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{{CMG}}
==Overview==
== Causes ==
===Common Causes===
The most common causes of myalgia are overuse, [[injury]] or [[Stress (medicine)|stress]]<ref name=MedlinePlus>[http://www.nlm.nih.gov/medlineplus/ency/article/003178.htm MedlinePlus]</ref>. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes.
The most common causes of myalgia are overuse, [[injury]] or [[Stress (medicine)|stress]]<ref name=MedlinePlus>[http://www.nlm.nih.gov/medlineplus/ency/article/003178.htm MedlinePlus]</ref>. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes.


==== Overuse ====
==Causes==
===Common Causes===
*[[Bursitis]]
*[[Caveolin-3 related distal myopathy]]
*[[Delayed onset muscle soreness]]
*[[Fibromyalgia]]
*[[Hypothyroid myopathy]]
*[[Hypotonia]]
*[[Inflammatory myopathy]]
*[[Muscle abscess]]
*[[Myoadenylate deaminase deficiency]]
*[[Myopathy ]]
*[[Myositis]]
*[[Pes anserinus pain syndrome]]
*[[Physical trauma]]
*[[Polio]]
*[[Polymyositis]]
*[[Pyomyositis]]
*[[Repetitive strain injury]]
*[[Rhizomelic pseudopolyarthritis]]
*[[Rippling muscle disease ]]
*[[Tumor-induced osteomalacia]]


Overuse of a muscle is using it too much, too soon and/or too often. <ref name=MedlinePlus/> Examples are:
===Causes by Organ System===
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Cholesterol embolism]],  [[Claudication]],  [[Endocarditis]],  [[Exercise intolerance]],  [[Hemochromatosis]],  [[Polyarteritis nodosa]],  [[Vasculitis]]
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="Beige"| [[5-azacytidine]],  [[Aluminium toxicity]],  [[Arsenic trioxide]],  [[Lead]],  [[Nitrogen dioxide]],  [[Tryptophan]]
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| [[Dermatomyositis]],  [[Ehlers-danlos syndrome]],  [[Morphea]],  [[Sweet's disease]],  [[Weber-christian disease ]]
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Acetaminophen]],  [[Acrylamide]],  [[Aldara ]],  [[Amlodipine besylate ]],  [[Amphotericin b]],  [[Aromatase inhibitors]],  [[Artemether]],  [[Atorvastatin calcium trihydrate]],  [[Atovaquone]],  [[Bezafibrate]],  [[Bicalutamide]],  [[Boniva]],  [[Campylobacter jejuni]],  [[Carfilzomib]],  [[Ciprofloxacin ]],  [[Cytarabine]],  [[Dabrafenib]],  [[Darbepoetin]],  [[Desloratadine]],  [[Disoproxil fumarate]],  [[Efavirenz]],  [[Emtricitabine]],  [[Enzalutamide]],  [[Eribulin]],  [[Evolocumab]],  [[Filgastrim]],  [[Florbetapir f-18]],  [[Fulvestrant]],  [[Gemifloxacin mesylate]],  [[Glucocorticoid-induced myopathy]],  [[Hpv vaccine]],  [[Idursulfase]],  [[Imatinib mesylate]],  [[Infliximab]],  [[Interferon alfa-2b ]],  [[Interferon alpha]],  [[Interferon beta- 1a]],  [[Interferon beta- 1b]],  [[Interferon gamma]],  [[Interleukin 2]],  [[Isotretinoin]],  [[Ivacaftor]],  [[Ixabepilone]],  [[Janumet]],  [[Leflunomide]],  [[Lenvatinib]],  [[Letrozole]],  [[Levalbuterol]],  [[Linagliptin]],  [[Melarsoprol]],  [[Mifepristone]],  [[Nabilone]],  [[Nalmefene]],  [[Naltrexone]],  [[Nevirapine]],  [[Niacin]],  [[Norfloxacin]],  [[Olaratumab]],  [[Oprelvekin]],  [[Oxycodone]],  [[Paclitaxel]],  [[Pegylated interferon alfa-2a]],  [[Pentamidine isethionate]],  [[Pergolide]],  [[Pertuzumab]],  [[Pravastatin]],  [[Procainamide]],  [[Progesterone]],  [[Quinupristin]],  [[Reslizumab]],  [[Rhinovirus infection]],  [[Rifaximin]],  [[Rizatriptan]],  [[Rosuvastatin]],  [[Sertraline]],  [[Simvastatin]],  [[Sipuleucel-t]],  [[Sofosbuvir]],  [[Sonidegib]],  [[Sorafenib]],  [[Spiriva]],  [[Statins]],  [[Sumatriptan]],  [[Suxamethonium]],  [[Telbivudine]],  [[Tenofovir]],  [[Tesamorelin]],  [[Thalidomide]],  [[Trametinib dimethyl sulfoxide]],  [[Trastuzumab]],  [[Triptorelin pamoate]],  [[Valdecoxib]],  [[Vardenafil]],  [[Vytorin]],  [[Zetia]],  [[Zomig]],  [[Zonisamide]]
