Substance or medication-induced depressive disorder: Difference between revisions
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{{Clinical depression}} | {{Clinical depression}} | ||
{{CMG}} {{AE}} {{KS}} | {{CMG}}; {{AE}} {{KS}} | ||
==Overview== | ==Overview== | ||
Substance-induced depressive disorder is characterized by a persistent depressed mood that developed during or after substance intoxication or withdrawal or after exposure to a medication. | Substance-induced depressive disorder is characterized by a persistent depressed mood that developed during or after substance intoxication or withdrawal or after exposure to a medication. | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Substance- or medication-induced depression must be differentiated from: | |||
*[[Depressive disorder]] due to another medical condition | *[[Depressive disorder]] due to another medical condition | ||
*Primary [[depressive disorder]] | *Primary [[depressive disorder]] | ||
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==Risk Factors== | ==Risk Factors== | ||
Risk factors for the development of substance- or medication-induced depressive disorder include: | |||
*[[Antisocial behavior]] | *[[Antisocial behavior]] | ||
*[[Alcohol]] or drug use disorders | *[[Alcohol]] or drug use disorders | ||
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'''''AND''''' | '''''AND''''' | ||
*B. There is evidence from the history, physical examination, or laboratory findings of both (1)and(2): | *B. There is evidence from the history, physical examination, or laboratory findings of both (1) and (2): | ||
:*1. The symptoms in Criterion A developed during or soon after substance intoxication or withdrawal or after exposure to a medication. | :*1. The symptoms in Criterion A developed during or soon after substance intoxication or withdrawal or after exposure to a medication. | ||
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'''''AND''''' | '''''AND''''' | ||
*D. | *D. The disturbance does not occur exclusively during the course of a [[delirium]]. | ||
'''''AND''''' | '''''AND''''' | ||
Latest revision as of 19:30, 23 August 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]
Overview
Substance-induced depressive disorder is characterized by a persistent depressed mood that developed during or after substance intoxication or withdrawal or after exposure to a medication.
Differential Diagnosis
Substance- or medication-induced depression must be differentiated from:
- Depressive disorder due to another medical condition
- Primary depressive disorder
- Substance intoxication and withdrawal[1]
Epidemiology and Demographics
Prevalence
The prevalence of substance or medication-induced depressive disorder is 260 per 100,000 (0.26%) of the overall population.[1]
Risk Factors
Risk factors for the development of substance- or medication-induced depressive disorder include:
- Antisocial behavior
- Alcohol or drug use disorders
- Family history of substance use disorders
- History of drug induced depression
- History of stressful life events
- History of major depressive disorder
- Psychosocial stressors
- Specific type of medication
- Effavirenz
- High estrogen/Progesterone in OCP
- Interferon alpha
- Prednisone[1]
Diagnostic Criteria
DSM-V Diagnostic Criteria for Substance/Medication-Induced Depressive Disorder [1]
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Note: This diagnosis should be made instead of a diagnosis of substance intoxication or substance withdrawal only when the symptoms in Criterion A predominate in the clinical picture and when they are sufficiently severe to warrant clinical attention. |
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