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| __NOTOC__
| | #REDIRECT [[Atenolol#Overdosage]] |
| {{Atenolol}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Overdosage==
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| Overdosage with TENORMIN has been reported with patients surviving acute doses as high as 5 g. One death was reported in a man who may have taken as much as 10 g acutely. | |
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| The predominant symptoms reported following TENORMIN overdose are lethargy, disorder of respiratory drive, wheezing, sinus pause and bradycardia. Additionally, common effects associated with overdosage of any beta-adrenergic blocking agent and which might also be expected in TENORMIN overdose are congestive heart failure, hypotension, bronchospasm and/or hypoglycemia.
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| Treatment of overdose should be directed to the removal of any unabsorbed drug by induced emesis, gastric lavage, or administration of activated charcoal. TENORMIN can be removed from the general circulation by hemodialysis. Other treatment modalities should be employed at the physician's discretion and may include:
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| '''BRADYCARDIA''': [[Atropine]] intravenously. If there is no response to vagal blockade, give isoproterenol cautiously. In refractory cases, a transvenous cardiac pacemaker may be indicated.
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| '''HEART BLOCK '''(SECOND OR THIRD DEGREE): [[Isoproterenol]] or transvenous cardiac pacemaker.
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| '''CARDIAC FAILURE''': Digitalize the patient and administer a diuretic. Glucagon has been reported to be useful.
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| '''HYPOTENSION''': Vasopressors such as [[dopamine]] or [[norepinephrine]] (levarterenol). Monitor blood pressure continuously.
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| '''BRONCHOSPASM''': A beta2 stimulant such as [[isoproterenol]] or [[terbutaline]] and/or aminophylline.
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| '''HYPOGLYCEMIA''': Intravenous glucose.
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| Based on the severity of symptoms, management may require intensive support care and facilities for applying cardiac and respiratory support.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = TENORMIN (ATENOLOL) TABLET [ASTRAZENECA PHARMACEUTICALS LP] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=fcfc9676-4edc-460e-6199-8161b824908f | publisher = | date = | accessdate = 5 February 2014 }}</ref>
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| ==References==
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| {{Reflist|2}}
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| [[Category:Beta blockers]] | | [[Category:Beta blockers]] |
| [[Category:Cardiovascular Drugs]] | | [[Category:Cardiovascular Drugs]] |
| [[Category:Drugs]] | | [[Category:Drugs]] |
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