Isopropyl alcohol: Difference between revisions

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{{DrugProjectFormSinglePage
{{DrugProjectFormSinglePage
|authorTag={{Ammu}}
|authorTag={{Ammu}}
|genericName=topical antimicrobial
|OTC=Yes
|aOrAn=a
|genericName=Topical antimicrobial
|drugClass=antiseptic
|aOrAn=an
|drugClass=[[antiseptic]]
|indicationType=treatment
|indicationType=treatment
|indication=cuts, scrapes and minor muscular aches
|indication=cuts, scrapes and minor [[muscular aches]]
|adverseReactions=hypersensitivity
|adverseReactions=[[hypersensitivity]]
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
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|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|drugInteractions=* Drug
|drugInteractions=<!--Use in Specific Populations-->
:* Description
 
<!--Use in Specific Populations-->
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
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<!--Administration and Monitoring-->
<!--Administration and Monitoring-->
|administration=* Topical
|administration=* [[Topical]]
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.


<!--Overdosage-->
<!--Overdosage-->
|drugBox=*
|drugBox={{chembox2
|mechAction=*
| Watchedfields = changed
 
| verifiedrevid = 477002700
<!--Structure-->
|  Name = Isopropyl alcohol
|structure=*
|  ImageFileL1 = Isopropyl alcohol.png
 
|  ImageNameL1 = Skeletal formula of isopropyl alcohol
: [[File:{{PAGENAME}}01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
|  ImageFileR1 = Isopropyl alcohol.png
 
|  ImageNameR1 = Ball-and-stick model of isopropyl alcohol
<!--Pharmacodynamics-->
|  PIN = 2-Propanol
|  IUPACName =isopropyl alcohol
|  OtherNames = Propan-2-ol; Isopropanol; [[Rubbing alcohol]]; ''sec''-Propyl alcohol; ''s''-Propanol; iPrOH; IPA
| Section1 = {{Chembox Identifiers
|  ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 17824
| SMILES = CC(O)C
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = ND2M416302
| UNNumber = 1219
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 582
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = KFZMGEQAYNKOFK-UHFFFAOYSA-N
| CASNo = 67-63-0
| CASNo_Ref = {{cascite|correct|CAS}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 3644
| PubChem = 3776
| RTECS = NT8050000
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00137
| ATCCode_prefix = D08
| ATCCode_suffix = AX05
  }}
| Section2 = {{Chembox Properties
|  C=3|H=8|O=1
|  Appearance = Colorless liquid
|  Density = 0.786 g/cm<sup>3</sup> (20 °C)
|  Solubility = [[miscible]]
|  SolubleOther = miscible in [[benzene]], [[chloroform]], [[ethanol]], [[ether]], [[glycerin]] <br> soluble in [[acetone]] <br> insoluble in [[salt]] solutions
|   MeltingPtC = −89
|  BoilingPtC = 82.6
|  pKa = 16.5<ref>{{cite journal|author=Reeve, W.; Erikson, C.M.; Aluotto, P.F. |journal=Can. J. Chem.|year=1979|volume=57|issue=20|pages= 2747|doi=10.1139/v79-444|title=A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides}}</ref>
|  Viscosity = 2.86 c[[Poise|P]] at 15 °C<br>1.96 c[[Poise|P]] at 25 °C<ref name = yaws>{{cite book | title = Chemical Properties Handbook | author = Yaws, C.L. | publisher = [[McGraw-Hill]] | year = 1999 | isbn = 0-07-073401-1}}</ref><br>1.77 c[[Poise|P]] at 30 °C<ref name = yaws/>
|   Dipole = 1.66 [[Debye|D]] (gas)
|  RefractIndex = 1.3776
  }}
| Section7 = {{Chembox Hazards
|  EU-classification = Highly flammable (F), Irritating (Xi)
|  ExternalMSDS = [http://msds.chem.ox.ac.uk/PR/2-propanol.html External MSDS]
|  MainHazards = Flammable
|  ExploLimits = 2–12.7%
|  RPhrases = {{R11}} {{R36}} {{R67}}
|  SPhrases = {{S7}} {{S16}} {{S24}} {{S25}} {{S26}}
|  GHSPictograms = {{GHS exclamation mark}} {{GHS flame}}
|  GHSSignalWord = '''Danger'''
|  HPhrases = {{H-phrases|225|319|336}}
|  PPhrases = {{P-phrases|210|261|305+351+338}}
|  NFPA-H = 1 <!--http://www.telecheminternational.com/IPA_Reagent_ACS.PDF-->
|  NFPA-F = 3
|  NFPA-R = 0
|  Autoignition = {{convert|399|C|F}}
|   FlashPt = Open cup:  {{convert|11.7|C|F}}<br>Closed cup: {{convert|13|C|F}}
|  TLV-TWA = 980 mg/m<sup>3</sup>
|  TLV-STEL = 1225 mg/m<sup>3</sup>
|  LD50 = 3600 mg/kg (oral, mouse)<br> 12800 mg/kg (dermal, rabbit)<br> [[Median lethal concentration|LC<sub>50</sub>]] = 53000 mg/m<sup>3</sup> (inhalation, mouse)
|  PEL = TWA 400 ppm (980 mg/m<sup>3</sup>)<ref>{{PGCH|0359}}</ref>
  }}
| Section8 = {{Chembox Related
|  Function = [[alcohol]]s
|  OtherFunctn = [[1-Propanol]], [[ethanol]], [[2-butanol]]
  }}
}}
|mechAction=<!--Structure-->
|structure=<!--Pharmacodynamics-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.


