Amlodipine drug interactions: Difference between revisions

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(Redirected page to Amlodipine#Drug Interactions)
 
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#REDIRECT [[Amlodipine#Drug Interactions]]
 
 
==Drug Interactions==
 
In vitro data indicate that Amlodipine has no effect on the human plasma protein binding of digoxin, phenytoin, warfarin, and indomethacin.
 
===Effect of Other Agents on Amlodipine Besylate Tablets===
 
[[Cimetidine]]: Coadministration of Amlodipine besylate tablets with cimetidine did not alter the pharmacokinetics of Amlodipine.
 
[[Grapefruit juice]]: Coadministration of 240 mL of grapefruit juice with a single oral dose of Amlodipine 10 mg in 20 healthy volunteers had no significant effect on the pharmacokinetics of Amlodipine.
 
[[Antacid]]: Coadministration of the antacid with a single dose of Amlodipine besylate tablets had no significant effect on the pharmacokinetics of Amlodipine.
 
[[Sildenafil]]: A single 100 mg dose of [[sildenafil]] in subjects with essential hypertension had no effect on the pharmacokinetic parameters of [[Amlodipine]]. When Amlodipine besylate tablets and [[sildenafil]] were used in combination, each agent independently exerted its own blood pressure lowering effect.
 
===Effect of Amlodipine Besylate Tablets on Other Agents===
 
[[Atorvastatin]]: Coadministration of multiple 10 mg doses of Amlodipine besylate tablets with 80 mg of atorvastatin resulted in no significant change in the steady state pharmacokinetic parameters of atorvastatin.
 
[[Digoxin]]: Coadministration of Amlodipine besylate tablets with digoxin did not change serum digoxin levels or digoxin renal clearance in normal volunteers.
 
[[Ethanol]] (alcohol): Single and multiple 10 mg doses of Amlodipine besylate tablets had no significant effect on the pharmacokinetics of ethanol.
 
[[Warfarin]]: Coadministration of Amlodipine besylate tablets with warfarin did not change the warfarin prothrombin response time.
 
In clinical trials, Amlodipine besylate tablets have been safely administered with thiazide diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerin, digoxin, warfarin, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs.
 