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| [[Adrenal insufficiency]],  [[Chronic fatigue syndrome]],  [[Hypothyroid myopathy]],  [[Thyroid disease]]
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| [[Barcoo fever]],  [[Febuxostat]],  [[Glycogenosis type 5]],  [[Glycogenosis type 7]],  [[Glycogenosis type 9d]],  [[Hemochromatosis]],  [[Muscle glycogen synthase deficiency]],  [[Norwalk gastroenteritis ]],  [[Prostatitis]],  [[Toxoplasmosis]],  [[Viral digestive infections ]]
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| [[Channelopathy]],  [[Ehlers-danlos syndrome]],  [[Glycogenosis type 5]],  [[Glycogenosis type 7]],  [[Glycogenosis type 9d]],  [[Hanac syndrome]],  [[Mercaptopropionylglycine]],  [[Muscle glycogen synthase deficiency]],  [[Myalgic encephalomyelitis]],  [[Myoadenylate deaminase deficiency]],  [[Nalp12-associated hereditary periodic fever syndrome]],  [[Phosphogylcerate mutase 2 deficiency]],  [[West nile fever]]
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| [[Babesiosis ]],  [[Blood transfusion ]],  [[Carnitine palmitoyltransferase ii deficiency]],  [[Enolase deficiency type 3 ]],  [[Enterohemorrhagic escherichia coli infection]],  [[Hematoma]],  [[Hemorrhagic fever]],  [[Hypokalemia]],  [[Lactate dehydrogenase-a deficiency]],  [[Lassa fever]],  [[Paroxysmal cold haemoglobinuria]],  [[Phosphogylcerate mutase 2 deficiency]],  [[Postoperative septicaemia ]],  [[Severe potassium deficiency]],  [[Toxemia ]],  [[Toxic shock syndrome]],  [[Viral hemorrhagic fever]],  [[Vitamin d deficiency]]
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| [[Hpv vaccine]]
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| [[Acute posterior multifocal placoid pigment ]],  [[Aids]],  [[Babesiosis ]],  [[Barcoo fever]],  [[Bartonellosis ]],  [[Benzodiazepine withdrawal]],  [[Blastomycosis ]],  [[Bornholm disease]],  [[Brucellosis]],  [[Chikungunya]],  [[Coccidioidomycosis ]],  [[Common cold]],  [[Delayed viral syndromes ]],  [[Dengue fever]],  [[Ebola]],  [[Ehrlichia ewingii]],  [[Endemic typhus]],  [[Enterohemorrhagic escherichia coli infection]],  [[Epidemic typhus ]],  [[Epstein-barr virus]],  [[Familial mediterranean fever]],  [[Filovirus ]],  [[Flavivirus ]],  [[Flu ]],  [[Granulocyte-macrophage colony stimulating factor]],  [[Hantavirus ]],  [[Heartland virus]],  [[Hemorrhagic fever]],  [[Herpes]],  [[Hibernian fever]],  [[Histoplasmosis]],  [[Hiv]],  [[Human granulocytic ehrlichiosis]],  [[Human parvovirus b19 infection ]],  [[Infectious diarrhea ]],  [[Infectious mononucleosis]],  [[Influenza]],  [[Lassa fever]],  [[Legionellosis]],  [[Leptospirosis]],  [[Lyme disease]],  [[Malaria ]],  [[Marburg virus ]],  [[Mastocytosis]],  [[Meningitis]],  [[Meningococcal disease ]],  [[Monkeypox]],  [[Muscle abscess]],  [[Pharyngitis]],  [[Pneumonia]],  [[Polio]],  [[Postoperative septicaemia ]],  [[Prostatitis]],  [[Psittacosis]],  [[Pyomyositis]],  [[Q fever ]],  [[Queensland tick typhus]],  [[Rabies]],  [[Rickettsia akari]],  [[Rickettsia siberica ]],  [[Rickettsia typhi ]],  [[Rickettsial disease ]],  [[Ricketttsialpox ]],  [[Rift valley fever]],  [[Rocky mountain spotted