|
|
| (One intermediate revision by one other user not shown) |
| Line 1: |
Line 1: |
| __NOTOC__
| | #REDIRECT [[Dipyridamole#Adverse Reactions]] |
| {{Dipyridamole}}
| |
| {{CMG}}; {{AE}} {{SS}}
| |
| | |
| ==Adverse Reactions==
| |
| | |
| Adverse reactions at therapeutic doses are usually minimal and transient. On long-term use of PERSANTINE tablets initial side effects usually disappear. The following reactions in Table 1 were reported in two heart valve replacement trials comparing PERSANTINE tablets and [[warfarin]] therapy to either [[warfarin]] alone or [[warfarin]] and placebo:
| |
| {|
| |
| |-
| |
| |[[File:Dipyridamole02.jpg|thumb|800px]]
| |
| |-
| |
| |}
| |
| Other reactions from uncontrolled studies include [[diarrhea]], [[vomiting]], flushing and [[pruritus]]. In addition, [[angina]] pectoris has been reported rarely and there have been rare reports of liver dysfunction. On those uncommon occasions when adverse reactions have been persistent or intolerable, they have ceased on withdrawal of the medication.
| |
| | |
| When Persantine® (dipyridamole USP) tablets were administered concomitantly with [[warfarin]], bleeding was no greater in frequency or severity than that observed when [[warfarin]] was administered alone. In rare cases, increased bleeding during or after surgery has been observed.
| |
| | |
| In post-marketing reporting experience, there have been rare reports of [[hypersensitivity]] reactions (such as [[rash]], urticaria, severe bronchospasm, and [[angioedema]]), [[larynx edema]], fatigue, [[malaise]], [[myalgia]], [[arthritis]], [[nausea]], [[dyspepsia]], [[paresthesia]], [[hepatitis]], [[thrombocytopenia]], [[alopecia]], [[cholelithiasis]], [[hypotension]], [[palpitation]], and [[tachycardia]].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = PERSANTINE (DIPYRIDAMOLE) TABLET, COATED [BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=ca68879c-0214-4d7c-93b0-bdaf8ef23f8e | publisher = | date = | accessdate = 7 February 2014 }}</ref>
| |
| | |
| ==References==
| |
| | |
| {{Reflist|2}}
| |
| | |
| [[Category:Antiplatelet drugs]]
| |
| [[Category:Cardiovascular Drugs]]
| |
| [[Category:Drugs]]
| |
| {{WikiDoc Help Menu}}
| |
| {{WikiDoc Sources}}
| |