Itch causes: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
 
(46 intermediate revisions by 9 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Itch}}
{{Itch}}
{{CMG}}
{{CMG}} [[Ogechukwu Hannah Nnabude, MD]]
 
==Overview==
Common causes of itch include skin diseases, systemic diseases, allergies, medications, insect stings among many others


==Causes==
==Causes==
The feeling of itchiness can be caused by a movement of hair or the release of a chemical ([[histamine]]) from cells under the skin. Itchiness is regarded as protective, as it helps creatures remove [[parasites]] that land on their skin.
The feeling of itchiness can be caused by a movement of hair or the release of a chemical ([[histamine]]) from cells under the skin. Itchiness is regarded as protective, as it helps creatures remove [[parasites]] that land on their skin.


Itching can be caused by:
Causes of itching listed in alphabetical order:
*[[Xerosis]]. This is the most common cause, frequently seen in winters.  Associated with older age, frequent bathing in hot showers or baths, and high temperature and low humidity environments.
 
* [[Dermatology|Skin conditions]] (such as [[psoriasis]], [[eczema]], [[sunburn]], [[athlete's foot]] and many others). Most are of an inflammatory nature.
* Allergic reactions due to contact with specific chemicals, such as [[Urushiol]] from Poison Ivy or Poison Oak.
* Insect bites, such as those from mosquitos or chiggers.
* [[Cholestasis]] <ref name="pmid22613002">{{cite journal| author=Decock S, Roelandts R, Steenbergen WV, Laleman W, Cassiman D, Verslype C | display-authors=etal| title=Cholestasis-induced pruritus treated with ultraviolet B phototherapy: an observational case series study. | journal=J Hepatol | year= 2012 | volume= 57 | issue= 3 | pages= 637-41 | pmid=22613002 | doi=10.1016/j.jhep.2012.04.023 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22613002  }} </ref>
* Allergic reactions to contact with specific chemicals, such as [[Urushiol]] from Poison Ivy or Poison Oak.
* [[Dermatology|Skin conditions]] (such as [[psoriasis]], [[eczema]], [[sunburn]], [[athlete's foot]], [[Dandruff]] and many others). Most are of an inflammatory nature.
* [[Hodgkin's disease]]
* [[Diabetes Mellitus]]<ref name="pmid3731993">{{cite journal| author=Neilly JB, Martin A, Simpson N, MacCuish AC| title=Pruritus in diabetes mellitus: investigation of prevalence and correlation with diabetes control. | journal=Diabetes Care | year= 1986 | volume= 9 | issue= 3 | pages= 273-5 | pmid=3731993 | doi=10.2337/diacare.9.3.273 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3731993  }} </ref> <ref name="pmid18092842">{{cite journal| author=Polat M, Oztas P, Ilhan MN, Yalçin B, Alli N| title=Generalized pruritus: a prospective study concerning etiology. | journal=Am J Clin Dermatol | year= 2008 | volume= 9 | issue= 1 | pages= 39-44 | pmid=18092842 | doi=10.2165/00128071-200809010-00004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18092842  }} </ref>
* [[Jaundice]] ([[bilirubin]] is a skin irritant at high concentrations)
* Drug Side Effect: [[acamprosate calcium]], [[acetaminophen]], [[acetylcysteine]], [[acitretin]], [[aldesleukin]], [[alitretinoin]], [[aprepitant]], [[azficel-T]], betamethasone valerate]], [[bicalutamide]], [[butorphanol]], [[capsaicin]], [[caspofungin acetate]], [[cetrorelix]], [[Ceftazidime]], [[clocortolone pivalate]], [[conjugated estrogens]], [[D-Aminolevulinic acid]], [[denileukin diftitox]], [[docetaxel]], [[doxorubicin Hydrochloride]], [[diphenoxylate hydrochloride and atropine sulfate]], [[ecallantide]], [[epinastine hydrochloride]], [[epirubicin ]], [[ergotamine tartrate]], [[ethambutol]], [[felbamate]], [[fosphenytoin sodium]], [[gallium Citrate Ga 67]], [[halcinonide]], [[Histrelin]], [[hydrochlorothiazide]], [[hydrocodone bitartrate]], [[hydrocortisone butyrate]], [[Hydroxyprogesterone caproate]], [[Idursulfase]], [[imiglucerase]], [[ipilimumab]], [[ivermectin]], [[ketorolac tromethamine]], [[lidocaine (cream)]], [[meropenem]], [[mometasone furoate]], [[morphine]],[[naproxen sodium]], [[nivolumab]], [[ofloxacin]], [[omega-3-acid ethyl esters]], [[panitumumab]], [[Penciclovir]], [[piroxicam]], [[permethrin]], [[ribavirin]], [[rifampin]], [[sargramostim]], [[sertaconazole]], [[siltuximab]], [[sinecatechins]], [[sodium aurothiomalate]], [[spironolactone]], [[sulconazole]], [[tacrolimus]],[[taliglucerase alfa]] [[tazarotene]], [[thallous Chloride Tl 201]], [[tolbutamide]], [[travoprost]], [[tretinoin]], [[triazolam]], [[Trimethoprim]], [[Von Willebrand factor]]
