Prasugrel dosage and administration: Difference between revisions

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(Created page with "__NOTOC__ {{Prasugrel}} {{CMG}}; {{AE}} {{SS}} ==Dosage And Administration== Initiate Effient treatment as a single 60-mg oral loading dose and then continue at 10-mg orally...")
 
 
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{{Prasugrel}}
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==Dosage And Administration==
 
Initiate Effient treatment as a single 60-mg oral loading dose and then continue at 10-mg orally once daily. Patients taking Effient should also take [[aspirin]] (75-mg to 325-mg) daily [see Drug Interactions (7.3) and Clinical Pharmacology (12.3)]. Effient may be administered with or without food [see Clinical Pharmacology (12.3) and Clinical Studies (14)].
 
===Dosing in Low Weight Patients===
 
Compared to patients weighing ≥60 kg, patients weighing <60 kg have an increased exposure to the active metabolite of prasugrel and an increased risk of bleeding on a 10-mg once daily maintenance dose. Consider lowering the maintenance dose to 5-mg in patients <60 kg. The effectiveness and safety of the 5-mg dose have not been prospectively studied<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5fe9c118-c44b-48d7-a142-9668ae3df0c6 | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5fe9c118-c44b-48d7-a142-9668ae3df0c6 | publisher =  | date =  | accessdate = 6 February 2014 }}</ref>
 
==References==
 
{{Reflist|2}}
 
[[Category:Antiplatelet drugs]]
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]
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Latest revision as of 02:51, 22 July 2014