Posaconazole overdosage: Difference between revisions
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Ahmed Zaghw (talk | contribs) Created page with "__NOTOC__ {{Posaconazole}} {{CMG}}; {{AE}} {{AZ}} ==Overdosage== There is no experience with overdosage of posaconazole delayed-release tablets. During the clinical trials,..." |
Ahmed Zaghw (talk | contribs) |
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==Overdosage== | ==Overdosage== | ||
There is no experience with overdosage of posaconazole delayed-release tablets. | There is '''no experience''' with overdosage of posaconazole delayed-release tablets. | ||
During the clinical trials, some patients received posaconazole oral suspension up to 1600 mg/day with no adverse reactions noted that were different from the lower doses. In addition, accidental overdose was noted in one patient who took 1200 mg BID posaconazole oral suspension for 3 days. No related adverse reactions were noted by the investigator. | During the clinical trials, some patients received posaconazole oral suspension up to 1600 mg/day with '''no adverse reactions''' noted that were different from the lower doses. In addition, accidental overdose was noted in one patient who took 1200 mg BID posaconazole oral suspension for 3 days. No related adverse reactions were noted by the investigator. | ||
Posaconazole is not removed by hemodialysis.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = NOXAFIL (POSACONAZOLE) SUSPENSION NOXAFIL (POSACONAZOLE) TABLET, COATED [MERCK SHARP & DOHME CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b073b082-7b57-4423-8c06-4fd4263d6f84 | publisher = | date = | accessdate = }}</ref> | Posaconazole is '''not removed by hemodialysis'''.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = NOXAFIL (POSACONAZOLE) SUSPENSION NOXAFIL (POSACONAZOLE) TABLET, COATED [MERCK SHARP & DOHME CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b073b082-7b57-4423-8c06-4fd4263d6f84 | publisher = | date = | accessdate = }}</ref> | ||
==References== | ==References== | ||
Latest revision as of 04:15, 9 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Overdosage
There is no experience with overdosage of posaconazole delayed-release tablets.
During the clinical trials, some patients received posaconazole oral suspension up to 1600 mg/day with no adverse reactions noted that were different from the lower doses. In addition, accidental overdose was noted in one patient who took 1200 mg BID posaconazole oral suspension for 3 days. No related adverse reactions were noted by the investigator.
Posaconazole is not removed by hemodialysis.[1]
References
Adapted from the FDA Package Insert.