High density lipoprotein epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
For 2009–2010, 21.3% of adults aged 20 and over had low HDL cholesterol (less than 40 mg/dL). The percentage of adults with low HDL cholesterol was higher for men (31.4%) than for women (11.9%). Percentages among men were also higher than those among women of the same racial and ethnic group. For men, the percentage with low HDL cholesterol was lower among non-Hispanic black men than non-Hispanic white or Hispanic men. No racial or ethnic differences were found among women in the percentage with low HDL cholesterol.<ref name=NCHS>Margaret D. Carroll, M.S.P.H.; Brian K. Kit, M.D., M.P.H.; and David A. Lacher, M.D., M.Ed. Total and High-density Lipoprotein Cholesterol in Adults: National Health and Nutrition Examination Survey, 2009–2010. April 2012. [http://www.cdc.gov/nchs/data/databriefs/db92.htm CDC.gov]</ref>
For 2009–2010, 21.3% of adults aged 20 and over had low HDL cholesterol (less than 40 mg/dL) in the United States. The percentage of adults with low HDL cholesterol was higher for men (31.4%) than for women (11.9%). Percentages among men were also higher than those among women of the same racial and ethnic group. For men, the percentage with low HDL cholesterol was lower among non-Hispanic black men than non-Hispanic white or Hispanic men. No racial or ethnic differences were found among women in the percentage with low HDL cholesterol.<ref name=NCHS>Margaret D. Carroll, M.S.P.H.; Brian K. Kit, M.D., M.P.H.; and David A. Lacher, M.D., M.Ed. Total and High-density Lipoprotein Cholesterol in Adults: National Health and Nutrition Examination Survey, 2009–2010. April 2012. [http://www.cdc.gov/nchs/data/databriefs/db92.htm CDC.gov]</ref>


==Low HDL Epidemiology and Demographics==
==Low HDL Epidemiology and Demographics==
===Prevalence===
===Prevalence===
*In 2009–2010, 21.3% of adults aged 20 years and over had low HDL cholesterol level (less than 40 mg/dL) in the United States.
*In 2009–2010, 21.3% of adults aged 20 years and over had low HDL cholesterol level (less than 40 mg/dL) in the United States.
*A large survey has been set out to determine the prevalence of low HDL in 11 European countries.  The study population included 8545 patients under the treatment for [[dyslipidemia]].  This treatment appeared to exert little or no effect on the prevalence of low HDL-cholesterol, which was slightly higher than that measured in the overall population.  Low HDL-cholesterol was present in 33% of men and 40% of women, with very low HDL-cholesterol present in 14% (both genders combined).  The prevalence was found much higher in diabetic patients compared to general population. <ref>{{Cite web  | last =  | first =  | title = Epidemiology of low HDL-cholesterol: results of studies and surveys | url = http://eurheartjsupp.oxfordjournals.org/content/8/suppl_F/F17.full?sid=5e22a755-aec9-4a06-9593-b5a3f02e1864 | publisher =  | date =  | accessdate = 20 September 2013 }}</ref>  
 
* In Europe, the prevalence of low HDL-cholesterol was estimated to be approximately 33% among men and 40% among women, with very low HDL-cholesterol present in 14% (both genders combined).  A higher prevalence was reported among diabetic patients compared to the general population.<ref>{{Cite web  | last =  | first =  | title = Epidemiology of low HDL-cholesterol: results of studies and surveys | url = http://eurheartjsupp.oxfordjournals.org/content/8/suppl_F/F17.full?sid=5e22a755-aec9-4a06-9593-b5a3f02e1864 | publisher =  | date =  | accessdate = 20 September 2013 }}</ref>


===Gender===
===Gender===
*The percentage of adults with low HDL cholesterol as shown below was higher for men (31.4%) than for women (11.9%).  Percentages among men were also higher than those among women of the same racial and ethnic group.<ref name="pmid22617230">{{cite journal| author=Carroll MD, Kit BK, Lacher DA| title=Total and high-density lipoprotein cholesterol in adults: National Health and Nutrition Examination Survey, 2009-2010. | journal=NCHS Data Brief | year= 2012 | volume=  | issue= 92 | pages= 1-8 | pmid=22617230 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22617230  }} </ref>  
* During 2009–2010, approximately 31% of men and 12% of women had low levels of HDL cholesterol.  Percentages among men were also higher than those among women of the same racial and ethnic group.<ref name="pmid22617230">{{cite journal| author=Carroll MD, Kit BK, Lacher DA| title=Total and high-density lipoprotein cholesterol in adults: National Health and Nutrition Examination Survey, 2009-2010. | journal=NCHS Data Brief | year= 2012 | volume=  | issue= 92 | pages= 1-8 | pmid=22617230 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22617230  }} </ref>
 
Shown below are diagrams depicting the prevalence of low HDL cholesterol by age group and sex in the United States between 2009 and 2010 (Source:CDC.gov).
 
