC__
| IUPAC_name = (2''R'',4a''R'',5a''R'',6''S'',7''S'',8''R'',9''S'',9a''R'',10a''S'')-<br>4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)<br>decahydro-4''H''-pyrano[2,3-b][1,4]benzodioxin-4-one
{{Spectinomycin}}
| image = Spectinomycin.svg
{{CMG}}
| CAS_number = 1695-77-8
| ATC_prefix = J01
| ATC_suffix = XX04
| ATC_supplemental =
| PubChem = 15541
| DrugBank = APRD01232
| C = 14 | H = 24 | N = 2 | O = 7
| molecular_weight = 332.35 g/mol
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| pregnancy_US = B
| legal_status =
| routes_of_administration =
}}
{{SI}}


==Overview==
Spectinomycin is an [[aminocyclitol]] [[antibiotic]] produced by the [[bacteria|bacterium]] ''[[Streptomyces spectabilis]]''.


'''Spectinomycin''' (marketed as the [[hydrochloride]] salt '''spectinomycin hydrochloride''' under the trade name '''Trobicin''') is an [[aminocyclitol]] [[antibiotic]] produced by the [[bacteria|bacterium]] ''[[Streptomyces spectabilis]]''. 
==Category==
Aminocyclitol


==Mechanism==
==US Brand Names==
It binds to the [[30S]] [[ribosome|ribosomal]] subunit in invading bacteria and interrupts protein synthesis. 
TROBICIN<sup>®</sup> (''DISCONTINUED'')


==Uses==
==FDA Package Insert==
It is given by [[Injection (medicine)|injection]] to treat [[gonorrhea]], especially in patients who are allergic to [[penicillin]]s. 
'''  [[Spectinomycin description|Description]]'''
'''| [[Spectinomycin clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Spectinomycin microbiology|Microbiology]]'''
'''| [[Spectinomycin indications and usage|Indications and Usage]]'''
'''| [[Spectinomycin contraindications|Contraindications]]'''
'''| [[Spectinomycin warnings and precautions|Warnings and Precautions]]'''
'''| [[Spectinomycin adverse reactions|Adverse Reactions]]'''
'''| [[Spectinomycin overdosage|Overdosage]]'''
'''| [[Spectinomycin dosage and administration|Dosage and Administration]]'''
'''| [[Spectinomycin how supplied|How Supplied]]'''


==Side effects==
==Mechanisms of Action==
Side effects include [[pruritus|itching]], [[chills]], stomach-ash, and [[erythema|red rash]].
It binds to the [[30S]] [[ribosome|ribosomal]] subunit in invading bacteria and interrupts protein synthesis.
 
==References==
{{Reflist|2}}


{{AminoglycosideAntiBiotics}}
{{Other antibacterials}}
[[Category:Antibiotics]]
[[Category:Antibiotics]]
 
[[Category:Wikinfect]]
 
 
[[de:Spectinomycin]]
 
{{WH}}
{{WikiDoc Sources}}

Latest revision as of 02:48, 4 January 2014

Spectinomycin
TROBICIN® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Overdosage
Dosage and Administration
How Supplied

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Spectinomycin is an aminocyclitol antibiotic produced by the bacterium Streptomyces spectabilis.

Category

Aminocyclitol

US Brand Names

TROBICIN® (DISCONTINUED)

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Dosage and Administration | How Supplied

Mechanisms of Action

It binds to the 30S ribosomal subunit in invading bacteria and interrupts protein synthesis.

References

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