fever]],  [[Ross river virus]],  [[Roundworm ]],  [[Sargramostim]],  [[Schistosoma haematobium]],  [[Sepsis ]],  [[Spotted fevers ]],  [[Staphylococcal toxic shock syndrome]],  [[Staphylococcus aureus]],  [[Streptococcal infections]],  [[Tick typhus]],  [[Toxemia ]],  [[Toxic shock syndrome]],  [[Toxoplasmosis]],  [[Trichinella spiralis]],  [[Trichinosis ]],  [[Typhoid fever ]],  [[Vibrio vulnificus infection ]],  [[Viral digestive infections ]],  [[Viral hemorrhagic fever]],  [[Viral pneumonia]],  [[Weil's syndrome ]],  [[West nile encephalitis]],  [[West nile fever]],  [[Western equine encephalitis]],  [[Wuchereria bancrofti]],  [[Yellow fever]]
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| [[Bursitis]],  [[Caveolin-3 related distal myopathy]],  [[Delayed onset muscle soreness]],  [[Fibromyalgia]],  [[Hypothyroid myopathy]],  [[Hypotonia]],  [[Inflammatory myopathy]],  [[Muscle abscess]],  [[Myoadenylate deaminase deficiency]],  [[Myopathy ]],  [[Myositis]],  [[Pes anserinus pain syndrome]],  [[Polio]],  [[Polymyositis]],  [[Pyomyositis]],  [[Repetitive strain injury]],  [[Rhizomelic pseudopolyarthritis]],  [[Rippling muscle disease ]],  [[Tumor-induced osteomalacia]]
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| [[Amyotrophic lateral sclerosis, familial type 1]],  [[Chronic fatigue syndrome]],  [[Devic's disease]],  [[Eosinophilia myalgia syndrome]],  [[Mitochondrial myopathy]],  [[Mixed connective tissue disease]],  [[Multiple sclerosis]],  [[Myalgic encephalomyelitis]],  [[Optic neuropathy]],  [[Peripheral neuropathy]],  [[Pes anserinus pain syndrome]],  [[Stiff man syndrome]],  [[Sweet's disease]],  [[West nile encephalitis]],  [[Western equine encephalitis]]
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| [[Hypovitaminosis d]],  [[Phosphate diabetes ]],  [[Vitamin d deficiency]]
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| [[Tumor-induced osteomalacia]]
|-
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|bgcolor="Beige"| [[Acute posterior multifocal placoid pigment ]], [[Optic neuropathy]],  [[Stickler syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|bgcolor="Beige"| [[Alcohol withdrawal]],  [[Barbiturate withdrawal]],  [[Caffeine withdrawal]],  [[Corticosteroid withdrawal]],  [[Etidronic acid]],  [[Glucocorticoid-induced myopathy]],  [[Opiate withdrawal]]
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| [[Stress]]
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| [[Coccidioidomycosis ]],  [[Hiv]],  [[Legionellosis]],  [[Pneumonia]],  [[Sarcoidosis]],  [[Severe acute respiratory syndrome]],  [[Viral pneumonia]]
|-
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|bgcolor="Beige"| [[Haff syndrome]], [[Hypokalemia]],  [[Rhabdomyolysis]]
|-
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| [[Bursitis]],  [[Chronic exertional compartment syndrome]],  [[Dermatomyositis]],  [[Devic's disease]],  [[Eosinophilia myalgia syndrome]],  [[Febuxostat]],  [[Fibromyalgia]],  [[Hibernian fever]],  [[Inflammatory myopathy]],  [[Polyarteritis nodosa]],  [[Polymyalgia rheumatica]],  [[Polymyositis]],  [[Sarcoidosis]],  [[Stickler syndrome]],  [[Systemic lupus erythematosus]]
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| [[Aids]], [[Herpes]]
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| [[Physical trauma]], [[Repetitive strain injury]]
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|-
|}


* [[Repetitive strain injury]].
