List of chemotherapeutic agents: Difference between revisions
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* [[Docetaxel|Docetaxel (Taxotere)]] | * [[Docetaxel|Docetaxel (Taxotere)]] | ||
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]] | * [[Paclitaxel|Paclitaxel (Taxol, Onxol)]] | ||
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]] | |||
====== Epipodophyllotoxins ====== | ====== Epipodophyllotoxins ====== | ||
| Line 95: | Line 96: | ||
* [[Teniposide|Teniposide (Vumon)]] | * [[Teniposide|Teniposide (Vumon)]] | ||
====== Camptothecins | ====== Camptothecins ====== | ||
* [[Irinotecan|Irinotecan (Camptosar)]] | * [[Irinotecan|Irinotecan (Camptosar)]] | ||
* [[Topotecan|Topotecan (Hycamtin)]] | * [[Topotecan|Topotecan (Hycamtin)]] | ||
| Line 110: | Line 110: | ||
* [[Mitomycin C|Mitomycin C (Mutamycin)]] | * [[Mitomycin C|Mitomycin C (Mutamycin)]] | ||
* [[Mitoxantrone|Mitoxantrone (Novantrone)]] | * [[Mitoxantrone|Mitoxantrone (Novantrone)]] | ||
* [[Pixantrone|Pixantrone (Pixuvri)]] | |||
* [[Plicamycin|Plicamycin (Mithracin)]] | * [[Plicamycin|Plicamycin (Mithracin)]] | ||
* [[Valrubicin|Valrubicin (Valstar)]] | * [[Valrubicin|Valrubicin (Valstar)]] | ||
| Line 135: | Line 136: | ||
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]] | * [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]] | ||
* [[Megestrol|Megestrol (Megace)]] | * [[Megestrol|Megestrol (Megace)]] | ||
====== Estrogens ====== | |||
* [[Esterified estrogens|Esterified estrogens (Menest)]] | |||
====== Anti-estrogens ====== | ====== Anti-estrogens ====== | ||
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* [[Anastrozole|Anastrozole (Arimidex)]] | * [[Anastrozole|Anastrozole (Arimidex)]] | ||
* [[Exemestane|Exemestane (Aromasin)]] | * [[Exemestane|Exemestane (Aromasin)]] | ||
* [[Formestane|Formestane (Lentaron)]] | |||
* [[Letrozole|Letrozole (Femara)]] | * [[Letrozole|Letrozole (Femara)]] | ||
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* [[Bevacizumab|Bevacizumab (Avastin)]] | * [[Bevacizumab|Bevacizumab (Avastin)]] | ||
* [[Ramucirumab|Ramucirumab (Cyramza)]] | * [[Ramucirumab|Ramucirumab (Cyramza)]] | ||
===== IL-6 inhibitors ===== | ===== IL-6 inhibitors ===== | ||
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===== Immunotherapy ===== | ===== Immunotherapy ===== | ||
* [[Aldesleukin|Aldesleukin (Proleukin)]] | |||
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]] | |||
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]] | * [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]] | ||
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]] | * [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]] | ||
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* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]] | * [[Pegfilgrastim|Pegfilgrastim (Neulasta)]] | ||
* [[Plerixafor|Plerixafor (Mozobil)]] | * [[Plerixafor|Plerixafor (Mozobil)]] | ||
* [[Sargramostim|Sargramostin (Leukine)]] | * [[Sargramostim|Sargramostin (Leukine, Leukomax)]] | ||
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]] | * [[Tbo-filgrastim|Tbo-filgrastim (Granix)]] | ||
===== Megakaryocyte growth factors ===== | ===== Megakaryocyte growth factors ===== | ||
* [[Eltrombopag|Eltrombopag (Promacta)]] | * [[Eltrombopag|Eltrombopag (Promacta)]] | ||
