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| __NOTOC__
| | #REDIRECT [[Moexipril#Adult Indications and Dosage]] |
| {{Moexipril}}
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| {{CMG}}; {{AE}} {{AM}}
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| ==Dosage and Administration==
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| ====Hypertension====
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| The recommended initial dose of moexipril hydrochloride in patients not receiving diuretics is 7.5 mg, one hour prior to meals, once daily. Dosage should be adjusted according to blood pressure response. The antihypertensive effect of moexipril hydrochloride may diminish towards the end of the dosing interval. Blood pressure should, therefore, be measured just prior to dosing to determine whether satisfactory blood pressure control is obtained. If control is not adequate, increased dose or divided dosing can be tried. The recommended dose range is 7.5 to 30 mg daily, administered in one or two divided doses one hour before meals. Total daily doses above 60 mg a day have not been studied in hypertensive patients.
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| In patients who are currently being treated with a [[diuretic]], symptomatic [[hypotension]] may occasionally occur following the initial dose of moexipril hydrochloride. The diuretic should, if possible, be discontinued for 2 to 3 days before therapy with moexipril hydrochloride is begun, to reduce the likelihood of [[hypotension]]. If the patient's blood pressure is not controlled with moexipril hydrochloride alone, [[diuretic]] therapy may then be reinstituted. If diuretic therapy cannot be discontinued, an initial dose of 3.75 mg of moexipril hydrochloride should be used with medical supervision until blood pressure has stabilized.
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| ====Dosage Adjustment in Renal Impairment====
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| For patients with a [[creatinine clearance]] ≤40 mL/min/1.73 m2, an initial dose of 3.75 mg once daily should be given cautiously. Doses may be titrated upward to a maximum daily dose of 15 mg.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = MOEXIPRIL HYDROCHLORIDE TABLET [APOTEX CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d18108f5-98ca-1220-d145-bcf4e71ceaee | publisher = | date = | accessdate = }}</ref>
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| ==References==
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| {{Reflist}}
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| {{FDA}}
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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