===Causes in Alphabetical Order===
{{columns-list|
*[[5-azacytidine]]
*[[Acetaminophen]]
*[[Acrylamide]]
*[[Acute posterior multifocal placoid pigment ]]
*[[Adrenal insufficiency]]
*[[Aids]]
*[[Alcohol withdrawal]]
*[[Aldara ]]
*[[Aluminium]]
*[[Aluminium toxicity]]
*[[Amlodipine besylate ]]
*[[Amphotericin b]]
*[[Amyotrophic lateral sclerosis, familial type 1]]
*[[Aromatase inhibitors]]
*[[Arsenic trioxide]]
*[[Artemether]]
*[[Atorvastatin]]
*[[Atorvastatin calcium trihydrate]]
*[[Atovaquone]]
*[[Babesiosis ]]
*[[Barbiturate withdrawal]]
*[[Barcoo fever]]
*[[Bartonellosis ]]
*[[Benzodiazepine withdrawal]]
*[[Bezafibrate]]
*[[Bicalutamide]]
*[[Blastomycosis ]]
*[[Blood transfusion ]]
*[[Boniva]]
*[[Bornholm disease]]
*[[Brucellosis]]
*[[Bursitis]]
*[[Caffeine withdrawal]]
*[[Campylobacter jejuni]]
*[[Carfilzomib]]
*[[Carnitine palmitoyltransferase ii deficiency]]
*[[Caveolin-3 related distal myopathy]]
*[[Channelopathy]]
*[[Chikungunya]]
*[[Cholesterol embolism]]
*[[Chronic exertional compartment syndrome]]
*[[Chronic fatigue syndrome]]
*[[Ciprofloxacin ]]
*[[Claudication]]
*[[Coccidioidomycosis ]]
*[[Cold]]
*[[Common cold]]
*[[Corticosteroid withdrawal]]
*[[Cytarabine]]
*[[Dabrafenib]]
*[[Darbepoetin]]
*[[Delayed onset muscle soreness]]
*[[Delayed viral syndromes ]]
*[[Dengue fever]]
*[[Dermatomyositis]]
*[[Desloratadine]]
*[[Devic's disease]]
*[[Disoproxil fumarate]]
*[[Ebola]]
*[[Efavirenz]]
*[[Ehlers-danlos syndrome]]
*[[Ehrlichia ewingii]]
*[[Emtricitabine]]
*[[Endemic typhus]]
*[[Endocarditis]]
*[[Enolase deficiency type 3 ]]
*[[Enterohemorrhagic escherichia coli infection]]
*[[Enzalutamide]]
*[[Eosinophilia myalgia syndrome]]
*[[Eosinophilia-myalgia syndrome]]
*[[Epidemic typhus ]]
*[[Epstein-barr virus]]
*[[Eribulin]]
*[[Etidronic acid]]
*[[Evolocumab]]
*[[Exercise intolerance]]
*[[Familial mediterranean fever]]
*[[Febuxostat]]
*[[Fibromyalgia]]
*[[Filgastrim]]
*[[Filovirus ]]
*[[Flavivirus ]]
*[[Florbetapir f-18]]
*[[Flu ]]
*[[Fulvestrant]]
*[[Gemifloxacin mesylate]]
*[[Glucocorticoid-induced myopathy]]
*[[Glycogenosis type 5]]
*[[Glycogenosis type 7]]
*[[Glycogenosis type 9d]]
*[[Granulocyte-macrophage colony stimulating factor]]
*[[Haff syndrome]]
*[[Hanac syndrome]]
*[[Hantavirus ]]
*[[Heartland virus]]
*[[Hematoma]]
*[[Hemochromatosis]]
*[[Hemorrhagic fever]]
*[[Herpes]]
*[[Hibernian fever]]
*[[Histoplasmosis]]
*[[Hiv]]
*[[Hpv vaccine]]
*[[Human granulocytic ehrlichiosis]]
*[[Human parvovirus b19 infection ]]
*[[Hypokalemia]]
*[[Hypothyroid myopathy]]
*[[Hypotonia]]
*[[Hypovitaminosis d]]
*[[Idursulfase]]
*[[Imatinib mesylate]]
*[[Infectious diarrhea ]]
*[[Infectious mononucleosis]]
*[[Inflammatory myopathy]]
*[[Infliximab]]
*[[Influenza]]
*[[Interferon alfa-2b ]]
*[[Interferon alpha]]
*[[Interferon beta- 1a]]
*[[Interferon beta- 1b]]
*[[Interferon gamma]]
*[[Interleukin 2]]
*[[Isotretinoin]]
*[[Ivacaftor]]
*[[Ixabepilone]]
*[[Janumet]]
*[[Lactate dehydrogenase-a deficiency]]
*[[Lassa fever]]
*[[Lead]]
*[[Leflunomide]]
*[[Legionellosis]]
*[[Lenvatinib]]
*[[Leptospirosis]]
*[[Letrozole]]
*[[Levalbuterol]]
*[[Linagliptin]]
*[[Lyme disease]]
*[[Malaria ]]
*[[Marburg virus ]]
*[[Mastocytosis]]
*[[Melarsoprol]]