* [[Oprelvekin|Oprelvekin (Neumega)]] | |||
---- | ---- | ||
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===== RANK ligand inhibitors ===== | ===== RANK ligand inhibitors ===== | ||
* [[Denosumab|Denosumab (Xgeva)]] | * [[Denosumab|Denosumab (Xgeva)]] | ||
===== Calcium regulators ===== | |||
* [[Gallium nitrate|Gallium nitrate (Ganite)]] | |||
* [[Pamidronate|Pamidronate (Aredia)]] | |||
* [[Zoledronic Acid|Zoledronic Acid (Zometa)]] | |||
---- | ---- | ||
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* [[Eribulin|Eribulin (Halaven)]] | * [[Eribulin|Eribulin (Halaven)]] | ||
* [[Ixabepilone|Ixabepilone (Ixempra)]] | * [[Ixabepilone|Ixabepilone (Ixempra)]] | ||
===== HDAC inhibitors ===== | ===== HDAC inhibitors ===== | ||
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* [[Dasatinib|Dasatinib (Sprycel)]] | * [[Dasatinib|Dasatinib (Sprycel)]] | ||
* [[Erlotinib|Erlotinib (Tarceva)]] | * [[Erlotinib|Erlotinib (Tarceva)]] | ||
* [[Everolimus|Everolimus (Afinitor)]] | |||
* [[Gefitinib|Gefitinib (Iressa)]] | * [[Gefitinib|Gefitinib (Iressa)]] | ||
* [[Ibrutinib|Ibrutinib (Imbruvica)]] | * [[Ibrutinib|Ibrutinib (Imbruvica)]] | ||
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* [[Sorafenib|Sorafenib (Nexavar)]] | * [[Sorafenib|Sorafenib (Nexavar)]] | ||
* [[Sunitinib|Sunitinib (Sutent)]] | * [[Sunitinib|Sunitinib (Sutent)]] | ||
* [[Temsirolimus|Temsirolimus (Torisel)]] | |||
* [[Trametinib|Trametinib (Mekinist)]] | * [[Trametinib|Trametinib (Mekinist)]] | ||
* [[Vandetanib|Vandetanib (Caprelsa)]] | * [[Vandetanib|Vandetanib (Caprelsa)]] | ||
* [[Vemurafenib|Vemurafenib (Zelboraf)]] | * [[Vemurafenib|Vemurafenib (Zelboraf)]] | ||
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]] | * [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]] | ||
===== Photosensitizing agents ===== | ===== Photosensitizing agents ===== | ||
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* [[Bexarotene|Bexarotene (Targretin)]] | * [[Bexarotene|Bexarotene (Targretin)]] | ||
* [[Tretinoin|Tretinoin (Vesanoid)]] | * [[Tretinoin|Tretinoin (Vesanoid)]] | ||
===== Orphan drugs ===== | |||
* [[Olaparib|Olaparib (Lynparza)]] | |||
* [[Omacetaxine|Omacetaxine (Synribo)]] | |||
* [[Ranpirnase|Ranpirnase (Onconase)]] | |||
* [[Trabectedin|Trabectedin (Yondelis)]] | |||
== Chemotherapeutic Agents in Alphabetical Order == | == Chemotherapeutic Agents in Alphabetical Order == | ||
Latest revision as of 04:08, 22 March 2015
Template:Seealso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]; Steven Bellm, M.D. [3]
Overview
This is a list of chemotherapeutic agents that are known to be of use in chemotherapy for cancer. A full alphabetical listing is included after the categorical listing.
The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy).
Chemotherapeutic Agents by Category
Alkylating agents
Nitrogen mustards
- Chlorambucil (Leukeran)
- Cyclophosphamide (Cytoxan)
- Estramustine (Emcyt)
- Ifosfamide (Iflex)
- Melphalan (Alkeran)
- Mechlorethamine (Mustargen)
Ethylenimines
Methylhydrazines
Alkylsulfonates
Nitrosoureas
Triazenes
Platinum coordination complexes
Antimetabolites
Folic acid analogs
Pyrimidine analogs
- Azacytidine (Vidaza)
- Capecitabine (Xeloda)
- Cytarabine (Cytosar)
- Decitabine (Dacogen)
- Floxuridine (FUDR)
- Fluorouracil (Adrucil, Efudex)
