List of chemotherapeutic agents: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Seealso|Chemotherapy regimens}} | {{Seealso|Chemotherapy regimens}} | ||
{{CMG}}; {{AE}} {{AV}}; {{ | {{CMG}}; {{AE}} {{AV}}; {{Steven}} | ||
==Overview== | ==Overview== | ||
This is a '''list of chemotherapeutic agents''' | This is a '''list of chemotherapeutic agents''' that are known to be of use in [[chemotherapy]] for [[cancer]]. A full alphabetical listing is included after the categorical listing. | ||
The agents in this list are often combined into [[chemotherapy regimens]] for polychemotherapy (combination chemotherapy) | The agents in this list are often combined into [[chemotherapy regimens]] for polychemotherapy (combination chemotherapy). | ||
== Chemotherapeutic Agents by Category == | |||
=== Alkylating agents === | |||
====== Nitrogen mustards ====== | |||
* [[Chlorambucil|Chlorambucil (Leukeran)]] | |||
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]] | |||
* [[Estramustine |Estramustine (Emcyt)]] | |||
* [[Ifosfamide|Ifosfamide (Iflex)]] | |||
* [[Melphalan|Melphalan (Alkeran)]] | |||
* [[Mechlorethamine|Mechlorethamine (Mustargen)]] | |||
====== Ethylenimines ====== | |||
* [[Thiotepa|Thiotepa (Tepadina)]] | |||
====== Methylhydrazines ====== | |||
* [[Procarbazine|Procarbazine (Matulane)]] | |||
====== Alkylsulfonates ====== | |||
* [[Busulfan|Busulfan (Myleran)]] | |||
====== Nitrosoureas ====== | |||
* [[Bendamustine|Bendamustine (Treanda)]] | |||
* [[Carmustine|Carmustine (BiCNU)]] | |||
* [[Lomustine|Lomustine (CeeNU)]] | |||
* [[Streptozocin|Streptozocin (Zanosar)]] | |||
== | ====== Triazenes ====== | ||
* [[Altretamine|Altretamine (Hexalen)]] | |||
* [[Dacarbazine|Dacarbazine (Dtic-Dome)]] | |||
* [[Temozolomide|Temozolomide (Temodar)]] | |||
====== Platinum coordination complexes ====== | |||
* [[Carboplatin|Carboplatin (Paraplatin)]] | |||
* [[Cisplatin|Cisplatin (Platinol)]] | |||
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]] | |||
---- | |||
===== | === Antimetabolites === | ||
===== | ====== Folic acid analogs ====== | ||
*[[ | * [[Methotrexate|Methotrexate (Mexate, Folex)]] | ||
* [[Pemetrexed|Pemetrexed (Alimta)]] | |||
* [[Pralatrexate|Pralatrexate (Folotyn)]] | |||
===== | ====== Pyrimidine analogs ====== | ||
*[[ | * [[Azacytidine|Azacytidine (Vidaza)]] | ||
* [[Capecitabine|Capecitabine (Xeloda)]] | |||
* [[Cytarabine|Cytarabine (Cytosar)]] | |||
* [[Decitabine|Decitabine (Dacogen)]] | |||
* [[Floxuridine|Floxuridine (FUDR)]] | |||
* [[Fluorouracil|Fluorouracil (Adrucil, Efudex)]] | |||
* [[Gemcitabine|Gemcitabine (Gemzar)]] | |||
* [[Raltitrexed|Raltitrexed (Tomudex)]] | |||
===== | ====== Purine analogs ====== | ||
*[[ | * [[Cladribine|Cladribine (Leustatin)]] | ||
* [[Clofarabine|Clofarabine (Clolar)]] | |||
* [[Fludarabine|Fludarabine (Fludara)]] | |||
* [[Mercaptopurine|Mercaptopurine (Purinethol)]] | |||
* [[Nelarabine|Nelarabine (Arranon)]] | |||
* [[Pentostatin|Pentostatin (Nipent)]] | |||
* [[Thioguanine|Thioguanine (Tabloid)]] | |||
===== | ====== Ribonucleotide reductase inhibitors ====== | ||
*[[ | * [[Hydroxyurea|Hydroxyurea (Hydrea)]] | ||
---- | |||
=== | === Natural products === | ||
===== | ====== Vinca alkaloids ====== | ||
* [[Vinblastine|Vinblastine (Velban, Velsar)]] | |||
* [[Vincristine|Vincristine (Oncovin, Vincasar)]] | |||
* [[Vincristine liposome|Vincristine liposome (Marqibo)]] | |||
* [[Vinflunine|Vinflunine (Javlor)]] | |||
* [[Vinorelbine|Vinorelbine (Navelbine)]] | |||
===== | ====== Taxanes ====== | ||
* [[Docetaxel|Docetaxel (Taxotere)]] | |||
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]] | |||