*[[Meningitis]]
*[[Meningococcal disease ]]
*[[Mercaptopropionylglycine]]
*[[Mifepristone]]
*[[Mitochondrial myopathy]]
*[[Mixed connective tissue disease]]
*[[Monkeypox]]
*[[Morphea]]
*[[Multiple sclerosis]]
*[[Muscle abscess]]
*[[Muscle glycogen synthase deficiency]]
*[[Myalgic encephalomyelitis]]
*[[Myoadenylate deaminase deficiency]]
*[[Myopathy ]]
*[[Myositis]]
*[[Nabilone]]
*[[Nalmefene]]
*[[Nalp12-associated hereditary periodic fever syndrome]]
*[[Naltrexone]]
*[[Nevirapine]]
*[[Niacin]]
*[[Nitrogen dioxide]]
*[[Norfloxacin]]
*[[Norwalk gastroenteritis ]]
*[[Olaratumab]]
*[[Opiate withdrawal]]
*[[Oprelvekin]]
*[[Optic neuropathy]]
*[[Oxycodone]]
*[[Paclitaxel]]
*[[Paroxysmal cold haemoglobinuria]]
*[[Pegylated interferon alfa-2a]]
*[[Pentamidine isethionate]]
*[[Pergolide]]
*[[Peripheral neuropathy]]
*[[Pertuzumab]]
*[[Pes anserinus pain syndrome]]
*[[Pharyngitis]]
*[[Phosphate diabetes ]]
*[[Phosphogylcerate mutase 2 deficiency]]
*[[Physical trauma]]
*[[Pneumonia]]
*[[Polio]]
*[[Polyarteritis nodosa]]
*[[Polymyalgia rheumatica]]
*[[Polymyositis]]
*[[Postoperative septicaemia ]]
*[[Pravastatin]]
*[[Procainamide]]
*[[Progesterone]]
*[[Prostatitis]]
*[[Psittacosis]]
*[[Pyomyositis]]
*[[Q fever ]]
*[[Queensland tick typhus]]
*[[Quinupristin]]
*[[Rabies]]
*[[Repetitive strain injury]]
*[[Reslizumab]]
*[[Rhabdomyolysis]]
*[[Rhinovirus infection]]
*[[Rhizomelic pseudopolyarthritis]]
*[[Rickettsia akari]]
*[[Rickettsia siberica ]]
*[[Rickettsia typhi ]]
*[[Rickettsial disease ]]
*[[Ricketttsialpox ]]
*[[Rifaximin]]
*[[Rift valley fever]]
*[[Rippling muscle disease ]]
*[[Rizatriptan]]
*[[Rocky mountain spotted fever]]
*[[Ross river virus]]
*[[Rosuvastatin]]
*[[Roundworm ]]
*[[Sarcoidosis]]
*[[Sargramostim]]
*[[Schistosoma haematobium]]
*[[Sepsis ]]
*[[Sertraline]]
*[[Severe acute respiratory syndrome]]
*[[Severe potassium deficiency]]
*[[Simvastatin]]
*[[Sipuleucel-t]]
*[[Sofosbuvir]]
*[[Sonidegib]]
*[[Sorafenib]]
*[[Spiriva]]
*[[Spotted fevers ]]
*[[Staphylococcal toxic shock syndrome]]
*[[Staphylococcus aureus]]
*[[Statins]]
*[[Stickler syndrome]]
*[[Stiff man syndrome]]
*[[Streptococcal infections]]
*[[Stress]]
*[[Sumatriptan]]
*[[Suxamethonium]]
*[[Sweet's disease]]
*[[Systemic lupus erythematosus]]
*[[Telbivudine]]
*[[Tenofovir]]
*[[Tesamorelin]]
*[[Thalidomide]]
*[[Thyroid disease]]
*[[Tick typhus]]
*[[Toxemia ]]
*[[Toxic shock syndrome]]
*[[Toxoplasmosis]]
*[[Trametinib dimethyl sulfoxide]]
*[[Trastuzumab]]
*[[Trichinella spiralis]]
*[[Trichinosis ]]
*[[Triptorelin pamoate]]
*[[Tryptophan]]
*[[Tumor-induced osteomalacia]]
*[[Typhoid fever ]]
*[[Valdecoxib]]
*[[Vardenafil]]
*[[Vasculitis]]
*[[Vibrio vulnificus infection ]]
*[[Viral digestive infections ]]
*[[Viral hemorrhagic fever]]
*[[Viral pneumonia]]
*[[Vitamin d deficiency]]
*[[Vytorin]]
*[[Weber-christian disease ]]
*[[Weil's syndrome ]]
*[[West nile encephalitis]]
*[[West nile fever]]
*[[Western equine encephalitis]]
*[[Wuchereria bancrofti]]
*[[Yellow fever]]
*[[Zetia]]
*[[Zomig]]
*[[Zonisamide]]
}}


==== Injury ====
==References==
{{reflist|2}}
{{WH}}
{{WS}}


The most common causes of myalgia by [[injury]] are: sprains and strain (injury)<ref name=MedlinePlus/>.