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<!--How Supplied-->
<!--How Supplied-->
|howSupplied=*
|packLabel=<!--Patient Counseling Information-->
|packLabel=<!--Patient Counseling Information-->
|fdaPatientInfo=apply to skin directly or with clean gauze, cotton or swab.
|fdaPatientInfo=* Apply to skin directly or with clean gauze, cotton or swab.
for rubbing, apply liberally and rub with hands.
* For rubbing, apply liberally and rub with hands.
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.


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<!--Look-Alike Drug Names-->
<!--Look-Alike Drug Names-->
|lookAlike=* A® — B®<ref name="www.ismp.org">{{Cite web  | last =  | first =  | title = http://www.ismp.org | url = http://www.ismp.org | publisher =  | date =  }}</ref>
<!--Drug Shortage Status-->
|drugShortage=
|drugShortage=
}}
}}
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[[Category:Drug]]
[[Category:Drug]]
[[Category:Alcohol solvents]]
[[Category:Oxygenates]]
[[Category:Antiseptics]]
[[Category:Disinfectants]]

Latest revision as of 16:33, 20 August 2015

Isopropyl alcohol
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.
NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Overview

Isopropyl alcohol is an antiseptic that is FDA approved for the treatment of cuts, scrapes and minor muscular aches. Common adverse reactions include hypersensitivity.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

to decrease germs in minor cuts and scrapes. helps relieve minor muscular aches due to exertion.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding FDA-Labeled Use of Isopropyl alcohol in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in pediatric patients.

Contraindications

There is limited information regarding Isopropyl alcohol Contraindications in the drug label.

Warnings

  • For external use only
  • Flammable, keep away from fire and flame will produce serious gastric disturbances if taken internally
  • Ask a doctor before use if you have deep puncture wounds or serious burns
  • When using this product do not get into eyes or mucous membranes use only in a well-ventilated area.
  • Stop use and ask a doctor if condition persists or gets worse.
  • Keep out of reach of children. In case of an accidental ingestion, contact a Poison Control Center immediately.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Isopropyl alcohol in the drug label.

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Isopropyl alcohol in the drug label.

Drug Interactions

There is limited information regarding Isopropyl alcohol Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Isopropyl alcohol in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Isopropyl alcohol during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Isopropyl alcohol with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Isopropyl alcohol with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Isopropyl alcohol with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Isopropyl alcohol with respect to specific gender populations.

Race

There is no FDA guidance on the use of Isopropyl alcohol with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Isopropyl alcohol in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Isopropyl alcohol in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Isopropyl alcohol in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Isopropyl alcohol in patients who are immunocompromised.

Administration and Monitoring

Administration

Monitoring

There is limited information regarding Monitoring of Isopropyl alcohol in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Isopropyl alcohol in the drug label.

Overdosage

There is limited information regarding Isopropyl alcohol overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

Template:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox E numberTemplate:Chembox RTECSTemplate:Chembox UNNumberTemplate:Chembox AppearanceTemplate:Chembox DensityTemplate:Chembox MeltingPtTemplate:Chembox BoilingPtTemplate:Chembox SolubilityInWaterTemplate:Chembox SolubilityTemplate:Chembox pKaTemplate:Chembox RefractIndexTemplate:Chembox ViscosityTemplate:Chembox DipoleTemplate:Chembox MainHazardsTemplate:Chembox GHSPictogramsTemplate:Chembox GHSSignalWordTemplate:Chembox HPhrasesTemplate:Chembox PPhrasesTemplate:Chembox NFPATemplate:Chembox FlashPtTemplate:Chembox ExploLimitsTemplate:Chembox TLVTemplate:Chembox Lethal amounts (set)Template:Chembox NIOSH (set)Template:Chembox Supplement
Template:Chembox header2 | Isopropyl alcohol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
KEGG
UNII
Properties
C3H8O
Molar mass 60.10 g·mol−1
Hazards
Related compounds
Template:Chembox header2 | Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Mechanism of Action

There is limited information regarding Isopropyl alcohol Mechanism of Action in the drug label.

Structure

There is limited information regarding Isopropyl alcohol Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Isopropyl alcohol in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Isopropyl alcohol in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Isopropyl alcohol in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Isopropyl alcohol in the drug label.

How Supplied

There is limited information regarding Isopropyl alcohol How Supplied in the drug label.

Storage

There is limited information regarding Isopropyl alcohol Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Isopropyl alcohol |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Isopropyl alcohol |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

  • Apply to skin directly or with clean gauze, cotton or swab.
  • For rubbing, apply liberally and rub with hands.

Precautions with Alcohol

  • Alcohol-Isopropyl alcohol interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

  • ISOPROPYL RUBBING ALCOHOL®[4]

Look-Alike Drug Names

There is limited information regarding Isopropyl alcohol Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ Reeve, W.; Erikson, C.M.; Aluotto, P.F. (1979). "A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides". Can. J. Chem. 57 (20): 2747. doi:10.1139/v79-444.
  2. ↑ 2.0 2.1 Yaws, C.L. (1999). Chemical Properties Handbook. McGraw-Hill. ISBN 0-07-073401-1.
  3. ↑ Template:PGCH
  4. ↑ "ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid".

{{#subobject: 

 |Label Page=Isopropyl alcohol
 |Label Name=IPL 01.jpg

}}

{{#subobject: 

 |Label Page=Isopropyl alcohol
 |Label Name=DailyMed - ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid .png

}}

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