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]] | |||
===== | ====== Epipodophyllotoxins ====== | ||
* [[Etoposide|Etoposide (Vespid)]] | |||
* [[Teniposide|Teniposide (Vumon)]] | |||
===== | ====== Camptothecins ====== | ||
*[[Irinotecan | * [[Irinotecan|Irinotecan (Camptosar)]] | ||
* [[Topotecan|Topotecan (Hycamtin)]] | |||
===== | ====== Antineoplastic antibiotics ====== | ||
* [[Bleomycin|Bleomycin (Blenoxane)]] | |||
* [[Dactinomycin|Dactinomycin (Cosmegen)]] | |||
* [[Daunorubicin |Daunorubicin (Cerubidine)]] | |||
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]] | |||
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]] | |||
* [[Epirubicin|Epirubicin (Ellence)]] | |||
* [[Idarubicin|Idarubicin (Idamycin)]] | |||
* [[Mitomycin C|Mitomycin C (Mutamycin)]] | |||
* [[Mitoxantrone|Mitoxantrone (Novantrone)]] | |||
* [[Pixantrone|Pixantrone (Pixuvri)]] | |||
* [[Plicamycin|Plicamycin (Mithracin)]] | |||
* [[Valrubicin|Valrubicin (Valstar)]] | |||
====== Antineoplastic enzymes ====== | |||
* [[L-Asparaginase|L-Asparaginase (Elspar)]] | |||
* [[Pegaspargase|Pegaspargase (Oncaspar)]] | |||
* [[Glucarpidase|Glucarpidase (Voraxaze)]] | |||
---- | ---- | ||
=== Hormones and Antagonists === | |||
====== Adrenocortical suppressants ====== | |||
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]] | |||
* [[Mitotane|Mitotane (Lysodren)]] | |||
* [[Trilostane|Trilostane (Modrenal)]] | |||
====== Glucocorticoids ====== | |||
* [[Dexamethasone|Dexamethasone (Decadron)]] | |||
* [[Prednisone|Prednisone (Deltasone)]] | |||
====== Progestins ====== | |||
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]] | |||
* [[Megestrol|Megestrol (Megace)]] | |||
====== Estrogens ====== | |||
* [[Esterified estrogens|Esterified estrogens (Menest)]] | |||
====== Anti-estrogens ====== | |||
* [[Fulvestrant|Fulvestrant (Faslodex)]] | |||
* [[Raloxifene|Raloxifene (Evista)]] | |||
* [[Tamoxifen|Tamoxifen (Nolvadex)]] | |||
* [[Toremifene|Toremifene (Fareston)]] | |||
====== Aromatase inhibitors ====== | |||
* [[Anastrozole|Anastrozole (Arimidex)]] | |||
* [[Exemestane|Exemestane (Aromasin)]] | |||
* [[Formestane|Formestane (Lentaron)]] | |||
* [[Letrozole|Letrozole (Femara)]] | |||
====== Androgens ====== | |||
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]] | |||
* [[Testolactone|Testolactone (Teslac)]] | |||
===== | ====== Anti-androgens ====== | ||
* [[Abarelix|Abarelix (Plenaxis)]] | |||
* [[Abiraterone|Abiraterone (Zytiga)]] | * [[Abiraterone|Abiraterone (Zytiga)]] | ||
* [[Bicalutamide|Bicalutamide (Casodex)]] | * [[Bicalutamide|Bicalutamide (Casodex)]] | ||
* [[Enzalutamide|Enzalutamide (Xtandi)]] | * [[Enzalutamide|Enzalutamide (Xtandi)]] | ||
* [[Flutamide|Flutamide (Eulexin)]] | |||
* [[Flutamide|Flutamide (Eulexin | |||
* [[Nilutamide|Nilutamide (Nilandron)]] | * [[Nilutamide|Nilutamide (Nilandron)]] | ||
====== LHRH agonists ====== | |||
* [[Triptorelin|Triptorelin (Trelstar)]] | * [[Triptorelin|Triptorelin (Trelstar)]] | ||
===== | ===== GnRH agonists ===== | ||
* [[ | * [[Buserelin|Buserelin (Superfact)]] | ||
* [[ | * [[Goserelin|Goserelin (Zoladex)]] | ||
* [[ | * [[Leuprolide|Leuprolide (Lupron)]] | ||
* [[ | |||
===== GnRH antagonists ===== | |||
* [[Degarelix|Degarelix (Firmagon)]] | |||
---- | |||
=== Biologics === | |||
===== | ===== Monoclonal antibodies ===== | ||
===== | ====== Anti-CD3 antibodies ====== | ||
* [[Catumaxomab|Catumaxomab (Removab)]] | |||
===== | ====== Anti-CD3 & anti-CD19 antibodies ====== | ||
* [[ | * [[Blinatumomab|Blinatumomab (Blincyto)]] | ||
===== | ====== Anti-CD20 antibodies ====== | ||
