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'''Asthenia''' ([[Greek language|Greek]]: ''ασθένεια'', lit. ''lack of strength'' but also ''disease'') is a medical term denoting a feeling of [[weakness (medical)|weakness]] without actual [[muscle weakness|loss of strength]].  
'''Asthenia''' ([[Greek language|Greek]]: ''ασθένεια'', lit. ''lack of strength'' but also ''disease'') is a medical term denoting a feeling of [[weakness (medical)|weakness]] without actual [[muscle weakness|loss of strength]].  


==Causes of asthenia==
==Causes of asthenia==
The condition is commonly seen in patients suffering from chronic fatigue syndrome, sleep disorders or chronic disorders of the heart, lungs or kidneys.
===Common Causes===
Differentiating between asthenia and true [[muscle weakness|muscular weakness]] is often difficult, and in time asthenia in chronic disorders is seen to progress into a primary weakness. Also a condition in which the body lacks or has lost strength either as a whole or in any of its parts. General asthenia occurs in many chronic wasting diseases, such as anemia and cancer, and is probably most marked in diseases of the adrenal gland. Asthenia may be limited to certain [[organs]] or systems of organs, as in [[asthenopia]], characterized by ready fatiguability.
*[[Addison's disease]]
*[[Anemia]]
*[[Anxiety]]
*[[Chemotherapy]]
*[[Chronic fatigue syndrome]]
*[[Chronic pain]]
*[[Deconditioning / sedentary lifestyle]]
*[[Dehydration and electrolyte disturbance]]
*[[Depression]]
*[[Diabetes]]
*[[Drug side effects]]
*[[Fibromyalgia]]
*[[Heart disease]]
*[[Hypothyroidism]]
*[[Infections]]
*[[Narcotics]]
*[[Paraneoplastic syndrome]]
*[[Pregnancy/postpartum]]
*[[Pulmonary disease]]
*[[Renal disease]]
*[[Sleep disorders]]
 
===Causes by Organ System===
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Heart disease]]
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Chemotherapy]], [[Narcotics]], [[Acamprosate calcium]], [[Adefovir]], [[Aprepitant]], [[Atovaquone-Proguanil]], [[Bicalutamide]],  [[Busulfan]], [[Cefaclor]], [[Dalfampridine]], [[Desmopressin]], [[Docetaxel]], [[Efavirenz]], [[Enzalutamide]], [[Eribulin]], [[Eslicarbazepine acetate]], [[Fluvoxamine]],[[Fosfomycin]], [[Fulvestrant]], [[Granisetron]], [[Interferon alfa-2b ]], [[Pegylated interferon alfa-2a]], [[Irinotecan hydrochloride]], [[Meropenem]], [[Nabilone]],  [[Netupitant and palonosetron]], [[Oxaprozin]], [[Palbociclib]], [[Panitumumab]], [[Perampanel]], [[Pilocarpine]], [[Pyridostigmine]], [[Ribavirin]], [[Ritonavir]], [[Sargramostim]], [[Sunitinib]], [[Temozolomide]], [[Teniposide]]
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| [[Addison's disease]],  [[Diabetes]],  [[Hypothyroidism]],
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| [[Anemia]]
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| [[Chemotherapy]]
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| [[Infections]]
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| [[Chronic fatigue syndrome]],  [[Chronic pain]],  [[Sleep disorders]]
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| [[Diabetes]]
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| [[Pregnancy]]
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| [[Chemotherapy]], [[Paraneoplastic syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|bgcolor="Beige"| [[Narcotics]]
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| [[Anxiety]], [[Chronic fatigue syndrome]], [[Depression]]
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| [[Pulmonary disease]]
|-
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|bgcolor="Beige"| [[Dehydration and electrolyte disturbance]], [[Renal disease]],
|-
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| [[Fibromyalgia]]
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| [[Sedentary lifestyle]], [[Sleep disorders]]
|-
|}