- Gemcitabine (Gemzar)
- Raltitrexed (Tomudex)
Purine analogs
- Cladribine (Leustatin)
- Clofarabine (Clolar)
- Fludarabine (Fludara)
- Mercaptopurine (Purinethol)
- Nelarabine (Arranon)
- Pentostatin (Nipent)
- Thioguanine (Tabloid)
Ribonucleotide reductase inhibitors
Natural products
Vinca alkaloids
- Vinblastine (Velban, Velsar)
- Vincristine (Oncovin, Vincasar)
- Vincristine liposome (Marqibo)
- Vinflunine (Javlor)
- Vinorelbine (Navelbine)
Taxanes
Epipodophyllotoxins
Camptothecins
Antineoplastic antibiotics
- Bleomycin (Blenoxane)
- Dactinomycin (Cosmegen)
- Daunorubicin (Cerubidine)
- Daunorubicin liposome (Daunoxome)
- Doxorubicin (Adriamycin, Rubex)
- Epirubicin (Ellence)
- Idarubicin (Idamycin)
- Mitomycin C (Mutamycin)
- Mitoxantrone (Novantrone)
- Pixantrone (Pixuvri)
- Plicamycin (Mithracin)
- Valrubicin (Valstar)
Antineoplastic enzymes
Hormones and Antagonists
Adrenocortical suppressants
Glucocorticoids
Progestins
Estrogens
Anti-estrogens
Aromatase inhibitors
Androgens
Anti-androgens
- Abarelix (Plenaxis)
- Abiraterone (Zytiga)
- Bicalutamide (Casodex)
- Enzalutamide (Xtandi)
- Flutamide (Eulexin)
- Nilutamide (Nilandron)
LHRH agonists
GnRH agonists
GnRH antagonists
Biologics
Monoclonal antibodies
Anti-CD3 antibodies
Anti-CD3 & anti-CD19 antibodies
Anti-CD20 antibodies
- Rituximab (Rituxan)
- Ibritumomab tiuxetan (Zevalin))
- Obinutuzumab (Gazyva)
- Ofatumumab (Arzerra)
- Tositumomab (Bexxar)
Anti-CD30 antibodies
Anti-CD33 antibodies
Anti-CD52 antibodies
Anti-CTLA–4 antibodies
Anti-EGFR (ErbB1) antibodies
Anti-PD–1 antibodies
Anti-HER2/neu (ErbB2) antibodies
Anti-VEGF antibodies
IL-6 inhibitors
Immunotherapy
- Aldesleukin (Proleukin)
- Denileukin diftitox (Ontak)
- Interferon alfa-2b (Intron A)
- Peginterferon alfa-2a (Pegasys)
- Peginterferon alfa-2b (Sylatron)
Hematopoietic Growth Factors
Erythrocyte growth factors
Granulocyte growth factors
- Filgrastim (Neupogen)
- Pegfilgrastim (Neulasta)
- Plerixafor (Mozobil)
- Sargramostin (Leukine, Leukomax)
- Tbo-filgrastim (Granix)
Megakaryocyte growth factors
Supportive Medications
Chemotherapy protective agents
- Amifostine (Ethyol)
- Cyanocobalamin (Cobal)
- Dexrazoxane (Zinecard)
- Folinic acid (Leucovorin Calcium)
- Glucarpidase (Voraxaze)
- Levoleucovorin (Fusilev)
- Mesna (Mesnex)
- Rasburicase (Elitek)
Antiemetic agents
RANK ligand inhibitors
Calcium regulators
Miscellaneous
Mitotic inhibitors
HDAC inhibitors
Hedgehog pathway inhibitors
Immunomodulatory drugs (IMiDs)
Kinase inhibitors
- Afatinib (Gliotrif)
- Axitinib (Inlyta)
- Bosutinib (Bosulif)
- Cabozantinib (Cometriq)
- Ceritinib (Zykadia)
- Crizotinib (Xalkori)
- Dabrafenib (Tafinlar)
- Dasatinib (Sprycel)
- Erlotinib (Tarceva)
- Everolimus (Afinitor)
- Gefitinib (Iressa)
- Ibrutinib (Imbruvica)
- Idelalisib (Zydelig)
- Imatinib (Gleevec)
- Lapatinib (Tykerb)
- Lenvatinib (Lenvima)
- Nilotinib (Tasigna)
- Palbociclib (Ibrance)
- Regorafenib (Stivarga)
- Ruxolitinib (Jakafi)
- Sorafenib (Nexavar)
- Sunitinib (Sutent)
- Temsirolimus (Torisel)
- Trametinib (Mekinist)
- Vandetanib (Caprelsa)
- Vemurafenib (Zelboraf)
- Ziv-aflibercept (Zaltrap)
Photosensitizing agents
Proteasome inhibitors
Radioactive agents
Somatostatin analogs
Differentiating agents
Orphan drugs
Chemotherapeutic Agents in Alphabetical Order
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