Penicillin G sodium: Difference between revisions
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{{Penicillin G sodium}} | |||
{{CMG}}; {{AE}} {{MM}} | |||
==Overview== | |||
Penicillin G sodium, a water soluble benzylpenicillin,itis bactericidal against penicillin-susceptible microorganisms during the stage of active multiplication. Penicillin G is typically given [[parenteral|parenterally]], bypassing the intestines, because it is unstable in the highly acidic stomach. Because the drug is given parenterally, higher tissue concentrations of penicillin G can be achieved than is possible with phenoxymethylpenicillin. These higher concentrations translate to increased antibacterial activity. | |||
==Category== | |||
[[Penicillins|Penicillinase-resistant penicillins]] | |||
==US Brand Names== | |||
PENICILLIN G SODIUM<sup>®</sup> | |||
==FDA Package Insert== | |||
''' [[Penicillin G sodium description|Description]]''' | |||
'''| [[Penicillin G sodium clinical pharmacology|Clinical Pharmacology]]''' | |||
'''| [[Penicillin G sodium microbiology|Microbiology]]''' | |||
'''| [[Penicillin G sodium indications and usage|Indications and Usage]]''' | |||
'''| [[Penicillin G sodium contraindications|Contraindications]]''' | |||
'''| [[Penicillin G sodium warnings and precautions|Warnings and Precautions]]''' | |||
'''| [[Penicillin G sodium adverse reactions|Adverse Reactions]]''' | |||
'''| [[Penicillin G sodium drug interactions|Drug Interactions]]''' | |||
'''| [[Penicillin G sodium dosage and administration|Dosage and Administration]]''' | |||
'''| [[Penicillin G sodium how supplied|How Supplied]]''' | |||
'''| [[Penicillin G sodium labels and packages|Labels and Packages]]''' | |||
==Mechanism of Action== | |||
Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable resulting in death of the bacterium. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Antibiotics]] | |||
[[Category:Wikinfect]] | |||
Latest revision as of 06:45, 4 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Penicillin G sodium, a water soluble benzylpenicillin,itis bactericidal against penicillin-susceptible microorganisms during the stage of active multiplication. Penicillin G is typically given parenterally, bypassing the intestines, because it is unstable in the highly acidic stomach. Because the drug is given parenterally, higher tissue concentrations of penicillin G can be achieved than is possible with phenoxymethylpenicillin. These higher concentrations translate to increased antibacterial activity.
Category
Penicillinase-resistant penicillins
US Brand Names
PENICILLIN G SODIUM®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable resulting in death of the bacterium.