==Major Interactions==
{{refbegin|3}}
* [[tizanidine]]
* [[Zanaflex]]
{{refend}}
 
==Moderate Interactions==
 
{{refbegin|3}}
* [[A-Hydrocort]]
* [[A-Methapred]]
* [[ABC Plus Senior]]
* [[ABC to Z]]
* [[Abilify]]
* [[Abilify Discmelt]]
* [[acebutolol]]
* [[Acetocot]]
* [[Acetylsalicylic Acid]]
* [[ACTH]]
* [[ACTH Gel]]
* [[ACTH-40 HP]]
* [[ACTH-80]]
* [[Acthar]]
* [[Acthar Gel H.P.]]
* [[Acthrel]]
* [[Actiq]]
* [[Actron]]
* [[Acuprin 81]]
* [[Adbeon]]
* [[ADEKs]]
* [[Adlone-40]]
* [[Adlone-80]]
* [[Adrenocot]]
* [[Adrenocot L.A.]]
* [[Advil]]
* [[Advil Childrens]]
* [[Advil Junior Strength]]
* [[Advil Liquigel]]
* [[Advil Migraine]]
* [[Advil Pediatric]]
* [[Aflaxen]]
* [[Agenerase]]
* [[Akbeta]]
* [[aldesleukin]]
* [[Aleve]]
* [[Aleve Caplet]]
* [[Aleve Easy Open Arthritis]]
* [[Aleve Gelcap]]
* [[Alfenta]]
* [[alfentanil]]
* [[Alka-Mints]]
* [[Alkets]]
* [[Alkums]]
* [[Ami-Natal Plus One Improved]]
* [[amifostine]]
* [[Amigesic]]
* [[Amilac]]
* [[Aminatal Plus]]
* [[Aminatal Plus New Formula]]
* [[Aminatal Plus One]]
* [[Aminate]]
* [[Aminate with 90 mg Iron]]
* [[Aminosyn II 3.5%-Dextrose 25% Electrolytes Ca]]
* [[Aminosyn II 4.25%-Dextrose 20% Electrolyte Ca]]
* [[Aminosyn II 4.25%-Dextrose 25% Electrolyte Ca]]
* [[Aminosyn II with Electrolytes]]
* [[Aminosyn II with Electrolytes Sulfite-Free]]
* [[Aminosyn with Electrolytes]]
* [[Aminosyn with Electrolytes Sulfite-Free]]
* [[Amitone]]
* [[amprenavir]]
* [[Anaflex]]
* [[Anaprox]]
* [[Anaprox-DS]]
* [[Anectine]]
* [[Anectine Flo-Pack]]
* [[Anemagen OB]]
* [[anhydrous calcium iodide]]
* [[Ansaid]]
* [[Antioxid Caplets]]
* [[Antioxidant Formula]]
* [[Antioxidant Ultra Formula]]
* [[Apatate Forte]]
* [[APO-Go]]
* [[APO-Go Pen]]
* [[Apokyn]]
* [[apomorphine]]
* [[AquADEKs]]
* [[AquADEKs Pediatric]]
* [[Arduan]]
* [[Argesic-SA]]
* [[aripiprazole]]
* [[Aristocort]]
* [[Aristocort For Injection]]
* [[Aristocort Forte]]
* [[Aristopak]]
* [[Aristospan Injection]]
* [[Arthritis Pain]]
* [[Arthropan]]
* [[ASA]]
* [[Ascriptin Enteric]]
* [[Aspergum Cherry]]
* [[Aspergum Orginal]]
* [[Aspir-Low]]
* [[aspirin]]
* [[aspirin extended release]]
* [[Aspirin Lite Coat]]
* [[Aspirin Litecoat]]
* [[Aspirin Low Strength]]
* [[Aspirtab]]
* [[Astramorph PF]]
* [[atazanavir]]
* [[atenolol]]
* [[atracurium]]
* [[Avail Calcium Intensive]]
* [[Avinza]]
* [[Azmacort]]
* [[B-Plex Plus Minerals]]
* [[Bacmin]]
* [[Bayer Aspirin]]
* [[Bayer Aspirin Regimen]]
* [[Bayer Aspirin Sugar Free]]
* [[Bayer Aspirin with Calcium]]
* [[Bayer Childrens Aspirin]]
* [[Bayer Low Strength]]
* [[Bayer Plus]]
* [[Bayer Select Backache Pain Formula]]
* [[Becomax Rx]]
* [[Bee-Zee]]
* [[Beelith]]
* [[Berocca Plus]]
* [[Berplex Plus]]
* [[Beta-Phos/AC]]
* [[Betagan]]
* [[Betagan C-Cap]]
* [[Betamed]]
* [[betamethasone]]
* [[betamethasone acet-betamethasone na phosphate]]
* [[betamethasone sodium phosphate]]
* [[Betapace]]
* [[Betapace AF]]
* [[Betapace AF(obsolete)]]
* [[betaxolol]]
* [[betaxolol ophthalmic]]
* [[Betimol]]
* [[Betoptic]]
* [[Betoptic S]]
* [[Biotin Forte with Zinc]]
* [[Bismarex]]
* [[Bismatrol]]
* [[Bismatrol Maximum Strength]]
* [[bismuth subsalicylate]]
* [[bisoprolol]]
* [[Blocadren]]
* [[bosentan]]
* [[Brevibloc]]
* [[Bright Beginnings]]
* [[bromfenac]]
* [[Bubbli-Pred]]
* [[Budeprion SR]]
* [[Budeprion XL]]
* [[budesonide]]
* [[Buffered Aspirin]]
* [[Bufferin]]
* [[Bufferin Arthritis Strength]]
* [[Bufferin Extra Strength]]
* [[Buffex]]
* [[Bugs Bunny Complete]]
* [[Buprenex]]
* [[buprenorphine]]
* [[buPROPion]]
* [[buPROPion 24 hour extended release]]
* [[buPROPion extended release]]
* [[Busodium]]
* [[BuSpar]]
* [[BuSpar Dividose]]
* [[busPIRone]]
* [[butabarbital]]
* [[Butisol Sodium]]
* [[Bystolic]]
* [[cabergoline]]
* [[Cal Oys]]
* [[Cal-Gest]]
* [[Cal-Nate]]
* [[Calafol Rx]]
* [[Calcarb]]
* [[Calcet Plus]]
* [[Calci Mix]]
* [[Calci-Chew]]
* [[CalciFol]]
* [[CalciFolic-D]]
* [[Calcionate]]
* [[Calciquid]]
* [[Calcitab]]
* [[calcium acetate]]
* [[calcium carbonate]]
* [[calcium chloride]]
* [[calcium citrate]]
* [[Calcium Concentrate]]
* [[Calcium Disodium Versenate]]
* [[calcium glubionate]]
* [[calcium gluceptate]]
* [[calcium gluconate]]
* [[calcium glycerophosphate]]
* [[calcium lactate]]
* [[Calcium Liquid Softgel]]
* [[Calcium Oyster]]
* [[Calcium Oyster Shell]]
* [[calcium phosphate]]
* [[tribasic]]
* [[Calphron]]
* [[Caltrate]]
* [[Caltrate 600 Plus]]
* [[Caltrate Plus]]
* [[Caltro]]
* [[carbamazepine]]
* [[carbamazepine extended release]]
* [[Carbatrol]]
* [[Cardizem]]
* [[Cardizem CD]]
* [[Cardizem LA]]
* [[Cardizem Monovial]]
