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__NOTOC__
__NOTOC__
{{Dilated cardiomyopathy}}
{{Dilated cardiomyopathy}}
 
{{CMG}}; {{AE}} Sachin Shah, M.D. {{Ochuko}}
{{CMG}}; '''Associate Editor-in-Chief:''' Sachin Shah, M.D.


==Overview==
==Overview==
There are many causes of dilated cardiomyopathy. The most common cause is [[idiopathic]] in 50% of cases. The next most common cause is [[myocarditis]]  which is responsible for 10% of cases. The high percentage of idiopathic dilated cardiomyopathy may be related to the difficulty in diagnosing viral myocarditis.  Other common causes include [[substance abuse]], connective tissue disease, [[pregnancy]], [[medications]], nutritional deficiencies, infiltrative diseases and [[toxin]]s.  There are varying degrees of severity of the disease.  Some forms are reversible and some are irreversible; some patients may be completely asymptomatic and some may require cardiac transplantation.
There are many causes of [[dilated cardiomyopathy]]. The most common cause is [[idiopathic]] in 50% of cases. The next most common cause is [[myocarditis]]  which is responsible for 10% of cases. The high percentage of idiopathic [[dilated cardiomyopathy]] may be related to the difficulty in diagnosing viral [[myocarditis]].  Other common causes include [[substance abuse]], connective tissue disease, [[pregnancy]], [[medications]], [[nutritional deficiencies]], infiltrative diseases and [[toxin]]s.  There are varying degrees of severity of the disease.  Some forms are reversible and some are irreversible; some patients may be completely [[asymptomatic]] and some may require [[Heart transplantation|cardiac transplantation]].


==Causes==
==Causes==
There are several recorded causes for [[dilated cardiomyopathy]]. <ref> Felker GM, Thompson RE, et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med 2000 Apr 13;342(14):1077-84.</ref><ref name="pmid27339497">Japp AG, Gulati A, Cook SA, Cowie MR, Prasad SK (2016) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=27339497 The Diagnosis and Evaluation of Dilated Cardiomyopathy.] ''J Am Coll Cardiol'' 67 (25):2996-3010. [http://dx.doi.org/10.1016/j.jacc.2016.03.590 DOI:10.1016/j.jacc.2016.03.590] PMID: [https://pubmed.gov/27339497 27339497]</ref><ref name="pmid31693481">{{cite journal| author=Baris L, Cornette J, Johnson MR, Sliwa K, Roos-Hesselink JW| title=Peripartum cardiomyopathy: disease or syndrome? | journal=Heart | year= 2019 | volume= 105 | issue= 5 | pages= 357-362 | pmid=31693481 | doi=10.1136/heartjnl-2018-314252 | pmc=6613742 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31693481  }}</ref><ref name="pmid28190577">{{cite journal| author=Weintraub RG, Semsarian C, Macdonald P| title=Dilated cardiomyopathy. | journal=Lancet | year= 2017 | volume= 390 | issue= 10092 | pages= 400-414 | pmid=28190577 | doi=10.1016/S0140-6736(16)31713-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28190577  }}</ref><ref name="pmid27634407">{{cite journal| author=Favalli V, Serio A, Grasso M, Arbustini E| title=Genetic causes of dilated cardiomyopathy. | journal=Heart | year= 2016 | volume= 102 | issue= 24 | pages= 2004-2014 | pmid=27634407 | doi=10.1136/heartjnl-2015-308190 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27634407  }}</ref>
===Life Threatening Causes===
===Life Threatening Causes===
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
*[[Carbon monoxide poisoning]]


