Thrombocytopenia causes: Difference between revisions

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__NOTOC__
__NOTOC__
{{Thrombocytopenia}}
{{Thrombocytopenia}}
{{CMG}}; {{AE}} {{Ochuko}}
{{CMG}}; {{AE}} {{Ochuko}}, [https://www.wikidoc.org/index.php/User:Farbod_Zahedi_Tajrishi <nowiki>Farbod Zahedi Tajrishi, M.D. [2]</nowiki>]


==Overview==
==Overview==
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===Causes by Organ System===
===Causes by Organ System===
 
{| style="width:80%; height:100px" border="1"
 
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
{|style="width:80%; height:100px" border="1"
| style="width:75%" bgcolor="Beige" ; border="1" | [[Disseminated intravascular coagulation]], [[endocarditis]], [[pulmonary embolism]]
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Disseminated intravascular coagulation]], [[endocarditis]], [[pulmonary embolism]]
|-
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning'''
|bgcolor="Beige"| [[Strontium-89]],[[zinc]]
| bgcolor="Beige" | [[Strontium-89]],[[zinc]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dental'''
| '''Dental'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| [[Cholesterol embolism]], [[Elejalde syndrome]], [[Griscelli syndrome|Griscelli syndrome type 1]], [[neuroectodermal melanolysosomal disease]], [[post-transfusion purpura]]
| bgcolor="Beige" | [[Cholesterol embolism]], [[Elejalde syndrome]], [[Griscelli syndrome|Griscelli syndrome type 1]], [[neuroectodermal melanolysosomal disease]], [[post-transfusion purpura]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| [[5-azacytidine]], [[abciximab]], [[Acetaminophen and Oxycodone]], [[aclarubicin]], [[actinomycin D]], [[aflibercept]], [[aggrastat]], [[albendazole]], [[alemtuzumab]], [[altretamine]], [[amiodarone]], [[amphotericin B]], [[amrinone]], [[amsacrine]], [[anagrelide]], [[anazolene]], [[anti-thymocyte globulin]], [[ardeparin]], [[azathioprine]], [[bendamustine]], [[benoxaprofen]], [[bevacizumab]], [[bortezomib]], [[bosutinib]], [[brentuximab vedotin]], [[cabazitaxel]], [[capecitabine]], [[captopril]], [[carboplatin]], [[carfilzomib]], [[carmustine]], [[caspofungin]], [[chlorambucil]], [[chloramphenicol]], [[cilazapril]], [[cimetidine]], [[cisplatin]], [[cladribine]], [[clofarabine]], [[cytosine arabinoside]], [[dacarbazine]], [[dasatinib]], [[daunorubicin]], [[decitabine]], [[desferrioxamine]], [[docetaxel]], [[doxorubicin]], [[doxycycline]], [[platelet|drug-induced thrombocytopenia]], [[efalizumab]], [[eflornithine]], [[enoxaparin]], [[epirubicin]], [[eptifibatide]], [[etoposide]], [[everolimus]], [[febuxostat]], [[flucytosine]], [[fludarabine]], [[fluorouracil]], [[fondaparinux]], [[foscarnet]], [[ganciclovir]], [[gemcitabine]], [[gemtuzumab ozogamicin]], [[glycoprotein IIb/IIIa inhibitors]], [[gold salts]], [[guanidinium]], [[haem arginate]], [[heparin]], [[hydroxycarbamide]], [[hydroxychloroquine]], [[ibitumomab tiuxetan]], [[ibrutinib]], [[idarubicin]], [[ifosfamide]], [[imatinib mesylate]], [[indomethacin]], [[integrilin]], [[interferon alpha]], [[Interferon beta- 1a]],  [[interleukin 10]], [[interleukin 2]], [[irinotecan]], [[isotretinoin]], [[ixabepilone]], [[lenalidomide]], [[linezolid]], [[lomustine]], [[low molecular weight heparin]]s, [[melphalan]], [[mercaptopurine]], [[methimazole]], [[methotrexate]], [[methyldopa]], [[methyldopate]], [[methylphenidate]], [[micafungin]], [[minocycline hydrochloride]] [[mithramycin]], [[mitomycin C]], [[mitoxantrone]], [[MMR vaccine]], [[montelukast]], [[nabumetone]], [[nelarabine]], [[niacin]], [[nilotinib]], [[nitisinone]], [[obinutuzumab]], [[omacetaxine mepesuccinate]], [[oxaliplatin]], [[oxcarbazepine]], [[paclitaxel]], [[panobinostat]], [[para-amino salicylic acid]], [[pazopanib]], [[pemetrexed]], [[penicillamine]], [[pentamidine Isethionate]], [[pentostatin]], [[phenylbutazone]], [[phenytoin]], [[pixantrone]], [[pomalidomide]], [[ponatinib]], [[pralatrexate]], [[pramipexole]], [[procarbazine]], [[promethazine]], [[proton pump inhibitors]],
| bgcolor="Beige" | [[Ado-trastuzumab emtansine]], [[albendazole]], [[alemtuzumab]], [[altretamine]], [[amiodarone]], [[Amoxicillin]], [[amphotericin B]], [[amrinone]], [[amsacrine]], [[anagrelide]], [[anazolene]], [[anti-thymocyte globulin]], [[ardeparin]], [[Asenapine maleate]], [[Aspirin]], [[azathioprine]], [[Azacitidine]], [[Aztreonam]], [[bendamustine]], [[benoxaprofen]], [[Beractant]], [[bevacizumab]], [[Boceprevir]], [[bortezomib]], [[bosutinib]], [[brentuximab vedotin]], [[cabazitaxel]],  [[Cabozantinib]], [[capecitabine]], [[captopril]], [[carboplatin]], [[carfilzomib]], [[carmustine]], [[caspofungin]], [[Cefadroxil]], [[Cefepime]], [[Cefotaxime sodium]], [[Ceftazidime]],  [[Cefaclor]], [[Certolizumab