* [[Cardizem SR]]
* [[CareNatal DHA]]
* [[Caromega]]
* [[carteolol]]
* [[carteolol ophthalmic]]
* [[Cartia XT]]
* [[Cartrol]]
* [[carvedilol]]
* [[carvedilol extended release]]
* [[Cataflam]]
* [[Celestone]]
* [[Celestone Phosphate]]
* [[Celestone Soluspan]]
* [[Cell-U-Jec]]
* [[Cenogen Ultra]]
* [[Centavite]]
* [[Central]]
* [[Central-Vite]]
* [[Centrum]]
* [[Centrum Cardio]]
* [[Centrum Jr]]
* [[Centrum Jr with Extra C]]
* [[Centrum Jr with Extra Calcium]]
* [[Centrum Kids Complete Dora the Explorer]]
* [[Centrum Kids Complete SpongeBob SquarePants]]
* [[Centrum Kids Complete Variety]]
* [[Centrum Performance]]
* [[Centrum Silver]]
* [[Centrum Singles]]
* [[Century]]
* [[Century-Vite]]
* [[Cerebyx]]
* [[Cerovite Advanced Formula]]
* [[Cerovite Junior]]
* [[Cerovite Liquid]]
* [[Cerovite Senior]]
* [[Certa-Vite]]
* [[Certa-Vite Senior Plus Lutein]]
* [[Certagen]]
* [[Certagen Senior]]
* [[Certagen Senior with Lutein]]
* [[Certavite]]
* [[CertaVite with Lutein]]
* [[Cezin-S]]
* [[CF Vite]]
* [[Childrens Ibuprofen Berry]]
* [[Childrens Kaopectate]]
* [[choline salicylate]]
* [[Chooz]]
* [[Chromagen OB]]
* [[Circavite T]]
* [[cisatracurium]]
* [[Cit Calcium (obsolete)]]
* [[Citracal]]
* [[Citracal Liquitab]]
* [[Citracal Plus with Magnesium]]
* [[Citracal Prenatal + DHA]]
* [[Citracal Prenatal 90+DHA]]
* [[Citracal Prenatal Rx]]
* [[CitraNatal 90 DHA]]
* [[CitraNatal DHA]]
* [[CitraNatal Rx]]
* [[Clinacort]]
* [[Clinalog]]
* [[Clinimix E Sulfite Free]]
* [[Clinoril]]
* [[Clopine]]
* [[clotrimazole]]
* [[clozapine]]
* [[Clozapine Synthon]]
* [[Clozaril]]
* [[Clusimar]]
* [[codeine]]
* [[codeine phosphate]]
* [[codeine sulfate]]
* [[Colocort]]
* [[Compete]]
* [[Complete A-Z]]
* [[Compound 374]]
* [[Coreg]]
* [[Coreg CR]]
* [[Corgard]]
* [[Corlopam]]
* [[Cort-K]]
* [[Cortastat]]
* [[Cortastat 10]]
* [[Cortastat LA]]
* [[Cortef]]
* [[Cortenema]]
* [[corticorelin]]
* [[corticotropin]]
* [[Cortifoam]]
* [[cortisone]]
* [[Cortone Acetate]]
* [[Cortrosyn]]
* [[Corvite]]
* [[Corvite 150]]
* [[Corvite Free]]
* [[cosyntropin]]
* [[Cotolone]]
* [[Daily Combo]]
* [[Daily Multi-Vitamins with Minerals]]
* [[Daily-Vite Weight Control]]
* [[Dalalone]]
* [[Dalalone D.P.]]
* [[Dalalone L.A.]]
* [[dalfopristin]]
* [[Darvon]]
* [[Darvon-N]]
* [[Daypro]]
* [[Dazidox]]
* [[De-Sone LA]]
* [[Decadron]]
* [[Decadron 5-12 Pak]]
* [[Decadron Phosphate]]
* [[Injectable]]
* [[Decadron-LA]]
* [[Decagen]]
* [[Decaject]]
* [[Decaject L.A.]]
* [[delavirdine]]
* [[Deltasone]]
* [[Demerol HCl]]
* [[Denzapine]]
* [[Dep Medalone 80]]
* [[Depmedalone]]
* [[Depo-Medrol]]
* [[Depo-Predate (obsolete)]]
* [[Depoject-80]]
* [[Deponit]]
* [[Depopred]]
* [[DermaVite]]
* [[desflurane]]
* [[Dexacen-4]]
* [[Dexacort Phosphate in Respihaler]]
* [[Dexacort-LA]]
* [[Dexacorten]]
* [[dexamethasone]]
* [[dexamethasone acetate]]
* [[Dexamethasone Intensol]]
* [[dexamethasone sodium phosphate]]
* [[Dexasone]]
* [[Dexasone LA]]
* [[Dexone]]
* [[Dexone LA]]
* [[Dexpak Jr. Taperpak]]
* [[Dexpak Taperpak]]
* [[Di-Phen]]
* [[Dialyvite 3000]]
* [[Dialyvite 800 with Zinc]]
* [[Dialyvite with Zinc Rx]]
* [[Diatx Zn]]
* [[Diavite Plus]]
* [[Dicarbosil]]
* [[diclofenac]]
* [[diclofenac potassium]]
* [[diclofenac sodium]]
* [[diclofenac sodium extended release]]
* [[Diflucan]]
* [[diflunisal]]
* [[dihydrocodeine]]
* [[Dilacor XR]]
* [[Dilantin]]
* [[Dilantin Infatabs]]
* [[Dilantin Kapseals]]
* [[Dilantin-125]]
* [[Dilaudid]]
* [[Dilaudid-5]]
* [[Dilaudid-HP]]
* [[Diltia XT]]
* [[diltiazem]]
* [[diltiazem 24 hour extended release]]
* [[diltiazem extended release]]
* [[Diltiazem Hydrochloride CD]]
* [[Diltiazem Hydrochloride SR]]
* [[Diltiazem Hydrochloride XR]]
* [[Diltiazem Hydrochloride XT]]
* [[Disalcid]]
* [[Diskets]]
* [[Disney Winnie the Pooh Complete]]
* [[Disney Winnie the Pooh Gummies]]
* [[Disney Winnie the Pooh with Extra C]]
* [[Doans Pills]]
* [[Doans Pills Extra Strength]]
* [[Dolobid]]
* [[Dolomite]]
* [[Dolophine]]
* [[Doloral]]
* [[Doloral Sirop]]
* [[Dopar]]
* [[Doral]]
* [[Dostinex]]
* [[doxacurium]]
* [[Dualvit OB]]
* [[Duet]]
* [[Duet Chewable]]
* [[Duet DHA]]
* [[Duet DHA EC]]
* [[DurAct]]
* [[Duragesic]]
* [[Duragesic-100]]
* [[Duragesic-12]]
* [[Duragesic-25]]
* [[Duragesic-50]]
* [[Duragesic-75]]
* [[Duralone]]
* [[Duramorph PF]]
* [[Easprin]]
* [[EC-Naprosyn]]
* [[Ecee Plus]]
* [[Ecotrin]]
* [[Ecotrin Adult Low Strength]]
* [[Ecotrin Maximum Strength]]
* [[edetate calcium disodium]]
* [[efavirenz]]
* [[Eldercaps]]
* [[Eldertonic]]
* [[Elemental Iron-90]]
* [[Ellis Tonic Sherry]]
* [[elon Matrix 5000 Complete]]