===Common Causes===
===Common Causes===
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*[[HIV infection]]
*[[HIV infection]]
*[[Hypertensive heart disease]]
*[[Hypertensive heart disease]]
*[[Idiopathic]] <ref> Felker GM, Thompson RE, et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med 2000 Apr 13;342(14):1077-84.</ref>
*[[Idiopathic]]  
*[[Ischemic cardiomyopathy]]
*[[Ischemic cardiomyopathy]]
*[[Myocarditis]]
*[[Myocarditis]]
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{|style="width:80%; height:100px" border="1"
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Alstrom syndrome]], [[amyloidosis]], [[Carvajal-Huerta syndrome]], [[coronary artery disease]], [[endocardial fibroelastosis]], [[eosinophilic cardiomyopathy]], [[hemochromatosis]], [[myocarditis|hypersensitivity myocarditis]], [[hypertension]], [[hypertensive heart disease]], [[ischemic cardiomyopathy]], [[ischemic heart disease]], [[Kawasaki disease]], [[myocarditis]], [[myxoma]], [[peripartum cardiomyopathy]], [[rheumatic fever]], [[Salih myopathy]], [[tachycardia]], [[dilated cardiomyopathy|x-linked dilated cardiomyopathy]]
|-
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Beryllium]], [[carbon monoxide poisoning]], [[cobalt]], [[heavy metals]], [[lead]], [[mercury]], [[toxins]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"|[[Carvajal-Huerta syndrome]], [[dermatomyositis]], familial cutaneous collagenoma, [[scleroderma]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Adriamycin]], [[amphetamines]], [[anthracyclines]], [[antiretroviral drugs]], [[bleomycin]], [[certolizumab pegol]],[[chemotherapeutic agents]], [[chloroquine]], [[clozapine]], [[cyclophosphamide ]], [[didanosine]], [[disopyramide]], [[doxorubicin]], [[epirubicin]], [[idarubicin]], [[imatinib mesylate]], [[lithium ]], [[methysergide]], [[mitoxantrone]], [[paracetamol]], peplomycin, [[phenothiazines]], [[tacrolimus]], [[trastuzumab]], [[zalcitabine]], [[zidovudine]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Acromegaly]], [[amyloidosis]], [[Cushing's syndrome]], [[diabetes mellitus]], [[hemochromatosis]], [[hyperparathyroidism]], [[hypoparathyroidism]], [[hypothyroidism]], [[myxedema]], [[pheochromocytoma]], [[pituitary tumor]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Environmental'''
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Heat stroke]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Hemochromatosis]], [[sarcoidosis]], [[Whipple's disease]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Alstrom syndrome]], [[Barth syndrome]], [[Becker muscular dystrophy]], [[desmin-related myopathy]], [[Duchenne's muscular dystrophy]], [[Emery-Dreifuss muscular dystrophy, X-linked]], [[Erb dystrophy]], [[Fabry's disease]], familial cutaneous collagenoma, [[Friedreich's ataxia]], [[hemochromatosis]], [[Laing distal myopathy]], [[limb girdle muscular dystrophy]], [[McLeod neuroacanthocytosis syndrome]], [[McLeod phenotype]], [[Naxos disease]], [[Salih myopathy]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Hemochromatosis]], [[McLeod neuroacanthocytosis syndrome]], [[McLeod phenotype]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Radiation]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Adenovirus]], [[brucellosis]], [[Chagas disease]], [[Coxsackie virus]], [[cryptococcosis]], [[cytomegalovirus]], [[diphtheria]], [[echovirus]], [[Epstein-Barr virus]], [[hepatitis]], [[histoplasmosis]], [[HIV infection]], [[influenza virus]], [[leptospirosis]], [[Loa loa]], [[Lyme disease]], [[myocarditis]], [[parvovirus]], [[psittacosis]], [[rheumatic fever]], [[schistosomiasis]], [[syphillis]], [[toxoplasmosis]], [[trichinosis]], [[trypanosomiasis]], [[typhoid fever]], [[varicella]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Becker muscular dystrophy]], [[desmin-related myopathy]], [[Duchenne's muscular dystrophy]], [[Emery-Dreifuss muscular dystrophy, X-linked]], [[Erb dystrophy]], [[hemochromatosis]], [[Laing distal myopathy]], [[limb girdle muscular dystrophy]], [[myotonic dystrophy]], [[rheumatoid arthritis]], [[Salih myopathy]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Friedreich's ataxia]], [[giant cell arteritis]], [[Refsum's disease]], [[sleep apnea]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Beriberi]], [[carnitine]], [[Fabry's disease]], [[glycogenosis type 2b]], [[hypocalcemia]], [[hypophosphatemia]], [[isobutyryl-CoA dehydrogenase deficiency]], [[niacin]], [[nutritional deficiencies]], [[pellagra]], [[Refsum's disease]], [[selenium deficiency]], [[thiamine]], [[triosephosphate isomerase deficiency]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Childbirth]], [[pregnancy]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"|[[Myxoma]], [[pheochromocytoma]], [[pituitary tumor]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Giant cell arteritis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
| '''Overdose/Toxicity'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"|[[Alcohol abuse]], [[cocaine]], [[ethanol]], [[substance abuse]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
Line 115: Line 119:
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"|[[Sarcoidosis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| '''Renal/Electrolyte'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"|[[Uremia]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Amyloidosis]], [[connective tissue disease]], [[dermatomyositis]], [[giant cell arteritis]], [[rheumatic fever]], [[rheumatoid arthritis]], [[sarcoidosis]], [[scleroderma]], [[serum sickness]], [[systemic lupus erythematosis]], [[transplant rejection]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
Line 131: Line 135:
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Electric shock]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
Line 139: Line 143:
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Heat stroke]], [[hypothermia ]], [[idiopathic]]
|-
|-
|}
|}