[[File:Prevalence of low HDL cholesterol by age group and sex in the United States between 2009 and 2010.PNG|center|Prevalence of low HDL cholesterol by age group and sex in the United States between 2009 and 2010]]
 
* In Europe, the prevalence of low HDL-cholesterol was estimated to be approximately 33% among men and 40% among women.<ref>{{Cite web  | last =  | first =  | title = Epidemiology of low HDL-cholesterol: results of studies and surveys | url = http://eurheartjsupp.oxfordjournals.org/content/8/suppl_F/F17.full?sid=5e22a755-aec9-4a06-9593-b5a3f02e1864 | publisher =  | date =  | accessdate = 20 September 2013 }}</ref>


===Race===
===Race===
*For men, the percentage with low HDL cholesterol was lower among non-Hispanic black men than non-Hispanic white or Hispanic men.<ref name="pmid22617230">{{cite journal| author=Carroll MD, Kit BK, Lacher DA| title=Total and high-density lipoprotein cholesterol in adults: National Health and Nutrition Examination Survey, 2009-2010. | journal=NCHS Data Brief | year= 2012 | volume=  | issue= 92 | pages= 1-8 | pmid=22617230 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22617230  }} </ref>  
*For men, the prevalence of low HDL cholesterol was lower among non-Hispanic black men than non-Hispanic white or Hispanic men.<ref name="pmid22617230">{{cite journal| author=Carroll MD, Kit BK, Lacher DA| title=Total and high-density lipoprotein cholesterol in adults: National Health and Nutrition Examination Survey, 2009-2010. | journal=NCHS Data Brief | year= 2012 | volume=  | issue= 92 | pages= 1-8 | pmid=22617230 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22617230  }} </ref>  


*No racial or ethnic differences were found among women in the percentage with low HDL cholesterol.<ref name="pmid22617230">{{cite journal| author=Carroll MD, Kit BK, Lacher DA| title=Total and high-density lipoprotein cholesterol in adults: National Health and Nutrition Examination Survey, 2009-2010. | journal=NCHS Data Brief | year= 2012 | volume=  | issue= 92 | pages= 1-8 | pmid=22617230 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22617230  }} </ref>  
*No racial or ethnic differences were reported among women with low HDL cholesterol.<ref name="pmid22617230">{{cite journal| author=Carroll MD, Kit BK, Lacher DA| title=Total and high-density lipoprotein cholesterol in adults: National Health and Nutrition Examination Survey, 2009-2010. | journal=NCHS Data Brief | year= 2012 | volume=  | issue= 92 | pages= 1-8 | pmid=22617230 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22617230  }} </ref>  
 
Shown below is a diagram depicting the prevalence of low HDL cholesterol by ethinicity in the United States between 2009 and 2010 (Source:CDC.gov).


[[File:HDL epidemiology in the United States between 2009 and 2010.PNG|center|500px]]
[[File:HDL epidemiology in the United States between 2009 and 2010.PNG|center|500px]]


==High HDL Epidemiology and Demographics==
===Age===
* Exact data regarding the prevalence of high HDL serum level is not well documented.  On the other hand, the inverse relationship between the HDL level and the risk of cardiovascular disease has been documented by the [[Framingham Heart Study]]; for a given level of LDL the risk of heart disease increases 10-fold as the HDL varies from high to low.<ref name="pmid21296318">{{cite journal| author=Rahilly-Tierney CR, Spiro A, Vokonas P, Gaziano JM| title=Relation between high-density lipoprotein cholesterol and survival to age 85 years in men (from the VA normative aging study). | journal=Am J Cardiol | year= 2011 | volume= 107 | issue= 8 | pages= 1173-7 | pmid=21296318 | doi=10.1016/j.amjcard.2010.12.015 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21296318  }} </ref>
The percentage of adults with low HDL cholesterol declines with age for men and women.
 