*[[ | * [[Rituximab|Rituximab (Rituxan)]] | ||
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin))]] | |||
* [[Obinutuzumab|Obinutuzumab (Gazyva)]] | |||
* [[Ofatumumab|Ofatumumab (Arzerra)]] | |||
* [[Tositumomab|Tositumomab (Bexxar)]] | |||
===== | ====== Anti-CD30 antibodies ====== | ||
* [[Brentuximab|Brentuximab (Adcetris)]] | |||
===== | ====== Anti-CD33 antibodies ====== | ||
* [[Gemtuzumab|Gemtuzumab (Mylotarg)]] | |||
- | ====== Anti-CD52 antibodies ====== | ||
* [[Alemtuzumab|Alemtuzumab (Campath)]] | |||
====== Anti-CTLA–4 antibodies ====== | |||
* [[Ipilimumab|Ipilimumab (Yervoy)]] | |||
===== | ====== Anti-EGFR (ErbB1) antibodies ====== | ||
*[[ | * [[Cetuximab|Cetuximab (Erbitux)]] | ||
* [[Panitumumab|Panitumumab (Vectibix)]] | |||
*[[ | |||
===== | ====== Anti-PD–1 antibodies ====== | ||
* [[Nivolumab |Nivolumab (Opdivo)]] | |||
* [[Pembrolizumab|Pembrolizumab (Keytruda)]] | |||
===== Anti-HER2 | ====== Anti-HER2/neu (ErbB2) antibodies ====== | ||
* [[Ado-trastuzumab emtansine|Ado-trastuzumab (Kadcyla)]] | |||
* [[Pertuzumab|Pertuzumab (Perjeta)]] | |||
* [[Trastuzumab|Trastuzumab (Herceptin)]] | |||
===== | ====== Anti-VEGF antibodies ====== | ||
* [[ | * [[Bevacizumab|Bevacizumab (Avastin)]] | ||
* [[Ramucirumab|Ramucirumab (Cyramza)]] | |||
===== IL-6 inhibitors ===== | ===== IL-6 inhibitors ===== | ||
*[[Siltuximab|Siltuximab (Sylvant)]] | * [[Siltuximab|Siltuximab (Sylvant)]] | ||
* [[Tocilizumab|Tocilizumab (Actemra)]] | |||
===== | ===== Immunotherapy ===== | ||
* [[Aldesleukin|Aldesleukin (Proleukin)]] | |||
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]] | * [[Denileukin diftitox|Denileukin diftitox (Ontak)]] | ||
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]] | |||
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]] | |||
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]] | |||
* [[ | |||
* [[ | |||
---- | ---- | ||
=== Hematopoietic Growth Factors === | |||
===== Erythrocyte growth factors ===== | ===== Erythrocyte growth factors ===== | ||
* [[Erythropoietin|Erythropoietin (Procrit)]] | |||
===== Granulocyte growth factors ===== | ===== Granulocyte growth factors ===== | ||
*[[Filgrastim|Filgrastim ( | * [[Filgrastim|Filgrastim (Neupogen)]] | ||
*[[Sargramostim|Sargramostin (Leukine)]] | * [[Pegfilgrastim|Pegfilgrastim (Neulasta)]] | ||
*[[Tbo-filgrastim|Tbo-filgrastim (Granix)]] | * [[Plerixafor|Plerixafor (Mozobil)]] | ||
* [[Sargramostim|Sargramostin (Leukine, Leukomax)]] | |||
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]] | |||
===== Megakaryocyte growth factors ===== | ===== Megakaryocyte growth factors ===== | ||
* [[Eltrombopag|Eltrombopag (Promacta)]] | * [[Eltrombopag|Eltrombopag (Promacta)]] | ||
* [[ | * [[Oprelvekin|Oprelvekin (Neumega)]] | ||
---- | ---- | ||
=== Supportive Medications === | |||
===== Chemotherapy protective agents ===== | ===== Chemotherapy protective agents ===== | ||
*[[Amifostine|Amifostine (Ethyol)]] | * [[Amifostine|Amifostine (Ethyol)]] | ||
*[[Cyanocobalamin|Cyanocobalamin]] | * [[Cyanocobalamin|Cyanocobalamin (Cobal)]] | ||
*[[Dexrazoxane|Dexrazoxane (Zinecard)]] | * [[Dexrazoxane|Dexrazoxane (Zinecard)]] | ||
*[[Folinic acid|Folinic acid (Leucovorin)]] | * [[Folinic acid|Folinic acid (Leucovorin Calcium)]] | ||
*[[Glucarpidase|Glucarpidase (Voraxaze)]] | * [[Glucarpidase|Glucarpidase (Voraxaze)]] | ||
*[[Levoleucovorin|Levoleucovorin (Fusilev)]] | * [[Levoleucovorin|Levoleucovorin (Fusilev)]] | ||
*[[Mesna|Mesna (Mesnex)]] | * [[Mesna|Mesna (Mesnex)]] | ||
* [[Rasburicase|Rasburicase (Elitek)]] | |||
===== Antiemetic agents ===== | ===== Antiemetic agents ===== | ||