==== Diseases/Disorders ====
===== Infectious =====
[[Trichinosis]], [[Typhoid fever]], [[Upper respiratory tract infection]], [[Viral pneumonia]], [[Influenza]], [[Common cold]], [[Community-acquired pneumonia]], [[Coccidioidomycosis]], [[Dengue]], [[Endemic typhus]], [[HIV]], [[Infectious mononucleosis]], [[Legionellosis]], [[Leptospirosis]], [[Lyme disease]], [[Malaria]], [[Marburg virus]], [[Meningitis]], [[Monkeypox]], [[Pharyngitis]], [[Pneumonia]], [[Prostatitis]], [[Psittacosis]], [[Q fever]], [[Rabies]],  [[Rift Valley fever]], [[Severe acute respiratory syndrome]] (SARS), [[Toxic shock syndrome]], West Nile, [[Chikungunya]]
===== Autoimmune =====
[[Multiple sclerosis]], [[Myositis]], [[Lupus erythematosus]], [[Familial Mediterranean fever]], [[Polyarteritis nodosa]], [[Devic's disease]], [[Morphea]]
===== Metabolic Defect =====
[[Carnitine palmitoyltransferase II deficiency]], [[Conn's syndrome]], [[Adrenal insufficiency]]
===== Other =====
[[Chronic fatigue syndrome]], [[Hypokalemia]], [[Exercise intolerance]], [[Mastocytosis]], [[Peripheral neuropathy]], Eosinophilia myalgia syndrome, [[Fibromyalgia]], [[Barcoo Fever]], [[Delayed onset muscle soreness]]
==== Medications====
[[Acetaminophen and Oxycodone]], [[Acrylamide]], Aldara, [[Amlodipine besylate and Atorvastatin calcium trihydrate]], [[Artemether/lumefantrine]], [[Atovaquone]], [[Bicalutamide]], Boniva., [[Carfilzomib]], [[Cytarabine]], [[Darbepoetin]], [[Desloratadine]], [[Disoproxil fumarate]], [[Efavirenz]], [[Emtricitabine]], [[Enzalutamide]], [[Eribulin]], [[Etidronic acid]], [[Febuxostat]], [[Filgastrim]], [[Fulvestrant]], [[HPV Vaccine]] ([[Gardasil]]),[[Gemifloxacin mesylate]], [[Infliximab]], [[Interferon Beta- 1A]], [[Interferon beta- 1b]], [[Interferon gamma]], [[Isotretinoin]], [[Ivacaftor]], [[Ixabepilone]], [[Janumet]], [[Levalbuterol]], [[Leflunomide]], [[Letrozole]], [[Linagliptin]], [[Mifepristone]], [[Nabilone]], [[Nalmefene]], [[Naltrexone]], [[Nevirapine]], [[Niacin]], [[Oprelvekin]], [[Paclitaxel]], [[Pegylated interferon alfa-2a]], [[Pentamidine Isethionate]], [[Pergolide]], [[Pertuzumab]], [[Procainamide]], [[Progesterone]], [[Quinupristin/dalfopristin]], [[Rifaximin]], [[Rizatriptan]], [[Sargramostim]], [[Sertraline]], [[Sipuleucel-T]], [[Sofosbuvir]],[[Sorafenib]], Spiriva, [[Statins]], [[Sumatriptan]], [[Telbivudine]], [[Tenofovir]], [[Trametinib dimethyl sulfoxide]], [[Triptorelin pamoate]], [[Valdecoxib]], [[Vardenafil]], [[Vytorin]], [[Thalidomide]], Zetia, Zomig, [[Zonisamide]]
==== As a Response to Vaccination ====
A moderate occurrence (25-35%) of myalgia in recipients of [[tetanus]] [[vaccination]] is identified in the US; it presents in the large muscle groups and at the subcutaneous injection site.  When a patient returns with these symptoms (which include [[fever]], poor [[appetite]] and [[lethargy]]), a clinician who fails to notice the recent tetanus vaccination on the patient's chart is in danger of making a life-threatening misdiagnosis.
An item of note is that in heart patients using selective β<sub>1</sub>-blockers such as [[metoprolol]], incidence of myalgia after tetanus vaccination is significantly higher.