'''Common causes of asthenia'''
===Causes in Alphabetical Order===
{{columns-list|
*[[Acamprosate calcium]]
*[[Addison's disease]]
*[[Addison's disease]]
*[[Anemia]]
*[[Anemia]]
*[[Anxiety]]
*[[Anxiety]]
*[[Aprepitant]]
*[[Benazepril hydrochloride]]
*[[Blastocarb]]
*[[Busulfan]]
*[[Carboplatin]]
*[[Chemotherapy]]
*[[Chemotherapy]]
*[[Chronic fatigue syndrome]]
*[[Chronic fatigue syndrome]]
*[[Chronic pain]]
*[[Chronic pain]]
*[[Deconditioning]] / [[sedentary lifestyle]]
*[[Cladribine]]
*[[Dehydration]] and [[electrolyte disturbance]]
*[[Deconditioning / sedentary lifestyle]]
*[[Drugs]]- [[Metformin]], [[Paroxetine]]
*[[Dehydration and electrolyte disturbance]]
*[[Clinical depression|Depression]]
*[[Depression]]
*[[Desmopressin]]
*[[Diabetes]]
*[[Diabetes]]
*[[Docetaxel]]
*[[Drug side effects]]
*[[Efavirenz]]
*[[Encainide hydrochloride]]
*[[Enkaid]]
*[[Eribulin]]
*[[Fibromyalgia]]
*[[Fibromyalgia]]
*[[Granisetron]]
*[[Heart disease]]
*[[Heart disease]]
*[[Hypothyroidism]]
*[[Hypothyroidism]]
*[[Infections]]
*[[Infections]]
*[[Medications]] including [[amiodarone]], conjugated estrogen.
*[[Irinotecan hydrochloride]]
*[[Leustatin]]
*[[Lotensin]]
*[[Nabilone]]
*[[Narcotics]]
*[[Narcotics]]
*[[Oxaprozin]]
*[[Palbociclib]]
*[[Panitumumab]]
*[[Paraneoplastic syndrome]]
*[[Paraneoplastic syndrome]]
*[[Pregnancy]]/[[postpartum]]
*[[Paraplatin]]
*[[Respiratory disease|Pulmonary disease]]
*[[Pegylated interferon alfa-2a]]
*[[Pregnancy/postpartum]]
*[[Pulmonary disease]]
*[[Pyridostigmine]]
*[[Renal disease]]
*[[Renal disease]]
*[[Ribavirin]]
*[[Sargramostim]]
*[[Sleep disorders]]
*[[Sleep disorders]]
 
*[[Sunitinib]]
*[[Temozolomide]]
*[[Teniposide]]
}}
==See also==
==See also==
*[[Neurasthenia]]
*[[Neurasthenia]]

Latest revision as of 20:16, 10 January 2020

Asthenia
ICD-10 R53
ICD-9 780.7

Template:Search infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Asthenia (Greek: ασθένεια, lit. lack of strength but also disease) is a medical term denoting a feeling of weakness without actual loss of strength.

Causes of asthenia

Common Causes

Causes by Organ System

Cardiovascular Heart disease
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Chemotherapy, Narcotics, Acamprosate calcium, Adefovir, Aprepitant, Atovaquone-Proguanil, Bicalutamide, Busulfan, Cefaclor, Dalfampridine, Desmopressin, Docetaxel, Efavirenz, Enzalutamide, Eribulin, Eslicarbazepine acetate, Fluvoxamine,Fosfomycin, Fulvestrant, Granisetron, Interferon alfa-2b , Pegylated interferon alfa-2a, Irinotecan hydrochloride, Meropenem, Nabilone, Netupitant and palonosetron, Oxaprozin, Palbociclib, Panitumumab, Perampanel, Pilocarpine, Pyridostigmine, Ribavirin, Ritonavir, Sargramostim, Sunitinib, Temozolomide, Teniposide
Ear Nose Throat No underlying causes
Endocrine Addison's disease, Diabetes, Hypothyroidism,
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic Anemia
Iatrogenic Chemotherapy
Infectious Disease Infections
Musculoskeletal/Orthopedic No underlying causes
Neurologic Chronic fatigue syndrome, Chronic pain, Sleep disorders
Nutritional/Metabolic Diabetes
Obstetric/Gynecologic Pregnancy
Oncologic Chemotherapy, Paraneoplastic syndrome
Ophthalmologic No underlying causes
Overdose/Toxicity Narcotics
Psychiatric Anxiety, Chronic fatigue syndrome, Depression
Pulmonary Pulmonary disease
Renal/Electrolyte Dehydration and electrolyte disturbance, Renal disease,
Rheumatology/Immunology/Allergy Fibromyalgia
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Sedentary lifestyle, Sleep disorders

Causes in Alphabetical Order

See also

References

  • Adapted from: Hinshaw DB, Carnahan JM, Johnson DL. Depression, anxiety, and asthenia in advanced illness. J Am Coll Surg 2002;195:276.


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