* [[Embrex 600]]
* [[Empirin]]
* [[Encora]]
* [[Endocodone]]
* [[enflurane]]
* [[Entaprin]]
* [[Entercote]]
* [[Entocort]]
* [[Entocort EC]]
* [[Epitol]]
* [[epoprostenol]]
* [[Equetro]]
* [[Equi-Natal Care]]
* [[Equi-Natal M]]
* [[Equi-Natal Plus]]
* [[Equi-Natal Rx]]
* [[Equi-Natal Z]]
* [[Equilet]]
* [[Equinatal 90]]
* [[Eskalith]]
* [[Eskalith-CR]]
* [[esmolol]]
* [[ETH-Oxydose]]
* [[ethotoin]]
* [[Ethrane]]
* [[Ethyol]]
* [[etodolac]]
* [[etodolac extended release]]
* [[etravirine]]
* [[Extra Strength Bayer]]
* [[Extra Strength Mylanta Calci Tabs]]
* [[Fasprin]]
* [[FazaClo]]
* [[Feldene]]
* [[Fem-Natal]]
* [[Femnatal]]
* [[Femtabs]]
* [[fenoldopam]]
* [[fenoprofen]]
* [[fentanyl]]
* [[Fentora]]
* [[Ferrex PC Forte]]
* [[Flintstones Complete]]
* [[Flintstones with Calcium]]
* [[Flo-Pred]]
* [[Flolan]]
* [[Florinef Acetate]]
* [[fluconazole]]
* [[fludrocortisone]]
* [[Fluothane]]
* [[flurbiprofen]]
* [[fluvoxamine]]
* [[fluvoxamine extended release]]
* [[Folbee Plus CZ]]
* [[Folgard OS]]
* [[Folpace Rx]]
* [[Forane]]
* [[Formula B Plus]]
* [[Formula Twenty-One]]
* [[Fortovase]]
* [[fosamprenavir]]
* [[Fosfree]]
* [[fosphenytoin]]
* [[Freamine III with Electrolytes]]
* [[Garfield Complete Vitamins]]
* [[Genacote]]
* [[Generix-T]]
* [[Gennin-FC]]
* [[Genpril]]
* [[Genprin]]
* [[Geodon]]
* [[Geri-Tonic]]
* [[Geritol Complete]]
* [[Geritol Extend]]
* [[Gerivite Liquid]]
* [[Gevrabon]]
* [[Gevratonic]]
* [[Gleevec]]
* [[Glutofac-MX]]
* [[Glutofac-ZX]]
* [[Gold Age Liquid Vitamins and Minerals]]
* [[grepafloxacin]]
* [[Gynovite]]
* [[Hair Booster]]
* [[Haldol]]
* [[Haldol Decanoate]]
* [[Halfprin]]
* [[haloperidol]]
* [[haloperidol decanoate]]
* [[halothane]]
* [[Haltran]]
* [[Hematinic Plus]]
* [[Hemax]]
* [[Hemocyte Plus]]
* [[Hexadrol]]
* [[Hexadrol Phosphate]]
* [[Hi-Nate 90]]
* [[High Potency]]
* [[Hydeltra-T.B.A.]]
* [[Hydeltrasol]]
* [[hydrocortisone]]
* [[hydrocortisone acetate]]
* [[hydrocortisone cypionate]]
* [[hydrocortisone hemisuccinate]]
* [[hydrocortisone sodium phosphate]]
* [[Hydrocortisone Sodium Succinate]]
* [[Hydrocortone]]
* [[Hydrocortone Phosphate]]
* [[Hydromorph Contin]]
* [[hydromorphone]]
* [[hydromorphone extended release]]
* [[Hydrostat IR]]
* [[I-Sense]]
* [[I-Sense OccuShield]]
* [[I-Vite]]
* [[I-Vite Protect]]
* [[Ibu]]
* [[IBU-200]]
* [[Ibu-4]]
* [[Ibu-6]]
* [[Ibu-8]]
* [[Ibu-Tab]]
* [[ibuprofen]]
* [[Ibuprofen PMR]]
* [[ICaps AREDS]]
* [[ICaps MV]]
* [[ICaps Plus]]
* [[Icaps TR]]
* [[ICaps with Lutein and Zeaxan]]
* [[Icar Prenatal]]
* [[Icar Prenatal Chewable Calcium]]
* [[Icare Prenatal Rx]]
* [[iloprost]]
* [[imatinib]]
* [[Inatal Advance]]
* [[Inatal Ultra]]
* [[Inderal]]
* [[Inderal LA]]
* [[Indocin]]
* [[Indocin SR]]
* [[indomethacin]]
* [[indomethacin extended release]]
* [[Infumorph]]
* [[InnoPran XL]]
* [[Intelence]]
* [[Invega]]
* [[Invirase]]
* [[Ionsys]]
* [[isoflurane]]
* [[Istalol]]
* [[itraconazole]]
* [[K-Pek]]
* [[Kadian]]
* [[Kao-Tin Bismuth Subsalicylate Formula]]
* [[Kaopectate]]
* [[Kaopectate Anti-Diarrheal Upset Stomach Reliever]]
* [[Kaopectate Extra Strength]]
* [[Kapectolin (New Formula)]]
* [[Ken-Jec 40]]
* [[Kenaject-40]]
* [[Kenalog-10]]
* [[Kenalog-40]]
* [[Kerlone]]
* [[Ketek]]
* [[Ketek Pak]]
* [[ketoconazole]]
* [[ketoprofen]]
* [[ketoprofen extended release]]
* [[ketorolac]]
* [[Key-Pred]]
* [[Key-Pred SP]]
* [[L-Tonic]]
* [[labetalol]]
* [[Lactocal-F]]
* [[lanreotide]]
* [[lapatinib]]
* [[Lariam]]
* [[Larodopa]]
* [[Leader Naproxen Sodium]]
* [[Levatol]]
* [[Levitra]]
* [[levobetaxolol ophthalmic]]
* [[Levobunolol]]
* [[levobunolol ophthalmic]]
* [[levodopa]]
* [[Lexiva]]
* [[Liquid Pred]]
* [[Litecoat Aspirin]]
* [[lithium]]
* [[lithium carbonate]]
* [[lithium carbonate extended release]]
* [[lithium citrate]]
* [[Lithobid]]
* [[Lithonate]]
* [[Lithotabs]]
* [[Lodine]]
* [[Lodine XL]]
* [[Lopressor]]
* [[Low Dose ASA]]
* [[loxapine]]
* [[Loxitane]]
* [[Loxitane C]]
* [[Loxitane IM]]
* [[Luminal]]
* [[Luvox]]
* [[Luvox CR]]
* [[M-Eslon]]
* [[M-Oxy]]
* [[M-Prednisolone]]
* [[M-Vit]]
* [[M. O. S.]]
* [[Maalox Antacid Barrier]]
* [[Maalox Childrens']]
* [[Maalox Quick Dissolve]]
* [[Maalox Quick Dissolve Extra Strength]]
* [[Maalox Quick Dissolve Maximum Strength]]
* [[Maalox Regular Strength]]
* [[Maalox Total Stomach Relief]]
* [[Mag-SR with Calcium]]
* [[Magan]]
* [[Magna-C-7 Forte]]
* [[MagneBind 400 Rx]]
* [[magnesium salicylate]]
* [[Magonate Tablets]]
* [[maraviroc]]
* [[Marnatal-F Plus]]
* [[Marthritic]]
* [[Materna]]
* [[Maternal 90]]
* [[Maternity]]
* [[Maternity plus Beta Carotene]]