==== Withdrawal Syndromes ====
Sudden cessation of [[opioids]], [[barbiturates]], [[benzodiazepines]], or [[alcohol]] can induce myalgia.
== References ==
{{reflist|2}}
[[Category:Orthopedics]]
[[Category:Orthopedics]]
[[Category:Rheumatology]]
[[Category:Rheumatology]]
[[Category:Signs and symptoms]]
[[Category:Primary care]]
[[Category:Needs overview]]
[[Category:Needs content]]
{{WH}}
{{WS}}

Latest revision as of 22:49, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

The most common causes of myalgia are overuse, injury or stress[1]. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes.

Causes

Common Causes

Causes by Organ System

Cardiovascular Cholesterol embolism, Claudication, Endocarditis, Exercise intolerance, Hemochromatosis, Polyarteritis nodosa, Vasculitis
Chemical/Poisoning 5-azacytidine, Aluminium toxicity, Arsenic trioxide, Lead, Nitrogen dioxide, Tryptophan
Dental No underlying causes
Dermatologic Dermatomyositis, Ehlers-danlos syndrome, Morphea, Sweet's disease, Weber-christian disease 
Drug Side Effect Acetaminophen, Acrylamide, Aldara , Amlodipine besylate , Amphotericin b, Aromatase inhibitors, Artemether, Atorvastatin calcium trihydrate, Atovaquone, Bezafibrate, Bicalutamide, Boniva, Campylobacter jejuni, Carfilzomib, Ciprofloxacin , Cytarabine, Dabrafenib, Darbepoetin, Desloratadine, Disoproxil fumarate, Efavirenz, Emtricitabine, Enzalutamide, Eribulin, Evolocumab, Filgastrim, Florbetapir f-18, Fulvestrant, Gemifloxacin mesylate, Glucocorticoid-induced myopathy, Hpv vaccine, Idursulfase, Imatinib mesylate, Infliximab, Interferon alfa-2b , Interferon alpha, Interferon beta- 1a, Interferon beta- 1b, Interferon gamma, Interleukin 2, Isotretinoin, Ivacaftor, Ixabepilone, Janumet, Leflunomide, Lenvatinib, Letrozole, Levalbuterol, Linagliptin, Melarsoprol, Mifepristone, Nabilone, Nalmefene, Naltrexone, Nevirapine, Niacin, Norfloxacin, Olaratumab, Oprelvekin, Oxycodone, Paclitaxel, Pegylated interferon alfa-2a, Pentamidine isethionate, Pergolide, Pertuzumab, Pravastatin, Procainamide, Progesterone, Quinupristin, Reslizumab, Rhinovirus infection, Rifaximin, Rizatriptan, Rosuvastatin, Sertraline, Simvastatin, Sipuleucel-t, Sofosbuvir, Sonidegib, Sorafenib, Spiriva, Statins, Sumatriptan, Suxamethonium, Telbivudine, Tenofovir, Tesamorelin, Thalidomide, Trametinib dimethyl sulfoxide, Trastuzumab, Triptorelin pamoate, Valdecoxib, Vardenafil, Vytorin, Zetia, Zomig, Zonisamide
Ear Nose Throat No underlying causes
Endocrine Adrenal insufficiency, Chronic fatigue syndrome, Hypothyroid myopathy, Thyroid disease
Environmental No underlying causes
Gastroenterologic Barcoo fever, Febuxostat, Glycogenosis type 5, Glycogenosis type 7, Glycogenosis type 9d, Hemochromatosis, Muscle glycogen synthase deficiency, Norwalk gastroenteritis , Prostatitis, Toxoplasmosis, Viral digestive infections 
Genetic Channelopathy, Ehlers-danlos syndrome, Glycogenosis type 5, Glycogenosis type 7, Glycogenosis type 9d, Hanac syndrome, Mercaptopropionylglycine, Muscle glycogen synthase deficiency, Myalgic encephalomyelitis, Myoadenylate deaminase deficiency, Nalp12-associated hereditary periodic fever syndrome, Phosphogylcerate mutase 2 deficiency, West nile fever
Hematologic Babesiosis , Blood transfusion , Carnitine palmitoyltransferase ii deficiency, Enolase deficiency type 3 , Enterohemorrhagic escherichia coli infection, Hematoma, Hemorrhagic fever, Hypokalemia, Lactate dehydrogenase-a deficiency, Lassa fever, Paroxysmal cold haemoglobinuria, Phosphogylcerate mutase 2 deficiency, Postoperative septicaemia , Severe potassium deficiency, Toxemia , Toxic shock syndrome, Viral hemorrhagic fever, Vitamin d deficiency
Iatrogenic Hpv vaccine