pegol]], [[Chlorpropamide]] , [[chlorambucil]], [[chloramphenicol]],[[clofarabine]],  [[Cidofovir]], [[cilazapril]], [[cimetidine]], [[cisplatin]], [[cladribine]], [[Clemastine]], [[clofarabine]], [[Clobazam]], [[Cyclophosphamide]], [[Cytarabine]], [[cytosine arabinoside]], [[dacarbazine]], [[Dactinomycin]], [[dasatinib]], [[daunorubicin]], [[decitabine]], [[deferasirox]], [[desferrioxamine]], [[Desmopressin]], [[Dexchlorpheniramine]], [[Dexrazoxane]], [[Dextran]] [[Didanosine]], [[diflunisal]], [[docetaxel]], [[Doxorubicin Hydrochloride]], [[doxycycline]], [[Rifampin]] [[platelet|drug-induced thrombocytopenia]], [[efalizumab]], [[eflornithine]], [[Eltrombopag]], [[enoxaparin]], [[Epirubicin hydrochloride]], [[eptifibatide]], [[Eribulin]], [[Ethambutol]], [[Ethacrynic Acid]], [[etoposide]], [[everolimus]], [[febuxostat]], [[Felbamate]], [[Filgastrim]], [[flucytosine]], [[fludarabine]], [[fluorouracil]], [[fondaparinux]], [[foscarnet]], [[ganciclovir]], [[gemcitabine]], [[gemtuzumab ozogamicin]], [[glycoprotein IIb/IIIa inhibitors]], [[gold salts]], [[guanidinium]], [[Guanidine]], [[haem arginate]], [[heparin]], [[Hydrocodone bitartrate and acetaminophen]], [[hydroxycarbamide]], [[hydroxychloroquine]], [[Hydroxyurea (patient information)]], [[ibitumomab tiuxetan]], [[ibuprofen lysine]], [[ibrutinib]], [[idarubicin]], [[ifosfamide]], [[imatinib mesylate]], [[Indinavir]], [[indomethacin]], [[integrilin]], [[interferon alpha]], [[interferon alfacon-1]], [[Imipenem-Cilastatin]],[[Interferon beta- 1a]],  [[Interferon gamma]], [[interleukin 10]], [[interleukin 2]], [[irinotecan hydrochloride]], [[Isoniazid]], [[isotretinoin]], [[ixabepilone]], [[Lapatinib]],[[lenalidomide]], [[Letrozole]], [[linezolid]], [[lomustine]], [[low molecular weight heparin]]s, [[Loxapine]], [[melphalan]], [[mercaptopurine]], [[Meropenem]], [[methimazole]], [[methotrexate]], [[methyldopa]], [[methyldopate]], [[methylphenidate]], [[micafungin sodium]], [[Milnacipran hydrochloride]], [[minocycline hydrochloride]], [[miltefosine]], [[mithramycin]], [[mitomycin]], [[mitoxantrone]], [[MMR vaccine]], [[montelukast]], [[nabumetone]], [[nelarabine]], [[niacin]], [[nilotinib]], [[nitisinone]], [[Nizatidine]], [[obinutuzumab]], [[Ofatumumab]], [[Omacetaxine]], [[omacetaxine mepesuccinate]], [[Olsalazine]], [[oxaliplatin]], [[Oxaprozin]], [[oxcarbazepine]], [[Oxytetracycline]], [[paclitaxel]], [[Palbociclib]], [[panobinostat]], [[para-amino salicylic acid]], [[pazopanib]], [[Pegademase]], [[Peginterferon Beta-1a]],[[pemetrexed]], [[penicillamine]], [[pentamidine Isethionate]], [[pentostatin]], [[phenylbutazone]], [[phenytoin]], [[Pergolide]], [[Pertuzumab]], [[pixantrone]], [[Plerixafor]], [[pomalidomide]], [[ponatinib]], [[pralatrexate]], [[pramipexole]], [[procarbazine]], [[promethazine]], [[proton pump inhibitors]], [[pyrimethamine]], [[quinidine]], [[quinine]], [[Rabeprazole]], [[Radium chloride]], [[raltitrexed]], [[ranitidine]], [[regorafenib]], [[reoPro]], [[repaglinide]], [[rifampicin]], [[Ritonavir]], [[rituximab]], [[romidepsin]], [[Romiplostim]], [[ruxolitinib]], [[Siltuximab]], [[sirolimus]], [[Sodium aurothiomalate]], [[sorafenib]], [[stiripentol]], [[Streptozocin]], [[Sulfacetamide]], [[Sulfamethoxazole/Trimethoprim (oral)]], [[sulfasalazine]], [[sulindac]], [[sulfonamides]], [[sunitinib malate]], [[Spironolactone]], [[Tacrolimus]], [[Tamoxifen]], [[temozolomide]], [[temsirolimus]], [[teniposide]], [[thalidomide]], [[thioguanine]], [[thiotepa]], [[Thiothixene]], [[Tiagabine]], [[ticlopidine]], [[tinzaparin]], [[tirofiban]],  [[tocilizumab]], [[topotecan]], [[Tolmetin]], [[Tolazamide]], [[Toremifene]], [[tositumomab iodine-131]], [[trabectedin]], [[Trimethadione]], [[trimethoprim-sulfamethoxazole]], [[tolbutamide]], [[valganciclovir]], [[valproic acid]], [[vancomycin]], [[Vinblastine]], [[Vincristine sulfate liposome]] [[vinflunine]], [[vinorelbine]], [[vorinostat]], [[ziv-aflibercept]], [[zonisamide]]
[[pyrimethamine]], [[quinidine]], [[quinine]], [[raltitrexed]], [[ranitidine]], [[regorafenib]], [[reoPro]], [[repaglinide]], [[rifampicin]], [[rituximab]], [[romidepsin]], [[ruxolitinib]], [[sirolimus]], [[sorafenib]], [[stiripentol]], [[sulfasalazine]], [[sulindac]], [[sulfonamides]], [[sunitinib malate]], [[Tacrolimus]], [[Tamoxifen]], [[temozolomide]], [[temsirolimus]], [[teniposide]], [[thioguanine]], [[thiotepa]], [[ticlopidine]], [[tinzaparin]], [[tirofiban]], [[topotecan]], [[tositumomab iodine-131]], [[trabectedin]], [[trimethoprim-sulfamethoxazole]], [[valganciclovir]], [[valproic acid]], [[vancomycin]], [[vinflunine]], [[vinorelbine]], [[vorinostat]], [[ziv-aflibercept]], [[zonisamide]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
| '''Ear Nose Throat'''