* [[Maternity Vitamin Low Iron]]
* [[Maternity-90]]
* [[Maximum Strength Stress]]
* [[Maxinate]]
* [[meclofenamate]]
* [[Meclomen]]
* [[Med-Jec-40]]
* [[Medicort]]
* [[Medidex]]
* [[Medidex LA]]
* [[Mediplex Ultra]]
* [[Medipred]]
* [[Medralone]]
* [[Medralone 40]]
* [[Medralone 80]]
* [[Medrol]]
* [[Medrol Dosepak]]
* [[mefenamic acid]]
* [[mefloquine]]
* [[meloxicam]]
* [[Menadol]]
* [[Mens Pack]]
* [[meperidine]]
* [[mephenytoin]]
* [[Mesantoin]]
* [[Methacort 40]]
* [[Methacort 80]]
* [[methadone]]
* [[Methadose]]
* [[methdilazine]]
* [[methoxyflurane]]
* [[Methylcotol]]
* [[Methylcotolone]]
* [[Methylpred DP]]
* [[methylprednisolone]]
* [[methylprednisolone acetate]]
* [[methylprednisolone Dose Pack]]
* [[methylprednisolone sodium succinate]]
* [[Meticorten]]
* [[metipranolol ophthalmic]]
* [[metocurine]]
* [[metoprolol]]
* [[metoprolol extended release]]
* [[metoprolol succinate]]
* [[Metoprolol Succinate ER]]
* [[metoprolol tartrate]]
* [[Metubine Iodide]]
* [[Mi-C-T]]
* [[mibefradil]]
* [[miconazole]]
* [[Midol Extended Relief]]
* [[Midol IB]]
* [[Midol Maximum Strength Cramp Formula]]
* [[Mifeprex]]
* [[mifepristone]]
* [[Minitabs]]
* [[Minitran]]
* [[Mission Prenatal]]
* [[Mission Prenatal FA]]
* [[Mission Prenatal HP]]
* [[Mission Prenatal Rx]]
* [[Mivacron]]
* [[mivacurium]]
* [[Mobic]]
* [[Mobidin]]
* [[Monistat I.V.]]
* [[Mono-Gesic]]
* [[morphine]]
* [[morphine 24 hour extended release]]
* [[morphine extended release]]
* [[Morphine IR]]
* [[Morphine LP Epidural]]
* [[morphine preservative-free]]
* [[Morphine Rapi-Ject]]
* [[Morphitec]]
* [[Motrin]]
* [[Motrin Childrens]]
* [[Motrin IB]]
* [[Motrin Infant Drops]]
* [[Motrin Junior Strength]]
* [[Motrin Migraine Pain]]
* [[MS]]
* [[MS Contin]]
* [[MS/S]]
* [[MSIR]]
* [[MST]]
* [[Multi-betic]]
* [[Multi-Day Plus Minerals]]
* [[Multi-Day with Calcium and Extra Iron]]
* [[Multifol Plus]]
* [[Multilex]]
* [[Multilex-T/M+Minerals]]
* [[multivitamin with minerals]]
* [[multivitamin]]
* [[prenatal]]
* [[My-A-Multi]]
* [[Myadec]]
* [[Mycelex Troche]]
* [[Mycobutin]]
* [[Mylanta Child]]
* [[Mynatal]]
* [[Mynatal FC]]
* [[Mynatal Plus]]
* [[Mynatal PN]]
* [[Mynatal PN Forte]]
* [[Mynatal Rx]]
* [[Mynatal Ultracap]]
* [[Mynatal Z]]
* [[Mynate 90 Plus]]
* [[Myvitalife]]
* [[nabumetone]]
* [[nadolol]]
* [[nalbuphine]]
* [[Nalfon]]
* [[Naprelan '375']]
* [[Naprelan '500']]
* [[Naprosyn]]
* [[naproxen]]
* [[naproxen sodium]]
* [[Naproxen Sodium DS]]
* [[naproxen sodium extended release]]
* [[Natacaps]]
* [[Natachew]]
* [[Natafolic-OB]]
* [[Natafolic-PN]]
* [[Natafort]]
* [[NatalCare]]
* [[NatalCare Advanced]]
* [[NatalCare Advanced-RF]]
* [[NatalCare CFE 60]]
* [[Natalcare Pic]]
* [[Natalcare Pic Forte]]
* [[Natalcare Plus]]
* [[Natalcare Rx]]
* [[NatalCare Three]]
* [[Natalcare(obsolete)]]
* [[Natalfirst]]
* [[Natalins]]
* [[Natalins Rx]]
* [[Natarex]]
* [[Natatab CFe]]
* [[Natatab FA]]
* [[Natatab Rx]]
* [[Natelle]]
* [[Natelle C]]
* [[Natelle Plus with DHA]]
* [[Natelle Prefer]]
* [[Natelle-ez]]
* [[nebivolol]]
* [[Neevo]]
* [[nefazodone]]
* [[nelfinavir]]
* [[Neo-Calglucon]]
* [[Neo-Forte]]
* [[NeoProfen]]
* [[Nephro Calci]]
* [[Nestabs]]
* [[Nestabs CBF]]
* [[Nestabs FA]]
* [[Nestabs Rx]]
* [[New Advanced Formula Prenatal Z]]
* [[NIC 750]]
* [[Nicomide]]
* [[Niferex PN Forte]]
* [[Niferex-PN]]
* [[nilotinib]]
* [[Nimbex]]
* [[Nitrek]]
* [[Nitro TD Patch-A]]
* [[Nitro-Bid]]
* [[Nitro-Bid IV]]
* [[Nitro-Dur]]
* [[Nitro-Par]]
* [[Nitro-Time]]
* [[Nitrocot]]
* [[Nitrodisc]]
* [[Nitrogard]]
* [[nitroglycerin]]
* [[Nitroglyn E-R]]
* [[Nitrol]]
* [[Nitrol Appli-Kit]]
* [[Nitrolingual]]
* [[Nitrong]]
* [[Nitroquick]]
* [[Nitrostat]]
* [[Nizoral]]
* [[Norcuron]]
* [[Norlac RX]]
* [[Normodyne]]
* [[Norvir]]
* [[Norvir Soft Gelatin]]
* [[Norwich Aspirin]]
* [[Novanatal]]
* [[NovaStart]]
* [[Novastart (obsolete)]]
* [[Noxafil]]
* [[NTG]]
* [[Nu-Iron V]]
* [[Nubain]]
* [[Nuprin]]
* [[Nuprin Backache Caplet]]
* [[Nuromax]]
* [[NutriNate]]
* [[Nutrispire]]
* [[O-CAL F.A.]]
* [[O-Cal Prenatal]]
* [[O-Cal-FA]]
* [[OB Complete]]
* [[OB Complete with DHA]]
* [[Ob-20]]
* [[Obegyn]]
* [[Obnate 90]]
* [[Obtrex]]
* [[Occuplex]]
* [[octreotide]]
* [[Ocupress]]
* [[Ocuvite]]
* [[Ocuvite Extra]]
* [[Ocuvite Lutein]]
* [[Ocuvite PreserVision]]
* [[olanzapine]]
* [[OMS]]
* [[One Daily with Minerals]]
* [[One Tab Daily with Minerals]]
* [[One-A-Day Max]]
* [[One-A-Day Men 50 Plus]]
* [[One-A-Day WeightSmart]]
* [[One-A-Day Women]]
* [[One-A-Day Women 50 Plus]]
* [[opium]]
* [[Opium Deodorized]]
* [[Opti-Gen]]
* [[Optilets-M-500]]
