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| __NOTOC__
| | #redirect [[Lovastatin#Adult Indications and Dosage]] |
| {{Lovastatin}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Dosage and Administration==
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| [[Hyperlipidemia]] (Heterozygous Familial and Nonfamilial) and Mixed [[Dyslipidemia]] (Fredrickson Types IIa and IIb) | |
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| The recommended dosing range is 20-60 mg/day, in single doses taken in the evening at bedtime.
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| ===Elderly Patients===
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| The usual recommended starting dose in elderly patients (age≥65 years) is 20 mg once a day given in the evening at bedtime. Higher doses should be used only after careful consideration of the potential risks and benefits [see Use in Specific Populations (8.5) and Warnings and Precautions, Skeletal Muscle Effects (5.1)].
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| ===Co-administration with Other Drugs===
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| Patients Taking [[Danazol]], [[Diltiazem]], [[Dronedarone]], or [[Verapamil]]
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| The dose of Altoprev should not exceed 20 mg/day [see Warnings and Precautions, Skeletal Muscle Effects (5.1)].
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| Patients Taking [[Amiodarone]]
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| The dose of Altoprev should not exceed 40 mg/day. [see Warnings and Precautions, Skeletal Muscle Effects (5.1) and Drug Interactions (7.6)].
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| ===Dosage in Patients With Renal Impairment===
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| In patients with severe [[renal impairment]] (creatinine clearance <30 mL/min), dosage increases above 20 mg/day should only be considered if the expected benefit exceeds the increased risk of [[myopathy]]/[[rhabdomyolysis]]. [see Warnings and Precautions, Skeletal Muscle Effects (5.1) and Clinical Pharmacology, Pharmacokinetics (12.3)].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = ALTOPREV (LOVASTATIN) TABLET, EXTENDED RELEASE [SHIONOGI INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=e8b6ccc2-e6e7-45fd-ab66-c312bcbe2b01 | publisher = | date = | accessdate = 13 February 2014 }}</ref>
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| ==References==
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| {{Reflist|2}}
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| {{Statins}}
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| [[Category:Statins]]
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| [[Category:Carboxylate esters]]
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| [[Category:Lactones]]
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| [[Category:Cardiovascular Drug]]
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| [[Category:Drug]]
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