|bgcolor="Beige"| [[Alport syndrome]], [[Arias oculootoradial syndrome]], [[Epstein's syndrome]], [[Fechtner syndrome]]
| bgcolor="Beige" | [[Alport syndrome]], [[Arias oculootoradial syndrome]], [[Epstein's syndrome]], [[Fechtner syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| [[Immunodysregulation polyendocrinopathy and enteropathy, X-linked]]
| bgcolor="Beige" | [[Immunodysregulation polyendocrinopathy and enteropathy, X-linked]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Environmental'''
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| [[aminoaciduria|Dibasic aminoaciduria type 2]], [[liver failure]], [[Niemann-Pick disease|Niemann-Pick disease type b]], [[portal hypertension]], [[Shwachman-Diamond syndrome]]
| bgcolor="Beige" | [[aminoaciduria|Dibasic aminoaciduria type 2]], [[liver failure]], [[Niemann-Pick disease|Niemann-Pick disease type b]], [[portal hypertension]], [[Shwachman-Diamond syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| [[Aicardi-Goutieres syndrome]], [[Alport syndrome]], [[Chediak-Higashi disease]], [[factor H|complement factor H deficiency]], [[Elejalde syndrome]], [[Fanconi anaemia]], [[Fechtner syndrome]], [[Griscelli syndrome|Griscelli syndrome type 1]], [[holocarboxylase synthase deficiency]], [[iminodipeptiduria]], [[Jacobsen syndrome]], [[MELAS]], [[neuroectodermal melanolysosomal disease]], [[Niemann-Pick disease|Niemann-Pick disease type b]], [[Omenn syndrome]], [[Paris-Trousseau thrombocytopenia]], [[Shwachman-Diamond syndrome]], [[TAR syndrome]], [[TAR syndrome|Thrombocytopenia absent radius syndrome]], [[Von Willebrand disease|Von Willebrand disease, platelet type]], [[Wiskott-Aldrich syndrome]], [[X-linked hyperimmunoglobulin M syndrome]]
| bgcolor="Beige" | [[Aicardi-Goutieres syndrome]], [[Alport syndrome]], [[Chediak-Higashi disease]], [[factor H|complement factor H deficiency]], [[Elejalde syndrome]], [[Fanconi anaemia]], [[Fechtner syndrome]], [[Griscelli syndrome|Griscelli syndrome type 1]], [[holocarboxylase synthase deficiency]], [[iminodipeptiduria]], [[Jacobsen syndrome]], [[MELAS]], [[neuroectodermal melanolysosomal disease]], [[Niemann-Pick disease|Niemann-Pick disease type b]], [[Omenn syndrome]], [[Paris-Trousseau thrombocytopenia]], [[Shwachman-Diamond syndrome]], [[TAR syndrome]], [[TAR syndrome|Thrombocytopenia absent radius syndrome]], [[Von Willebrand disease|Von Willebrand disease, platelet type]], [[Wiskott-Aldrich syndrome]], [[X-linked hyperimmunoglobulin M syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| [[Acquired pure megakaryocytic aplasia]], [[aplastic anemia]], [[Bernard-Soulier syndrome]], [[thrombocytopenia|congenital amegakaryocytic thrombocytopenia (CAMT)]], [[disseminated intravascular coagulation]], [[Epstein's syndrome]], [[familial histiocytic reticulosis]], [[Gasser syndrome]], [[GATA1|GATA1-related cytopenia]], [[Glanzmann's thrombasthenia]], [[grey platelet syndrome]], [[hemolytic uremic syndrome]], [[histiocytosis X]], [[hypersplenism]], [[idiopathic thrombocytopenic purpura]], [[Jacobsen syndrome]], [[Kasabach-Merritt syndrome]], [[May-Hegglin anomaly]], [[Moschcowitz syndrome]], [[myelodysplastic syndrome]], [[myelofibrosis]], [[neonatal alloimmune thrombocytopenia]], [[pancytopenia]], [[Paris-Trousseau thrombocytopenia]], [[paroxysmal nocturnal hemoglobinuria]], [[post-transfusion purpura]], [[pulmonary embolism]], [[TAR syndrome|radial aplasia-thrombocytopenia syndrome]], [[Sebastian platelet syndrome]], [[Shwachman-Diamond syndrome]], [[thrombotic thrombocytopenic purpura]], [[Von Willebrand disease|Von Willebrand disease, platelet type]], [[Werlhof disease]], [[Wiskott-Aldrich syndrome]]
| bgcolor="Beige" | [[Acquired pure megakaryocytic aplasia]], [[aplastic anemia]], [[Bernard-Soulier syndrome]], [[thrombocytopenia|congenital amegakaryocytic thrombocytopenia (CAMT)]], [[disseminated intravascular coagulation]], [[Epstein's syndrome]], [[familial histiocytic reticulosis]], [[Gasser syndrome]], [[GATA1|GATA1-related cytopenia]], [[Glanzmann's thrombasthenia]], [[grey platelet syndrome]], [[hemolytic uremic syndrome]], [[histiocytosis X]], [[hypersplenism]], [[idiopathic thrombocytopenic purpura]], [[Jacobsen syndrome]], [[Kasabach-Merritt syndrome]], [[May-Hegglin anomaly]], [[Moschcowitz syndrome]], [[myelodysplastic syndrome]], [[myelofibrosis]], [[neonatal alloimmune thrombocytopenia]], [[pancytopenia]], [[Paris-Trousseau thrombocytopenia]], [[paroxysmal nocturnal hemoglobinuria]], [[post-transfusion purpura]], [[pulmonary embolism]], [[TAR syndrome|radial aplasia-thrombocytopenia syndrome]], [[Sebastian platelet syndrome]], [[Shwachman-Diamond syndrome]], [[thrombotic thrombocytopenic purpura]], [[Von Willebrand disease|Von Willebrand disease, platelet type]], [[Werlhof disease]], [[Wiskott-Aldrich syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| '''Iatrogenic'''