* [[OptiNate]]
* [[OptiPranolol]]
* [[Optivite P.M.T.]]
* [[Oramorph SR]]
* [[Orapred]]
* [[Orapred ODT]]
* [[Orasone]]
* [[Orudis]]
* [[Orudis KT]]
* [[Oruvail]]
* [[Os-Cal]]
* [[Os-Cal 500]]
* [[Os-Cal Forte]]
* [[Os-Cal Ultra]]
* [[Ostiva]]
* [[oxaprozin]]
* [[oxcarbazepine]]
* [[oxycodone]]
* [[oxycodone extended release]]
* [[OxyContin]]
* [[Oxyfast]]
* [[OxyIR]]
* [[Oysco 500]]
* [[Oyst Cal]]
* [[Oyst Cal 500]]
* [[Oyster]]
* [[Oyster Cal]]
* [[Oyster Cal 500]]
* [[Oyster Calcium]]
* [[Oyster Shell]]
* [[oyster shell calcium]]
* [[Oyster Shell Calcium 500]]
* [[paliperidone]]
* [[Palladone]]
* [[Palladone SR]]
* [[Pan OB Forte]]
* [[pancuronium]]
* [[Par-F]]
* [[Paregoric]]
* [[parenteral nutrition solution w/electrolytes]]
* [[Pavulon]]
* [[Pediacare Fever]]
* [[Pediapred]]
* [[Peganone]]
* [[penbutolol]]
* [[pentazocine]]
* [[Penthrane]]
* [[Peptic Relief]]
* [[Pepto Children's]]
* [[Pepto-Bismol]]
* [[Pepto-Bismol Maximum Strength]]
* [[Percolone]]
* [[phenobarbital]]
* [[phenyl salicylate]]
* [[Phenytek]]
* [[phenytoin]]
* [[phenytoin extended release]]
* [[Phenytoin Sodium]]
* [[Prompt]]
* [[PhosLo]]
* [[PhosLo Gelcap]]
* [[pindolol]]
* [[Pink Bismuth]]
* [[pipecuronium]]
* [[piroxicam]]
* [[PMS Balance]]
* [[Ponstel]]
* [[posaconazole]]
* [[Posicor]]
* [[Posture]]
* [[PP-Cap]]
* [[Pramilet FA]]
* [[Pre-H-Cal]]
* [[Precare]]
* [[Precare Conceive]]
* [[Precare Premier]]
* [[Pred-Ject-50]]
* [[Predacort 50]]
* [[Predacorten]]
* [[Predaject-50]]
* [[Predalone 50]]
* [[Predate-50]]
* [[Predcor]]
* [[Predicort RP]]
* [[Predicort-50]]
* [[Prednicen-M]]
* [[Prednicot]]
* [[prednisolone]]
* [[prednisolone acetate]]
* [[prednisolone sodium phosphate]]
* [[prednisolone tebutate]]
* [[prednisone]]
* [[PreferaOB]]
* [[Prelief]]
* [[Prelone]]
* [[Premesis Rx]]
* [[PrenaFirst]]
* [[Prenatabs CBF]]
* [[Prenatabs FA]]
* [[Prenatabs OBN]]
* [[Prenatabs Rx]]
* [[Prenatal 1 Plus 1]]
* [[Prenatal 1 Plus 1 (Low Iron)]]
* [[Prenatal 19]]
* [[Prenatal AD]]
* [[Prenatal Elite]]
* [[Prenatal H]]
* [[Prenatal Low Iron]]
* [[Prenatal MR 90]]
* [[Prenatal MR 90 Fe]]
* [[Prenatal MTR with Selenium]]
* [[prenatal multivitamin]]
* [[Prenatal Plus]]
* [[Prenatal Plus Iron]]
* [[Prenatal Plus with 27 mg Iron]]
* [[Prenatal Plus with Beta-Carotene]]
* [[Prenatal Rx]]
* [[Prenatal Rx 1]]
* [[Prenatal S]]
* [[Prenatal Z Advanced Formula]]
* [[Prenatal-U]]
* [[Prenate 90]]
* [[Prenate Advance]]
* [[Prenate Advanced Formula]]
* [[Prenate DHA]]
* [[Prenate Elite]]
* [[Prenate GT]]
* [[Prenate Ultra]]
* [[Prenavite]]
* [[Prenavite FC]]
* [[Prenavite PC]]
* [[Prenazyme 1+1]]
* [[Preterna]]
* [[Pri-Cortin 50]]
* [[Priftin]]
* [[PrimaCare]]
* [[PrimaCare Advantage]]
* [[Primacare One]]
* [[Primethasone]]
* [[Procalamine]]
* [[Procycle Multi Vitamin with Minerals]]
* [[Proleukin]]
* [[propoxyphene]]
* [[propoxyphene hydrochloride]]
* [[propoxyphene napsylate]]
* [[propranolol]]
* [[propranolol extended release]]
* [[Prosight]]
* [[prostacyclin]]
* [[Protegra Softgel]]
* [[Pulmicort Flexhaler]]
* [[Pulmicort Nebuamp]]
* [[Pulmicort Respules]]
* [[Pulmicort Turbuhaler]]
* [[Q-Profen]]
* [[quazepam]]
* [[Quelicin Chloride]]
* [[quetiapine]]
* [[quetiapine extended release]]
* [[rapacuronium]]
* [[Raplon]]
* [[Raxar]]
* [[Re Dualvit F]]
* [[Re Dualvit Plus]]
* [[RE Fac-X]]
* [[Relafen]]
* [[Remodulin]]
* [[RenaPlex]]
* [[Renatabs with Iron]]
* [[Renax]]
* [[Renax 5.5]]
* [[Reocyte Plus]]
* [[Rescriptor]]
* [[Rescudose]]
* [[Resource Optisource]]
* [[Revatio]]
* [[Rexolate]]
* [[Reyataz]]
* [[Rezulin]]
* [[Ridactate]]
* [[rifabutin]]
* [[Rifadin]]
* [[Rifadin IV]]
* [[rifampin]]
* [[rifapentine]]
* [[Rimactane]]
* [[Risperdal]]
* [[Risperdal Consta]]
* [[Risperdal M-Tab]]
* [[risperidone]]
* [[ritonavir]]
* [[RMS]]
* [[rocuronium]]
* [[Rolaids Sodium Free]]
* [[Rolaids Soft Chew]]
* [[Roxanol]]
* [[Roxanol 100]]
* [[Roxanol-T]]
* [[Roxicodone]]
* [[Roxicodone Intensol]]
* [[RU-486]]
* [[Ru-Lets M 500]]
* [[Rufen]]
* [[Saleto-200]]
* [[Saleto-400]]
* [[Saleto-600]]
* [[Saleto-800]]
* [[Salflex]]
* [[salsalate]]
* [[Salsitab]]
* [[Sandostatin]]
* [[Sandostatin LAR Depot]]
* [[saquinavir]]
* [[saquinavir mesylate]]
* [[secobarbital]]
* [[Seconal Sodium]]
* [[Sectral]]
* [[Select-OB]]
* [[Selestoject]]
* [[Selzentry]]
* [[Senetonic]]
* [[Seroquel]]
* [[Seroquel XR]]
* [[Serzone]]
* [[Sesame St. Vitamins Complete]]
* [[sevoflurane]]
* [[Siderol]]
* [[sildenafil]]
* [[Sloprin]]
* [[sodium salicylate]]
* [[sodium thiosalicylate]]
* [[Sojourn]]
* [[Solfoton]]
* [[Solu-Cortef]]
* [[Solu-Medrol]]
* [[Solurex]]
