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| __NOTOC__
| | #REDIRECT [[Ticagrelor#Contraindications]] |
| {{Ticagrelor}}
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| {{CMG}}; {{AE}} {{JH}}
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| ==Contraindication==
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| ====History of Intracranial Hemorrhage====
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| BRILINTA is contraindicated in patients with a history of [[intracranial hemorrhage]] (ICH) because of a high risk of recurrent ICH in this population [see Clinical Studies (14)].
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| ====Active Bleeding====
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| BRILINTA is contraindicated in patients with active pathological bleeding such as peptic ulcer or [[intracranial hemorrhage]] [see Warnings and Precautions (5.1) and Adverse Reactions (6.1)].
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| ====Severe Hepatic Impairment====
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| BRILINTA is contraindicated in patients with severe hepatic impairment because of a probable increase in exposure, and it has not been studied in these patients. Severe hepatic impairment increases the risk of bleeding because of reduced synthesis of coagulation proteins [see Clinical Pharmacology (12.3)].
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| ====Hypersensitivity====
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| BRILINTA is contraindicated in patients with hypersensitivity (e.g. [[angioedema]]) to ticagrelor or any component of the product [see Adverse Reactions (6.2)].
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| ==References==
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| {{Reflist|2}}
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| {{Antithrombotics}}
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| [[Category:ADP receptor inhibitors]]
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| [[Category:Triazolopyrimidines]]
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| [[Category:Organofluorides]]
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| [[Category:Alcohols]]
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| [[Category:AstraZeneca]]
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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