*[[Netupitant and palonosetron |Netupitant and palonosetron (Akynzeo)]] | * [[Netupitant and palonosetron |Netupitant and palonosetron (Akynzeo)]] | ||
===== RANK ligand inhibitors ===== | ===== RANK ligand inhibitors ===== | ||
* [[Denosumab|Denosumab (Xgeva)]] | * [[Denosumab|Denosumab (Xgeva)]] | ||
===== Calcium regulators ===== | |||
* [[Gallium nitrate|Gallium nitrate (Ganite)]] | |||
* [[Pamidronate|Pamidronate (Aredia)]] | |||
* [[Zoledronic Acid|Zoledronic Acid (Zometa)]] | |||
---- | ---- | ||
=== Miscellaneous === | |||
===== | ===== Mitotic inhibitors ===== | ||
*[[ | * [[Amsacrine|Amsacrine (Amsidine)]] | ||
*[[ | * [[Cabazitaxel|Cabazitaxel (Jevtana)]] | ||
* [[Eribulin|Eribulin (Halaven)]] | |||
* [[Ixabepilone|Ixabepilone (Ixempra)]] | |||
===== HDAC inhibitors ===== | ===== HDAC inhibitors ===== | ||
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* [[Vorinostat|Vorinostat (Zolinza)]] | * [[Vorinostat|Vorinostat (Zolinza)]] | ||
===== | ===== Hedgehog pathway inhibitors ===== | ||
* [[ | * [[Vismodegib|Vismodegib (Erivedge)]] | ||
===== Immunomodulatory drugs (IMiDs) ===== | |||
* [[Lenalidomide|Lenalidomide (Revlimid)]] | |||
* [[Pomalidomide|Pomalidomide (Pomalyst)]] | |||
* [[Sipuleucel-T|Sipuleucel-T (Provenge)]] | |||
* [[Thalidomide|Thalidomide (Thalomid)]] | |||
===== Kinase inhibitors ===== | |||
* [[Afatinib|Afatinib (Gliotrif)]] | |||
* [[Axitinib|Axitinib (Inlyta)]] | |||
* [[Bosutinib|Bosutinib (Bosulif)]] | |||
* [[Cabozantinib|Cabozantinib (Cometriq)]] | |||
* [[Ceritinib|Ceritinib (Zykadia)]] | |||
* [[Crizotinib|Crizotinib (Xalkori)]] | |||
* [[Dabrafenib|Dabrafenib (Tafinlar)]] | |||
* [[Dasatinib|Dasatinib (Sprycel)]] | |||
* [[Erlotinib|Erlotinib (Tarceva)]] | |||
* [[Everolimus|Everolimus (Afinitor)]] | |||
* [[Gefitinib|Gefitinib (Iressa)]] | |||
* [[Ibrutinib|Ibrutinib (Imbruvica)]] | |||
* [[Idelalisib|Idelalisib (Zydelig)]] | |||
* [[Imatinib|Imatinib (Gleevec)]] | |||
* [[Lapatinib|Lapatinib (Tykerb)]] | |||
* [[Lenvatinib|Lenvatinib (Lenvima)]] | |||
* [[Nilotinib|Nilotinib (Tasigna)]] | |||
* [[Palbociclib|Palbociclib (Ibrance)]] | |||
* [[Regorafenib|Regorafenib (Stivarga)]] | |||
* [[Ruxolitinib|Ruxolitinib (Jakafi)]] | |||
* [[Sorafenib|Sorafenib (Nexavar)]] | |||
* [[Sunitinib|Sunitinib (Sutent)]] | |||
* [[Temsirolimus|Temsirolimus (Torisel)]] | |||
* [[Trametinib|Trametinib (Mekinist)]] | |||
* [[Vandetanib|Vandetanib (Caprelsa)]] | |||
* [[Vemurafenib|Vemurafenib (Zelboraf)]] | |||
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]] | |||
===== Photosensitizing agents ===== | |||
* [[Aminolevulinic acid |Aminolevulinic acid (Levulan)]] | |||
* [[Porfimer|Porfimer (Photofrin)]] | |||
===== Proteasome inhibitors ===== | |||
* [[Bortezomib|Bortezomib (Velcade)]] | |||
* [[Carfilzomib|Carfilzomib (Kyprolis)]] | |||
===== Radioactive agents ===== | |||
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]] | |||
===== Somatostatin analogs ===== | |||
* [[Octreotide|Octreotide (Octreotide)]] | |||
===== Differentiating agents ===== | |||
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]] | |||
* [[Bexarotene|Bexarotene (Targretin)]] | |||
* [[Tretinoin|Tretinoin (Vesanoid)]] | |||
===== Orphan drugs ===== | |||
* [[Olaparib|Olaparib (Lynparza)]] | |||
* [[Omacetaxine|Omacetaxine (Synribo)]] | |||
* [[Ranpirnase|Ranpirnase (Onconase)]] | |||
* [[Trabectedin|Trabectedin (Yondelis)]] | |||
== Chemotherapeutic Agents in Alphabetical Order == | == Chemotherapeutic Agents in Alphabetical Order == | ||
{{Columns-list|3| | |||
* [[Abarelix|Abarelix (Plenaxis)]] | |||