* [[Solurex LA]]
* [[Somatuline Depot]]
* [[Sorine]]
* [[sotalol]]
* [[Sotalol Hydrochloride AF]]
* [[Sotalol Hydrochloride AF(obsolete)]]
* [[SourceCF Chewables]]
* [[SourceCF Multivitamins with A, B, D, E & K plus Zinc]]
* [[SourceCF Pediatric Drops]]
* [[SourceCF Softgels]]
* [[Sporanox]]
* [[SSS]]
* [[St. Joseph Aspirin]]
* [[St. Joseph Aspirin Adult Chewable]]
* [[St. Joseph Aspirin Adult EC]]
* [[Stanback Analgesic]]
* [[Statex]]
* [[Sterapred]]
* [[Sterapred DS]]
* [[Stress 600 with Zinc]]
* [[Stress Formula with Zinc]]
* [[Stress Maximum Strength]]
* [[StressTabs with Zinc]]
* [[Strongstart]]
* [[Strovite]]
* [[Strovite Advance]]
* [[Strovite Forte]]
* [[Strovite Plus]]
* [[Stuart Prenatal with Beta Carotene]]
* [[Stuartnatal Plus]]
* [[Stuartnatal Plus 3]]
* [[Sublimaze]]
* [[Subutex]]
* [[succinylcholine]]
* [[Succinylcholine Chloride]]
* [[Sufenta]]
* [[sufentanil]]
* [[sulindac]]
* [[Super Calcium]]
* [[Super High Vitamins and Minerals]]
* [[Support]]
* [[Support 500]]
* [[Suprane]]
* [[Surbex-750 with Zinc]]
* [[Surpass]]
* [[Surpass Extra Strength]]
* [[Sustiva]]
* [[T-Gran plus Minerals]]
* [[T-Lite]]
* [[Tab-A-Vite Maximum]]
* [[Tab-A-Vite WeightSlim]]
* [[Tab-A-Vite Womens Formula]]
* [[TAC 3]]
* [[Tacaryl]]
* [[Talwin Lactate]]
* [[Tandem DHA]]
* [[Tandem OB]]
* [[Tandem Plus]]
* [[Tasigna]]
* [[Taztia XT]]
* [[Tegretol]]
* [[Tegretol XR]]
* [[telithromycin]]
* [[Telzir]]
* [[Tenormin]]
* [[Ternamar]]
* [[Terrell]]
* [[Thera Hematinic]]
* [[Thera M]]
* [[Thera-M]]
* [[Thera-Vite M]]
* [[Theragener-H]]
* [[Theragener-M]]
* [[Theragran-M]]
* [[Therapeutic-M]]
* [[Therapy Bayer]]
* [[Theravim M]]
* [[Therems M]]
* [[Therobec Plus]]
* [[Tiazac]]
* [[timolol]]
* [[timolol hemihydrate ophthalmic]]
* [[timolol ophthalmic]]
* [[timolol ophthalmic long-acting]]
* [[Timoptic Ocudose]]
* [[Timoptic Ocumeter]]
* [[Timoptic Ocumeter Plus]]
* [[Timoptic-XE]]
* [[Titralac]]
* [[Tolectin]]
* [[Tolectin 600]]
* [[Tolectin DS]]
* [[tolmetin]]
* [[Toprol-XL]]
* [[Toradol]]
* [[Toradol IM]]
* [[Toradol IV/IM]]
* [[Tracleer]]
* [[Tracrium]]
* [[Tramacort-D]]
* [[Trandate]]
* [[Travasol with Electrolytes]]
* [[Travasol with Electrolytes Dual Chamber]]
* [[treprostinil]]
* [[Tri-Buffered Aspirin]]
* [[Triam-A]]
* [[Triam-Forte]]
* [[triamcinolone]]
* [[triamcinolone acetonide]]
* [[triamcinolone diacetate]]
* [[triamcinolone hexacetonide]]
* [[Triamcot]]
* [[Triamonide 40]]
* [[tricalcium phosphate]]
* [[TriCare]]
* [[Tridil]]
* [[Trileptal]]
* [[Trilog]]
* [[Trilone]]
* [[Trinate]]
* [[Tristoject]]
* [[troglitazone]]
* [[tubocurarine]]
* [[Tums]]
* [[Tums 500]]
* [[Tums E-X]]
* [[Tums Extra Strength]]
* [[Tums Ultra]]
* [[Tusal]]
* [[Tykerb]]
* [[U-Tri-Lone]]
* [[Udamin]]
* [[Udamin SP]]
* [[Ultane]]
* [[Ultane P.E.N.]]
* [[Ultra Mylanta Calci Tabs]]
* [[Ultra NatalCare]]
* [[Ultra-Natal]]
* [[Uni-Fac ZX]]
* [[Uni-Thera M with Beta Carotene]]
* [[Unicap M]]
* [[Unicap Senior]]
* [[Unicap T]]
* [[Unicomplex M]]
* [[Uprima]]
* [[V-C Forte]]
* [[vardenafil]]
* [[vecuronium]]
* [[Vecuronium Bromide]]
* [[Ventavis]]
* [[Vernate]]
* [[Vernate Advanced]]
* [[Verotin-BY]]
* [[Verotin-GR]]
* [[VFEND]]
* [[Vi-Zac]]
* [[Viactiv Calcium Flavor Glides]]
* [[Viactiv Multi-Vitamin]]
* [[Viactiv Multi-Vitamin Flavor Glides]]
* [[Viactiv Soft Calcium Chews]]
* [[Viagra]]
* [[Vica-Forte]]
* [[Vicap Forte]]
* [[Vicon Forte]]
* [[Vicon Plus]]
* [[Vicon-C]]
* [[Vigortol Liquid]]
* [[Vinatal 600]]
* [[Vinatal Forte]]
* [[Vinate 90]]
* [[Vinate Advanced (New Formula)]]
* [[Vinate AZ]]
* [[Vinate AZ Extra]]
* [[Vinate Calcium]]
* [[Vinate Good Start]]
* [[Vinate GT]]
* [[Vinate II (New Formula)]]
* [[Vinate M]]
* [[Vinate Ultra]]
* [[Viogen-C]]
* [[Viracept]]
* [[Visken]]
* [[Vita S Forte]]
* [[Vita Zx]]
* [[Vita-Dec]]
* [[Vita-Min Rx]]
* [[Vita-Zinc]]
* [[Vitacon Forte]]
* [[Vitafol]]
* [[Vitafol PN]]
* [[Vitafol-OB]]
* [[Vitafol-OB+DHA]]
* [[Vital-D]]
* [[Vitalize Plus]]
* [[Vitamax]]
* [[Vitamed Prenatal Formula]]
* [[Vitaphil]]
* [[Vitaplex Plus]]
* [[Vitelle Nestabs OTC]]
* [[Voltaren]]
* [[Voltaren-XR]]
* [[voriconazole]]
* [[Vynatal 1 Plus 1]]
* [[Vynatal F.A.]]
* [[Wellbutrin]]
* [[Wellbutrin SR]]
* [[Wellbutrin XL]]
* [[Womens Pack]]
* [[YSP Aspirin]]
* [[Z-Bec]]
* [[Z-Gen]]
* [[Zaponex]]
* [[ZE-Plus]]
* [[Zebeta]]
* [[Zemuron]]
* [[Zenate]]
* [[Zenate Advanced Formula]]
* [[Zenate Prenatal]]
* [[Zero-Order Release]]
* [[Zincvit]]
* [[ziprasidone]]
* [[Zitamin]]
* [[Zodeac-100]]
* [[Zorprin]]
* [[Zyban]]
* [[Zyban Advantage Pack]]
* [[Zyprexa]]
* [[Zyprexa Zydis]]
{{refend}}
 