===Causes in Alphabetical Order===
===Causes in Alphabetical Order===
 
{{col-begin|width=80%}}
{{col-break|width=33%}}
*[[Acromegaly]]
*[[Adenovirus]]
*[[Adriamycin]]
*[[Alcohol abuse]]
*[[Alström syndrome]]
*[[Alström syndrome]]
*[[Amphetamines]]
*[[Amyloidosis]]
*[[Anthracyclines]]
*[[Antiretroviral drugs]]
*[[Antiretroviral drugs]]
*[[Barth syndrome]]
*[[Barth syndrome]]
*[[Becker muscular dystrophy]]
*[[Becker muscular dystrophy]]
*Carvajal-Huerta syndrome
*[[Beriberi]]
*[[Beryllium]]
*[[Bleomycin]]
*[[Brucellosis]]
*[[Carbon monoxide poisoning]]
*[[Carnitine]]
*[[Carvajal-Huerta syndrome]]
*[[Certolizumab pegol]]
*[[Certolizumab pegol]]
*[[Chagas disease]]
*[[Chagas disease]]
*[[Chemotherapeutic agents]]
*[[Childbirth]]
*[[Chloroquine]]
*[[Clozapine]]
*[[Cobalt]]
*[[Cocaine]]
*[[Connective tissue disease]]
*[[Connective tissue disease]]
*[[Cushing syndrome]]
*[[Coronary artery disease]]
*Desmin-related myopathy
*[[Coxsackie virus]]
*[[Cryptococcosis]]
*[[Cushing's syndrome]]
*[[Cyclophosphamide ]]
*[[Cytomegalovirus]]
*[[Dermatomyositis]]
*[[Desmin-related myopathy]]
*[[Diabetes mellitus]]
*[[Didanosine]]
*[[Diphtheria]]
*[[Disopyramide]]
*[[Disopyramide]]
*[[Drugs]] (such as the chemotherapeutic agent doxarubicin)
*[[Doxorubicin]]
*[[Duchenne muscular dystrophy]]
*[[Duchenne's muscular dystrophy]]
*Dystrophia myotonica type 2
*[[Echovirus]]
*[[Electric shock]]
*[[Emery-Dreifuss muscular dystrophy, X-linked]]
*[[Emery-Dreifuss muscular dystrophy, X-linked]]
*[[Endocardial fibroelastosis]]
*[[Endocardial fibroelastosis]]
*[[Epirubicin]]
*[[Epirubicin]]
{{col-break|width=33%}}
*[[Epstein-Barr virus]]
*[[Erb dystrophy]]
*[[Ethanol]]
*[[Ethanol]]
*[[Fabry's disease]]
*[[Fabry's disease]]
*Familial cutaneous collagenoma
*[[Friedreich's ataxia]]
*[[Giant cell arteritis]]
*[[Glycogenosis type 2b]]
*[[Glycogenosis type 2b]]
*[[Heat stroke]]
*[[Heavy metals]]
*[[Hemochromatosis]]
*[[Hepatitis]]
*[[Histoplasmosis]]
*[[HIV infection]]
*[[HIV infection]]
*[[Hyperparathyroidism]]
*[[myocarditis|Hypersensitivity myocarditis]]
*[[Hypertension]]
*[[Hypertensive heart disease]]
*[[Hypertensive heart disease]]
*[[Hypocalcemia]]
*[[Hypoparathyroidism]]
