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| __NOTOC__
| | #REDIRECT [[Ezetimibe]] |
| {{Ezetimibe}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Dosage and Administration==
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| ===General Dosing Information===
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| The recommended dose of ZETIA is 10 mg once daily.
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| ZETIA can be administered with or without food.
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| ===Concomitant Lipid-Lowering Therapy===
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| ZETIA may be administered with a [[statin]] (in patients with primary [[hyperlipidemia]]) or with fenofibrate (in patients with mixed [[hyperlipidemia]]) for incremental effect. For convenience, the daily dose of ZETIA may be taken at the same time as the [[statin]] or fenofibrate, according to the dosing recommendations for the respective medications.
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| ===Coadministration with [[bile acid]] Sequestrants===
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| Dosing of ZETIA should occur either ≥2 hours before or ≥4 hours after administration of a [[bile acid]] sequestrant [see Drug Interactions (7.4)].
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| ===Patients with Hepatic Impairment===
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| No dosage adjustment is necessary in patients with mild hepatic impairment [see Warnings and Precautions (5.4)].
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| ===Patients with Renal Impairment===
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| No dosage adjustment is necessary in patients with [[renal impairment]] [see Clinical Pharmacology (12.3)]. When given with simva[[statin]] in patients with moderate to severe renal impairment (estimated glomerular filtration rate <60 mL/min/1.73 m2), doses of simva[[statin]] exceeding 20 mg should be used with caution and close monitoring [seeUse in Specific Populations (8.6)].
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| ===Geriatric Patients===
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| No dosage adjustment is necessary in geriatric patients [see Clinical Pharmacology (12.3)].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = ZETIA (EZETIMIBE) TABLET [MERCK SHARP & DOHME CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=a773b0b2-d31c-4ff4-b9e8-1eb2d3a4d62a | publisher = | date = | accessdate = 11 February 2014 }}</ref>
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| ==References==
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| {{Reflist|2}}
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| [[Category:Hypolipidemic agents]]
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| [[Category:Lactams]]
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| [[Category:Merck]]
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| [[Category:Schering-Plough]]
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| [[Category:Azetidines]]
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| [[Category:Organofluorides]]
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| [[Category:Phenols]]
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| [[Category:Cardiovasuclar Drugs]]
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| [[Category:Drugs]]
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