Praziquantel description: Difference between revisions
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==Description== | ==Description== | ||
BILTRICIDE® (praziquantel) is a trematodicide provided in tablet form for the oral treatment of | BILTRICIDE® (praziquantel) is a trematodicide provided in tablet form for the oral treatment of [[schistosoma]] infections and infections due to liver [[fluke]]. | ||
BILTRICIDE (praziquantel) is 2-(cyclohexylcarbonyl)-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2, 1-a] isoquinolin-4-one with the molecular formula; C19H24N2O2. The structural formula is as follows: | BILTRICIDE (praziquantel) is 2-(cyclohexylcarbonyl)-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2, 1-a] isoquinolin-4-one with the molecular formula; C19H24N2O2. The structural formula is as follows: | ||
Latest revision as of 04:16, 12 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Description
BILTRICIDE® (praziquantel) is a trematodicide provided in tablet form for the oral treatment of schistosoma infections and infections due to liver fluke. BILTRICIDE (praziquantel) is 2-(cyclohexylcarbonyl)-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2, 1-a] isoquinolin-4-one with the molecular formula; C19H24N2O2. The structural formula is as follows:
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Praziquantel is a white to nearly white crystalline powder of bitter taste. The compound is stable under normal conditions and melts at 136-140°C with decomposition. The active substance is hygroscopic. Praziquantel is easily soluble in chloroform and dimethylsulfoxide, soluble in ethanol and very slightly soluble in water. BILTRICIDE tablets contain 600 mg of praziquantel. Inactive ingredients: corn starch, magnesium stearate, microcrystalline cellulose, povidone, sodium lauryl sulfate, polyethylene glycol, titanium dioxide and hypromellose.[1]
References
Adapted from the FDA Package Insert.