Bivalirudin mechanism of action: Difference between revisions

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Created page with "{{SI}} {{CMG}} ==Overview== ==Mechanism of action== 1) Specific and reversible direct thrombin inhibitor 2) Binds to the catalytic and anionic sites of both circulating and clo..."
 
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←Redirected page to Bivalirudin#Pharmacology
 
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{{SI}}
#REDIRECT [[Bivalirudin#Pharmacology]]
{{CMG}}
 
==Overview==
==Mechanism of action==
1) Specific and reversible direct thrombin inhibitor
 
2) Binds to the catalytic and anionic sites of both circulating and clot-bound thrombin.
 
3) Catalytic binding site occupation functionally inhibits coagulant effects by preventing thrombin-mediated cleavage of fibrinogen to fibrin monomers, and activation of factors V, VIII, and XIII. \
 
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