|bgcolor="Beige"| [[coronary artery bypass surgery|Cardiac bypass]], [[chemotherapy]], [[intra-aortic balloon pump|intra-aortic balloon pump placement]], [[blood transfusion|massive blood transfusion]], [[radiation therapy]]
| bgcolor="Beige" | [[coronary artery bypass surgery|Cardiac bypass]], [[chemotherapy]], [[intra-aortic balloon pump|intra-aortic balloon pump placement]], [[blood transfusion|massive blood transfusion]], [[radiation therapy]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| [[Congenital syphilis]], [[cytomegalovirus]], [[Dengue fever]], [[ehrlichiosis]], [[Epstein-Barr virus]], [[hantavirus]], [[hepatitis C]], [[HIV]], [[human granulocytic ehrlichiosis]], [[ehrlichiosis|human monocytotropic ehrlichiosis]], [[infections]], [[infectious mononucleosis]], [[lassa fever]], [[leptospirosis]], [[malaria]], [[measles]], [[mumps]], [[mycoplasma pneumonia]], [[relapsing fever|Oklahoma tick fever]], [[parvovirus]], [[Q fever]], [[rubella]], [[septicaemia]], [[tick-borne encephalitis]], [[toxic shock syndrome|toxic shock syndrome (staphylococcal)]], [[varicella]], [[visceral leishmaniasis]]
| bgcolor="Beige" | [[Congenital syphilis]], [[cytomegalovirus]], [[Dengue fever]], [[ehrlichiosis]], [[Epstein-Barr virus]], [[hantavirus]], [[hepatitis C]], [[HIV]], [[human granulocytic ehrlichiosis]], [[ehrlichiosis|human monocytotropic ehrlichiosis]], [[infections]], [[infectious mononucleosis]], [[lassa fever]], [[leptospirosis]], [[malaria]], [[measles]], [[mumps]], [[mycoplasma pneumonia]], [[relapsing fever|Oklahoma tick fever]], [[parvovirus]], [[Q fever]], [[rubella]], [[septicaemia]], [[tick-borne encephalitis]], [[toxic shock syndrome|toxic shock syndrome (staphylococcal)]], [[varicella]], [[visceral leishmaniasis]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| [[Arias oculootoradial syndrome]], [[cholesterol embolism]], [[TAR syndrome|radial aplasia-thrombocytopenia syndrome]], [[TAR syndrome]], [[TAR syndrome|thrombocytopenia absent radius syndrome]]
| bgcolor="Beige" | [[Arias oculootoradial syndrome]], [[cholesterol embolism]], [[TAR syndrome|radial aplasia-thrombocytopenia syndrome]], [[TAR syndrome]], [[TAR syndrome|thrombocytopenia absent radius syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| [[Aicardi-Goutieres syndrome]], [[Jacobsen syndrome]]
| bgcolor="Beige" | [[Aicardi-Goutieres syndrome]], [[Jacobsen syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| [[aminoaciduria|Dibasic aminoaciduria type 2]], [[folate deficiency]], [[Gaucher disease]], [[holocarboxylase synthase deficiency]], [[iminodipeptiduria]], [[iron deficiency]], [[isovaleric acidaemia]], [[methylmalonic aciduria|methylmalonic aciduria type 2]], [[CD36|platelet glycoprotein 4 deficiency]], [[platelet glycoprotein Ib deficiency]], [[prolidase deficiency]], [[propionyl-CoA carboxylase deficiency]], [[sea blue histiocytosis]], [[sitosterolemia]], [[vitamin B12 deficiency]]
| bgcolor="Beige" | [[aminoaciduria|Dibasic aminoaciduria type 2]], [[folate deficiency]], [[Gaucher disease]], [[holocarboxylase synthase deficiency]], [[iminodipeptiduria]], [[iron deficiency]], [[isovaleric acidaemia]], [[methylmalonic aciduria|methylmalonic aciduria type 2]], [[CD36|platelet glycoprotein 4 deficiency]], [[platelet glycoprotein Ib deficiency]], [[prolidase deficiency]], [[propionyl-CoA carboxylase deficiency]], [[sea blue histiocytosis]], [[sitosterolemia]], [[vitamin B12 deficiency]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| [[Eclampsia]], [[HELLP syndrome]], [[pre-eclampsia]]
| bgcolor="Beige" | [[Eclampsia]], [[HELLP syndrome]], [[pre-eclampsia]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[acute myeloid leukemia]], [[acute promyelocytic leukemia]], [[chronic lymphocytic leukaemia]], [[chronic myeloid leukaemia]], [[hairy cell leukaemia]], [[hepatosplenic T-cell lymphoma]], [[histiocytosis X]], [[Kasabach-Merritt syndrome]], [[lymphoma]], [[myeloma]], [[Non-Hodgkins lymphoma]], [[paraneoplastic syndrome]]
| bgcolor="Beige" | [[Acute lymphoblastic leukemia]], [[acute myeloid leukemia]], [[acute promyelocytic leukemia]], [[chronic lymphocytic leukaemia]], [[chronic myeloid leukaemia]], [[hairy cell leukaemia]], [[hepatosplenic T-cell lymphoma]], [[histiocytosis X]], [[Kasabach-Merritt syndrome]], [[lymphoma]], [[myeloma]], [[Non-Hodgkins lymphoma]], [[paraneoplastic syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| '''Ophthalmologic'''
|bgcolor="Beige"| [[Arias oculootoradial syndrome]]
| bgcolor="Beige" | [[Arias oculootoradial syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
| '''Overdose/Toxicity'''
|bgcolor="Beige"| [[Alcohol]], [[arsenic trioxide]], [[ethanol]]