* [[Abiraterone|Abiraterone acetate (Zytiga)]] | * [[Abiraterone|Abiraterone acetate (Zytiga)]] | ||
* [[Ado-trastuzumab|Ado-trastuzumab emtansine (Kadcyla)]] | * [[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]] | ||
* [[Afatinib|Afatinib (Gliotrif)]] | * [[Afatinib|Afatinib (Gliotrif)]] | ||
* [[Aldesleukin|Aldesleukin (Proleukin)]] | * [[Aldesleukin|Aldesleukin (Proleukin)]] | ||
* [[Alemtuzumab|Alemtuzumab (Campath)]] | |||
* [[Altretamine|Altretamine (Hexalen)]] | * [[Altretamine|Altretamine (Hexalen)]] | ||
* [[Amifostine|Amifostine (Ethyol)]] | * [[Amifostine|Amifostine (Ethyol)]] | ||
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]] | |||
* [[Aminolevulinic acid|Aminolevulinic acid (Levulan)]] | |||
* [[Amsacrine|Amsacrine (Amsidine)]] | |||
* [[Anastrozole|Anastrozole (Arimidex)]] | * [[Anastrozole|Anastrozole (Arimidex)]] | ||
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]] | * [[Arsenic trioxide|Arsenic trioxide (Trisenox)]] | ||
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* [[Bleomycin|Bleomycin (Blenoxane)]] | * [[Bleomycin|Bleomycin (Blenoxane)]] | ||
* [[Blinatumomab|Blinatumomab (Blincyto)]] | * [[Blinatumomab|Blinatumomab (Blincyto)]] | ||
* [[Bortezomib|Bortezomib (Velcade)]] | |||
* [[Bosutinib|Bosutinib (Bosulif)]] | * [[Bosutinib|Bosutinib (Bosulif)]] | ||
* [[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]] | * [[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]] | ||
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* [[Carfilzomib|Carfilzomib (Kyprolis)]] | * [[Carfilzomib|Carfilzomib (Kyprolis)]] | ||
* [[Carmustine|Carmustine (BiCNU)]] | * [[Carmustine|Carmustine (BiCNU)]] | ||
* [[Catumaxomab|Catumaxomab (Removab)]] | |||
* [[Ceritinib|Ceritinib (Zykadia)]] | * [[Ceritinib|Ceritinib (Zykadia)]] | ||
* [[Cetuximab|Cetuximab (Erbitux)]] | * [[Cetuximab|Cetuximab (Erbitux)]] | ||
* [[Chlorambucil|Chlorambucil (Leukeran)]] | * [[Chlorambucil|Chlorambucil (Leukeran)]] | ||
* [[Cisplatin|Cisplatin (Platinol)]] | * [[Cisplatin|Cisplatin (Platinol)]] | ||
* [[Cladribine|Cladribine (Leustatin)]] | |||
* [[Clofarabine|Clofarabine (Clolar)]] | |||
* [[Crizotinib|Crizotinib (Xalkori)]] | * [[Crizotinib|Crizotinib (Xalkori)]] | ||
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]] | |||
* [[Cytarabine|Cytarabine (Cytosar)]] | |||
* [[Cytarabine liposome|Cytarabine liposome (DepoCyt)]] | |||
* [[Dabrafenib|Dabrafenib (Tafinlar)]] | * [[Dabrafenib|Dabrafenib (Tafinlar)]] | ||
* [[Dacarbazine|Dacarbazine (Dtic-Dome)]] | |||
* [[Dactinomycin|Dactinomycin (Cosmegen)]] | |||
* [[Dasatinib|Dasatinib (Sprycel)]] | * [[Dasatinib|Dasatinib (Sprycel)]] | ||
* [[Daunorubicin|Daunorubicin (Daunoxome)]] | * [[Daunorubicin|Daunorubicin (Cerubidine)]] | ||
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]] | |||
* [[Decitabine|Decitabine (Dacogen)]] | * [[Decitabine|Decitabine (Dacogen)]] | ||
* [[Degarelix|Degarelix (Firmagon)]] | * [[Degarelix|Degarelix (Firmagon)]] | ||
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* [[Docetaxel|Docetaxel (Taxotere)]] | * [[Docetaxel|Docetaxel (Taxotere)]] | ||
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]] | * [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]] | ||
* [[Doxorubicin liposome|Doxorubicin liposome (Doxil, Lipodox)]] | |||
* [[Enzalutamide|Enzalutamide (Xtandi)]] | * [[Enzalutamide|Enzalutamide (Xtandi)]] | ||
* [[Epirubicin|Epirubicin (Ellence)]] | * [[Epirubicin|Epirubicin (Ellence)]] | ||
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* [[Erlotinib|Erlotinib (Tarceva)]] | * [[Erlotinib|Erlotinib (Tarceva)]] | ||