* [[Polycythemia]], which can cause generalized itching due to increased histamine
* [[Hodgkin's disease]] <ref name="pmid20231735">{{cite journal| author=Gonçalves F| title=Thalidomide for the control of severe paraneoplastic pruritus associated with Hodgkin's disease. | journal=Am J Hosp Palliat Care | year= 2010 | volume= 27 | issue= 7 | pages= 486-7 | pmid=20231735 | doi=10.1177/1049909110362523 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20231735  }} </ref> <ref name="pmid6630598">{{cite journal| author=Kantor GR, Lookingbill DP| title=Generalized pruritus and systemic disease. | journal=J Am Acad Dermatol | year= 1983 | volume= 9 | issue= 3 | pages= 375-82 | pmid=6630598 | doi=10.1016/s0190-9622(83)70144-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6630598  }} </ref>
* [[Scabies]] or infection with [[lice]] or worms
* [[Iron deficiency]] [[anemia]] <ref name="pmid7280639">{{cite journal| author=Stäubli M| title=[Pruritus--a little known iron-deficiency symptom]. | journal=Schweiz Med Wochenschr | year= 1981 | volume= 111 | issue= 38 | pages= 1394-8 | pmid=7280639 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7280639  }} </ref>
* [[Thyroid]] illness
* Insect bites, such as those from mosquitos, ants, and ticks.
* [[Diabetes Mellitus]]
* [[Jaundice]] as ([[bilirubin]] is a skin irritant at high concentrations)
* [[Dandruff]] (an unusually large amount of flaking is associated with this sensation)
* Drug Side Effect- [[acetaminophen]], [[Bicalutamide]], [[caspofungin acetate]], [[Docetaxel]], [[Doxorubicin Hydrochloride]], [[Diphenoxylate hydrochloride and atropine sulfate]],  
[[Ergotamine tartrate]], [[Ethambutol]], [[Hydrocodone bitartrate and acetaminophen]], [[Ketorolac tromethamine]], [[Meropenem]], [[Mometasone furoate]],[[Naproxen sodium]], [[Piroxicam]], [[permethrin]], [[Ribavirin]], [[Tacrolimus]], [[Trimethoprim]], [[Von Willebrand factor]]
* [[Iron deficiency]] [[anemia]]
* Parasitic infections
* Parasitic infections
* [[Photodermatitis]] – sunlight reacts with chemicals in the skin, leading to the formation of irritant metabolites
* [[Polycythemia]], which can cause generalized itching due to increased histamine as a result of higher numbers of mast cells
* [[Psychiatric]]
* [[Psychiatric]]
* Medication:
** [[Allergy]] - (due to reaction of an individual's immune system to certain chemical compounds)
**[[Aprepitant]]
**[[Butorphanol]]
**[[Ceftazidime]]
** [[Photodermatitis]] – (sun)light reacts with chemicals in the skin, leading to the formation of irritant metabolites
** Directly (e.g. [[morphine]])
** Other drugs- [[Ofloxacin]], [[Tretinoin]] ,[[capsaicin]], [[Rifampin]]
**[[Lovaza]]
**[[Sorafenib]]
**[[Triazolam]]
**[[Tazarotene]]
**[[Travoprost]]
*[[Cholestasis]]
* Related to pregnancy:
* Related to pregnancy:
** [[Gestational pemphigoid]]
** [[Pruritic Urticarial Papules and Plaques of Pregnancy]] (PUPPP)
** [[Pruritic Urticarial Papules and Plaques of Pregnancy]] (PUPPP)
** [[Gestational pemphigoid]]
* [[Scabies]] or infection with [[lice]] or worms
*Drug side effects: [[Acamprosate calcium]], [[Acetaminophen]], [[Acetylcysteine]], [[Conjugated estrogens]], [[Betamethasone valerate]], [[Betamethasone dipropionate]], [[Ipilimumab]],[[Spironolactone]], [[Hydrochlorothiazide]], [[Ivermectin]], [[Tolbutamide]]
* [[Thyroid]] disease <ref name="pmid3766364">{{cite journal| author=Mullin GE, Eastern JS| title=Cutaneous signs of thyroid disease. | journal=Am Fam Physician | year= 1986 | volume= 34 | issue= 4 | pages= 93-8 | pmid=3766364 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3766364  }} </ref>
* [[Uremia]] <ref name="pmid18446709">{{cite journal| author=Narita I, Iguchi S, Omori K, Gejyo F| title=Uremic pruritus in chronic hemodialysis patients. | journal=J Nephrol | year= 2008 | volume= 21 | issue= 2 | pages= 161-5 | pmid=18446709 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18446709  }} </ref>
*[[Xerosis]] which is dryness of the skin, is the most common cause of itching and is frequently seen in winters. Associated with older age, frequent bathing in hot showers or baths, and high temperature and low humidity environments.


