Naratriptan description: Difference between revisions
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==Description== | |||
Naratriptan tablets, USP contain naratriptan as the hydrochloride, which is a selective 5-hydroxytryptamine1 receptor subtype agonist. Naratriptan hydrochloride is chemically designated as N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide monohydrochloride, and it has the following structure: | |||
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<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = NARATRIPTAN TABLET, COATED [SANDOZ INC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=39c658d3-5bc8-4f81-9837-1c4edcf1b6c2 | publisher = | date = | accessdate = }}</ref> | The molecular formula is C17H25N3O2S•HCl, representing a molecular weight of 371.93. Naratriptan hydrochloride is an off-white to pale yellow crystalline powder that is sparingly soluble in water. | ||
Each naratriptan tablet for oral administration contains naratriptan hydrochloride equivalent to 1 mg or 2.5 mg of naratriptan, respectively. Each tablet also contains the following inactive ingredients: anhydrous lactose, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, lactose monohydrate, hypromellose, titanium dioxide and triacetin. In addition the 2.5 mg tablet also contains iron oxide yellow and FD&C blue No.2 aluminum lake.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = NARATRIPTAN TABLET, COATED [SANDOZ INC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=39c658d3-5bc8-4f81-9837-1c4edcf1b6c2 | publisher = | date = | accessdate = }}</ref> | |||
==References== | ==References== | ||
Latest revision as of 20:20, 3 February 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Description
Naratriptan tablets, USP contain naratriptan as the hydrochloride, which is a selective 5-hydroxytryptamine1 receptor subtype agonist. Naratriptan hydrochloride is chemically designated as N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide monohydrochloride, and it has the following structure:
 |
The molecular formula is C17H25N3O2S•HCl, representing a molecular weight of 371.93. Naratriptan hydrochloride is an off-white to pale yellow crystalline powder that is sparingly soluble in water.
Each naratriptan tablet for oral administration contains naratriptan hydrochloride equivalent to 1 mg or 2.5 mg of naratriptan, respectively. Each tablet also contains the following inactive ingredients: anhydrous lactose, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, lactose monohydrate, hypromellose, titanium dioxide and triacetin. In addition the 2.5 mg tablet also contains iron oxide yellow and FD&C blue No.2 aluminum lake.[1]
References
Adapted from the FDA Package Insert.