* [[Erythropoietin|Erythropoietin (Epogen, Procrit)]] | * [[Erythropoietin|Erythropoietin (Epogen, Procrit)]] | ||
* [[Esterified estrogens|Esterified estrogens (Menest)]] | |||
* [[Estramustine|Estramustine (Emcyt)]] | * [[Estramustine|Estramustine (Emcyt)]] | ||
* [[Etoposide|Etoposide (Vespid)]] | * [[Etoposide|Etoposide (Vespid)]] | ||
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* [[Flutamide|Flutamide (Eulexin)]] | * [[Flutamide|Flutamide (Eulexin)]] | ||
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]] | * [[Folinic acid|Folinic acid (Leucovorin Calcium)]] | ||
* [[Formestane|Formestane (Lentaron)]] | |||
* [[Fulvestrant|Fulvestrant (Faslodex)]] | * [[Fulvestrant|Fulvestrant (Faslodex)]] | ||
* [[Gallium nitrate|Gallium Nitrate (Ganite)]] | * [[Gallium nitrate|Gallium Nitrate (Ganite)]] | ||
* [[Gefitinib|Gefitinib (Iressa)]] | |||
* [[Gemcitabine|Gemcitabine (Gemzar)]] | * [[Gemcitabine|Gemcitabine (Gemzar)]] | ||
* [[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]] | * [[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]] | ||
* [[Glucarpidase|Glucarpidase (Voraxaze)]] | * [[Glucarpidase|Glucarpidase (Voraxaze)]] | ||
* [[Goserelin|Goserelin Acetate (Zoladex)]] | * [[Goserelin acetate|Goserelin Acetate (Zoladex)]] | ||
* [[Hydroxyurea|Hydroxyurea (Hydrea)]] | * [[Hydroxyurea|Hydroxyurea (Hydrea)]] | ||
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]] | * [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]] | ||
Line 241: | Line 449: | ||
* [[Idelalisib|Idelalisib (Zydelig)]] | * [[Idelalisib|Idelalisib (Zydelig)]] | ||
* [[Ifosfamide|Ifosfamide (Ifex)]] | * [[Ifosfamide|Ifosfamide (Ifex)]] | ||
* [[ | * [[Imatinib|Imatinib (Gleevec)]] | ||
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]] | |||
* [[Ipilimumab|Ipilimumab (Yervoy)]] | * [[Ipilimumab|Ipilimumab (Yervoy)]] | ||
* [[Irinotecan|Irinotecan (Camptosar)]] | * [[Irinotecan|Irinotecan (Camptosar)]] | ||
* [[Ixabepilone|Ixabepilone (Ixempra)]] | * [[Ixabepilone|Ixabepilone (Ixempra)]] | ||
* [[L-Asparaginase|L-Asparaginase (Elspar)]] | * [[L-Asparaginase|L-Asparaginase (Elspar)]] | ||
Line 277: | Line 485: | ||
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]] | * [[Oxaliplatin|Oxaliplatin (Eloxatin)]] | ||
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]] | * [[Paclitaxel|Paclitaxel (Taxol, Onxol)]] | ||
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]] | |||
* [[Palbociclib|Palbociclib (Ibrance)]] | * [[Palbociclib|Palbociclib (Ibrance)]] | ||
* [[Pamidronate|Pamidronate (Aredia)]] | * [[Pamidronate|Pamidronate (Aredia)]] | ||
* [[Panitumumab|Panitumumab (Vectibix)]] | * [[Panitumumab|Panitumumab (Vectibix)]] | ||
* [[Pazopanib|Pazopanib (Votrient)]] | * [[Pazopanib|Pazopanib (Votrient)]] | ||
* [[Pegaspargase| | * [[Pegaspargase|Pegaspargase (Oncaspar)]] | ||
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]] | * [[Pegfilgrastim|Pegfilgrastim (Neulasta)]] | ||
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]] | |||
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]] | * [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]] | ||
* [[Pembrolizumab|Pembrolizumab (Keytruda)]] | * [[Pembrolizumab|Pembrolizumab (Keytruda)]] | ||
Line 288: | Line 498: | ||
* [[Pentostatin|Pentostatin (Nipent)]] | * [[Pentostatin|Pentostatin (Nipent)]] | ||
* [[Pertuzumab|Pertuzumab (Perjeta)]] | * [[Pertuzumab|Pertuzumab (Perjeta)]] | ||
* [[Pixantrone|Pixantrone (Pixuvri)]] | |||
* [[Plerixafor|Plerixafor (Mozobil)]] | * [[Plerixafor|Plerixafor (Mozobil)]] | ||
* [[Plicamycin|Plicamycin (Mithracin)]] | |||
* [[Pomalidomide|Pomalidomide (Pomalyst)]] | * [[Pomalidomide|Pomalidomide (Pomalyst)]] | ||