| bgcolor="Beige" | [[Alcohol]], [[arsenic trioxide]], [[ethanol]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Psychiatric'''
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Pulmonary'''
| '''Pulmonary'''
|bgcolor="Beige"| [[Acute respiratory distress syndrome]], [[Niemann-Pick disease|Niemann-Pick disease type b]], [[pulmonary embolism]]
| bgcolor="Beige" | [[Acute respiratory distress syndrome]], [[Niemann-Pick disease|Niemann-Pick disease type b]], [[pulmonary embolism]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| '''Renal/Electrolyte'''
|bgcolor="Beige"| [[Alport syndrome]], [[cholesterol embolism]], [[aminoaciduria|Dibasic aminoaciduria type 2]], [[Epstein's syndrome]], [[Fechtner syndrome]], [[hemolytic uremic syndrome]]
| bgcolor="Beige" | [[Alport syndrome]], [[cholesterol embolism]], [[aminoaciduria|Dibasic aminoaciduria type 2]], [[Epstein's syndrome]], [[Fechtner syndrome]], [[hemolytic uremic syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| [[Anticardiolipin syndrome]], [[antiphospholipid syndrome]], [[autoimmune lymphoproliferative syndrome type 1]], [[autoimmune lymphoproliferative syndrome type 2]], [[factor H|complement factor H deficiency]], [[Evans syndrome]], [[immunodysregulation polyendocrinopathy and enteropathy, X-linked]], [[macrophage-activation syndrome]], [[neonatal alloimmune thrombocytopenia]], [[Omenn syndrome]], [[paraneoplastic syndrome]], [[systemic lupus erythematosus]], [[Wiskott-Aldrich syndrome]], [[X-linked hyperimmunoglobulin M syndrome]]
| bgcolor="Beige" | [[Anticardiolipin syndrome]], [[antiphospholipid syndrome]], [[autoimmune lymphoproliferative syndrome type 1]], [[autoimmune lymphoproliferative syndrome type 2]], [[factor H|complement factor H deficiency]], [[Evans syndrome]], [[immunodysregulation polyendocrinopathy and enteropathy, X-linked]], [[macrophage-activation syndrome]], [[neonatal alloimmune thrombocytopenia]], [[Omenn syndrome]], [[paraneoplastic syndrome]], [[systemic lupus erythematosus]], [[Wiskott-Aldrich syndrome]], [[X-linked hyperimmunoglobulin M syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Sexual'''
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Urologic'''
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| [[Snakebites]]
| bgcolor="Beige" | [[Snakebites]]
|-
|-
|}
|}
Line 164: Line 161:
*[[Acute promyelocytic leukemia]]
*[[Acute promyelocytic leukemia]]
*[[Acute respiratory distress syndrome]]
*[[Acute respiratory distress syndrome]]
*[[Ado-trastuzumab emtansine]]
*[[Aflibercept]]
*[[Aflibercept]]
*[[Aggrastat]]
*[[Aggrastat]]
Line 173: Line 171:
*[[Altretamine]]
*[[Altretamine]]
*[[Amiodarone]]
*[[Amiodarone]]
*[[Amoxicillin]]
*[[Amphotericin B]]
*[[Amphotericin B]]
*[[Amrinone]]
*[[Amrinone]]
Line 188: Line 187:
*[[Autoimmune lymphoproliferative syndrome type 2]]
*[[Autoimmune lymphoproliferative syndrome type 2]]
*[[Azathioprine]]
*[[Azathioprine]]
*[[Aztreonam]]
*[[Bendamustine]]  
*[[Bendamustine]]  
*[[Benoxaprofen]]
*[[Benoxaprofen]]
*[[Bernard-Soulier syndrome]]
*[[Bernard-Soulier syndrome]]
*[[Bevacizumab]]
*[[Bevacizumab]]
*[[Boceprevir]]
*[[Bortezomib]]
*[[Bortezomib]]
*[[Bosutinib]]
*[[Bosutinib]]
Line 203: Line 204:
*[[Carmustine]]
*[[Carmustine]]
*[[Caspofungin]]  
*[[Caspofungin]]  
*[[Cefadroxil]]
*[[Cefepime]]
*[[Cefotaxime sodium]]
*[[Ceftazidime]]
*[[Chediak-Higashi disease]]
*[[Chediak-Higashi disease]]
*[[Chemotherapy]]
*[[Chemotherapy]]
*[[Chlorambucil]]
*[[Chlorambucil]]
*[[Chloramphenicol]]
*[[Chloramphenicol]]
*[[Chlorpropamide]]
*[[Cholesterol embolism]]
*[[Cholesterol embolism]]
*[[Chronic lymphocytic leukaemia]]
*[[Chronic lymphocytic leukaemia]]
*[[Chronic myeloid leukaemia]]
*[[Chronic myeloid leukaemia]]
*[[Cidofovir]]
*[[Cilazapril]]
*[[Cilazapril]]
*[[Cimetidine]]  
*[[Cimetidine]]  
Line 217: Line 224:
*[[factor H|Complement factor H deficiency]]  
*[[factor H|Complement factor H deficiency]]  
*[[thrombocytopenia|Congenital amegakaryocytic thrombocytopenia (CAMT)]]   
*[[thrombocytopenia|Congenital amegakaryocytic thrombocytopenia (CAMT)]]   
*[[Cyclophosphamide]]
*[[Cytomegalovirus]]  
*[[Cytomegalovirus]]  
*[[Cytarabine]]
*[[Cytosine arabinoside]]  
*[[Cytosine arabinoside]]  
*[[Dacarbazine]]
*[[Dacarbazine]]
Line 225: Line 234:
*[[Dengue fever]]
*[[Dengue fever]]
*[[Desferrioxamine]]
*[[Desferrioxamine]]
*[[Desmopressin]]
*[[aminoaciduria|Dibasic aminoaciduria type 2]]
*[[aminoaciduria|Dibasic aminoaciduria type 2]]
*[[Didanosine]]
*[[Disseminated intravascular coagulation]]
*[[Disseminated intravascular coagulation]]
*[[Docetaxel]]
*[[Docetaxel]]
*[[Doxorubicin]]
*[[Doxorubicin Hydrochloride]]
*[[platelet|Drug-induced thrombocytopenia]]
*[[platelet|Drug-induced thrombocytopenia]]
{{col-break|width=33%}}  