*[[Hypophosphatemia]]
*[[Hypothermia ]]
*[[Hypothyroidism]]
*[[Idarubicin]]
*[[Idiopathic]]
*[[Imatinib mesylate]]
*[[Imatinib mesylate]]
*Infiltrative disease
*[[Influenza virus]]
*[[Ischaemic heart disease]]
*[[Ischemic heart disease]]
*[[Ischemic cardiomyopathy]]
*[[Ischemic cardiomyopathy]]
*[[Isobutyryl-CoA dehydrogenase deficiency]]
*[[Isobutyryl-CoA dehydrogenase deficiency]]
*[[Kawasaki disease]]
*[[Laing distal myopathy]]
*[[Laing distal myopathy]]
*[[Lead]]
*[[Leptospirosis]]
*[[Limb girdle muscular dystrophy]]
*[[Lithium ]]
*[[Loa loa]]
*[[Lyme disease]]
*[[McLeod neuroacanthocytosis syndrome]]
*[[McLeod neuroacanthocytosis syndrome]]
*[[McLeod phenotype]]
*[[McLeod phenotype]]
*Monosomy 1p36 syndrome
*[[Mercury]]
*[[Myocarditis]]-second most common and it accounts for roughly 10% of cases.
*[[Methysergide]]
*[[Mitoxantrone]]
*[[Myocarditis]]
*[[Myotonic dystrophy]]
{{col-break|width=33%}}
*[[Myxedema]]
*[[Myxoma]]
*[[Naxos disease]]
*[[Naxos disease]]
*[[Niacin]]
*[[Nutritional deficiencies]]
*[[Paracetamol]]
*[[Parvovirus]]
*[[Pellagra]]
*Peplomycin
*[[Peripartum cardiomyopathy]]
*[[Peripartum cardiomyopathy]]
*Peripartum heart failure
*[[Phenothiazines]]
*[[Pheochromocytoma]]
*[[Pituitary tumor]]
*[[Pregnancy]]
*[[Psittacosis]]
*[[Radiation]]
*[[Refsum's disease]]
*[[Rheumatic fever]]
*[[Rheumatoid arthritis]]
*[[Salih myopathy]]
*[[Salih myopathy]]
*[[Sarcoidosis]]
*[[Scleroderma]]
*[[Selenium deficiency]]
*[[Selenium deficiency]]
*[[Substance abuse]] (i.e. [[alcohol]] abuse or [[cocaine]] abuse)
*[[Serum sickness]]
*[[Toxins]] (such as [[cobalt]], [[lead]] or [[beryllium]])
*[[Schistosomiasis]]
*[[Sleep apnea]]
*[[Substance abuse]]
*[[Syphilis]]
*[[Systemic lupus erythematosis]]  
*[[Tachycardia]]
*[[Tacrolimus]]
*[[Thiamine]]  
*[[Toxins]]  
*[[Toxoplasmosis]]
*[[Transplant rejection]]  
*[[Trastuzumab]]
*[[Trastuzumab]]
*X-linked dilated cardiomyopathy
*[[Trichinosis]]
*[[Triosephosphate isomerase deficiency]]
*[[Trypanosomiasis]]
*[[Typhoid fever]]
*[[Uremia]]
*[[Varicella]]
*[[Whipple's disease]]
*[[dilated cardiomyopathy|X-linked dilated cardiomyopathy]]
*[[Zalcitabine]]
*[[Zidovudine]]
{{col-end}}


