Amiodarone overdose: Difference between revisions

Latest revision as of 19:07, 21 July 2014

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+#REDIRECT [[AmiodaroneI#Overdosage]]
-There have been cases, some fatal, of Amiodarone overdose.
-In addition to general supportive measures, the patient's cardiac rhythm and blood pressure should be monitored, and if bradycardia ensues, a β-adrenergic agonist or a pacemaker may be used. Hypotension with inadequate tissue perfusion should be treated with positive inotropic and/or vasopressor agents. '''Neither Amiodarone nor its metabolite is dialyzable'''.
-The acute oral LD<sub>50</sub> of Amiodarone HCl in mice and rats is greater than 3,000 mg/kg.