{{col-break|width=33%}}  
Line 238: Line 249:
*[[Endocarditis]]  
*[[Endocarditis]]  
*[[Enoxaparin]]
*[[Enoxaparin]]
*[[Epirubicin]]  
*[[Epirubicin hydrochloride]]  
*[[Epstein's syndrome]]
*[[Epstein's syndrome]]
*[[Epstein-Barr virus]]  
*[[Epstein-Barr virus]]  
*[[Eptifibatide]]
*[[Eptifibatide]]
*[[Eribulin]]
*[[Ethanol]]  
*[[Ethanol]]  
*[[Etoposide]]
*[[Etoposide]]
Line 249: Line 261:
*[[Fanconi anaemia]]
*[[Fanconi anaemia]]
*[[Fechtner syndrome]]
*[[Fechtner syndrome]]
*[[Filgastrim]]
*[[Flucytosine]]
*[[Flucytosine]]
*[[Fludarabine]]
*[[Fludarabine]]
Line 281: Line 294:
*[[ehrlichiosis|Human monocytotropic ehrlichiosis]]
*[[ehrlichiosis|Human monocytotropic ehrlichiosis]]
*[[Hydroxycarbamide]]
*[[Hydroxycarbamide]]
*[[Hydroxyurea (patient information)]]
*[[Hypersplenism]]
*[[Hypersplenism]]
*[[Ibritumomab tiuxetan]]
*[[Ibritumomab tiuxetan]]
*[[Ibrutinib]]
*[[Ibrutinib]]
*[[Ibuprofen lysine]]
*[[Idarubicin]]
*[[Idarubicin]]
*[[Idiopathic thrombocytopenic purpura]]
*[[Idiopathic thrombocytopenic purpura]]
Line 290: Line 305:
*[[Iminodipeptiduria]]
*[[Iminodipeptiduria]]
*[[Immunodysregulation polyendocrinopathy and enteropathy, X-linked]]
*[[Immunodysregulation polyendocrinopathy and enteropathy, X-linked]]
*[[Indinavir]]
*[[Indomethacin]]
*[[Indomethacin]]
*[[Infections]]
*[[Infections]]
Line 296: Line 312:
*[[Integrilin]]
*[[Integrilin]]
*[[Interferon alpha]]  
*[[Interferon alpha]]  
*[[Interferon gamma]]
*[[Interleukin 10]]
*[[Interleukin 10]]
*[[Interleukin 2]]
*[[Interleukin 2]]
*[[intra-aortic balloon pump|Intra-aortic balloon pump placement]]
*[[intra-aortic balloon pump|Intra-aortic balloon pump placement]]
*[[Irinotecan]]
*[[Irinotecan hydrochloride]]
*[[Iron deficiency]]
*[[Iron deficiency]]
*[[Isoniazid]]
*[[Isotretinoin]]
*[[Isotretinoin]]
*[[Isovaleric acidaemia]]
*[[Isovaleric acidaemia]]
Line 328: Line 346:
*[[methylmalonic aciduria|Methylmalonic aciduria type 2]]
*[[methylmalonic aciduria|Methylmalonic aciduria type 2]]
*[[Methylphenidate]]
*[[Methylphenidate]]
*[[Micafungin]]
*[[Micafungin sodium]]
*[[Milnacipran hydrochloride]]
*[[Mithramycin]]  
*[[Mithramycin]]  
*[[Mitomycin C]]
*[[Mitomycin C]]
Line 353: Line 372:
*[[Omenn syndrome]]
*[[Omenn syndrome]]
*[[Oxaliplatin]]
*[[Oxaliplatin]]
*[[Oxaprozin]]
*[[Paclitaxel]]  
*[[Paclitaxel]]  
*[[Palbociclib]]
*[[Pancytopenia]]
*[[Pancytopenia]]
*[[Panobinostat]]
*[[Panobinostat]]
Line 362: Line 383:
*[[Parvovirus]]
*[[Parvovirus]]
*[[Pazopanib]]
*[[Pazopanib]]
*[[Peginterferon Beta-1a]]
*[[Pemetrexed]]
*[[Pemetrexed]]
*[[Penicillamine]]  
*[[Penicillamine]]  
*[[Pentamidine]]
*[[Pentamidine]]
*[[Pentostatin]]
*[[Pentostatin]]
*[[Pergolide]]
*[[Phenylbutazone]]
*[[Phenylbutazone]]
*[[Phenytoin]]
*[[Phenytoin]]
Line 371: Line 394:
*[[CD36|Platelet glycoprotein 4 deficiency]]
*[[CD36|Platelet glycoprotein 4 deficiency]]
*[[Platelet glycoprotein Ib deficiency]]
*[[Platelet glycoprotein Ib deficiency]]
*[[Plerixafor]]
*[[Pomalidomide]]  
*[[Pomalidomide]]  
*[[Ponatinib]]
*[[Ponatinib]]
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{{col-break|width=33%}}  
{{col-break|width=33%}}  
*[[Radiation therapy]]
*[[Radiation therapy]]
*[[Radium chloride]]
*[[Raltitrexed]]
*[[Raltitrexed]]
*[[Ranitidine]]
*[[Ranitidine]]
Line 402: Line 427:
*[[Septicaemia]]  
*[[Septicaemia]]  
*[[Shwachman-Diamond syndrome]]
*[[Shwachman-Diamond syndrome]]
*[[Siltuximab]]
*[[Sirolimus]]
*[[Sirolimus]]
*[[Sitosterolemia]]  
*[[Sitosterolemia]]  
Line 407: Line 433:
*[[Sorafenib]]
*[[Sorafenib]]
*[[Stiripentol]]
*[[Stiripentol]]
*[[Streptozocin]]
*[[Strontium-89]]
*[[Strontium-89]]
*[[Sulfasalazine]]
*[[Sulfasalazine]]
Line 423: Line 450:
*[[thrombocytopenia absent radius|Thrombocytopenia absent radius syndrome]]
*[[thrombocytopenia absent radius|Thrombocytopenia absent radius syndrome]]
*[[Thrombotic thrombocytopenic purpura]]  
*[[Thrombotic thrombocytopenic purpura]]  
*[[Tiagabine]]
*[[Tick-borne encephalitis]]
*[[Tick-borne encephalitis]]
*[[Ticlopidine]]
*[[Ticlopidine]]
Line 454: Line 482:
[[Category:Crowdiagnosis]]
[[Category:Crowdiagnosis]]
[[Category:Hematology]]
[[Category:Hematology]]
[[Category:Blood disorders]]


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Latest revision as of 21:43, 3 October 2018

Thrombocytopenia Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogheneochuko Ajari, MB.BS, MS [2], Farbod Zahedi Tajrishi, M.D. [2]

Overview

There are two broad mechanisms for the causes of thrombocytopenia: Reduced platelet production and increased platelet destruction. Thrombocytopenia is seen in a variety of infectious and genetic disorders as well as a side effect of a large list of medications.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Causes by Organ System