* [[Ponatinib|Ponatinib (Iclusig)]] | * [[Ponatinib|Ponatinib (Iclusig)]] | ||
* [[Porfimer|Porfimer (Photofrin)]] | |||
* [[Pralatrexate|Pralatrexate (Folotyn)]] | * [[Pralatrexate|Pralatrexate (Folotyn)]] | ||
* [[Prednisone|Prednisone (Deltasone)]] | * [[Prednisone|Prednisone (Deltasone)]] | ||
* [[Procarbazine|Procarbazine (Matulane)]] | * [[Procarbazine|Procarbazine (Matulane)]] | ||
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]] | * [[Radium-223 chloride|Radium-223 chloride (Xofigo)]] | ||
* [[Raloxifene|Raloxifene (Evista)]] | |||
* [[Raltitrexed|Raltitrexed (Tomudex)]] | |||
* [[Ramucirumab|Ramucirumab (Cyramza)]] | * [[Ramucirumab|Ramucirumab (Cyramza)]] | ||
* [[Ranpirnase|Ranpirnase (Onconase)]] | |||
* [[Rasburicase|Rasburicase (Elitek)]] | * [[Rasburicase|Rasburicase (Elitek)]] | ||
* [[Regorafenib|Regorafenib (Stivarga)]] | * [[Regorafenib|Regorafenib (Stivarga)]] | ||
Line 312: | Line 528: | ||
* [[Temsirolimus|Temsirolimus (Torisel)]] | * [[Temsirolimus|Temsirolimus (Torisel)]] | ||
* [[Teniposide|Teniposide (Vumon)]] | * [[Teniposide|Teniposide (Vumon)]] | ||
* [[Testolactone|Testolactone (Teslac)]] | |||
* [[Thalidomide|Thalidomide (Thalomid)]] | * [[Thalidomide|Thalidomide (Thalomid)]] | ||
* [[Thioguanine|Thioguanine (Tabloid)]] | * [[Thioguanine|Thioguanine (Tabloid)]] | ||
* [[Thiotepa|Thiotepa ( | * [[Thiotepa|Thiotepa (Tepadina)]] | ||
* [[Tocilizumab|Tocilizumab (Actemra)]] | * [[Tocilizumab|Tocilizumab (Actemra)]] | ||
* [[Topotecan|Topotecan (Hycamtin)]] | * [[Topotecan|Topotecan (Hycamtin)]] | ||
* [[Toremifene|Toremifene (Fareston)]] | * [[Toremifene|Toremifene (Fareston)]] | ||
* [[Tositumomab|Tositumomab (Bexxar)]] | |||
* [[Trabectedin|Trabectedin (Yondelis)]] | |||
* [[Trametinib|Trametinib (Mekinist)]] | * [[Trametinib|Trametinib (Mekinist)]] | ||
* [[Trastuzumab|Trastuzumab (Herceptin)]] | * [[Trastuzumab|Trastuzumab (Herceptin)]] | ||
* [[Tretinoin|Tretinoin (Vesanoid)]] | * [[Tretinoin|Tretinoin (Vesanoid)]] | ||
* [[Triptorelin|Triptorelin (Trelstar)]] | * [[Trilostane|Trilostane (Modrenal)]] | ||
* [[Triptorelin pamoate|Triptorelin pamoate (Trelstar)]] | |||
* [[Valrubicin|Valrubicin (Valstar)]] | |||
* [[Vandetanib|Vandetanib (Caprelsa)]] | * [[Vandetanib|Vandetanib (Caprelsa)]] | ||
* [[Vemurafenib|Vemurafenib (Zelboraf)]] | * [[Vemurafenib|Vemurafenib (Zelboraf)]] | ||
* [[Vinblastine|Vinblastine (Velban, Velsar)]] | * [[Vinblastine|Vinblastine (Velban, Velsar)]] | ||
* [[Vincristine|Vincristine (Oncovin, Vincasar)]] | * [[Vincristine|Vincristine (Oncovin, Vincasar)]] | ||
* [[Vincristine | * [[Vincristine liposome|Vincristine liposome (Marqibo)]] | ||
* [[Vinflunine|Vinflunine (Javlor)]] | |||
* [[Vinorelbine|Vinorelbine (Navelbine)]] | * [[Vinorelbine|Vinorelbine (Navelbine)]] | ||
* [[Vismodegib|Vismodegib (Erivedge)]] | * [[Vismodegib|Vismodegib (Erivedge)]] | ||
Line 332: | Line 554: | ||
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]] | * [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]] | ||
* [[Zoledronic acid|Zoledronic Acid (Zometa)]] | * [[Zoledronic acid|Zoledronic Acid (Zometa)]] | ||
}} | |||
[[Category:Chemotherapeutic agents| | [[Category:Chemotherapeutic agents| ]] |
Latest revision as of 04:08, 22 March 2015
Template:Seealso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]; Steven Bellm, M.D. [3]
Overview
This is a list of chemotherapeutic agents that are known to be of use in chemotherapy for cancer. A full alphabetical listing is included after the categorical listing.
The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy).