==Minor Interactions==
{{refbegin|3}}
* [[Accupril]]
* [[Aceon]]
* [[Alphagan]]
* [[Alphagan P]]
* [[Altace]]
* [[apraclonidine ophthalmic]]
* [[Aquacot]]
* [[Aquatensen]]
* [[Aquazide H]]
* [[armodafinil]]
* [[Atapryl]]
* [[Azilect]]
* [[benazepril]]
* [[bendroflumethiazide]]
* [[benzthiazide]]
* [[brimonidine ophthalmic]]
* [[Capoten]]
* [[captopril]]
* [[Carbex]]
* [[Carozide]]
* [[chlorothiazide]]
* [[chlorthalidone]]
* [[Cialis]]
* [[Diaqua]]
* [[Diucardin]]
* [[Diurese]]
* [[Diuril]]
* [[Diuril Sodium]]
* [[Eldepryl]]
* [[Emsam]]
* [[enalapril]]
* [[enalaprilat]]
* [[Enduron]]
* [[Esidrix]]
* [[Exna]]
* [[Ezide]]
* [[fluoxetine]]
* [[fluoxetine extended release]]
* [[fosinopril]]
* [[furazolidone]]
* [[Furoxone]]
* [[HCTZ]]
* [[Hydro Par]]
* [[hydrochlorothiazide]]
* [[Hydrodiuril]]
* [[hydroflumethiazide]]
* [[Hygroton]]
* [[indapamide]]
* [[Iopidine]]
* [[isocarboxazid]]
* [[Jumex]]
* [[linezolid]]
* [[lisinopril]]
* [[Loqua]]
* [[Lotensin]]
* [[Lozol]]
* [[Marplan]]
* [[Matulane]]
* [[Mavik]]
* [[Metahydrin]]
* [[methyclothiazide]]
* [[metolazone]]
* [[Microzide]]
* [[modafinil]]
* [[moexipril]]
* [[Monopril]]
* [[Mykrox]]
* [[Naqua]]
* [[Nardil]]
* [[Naturetin-10]]
* [[Naturetin-5]]
* [[Nuvigil]]
* [[Oretic]]
* [[Parnate]]
* [[perindopril]]
* [[phenelzine]]
* [[polythiazide]]
* [[Prinivil]]
* [[procarbazine]]
* [[Provigil]]
* [[Prozac]]
* [[Prozac Weekly]]
* [[quinapril]]
* [[ramipril]]
* [[Rapiflux]]
* [[rasagiline]]
* [[Renese]]
* [[Saluron]]
* [[Sarafem]]
* [[selegiline]]
* [[Selgene]]
* [[tadalafil]]
* [[Thalitone]]
* [[trandolapril]]
* [[tranylcypromine]]
* [[trichlormethiazide]]
* [[Univasc]]
* [[Vasotec]]
* [[verteporfin]]
* [[Visudyne]]
* [[Zaroxolyn]]
* [[Zelapar]]
* [[Zestril]]
* [[zileuton]]
* [[zileuton extended release]]
* [[Zyflo]]
* [[Zyflo CR]]
* [[Zyvox]]
{{refend}}
 
 
 
 
{{FDA}}
 
 
 
 
 


[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]
[[Category:Drugs]]

Latest revision as of 15:41, 21 July 2014