Cardiovascular Disseminated intravascular coagulation, endocarditis, pulmonary embolism
Chemical/Poisoning Strontium-89,zinc
Dental No underlying causes
Dermatologic Cholesterol embolism, Elejalde syndrome, Griscelli syndrome type 1, neuroectodermal melanolysosomal disease, post-transfusion purpura
Drug Side Effect Ado-trastuzumab emtansine, albendazole, alemtuzumab, altretamine, amiodarone, Amoxicillin, amphotericin B, amrinone, amsacrine, anagrelide, anazolene, anti-thymocyte globulin, ardeparin, Asenapine maleate, Aspirin, azathioprine, Azacitidine, Aztreonam, bendamustine, benoxaprofen, Beractant, bevacizumab, Boceprevir, bortezomib, bosutinib, brentuximab vedotin, cabazitaxel, Cabozantinib, capecitabine, captopril, carboplatin, carfilzomib, carmustine, caspofungin, Cefadroxil, Cefepime, Cefotaxime sodium, Ceftazidime, Cefaclor, Certolizumab pegol, Chlorpropamide , chlorambucil, chloramphenicol,clofarabine, Cidofovir, cilazapril, cimetidine, cisplatin, cladribine, Clemastine, clofarabine, Clobazam, Cyclophosphamide, Cytarabine, cytosine arabinoside, dacarbazine, Dactinomycin, dasatinib, daunorubicin, decitabine, deferasirox, desferrioxamine, Desmopressin, Dexchlorpheniramine, Dexrazoxane, Dextran Didanosine, diflunisal, docetaxel, Doxorubicin Hydrochloride, doxycycline, Rifampin drug-induced thrombocytopenia, efalizumab, eflornithine, Eltrombopag, enoxaparin, Epirubicin hydrochloride, eptifibatide, Eribulin, Ethambutol, Ethacrynic Acid, etoposide, everolimus, febuxostat, Felbamate, Filgastrim, flucytosine, fludarabine, fluorouracil, fondaparinux, foscarnet, ganciclovir, gemcitabine, gemtuzumab ozogamicin, glycoprotein IIb/IIIa inhibitors, gold salts, guanidinium, Guanidine, haem arginate, heparin, Hydrocodone bitartrate and acetaminophen, hydroxycarbamide, hydroxychloroquine, Hydroxyurea (patient information), ibitumomab tiuxetan, ibuprofen lysine, ibrutinib, idarubicin, ifosfamide, imatinib mesylate, Indinavir, indomethacin, integrilin, interferon alpha, interferon alfacon-1, Imipenem-Cilastatin,Interferon beta- 1a, Interferon gamma, interleukin 10, interleukin 2, irinotecan hydrochloride, Isoniazid, isotretinoin, ixabepilone, Lapatinib,lenalidomide, Letrozole, linezolid, lomustine, low molecular weight heparins, Loxapine, melphalan, mercaptopurine, Meropenem, methimazole, methotrexate, methyldopa, methyldopate, methylphenidate, micafungin sodium, Milnacipran hydrochloride, minocycline hydrochloride, miltefosine, mithramycin, mitomycin, mitoxantrone, MMR vaccine, montelukast, nabumetone, nelarabine, niacin, nilotinib, nitisinone, Nizatidine, obinutuzumab, Ofatumumab, Omacetaxine, omacetaxine mepesuccinate, Olsalazine, oxaliplatin, Oxaprozin, oxcarbazepine, Oxytetracycline, paclitaxel, Palbociclib, panobinostat, para-amino salicylic acid, pazopanib, Pegademase, Peginterferon Beta-1a,pemetrexed, penicillamine, pentamidine Isethionate, pentostatin, phenylbutazone, phenytoin, Pergolide, Pertuzumab, pixantrone, Plerixafor, pomalidomide, ponatinib, pralatrexate, pramipexole, procarbazine, promethazine, proton pump inhibitors, pyrimethamine, quinidine, quinine, Rabeprazole, Radium chloride, raltitrexed, ranitidine, regorafenib, reoPro, repaglinide, rifampicin, Ritonavir, rituximab, romidepsin, Romiplostim, ruxolitinib, Siltuximab, sirolimus, Sodium aurothiomalate, sorafenib, stiripentol, Streptozocin, Sulfacetamide, Sulfamethoxazole/Trimethoprim (oral), sulfasalazine, sulindac, sulfonamides, sunitinib malate, Spironolactone, Tacrolimus, Tamoxifen, temozolomide, temsirolimus, teniposide, thalidomide, thioguanine, thiotepa, Thiothixene, Tiagabine, ticlopidine, tinzaparin, tirofiban, tocilizumab, topotecan, Tolmetin, Tolazamide, Toremifene, tositumomab iodine-131, trabectedin, Trimethadione, trimethoprim-sulfamethoxazole, tolbutamide, valganciclovir, valproic acid, vancomycin, Vinblastine, Vincristine sulfate liposome vinflunine, vinorelbine, vorinostat, ziv-aflibercept, zonisamide
Ear Nose Throat Alport syndrome, Arias oculootoradial syndrome, Epstein's syndrome, Fechtner syndrome
Endocrine Immunodysregulation polyendocrinopathy and enteropathy, X-linked
Environmental No underlying causes
Gastroenterologic Dibasic aminoaciduria type 2, liver failure, Niemann-Pick disease type b, portal hypertension, Shwachman-Diamond syndrome
Genetic Aicardi-Goutieres syndrome, Alport syndrome, Chediak-Higashi disease, complement factor H deficiency, Elejalde syndrome, Fanconi anaemia, Fechtner syndrome, Griscelli syndrome type 1, holocarboxylase synthase deficiency, iminodipeptiduria, Jacobsen syndrome, MELAS, neuroectodermal melanolysosomal disease, Niemann-Pick disease type b, Omenn syndrome, Paris-Trousseau thrombocytopenia, Shwachman-Diamond syndrome, TAR syndrome, Thrombocytopenia absent radius syndrome, Von Willebrand disease, platelet type, Wiskott-Aldrich syndrome, X-linked hyperimmunoglobulin M syndrome
