|
|
| (2 intermediate revisions by one other user not shown) |
| Line 1: |
Line 1: |
| __NOTOC__
| | #REDIRECT [[Methyldopa#Adverse Reactions]] |
| {{Methyldopa}}
| |
| {{CMG}}; {{AE}} {{AK}}
| |
| | |
| ==ADVERSE REACTIONS==
| |
| | |
| Sedation, usually transient, may occur during the initial period of therapy or whenever the dose is increased. [[Headache]], [[asthenia]], or weakness may be noted as early and transient symptoms. However, significant adverse effects due to methyldopa have been infrequent and this agent usually is well tolerated.
| |
| | |
| The following adverse reactions have been reported and, within each category, are listed in order of decreasing severity.
| |
| | |
| '''Cardiovascular:''' Aggravation of [[angina pectoris]], [[congestive heart failure]], prolonged carotid sinus hypersensitivity, [[orthostatic hypotension]] (decrease daily dosage), [[edema ]]or weight gain, [[bradycardia]].
| |
| | |
| '''Digestive:''' [[Pancreatitis]], [[colitis]], [[vomiting]], [[diarrhea]], [[sialadenitis]], [[sore ]]or black tongue, [[nausea]], [[constipation]], [[distension]], flatus, dryness of mouth.
| |
| | |
| '''Endocrine:''' [[Hyperprolactinemia]].
| |
| | |
| '''Hematologic:''' [[Bone marrow depression]], [[leukopenia]], [[granulocytopenia]], [[thrombocytopenia]], [[hemolytic anemia]]; positive tests for antinuclear antibody, LE cells, and [[rheumatoid factor]], positive [[Coombs test]].
| |
| | |
| '''Hepatic:''' Liver disorders including [[hepatitis]], [[jaundice]], abnormal liver function tests (see [[Methyldopa tablet|WARNINGS]]).
| |
| '''Hypersensitivity:''' [[Myocarditis]], [[pericarditis]], [[vasculitis]], lupus-like syndrome, drug-related fever, [[eosinophilia]].
| |
| | |
| '''Nervous System/Psychiatric:''' [[Parkinsonism]], [[Bell's palsy]], decreased mental acuity, involuntary choreoathetotic movements, symptoms of cerebrovascular insufficiency, psychic disturbances including [[nightmares ]]and reversible mild [[psychoses ]]or [[depression]], [[headache]], [[sedation]], [[asthenia ]]or [[weakness]], [[dizziness]], light-headedness, [[paresthesias]].
| |
| | |
| '''Metabolic:''' Rise in [[BUN]].
| |
| | |
| '''Musculoskeletal:''' [[Arthralgia]], with or without joint swelling; [[myalgia]].
| |
| | |
| '''Respiratory:''' Nasal [[stuffiness]].
| |
| | |
| '''Skin:''' [[Toxic epidermal necrolysis]], [[rash]].
| |
| | |
| '''Urogenital:''' [[Amenorrhea]], breast enlargement, [[gynecomastia]], [[lactation]], [[impotence]], decreased [[libido]].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = METHYLDOPA TABLET [CARDINAL HEALTH] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d87d63fd-48f7-4130-af03-5e263c338fe4 | publisher = | date = | accessdate = 10 March 2014 }}</ref>
| |
| | |
| | |
| | |
| ==References==
| |
| | |
| {{Reflist|2}}
| |
| | |
| [[Category:Cardiovascular Drugs]]
| |
| [[Category:Drugs]]
| |