Infectious Disease Acute posterior multifocal placoid pigment , Aids, Babesiosis , Barcoo fever, Bartonellosis , Benzodiazepine withdrawal, Blastomycosis , Bornholm disease, Brucellosis, Chikungunya, Coccidioidomycosis , Common cold, Delayed viral syndromes , Dengue fever, Ebola, Ehrlichia ewingii, Endemic typhus, Enterohemorrhagic escherichia coli infection, Epidemic typhus , Epstein-barr virus, Familial mediterranean fever, Filovirus , Flavivirus , Flu , Granulocyte-macrophage colony stimulating factor, Hantavirus , Heartland virus, Hemorrhagic fever, Herpes, Hibernian fever, Histoplasmosis, Hiv, Human granulocytic ehrlichiosis, Human parvovirus b19 infection , Infectious diarrhea , Infectious mononucleosis, Influenza, Lassa fever, Legionellosis, Leptospirosis, Lyme disease, Malaria , Marburg virus , Mastocytosis, Meningitis, Meningococcal disease , Monkeypox, Muscle abscess, Pharyngitis, Pneumonia, Polio, Postoperative septicaemia , Prostatitis, Psittacosis, Pyomyositis, Q fever , Queensland tick typhus, Rabies, Rickettsia akari, Rickettsia siberica , Rickettsia typhi , Rickettsial disease , Ricketttsialpox , Rift valley fever, Rocky mountain spotted fever, Ross river virus, Roundworm , Sargramostim, Schistosoma haematobium, Sepsis , Spotted fevers , Staphylococcal toxic shock syndrome, Staphylococcus aureus, Streptococcal infections, Tick typhus, Toxemia , Toxic shock syndrome, Toxoplasmosis, Trichinella spiralis, Trichinosis , Typhoid fever , Vibrio vulnificus infection , Viral digestive infections , Viral hemorrhagic fever, Viral pneumonia, Weil's syndrome , West nile encephalitis, West nile fever, Western equine encephalitis, Wuchereria bancrofti, Yellow fever
Musculoskeletal/Orthopedic Bursitis, Caveolin-3 related distal myopathy, Delayed onset muscle soreness, Fibromyalgia, Hypothyroid myopathy, Hypotonia, Inflammatory myopathy, Muscle abscess, Myoadenylate deaminase deficiency, Myopathy , Myositis, Pes anserinus pain syndrome, Polio, Polymyositis, Pyomyositis, Repetitive strain injury, Rhizomelic pseudopolyarthritis, Rippling muscle disease , Tumor-induced osteomalacia
Neurologic Amyotrophic lateral sclerosis, familial type 1, Chronic fatigue syndrome, Devic's disease, Eosinophilia myalgia syndrome, Mitochondrial myopathy, Mixed connective tissue disease, Multiple sclerosis, Myalgic encephalomyelitis, Optic neuropathy, Peripheral neuropathy, Pes anserinus pain syndrome, Stiff man syndrome, Sweet's disease, West nile encephalitis, Western equine encephalitis
Nutritional/Metabolic Hypovitaminosis d, Phosphate diabetes , Vitamin d deficiency
Obstetric/Gynecologic No underlying causes
Oncologic Tumor-induced osteomalacia
Ophthalmologic Acute posterior multifocal placoid pigment , Optic neuropathy, Stickler syndrome
Overdose/Toxicity Alcohol withdrawal, Barbiturate withdrawal, Caffeine withdrawal, Corticosteroid withdrawal, Etidronic acid, Glucocorticoid-induced myopathy, Opiate withdrawal
Psychiatric Stress
Pulmonary Coccidioidomycosis , Hiv, Legionellosis, Pneumonia, Sarcoidosis, Severe acute respiratory syndrome, Viral pneumonia
Renal/Electrolyte Haff syndrome, Hypokalemia, Rhabdomyolysis
Rheumatology/Immunology/Allergy Bursitis, Chronic exertional compartment syndrome, Dermatomyositis, Devic's disease, Eosinophilia myalgia syndrome, Febuxostat, Fibromyalgia, Hibernian fever, Inflammatory myopathy, Polyarteritis nodosa, Polymyalgia rheumatica, Polymyositis, Sarcoidosis, Stickler syndrome, Systemic lupus erythematosus
Sexual Aids, Herpes
Trauma Physical trauma, Repetitive strain injury
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

References

  1. ↑ MedlinePlus

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