Hematologic Acquired pure megakaryocytic aplasia, aplastic anemia, Bernard-Soulier syndrome, congenital amegakaryocytic thrombocytopenia (CAMT), disseminated intravascular coagulation, Epstein's syndrome, familial histiocytic reticulosis, Gasser syndrome, GATA1-related cytopenia, Glanzmann's thrombasthenia, grey platelet syndrome, hemolytic uremic syndrome, histiocytosis X, hypersplenism, idiopathic thrombocytopenic purpura, Jacobsen syndrome, Kasabach-Merritt syndrome, May-Hegglin anomaly, Moschcowitz syndrome, myelodysplastic syndrome, myelofibrosis, neonatal alloimmune thrombocytopenia, pancytopenia, Paris-Trousseau thrombocytopenia, paroxysmal nocturnal hemoglobinuria, post-transfusion purpura, pulmonary embolism, radial aplasia-thrombocytopenia syndrome, Sebastian platelet syndrome, Shwachman-Diamond syndrome, thrombotic thrombocytopenic purpura, Von Willebrand disease, platelet type, Werlhof disease, Wiskott-Aldrich syndrome
Iatrogenic Cardiac bypass, chemotherapy, intra-aortic balloon pump placement, massive blood transfusion, radiation therapy
Infectious Disease Congenital syphilis, cytomegalovirus, Dengue fever, ehrlichiosis, Epstein-Barr virus, hantavirus, hepatitis C, HIV, human granulocytic ehrlichiosis, human monocytotropic ehrlichiosis, infections, infectious mononucleosis, lassa fever, leptospirosis, malaria, measles, mumps, mycoplasma pneumonia, Oklahoma tick fever, parvovirus, Q fever, rubella, septicaemia, tick-borne encephalitis, toxic shock syndrome (staphylococcal), varicella, visceral leishmaniasis
Musculoskeletal/Orthopedic Arias oculootoradial syndrome, cholesterol embolism, radial aplasia-thrombocytopenia syndrome, TAR syndrome, thrombocytopenia absent radius syndrome
Neurologic Aicardi-Goutieres syndrome, Jacobsen syndrome
Nutritional/Metabolic Dibasic aminoaciduria type 2, folate deficiency, Gaucher disease, holocarboxylase synthase deficiency, iminodipeptiduria, iron deficiency, isovaleric acidaemia, methylmalonic aciduria type 2, platelet glycoprotein 4 deficiency, platelet glycoprotein Ib deficiency, prolidase deficiency, propionyl-CoA carboxylase deficiency, sea blue histiocytosis, sitosterolemia, vitamin B12 deficiency
Obstetric/Gynecologic Eclampsia, HELLP syndrome, pre-eclampsia
Oncologic Acute lymphoblastic leukemia, acute myeloid leukemia, acute promyelocytic leukemia, chronic lymphocytic leukaemia, chronic myeloid leukaemia, hairy cell leukaemia, hepatosplenic T-cell lymphoma, histiocytosis X, Kasabach-Merritt syndrome, lymphoma, myeloma, Non-Hodgkins lymphoma, paraneoplastic syndrome
Ophthalmologic Arias oculootoradial syndrome
Overdose/Toxicity Alcohol, arsenic trioxide, ethanol
Psychiatric No underlying causes
Pulmonary Acute respiratory distress syndrome, Niemann-Pick disease type b, pulmonary embolism
Renal/Electrolyte Alport syndrome, cholesterol embolism, Dibasic aminoaciduria type 2, Epstein's syndrome, Fechtner syndrome, hemolytic uremic syndrome
Rheumatology/Immunology/Allergy Anticardiolipin syndrome, antiphospholipid syndrome, autoimmune lymphoproliferative syndrome type 1, autoimmune lymphoproliferative syndrome type 2, complement factor H deficiency, Evans syndrome, immunodysregulation polyendocrinopathy and enteropathy, X-linked, macrophage-activation syndrome, neonatal alloimmune thrombocytopenia, Omenn syndrome, paraneoplastic syndrome, systemic lupus erythematosus, Wiskott-Aldrich syndrome, X-linked hyperimmunoglobulin M syndrome
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Snakebites

Causes in Alphabetical Order

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Stasi R (2012). "How to approach thrombocytopenia". Hematology Am Soc Hematol Educ Program. 2012: 191–7. doi:10.1182/asheducation-2012.1.191. PMID 23233580.
  2. ↑ 2.0 2.1 2.2 2.3 Greenberg EM, Kaled ES (2013). "Thrombocytopenia". Crit Care Nurs Clin North Am. 25 (4): 427–34, v. doi:10.1016/j.ccell.2013.08.003. PMID 24267279.
  3. ↑ Farid J, Gul N, Qureshi WU, Idris M (2012). "Clinical presentations in immune thrombocytopenic purpura". J Ayub Med Coll Abbottabad. 24 (2): 39–40. PMID 24397048.
  4. ↑ Nisha S, Amita D, Uma S, Tripathi AK, Pushplata S (2012). "Prevalence and characterization of thrombocytopenia in pregnancy in Indian women". Indian J Hematol Blood Transfus. 28 (2): 77–81. doi:10.1007/s12288-011-0107-x. PMC 3332269. PMID 23730013.
  5. ↑ Abdel Karim N, Haider S, Siegrist C, Ahmad N, Zarzour A, Ying J; et al. (2013). "Approach to management of thrombotic thrombocytopenic purpura at university of cincinnati". Adv Hematol. 2013: 195746. doi:10.1155/2013/195746. PMC 3876823. PMID 24396345.

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