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Needs causes]]
 
[[Category:Crowdiagnosis]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Cardiomyopathy]]
[[Category:Cardiomyopathy]]

Latest revision as of 16:34, 30 December 2019

Dilated cardiomyopathy Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sachin Shah, M.D. Ogheneochuko Ajari, MB.BS, MS [2]

Overview

There are many causes of dilated cardiomyopathy. The most common cause is idiopathic in 50% of cases. The next most common cause is myocarditis which is responsible for 10% of cases. The high percentage of idiopathic dilated cardiomyopathy may be related to the difficulty in diagnosing viral myocarditis. Other common causes include substance abuse, connective tissue disease, pregnancy, medications, nutritional deficiencies, infiltrative diseases and toxins. There are varying degrees of severity of the disease. Some forms are reversible and some are irreversible; some patients may be completely asymptomatic and some may require cardiac transplantation.

Causes

There are several recorded causes for dilated cardiomyopathy. [1][2][3][4][5]

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Causes by Organ System

Cardiovascular Alstrom syndrome, amyloidosis, Carvajal-Huerta syndrome, coronary artery disease, endocardial fibroelastosis, eosinophilic cardiomyopathy, hemochromatosis, hypersensitivity myocarditis, hypertension, hypertensive heart disease, ischemic cardiomyopathy, ischemic heart disease, Kawasaki disease, myocarditis, myxoma, peripartum cardiomyopathy, rheumatic fever, Salih myopathy, tachycardia, x-linked dilated cardiomyopathy
Chemical/Poisoning Beryllium, carbon monoxide poisoning, cobalt, heavy metals, lead, mercury, toxins
Dental No underlying causes
Dermatologic Carvajal-Huerta syndrome, dermatomyositis, familial cutaneous collagenoma, scleroderma
Drug Side Effect Adriamycin, amphetamines, anthracyclines, antiretroviral drugs, bleomycin, certolizumab pegol,chemotherapeutic agents, chloroquine, clozapine, cyclophosphamide , didanosine, disopyramide, doxorubicin, epirubicin, idarubicin, imatinib mesylate, lithium , methysergide, mitoxantrone, paracetamol, peplomycin, phenothiazines, tacrolimus, trastuzumab, zalcitabine, zidovudine
Ear Nose Throat No underlying causes
Endocrine Acromegaly, amyloidosis, Cushing's syndrome, diabetes mellitus, hemochromatosis, hyperparathyroidism, hypoparathyroidism, hypothyroidism, myxedema, pheochromocytoma, pituitary tumor
Environmental Heat stroke
Gastroenterologic Hemochromatosis, sarcoidosis, Whipple's disease
Genetic Alstrom syndrome, Barth syndrome, Becker muscular dystrophy, desmin-related myopathy, Duchenne's muscular dystrophy, Emery-Dreifuss muscular dystrophy, X-linked, Erb dystrophy, Fabry's disease, familial cutaneous collagenoma, Friedreich's ataxia, hemochromatosis, Laing distal myopathy, limb girdle muscular dystrophy, McLeod neuroacanthocytosis syndrome, McLeod phenotype, Naxos disease, Salih myopathy
Hematologic Hemochromatosis, McLeod neuroacanthocytosis syndrome, McLeod phenotype
Iatrogenic Radiation
Infectious Disease Adenovirus, brucellosis, Chagas disease, Coxsackie virus, cryptococcosis, cytomegalovirus, diphtheria, echovirus, Epstein-Barr virus, hepatitis, histoplasmosis, HIV infection, influenza virus, leptospirosis, Loa loa, Lyme disease, myocarditis, parvovirus, psittacosis, rheumatic fever, schistosomiasis, syphillis, toxoplasmosis, trichinosis, trypanosomiasis, typhoid fever, varicella
Musculoskeletal/Orthopedic Becker muscular dystrophy, desmin-related myopathy, Duchenne's muscular dystrophy, Emery-Dreifuss muscular dystrophy, X-linked, Erb dystrophy, hemochromatosis, Laing distal myopathy, limb girdle muscular dystrophy, myotonic dystrophy, rheumatoid arthritis, Salih myopathy
Neurologic Friedreich's ataxia, giant cell arteritis, Refsum's disease, sleep apnea
Nutritional/Metabolic Beriberi, carnitine, Fabry's disease, glycogenosis type 2b, hypocalcemia, hypophosphatemia, isobutyryl-CoA dehydrogenase deficiency, niacin, nutritional deficiencies, pellagra, Refsum's disease, selenium deficiency, thiamine, triosephosphate isomerase deficiency
Obstetric/Gynecologic Childbirth, pregnancy
Oncologic Myxoma, pheochromocytoma, pituitary tumor
Ophthalmologic Giant cell arteritis
Overdose/Toxicity Alcohol abuse, cocaine, ethanol, substance abuse
Psychiatric No underlying causes
Pulmonary Sarcoidosis
Renal/Electrolyte Uremia
Rheumatology/Immunology/Allergy Amyloidosis, connective tissue disease, dermatomyositis, giant cell arteritis, rheumatic fever, rheumatoid arthritis, sarcoidosis, scleroderma, serum sickness, systemic lupus erythematosis, transplant rejection
Sexual No underlying causes
Trauma Electric shock
Urologic No underlying causes
Miscellaneous Heat stroke, hypothermia , idiopathic

Causes in Alphabetical Order

References

  1. ↑ Felker GM, Thompson RE, et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med 2000 Apr 13;342(14):1077-84.
  2. ↑ Japp AG, Gulati A, Cook SA, Cowie MR, Prasad SK (2016) The Diagnosis and Evaluation of Dilated Cardiomyopathy. J Am Coll Cardiol 67 (25):2996-3010. DOI:10.1016/j.jacc.2016.03.590 PMID: 27339497
  3. ↑ Baris L, Cornette J, Johnson MR, Sliwa K, Roos-Hesselink JW (2019). "Peripartum cardiomyopathy: disease or syndrome?". Heart. 105 (5): 357–362. doi:10.1136/heartjnl-2018-314252. PMC 6613742 Check |pmc= value (help). PMID 31693481.
  4. ↑ Weintraub RG, Semsarian C, Macdonald P (2017). "Dilated cardiomyopathy". Lancet. 390 (10092): 400–414. doi:10.1016/S0140-6736(16)31713-5. PMID 28190577.
  5. ↑ Favalli V, Serio A, Grasso M, Arbustini E (2016). "Genetic causes of dilated cardiomyopathy". Heart. 102 (24): 2004–2014. doi:10.1136/heartjnl-2015-308190. PMID 27634407.

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