Chemotherapeutic Agents by Category
Alkylating agents
Nitrogen mustards
- Chlorambucil (Leukeran)
- Cyclophosphamide (Cytoxan)
- Estramustine (Emcyt)
- Ifosfamide (Iflex)
- Melphalan (Alkeran)
- Mechlorethamine (Mustargen)
Ethylenimines
Methylhydrazines
Alkylsulfonates
Nitrosoureas
Triazenes
Platinum coordination complexes
Antimetabolites
Folic acid analogs
Pyrimidine analogs
- Azacytidine (Vidaza)
- Capecitabine (Xeloda)
- Cytarabine (Cytosar)
- Decitabine (Dacogen)
- Floxuridine (FUDR)
- Fluorouracil (Adrucil, Efudex)
- Gemcitabine (Gemzar)
- Raltitrexed (Tomudex)
Purine analogs
- Cladribine (Leustatin)
- Clofarabine (Clolar)
- Fludarabine (Fludara)
- Mercaptopurine (Purinethol)
- Nelarabine (Arranon)
- Pentostatin (Nipent)
- Thioguanine (Tabloid)
Ribonucleotide reductase inhibitors
Natural products
Vinca alkaloids
- Vinblastine (Velban, Velsar)
- Vincristine (Oncovin, Vincasar)
- Vincristine liposome (Marqibo)
- Vinflunine (Javlor)
- Vinorelbine (Navelbine)
Taxanes
Epipodophyllotoxins
Camptothecins
Antineoplastic antibiotics
- Bleomycin (Blenoxane)
- Dactinomycin (Cosmegen)
- Daunorubicin (Cerubidine)
- Daunorubicin liposome (Daunoxome)
- Doxorubicin (Adriamycin, Rubex)
- Epirubicin (Ellence)
- Idarubicin (Idamycin)
- Mitomycin C (Mutamycin)
- Mitoxantrone (Novantrone)
- Pixantrone (Pixuvri)
- Plicamycin (Mithracin)
- Valrubicin (Valstar)
Antineoplastic enzymes
Hormones and Antagonists
Adrenocortical suppressants
Glucocorticoids
Progestins
Estrogens
Anti-estrogens
Aromatase inhibitors
Androgens
Anti-androgens
- Abarelix (Plenaxis)
- Abiraterone (Zytiga)
- Bicalutamide (Casodex)
- Enzalutamide (Xtandi)
- Flutamide (Eulexin)
- Nilutamide (Nilandron)
LHRH agonists
GnRH agonists
GnRH antagonists
Biologics
Monoclonal antibodies
Anti-CD3 antibodies
Anti-CD3 & anti-CD19 antibodies
Anti-CD20 antibodies
- Rituximab (Rituxan)
- Ibritumomab tiuxetan (Zevalin))
- Obinutuzumab (Gazyva)
- Ofatumumab (Arzerra)
- Tositumomab (Bexxar)
Anti-CD30 antibodies
Anti-CD33 antibodies
Anti-CD52 antibodies
Anti-CTLA–4 antibodies
Anti-EGFR (ErbB1) antibodies
Anti-PD–1 antibodies
Anti-HER2/neu (ErbB2) antibodies
Anti-VEGF antibodies
IL-6 inhibitors
Immunotherapy
- Aldesleukin (Proleukin)
- Denileukin diftitox (Ontak)
- Interferon alfa-2b (Intron A)
- Peginterferon alfa-2a (Pegasys)
- Peginterferon alfa-2b (Sylatron)
Hematopoietic Growth Factors
Erythrocyte growth factors
Granulocyte growth factors
- Filgrastim (Neupogen)
- Pegfilgrastim (Neulasta)
- Plerixafor (Mozobil)
- Sargramostin (Leukine, Leukomax)
- Tbo-filgrastim (Granix)
Megakaryocyte growth factors
Supportive Medications
Chemotherapy protective agents
- Amifostine (Ethyol)
- Cyanocobalamin (Cobal)
- Dexrazoxane (Zinecard)
- Folinic acid (Leucovorin Calcium)
- Glucarpidase (Voraxaze)
- Levoleucovorin (Fusilev)
- Mesna (Mesnex)
- Rasburicase (Elitek)
Antiemetic agents
RANK ligand inhibitors
Calcium regulators
Miscellaneous
Mitotic inhibitors
HDAC inhibitors
Hedgehog pathway inhibitors
Immunomodulatory drugs (IMiDs)
Kinase inhibitors
- Afatinib (Gliotrif)
- Axitinib (Inlyta)
- Bosutinib (Bosulif)
- Cabozantinib (Cometriq)
- Ceritinib (Zykadia)
- Crizotinib (Xalkori)
- Dabrafenib (Tafinlar)
- Dasatinib (Sprycel)
- Erlotinib (Tarceva)
- Everolimus (Afinitor)
- Gefitinib (Iressa)
- Ibrutinib (Imbruvica)
- Idelalisib (Zydelig)
- Imatinib (Gleevec)
- Lapatinib (Tykerb)
- Lenvatinib (Lenvima)
- Nilotinib (Tasigna)
- Palbociclib (Ibrance)
- Regorafenib (Stivarga)
- Ruxolitinib (Jakafi)
- Sorafenib (Nexavar)
- Sunitinib (Sutent)
- Temsirolimus (Torisel)
- Trametinib (Mekinist)
- Vandetanib (Caprelsa)
- Vemurafenib (Zelboraf)
- Ziv-aflibercept (Zaltrap)
Photosensitizing agents
Proteasome inhibitors
Radioactive agents
Somatostatin analogs
Differentiating agents
Orphan drugs
Chemotherapeutic Agents in Alphabetical Order
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