* In 1980, a large cross section study that included 4756 white males and females aged 20 to 59 years was conducted to assess the association of different factors to the HDL level.  The study population was further stratified according to age, sex, and gonadal hormone use.  Higher levels of HDL have been associated with female gender, moderate alcohol consumption and exercise.<ref name="pmid7418140">{{cite journal| author=Heiss G, Johnson NJ, Reiland S, Davis CE, Tyroler HA| title=The epidemiology of plasma high-density lipoprotein cholesterol levels. The Lipid Research Clinics Program Prevalence Study. Summary. | journal=Circulation | year= 1980 | volume= 62 | issue= 4 Pt 2 | pages= IV116-36 | pmid=7418140 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7418140  }} </ref>
 
* Another study that compared the demographic and behavioral correlates of HDL-cholesterol between Northern Italy and the US indicated that physical activity is positively associated with HDL mean levels.  The study has found that education level is positively associated with HDL levels only in the American sample.<ref name="pmid1521969">{{cite journal| author=Ferrario M, Cesana GC, Heiss G, Linn SA, Mocarelli P, Tyroler HA| title=Demographic and behavioural correlates of high density lipoprotein cholesterol. An international comparison between northern Italy and the United States. | journal=Int J Epidemiol | year= 1992 | volume= 21 | issue= 4 | pages= 665-75 | pmid=1521969 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1521969  }} </ref>


==References==
==References==

Latest revision as of 21:24, 9 October 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]; Rim Halaby, M.D. [3]

Overview

For 2009–2010, 21.3% of adults aged 20 and over had low HDL cholesterol (less than 40 mg/dL) in the United States. The percentage of adults with low HDL cholesterol was higher for men (31.4%) than for women (11.9%). Percentages among men were also higher than those among women of the same racial and ethnic group. For men, the percentage with low HDL cholesterol was lower among non-Hispanic black men than non-Hispanic white or Hispanic men. No racial or ethnic differences were found among women in the percentage with low HDL cholesterol.[1]

Low HDL Epidemiology and Demographics

Prevalence

  • In 2009–2010, 21.3% of adults aged 20 years and over had low HDL cholesterol level (less than 40 mg/dL) in the United States.
  • In Europe, the prevalence of low HDL-cholesterol was estimated to be approximately 33% among men and 40% among women, with very low HDL-cholesterol present in 14% (both genders combined). A higher prevalence was reported among diabetic patients compared to the general population.[2]

Gender

  • During 2009–2010, approximately 31% of men and 12% of women had low levels of HDL cholesterol. Percentages among men were also higher than those among women of the same racial and ethnic group.[3]

Shown below are diagrams depicting the prevalence of low HDL cholesterol by age group and sex in the United States between 2009 and 2010 (Source:CDC.gov).

Prevalence of low HDL cholesterol by age group and sex in the United States between 2009 and 2010
Prevalence of low HDL cholesterol by age group and sex in the United States between 2009 and 2010
  • In Europe, the prevalence of low HDL-cholesterol was estimated to be approximately 33% among men and 40% among women.[4]

Race

  • For men, the prevalence of low HDL cholesterol was lower among non-Hispanic black men than non-Hispanic white or Hispanic men.[3]
  • No racial or ethnic differences were reported among women with low HDL cholesterol.[3]

Shown below is a diagram depicting the prevalence of low HDL cholesterol by ethinicity in the United States between 2009 and 2010 (Source:CDC.gov).

Age

The percentage of adults with low HDL cholesterol declines with age for men and women.

References

  1. Margaret D. Carroll, M.S.P.H.; Brian K. Kit, M.D., M.P.H.; and David A. Lacher, M.D., M.Ed. Total and High-density Lipoprotein Cholesterol in Adults: National Health and Nutrition Examination Survey, 2009–2010. April 2012. CDC.gov
  2. "Epidemiology of low HDL-cholesterol: results of studies and surveys". Retrieved 20 September 2013.
  3. 3.0 3.1 3.2 Carroll MD, Kit BK, Lacher DA (2012). "Total and high-density lipoprotein cholesterol in adults: National Health and Nutrition Examination Survey, 2009-2010". NCHS Data Brief (92): 1–8. PMID 22617230.
  4. "Epidemiology of low HDL-cholesterol: results of studies and surveys". Retrieved 20 September 2013.


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