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
{{WS}}


[[Category:Needs overview]]
[[Category:Needs overview]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Signs and symptoms]]
[[Category:Primary care]]
{{WH}}
{{WS}}

Latest revision as of 13:08, 25 June 2021

Itch Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Itch from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Itch causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Itch causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Itch causes

CDC on Itch causes

Itch causes in the news

Blogs on Itch causes

Directions to Hospitals Treating Itch

Risk calculators and risk factors for Itch causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ogechukwu Hannah Nnabude, MD

Overview

Common causes of itch include skin diseases, systemic diseases, allergies, medications, insect stings among many others

Causes

The feeling of itchiness can be caused by a movement of hair or the release of a chemical (histamine) from cells under the skin. Itchiness is regarded as protective, as it helps creatures remove parasites that land on their skin.

Causes of itching listed in alphabetical order:

References

  1. ↑ Decock S, Roelandts R, Steenbergen WV, Laleman W, Cassiman D, Verslype C; et al. (2012). "Cholestasis-induced pruritus treated with ultraviolet B phototherapy: an observational case series study". J Hepatol. 57 (3): 637–41. doi:10.1016/j.jhep.2012.04.023. PMID 22613002.
  2. ↑ Neilly JB, Martin A, Simpson N, MacCuish AC (1986). "Pruritus in diabetes mellitus: investigation of prevalence and correlation with diabetes control". Diabetes Care. 9 (3): 273–5. doi:10.2337/diacare.9.3.273. PMID 3731993.
  3. ↑ Polat M, Oztas P, Ilhan MN, Yalçin B, Alli N (2008). "Generalized pruritus: a prospective study concerning etiology". Am J Clin Dermatol. 9 (1): 39–44. doi:10.2165/00128071-200809010-00004. PMID 18092842.
  4. ↑ Gonçalves F (2010). "Thalidomide for the control of severe paraneoplastic pruritus associated with Hodgkin's disease". Am J Hosp Palliat Care. 27 (7): 486–7. doi:10.1177/1049909110362523. PMID 20231735.
  5. ↑ Kantor GR, Lookingbill DP (1983). "Generalized pruritus and systemic disease". J Am Acad Dermatol. 9 (3): 375–82. doi:10.1016/s0190-9622(83)70144-1. PMID 6630598.
  6. ↑ Stäubli M (1981). "[Pruritus--a little known iron-deficiency symptom]". Schweiz Med Wochenschr. 111 (38): 1394–8. PMID 7280639.
  7. ↑ Mullin GE, Eastern JS (1986). "Cutaneous signs of thyroid disease". Am Fam Physician. 34 (4): 93–8. PMID 3766364.
  8. ↑ Narita I, Iguchi S, Omori K, Gejyo F (2008). "Uremic pruritus in chronic hemodialysis patients". J Nephrol. 21 (2): 161–5. PMID 18446709.

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Itch_causes&oldid=1705045"