Cimicoxib: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{SI}} | {{SI}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
'''Cimicoxib''' ('''UR-8880''' trade name '''Cimalgex''') is a [[non-steroidal anti-inflammatory drug]] (NSAID) used in [[veterinary medicine]] to treat dogs for pain and inflammation associated with [[osteoarthritis]] and for the management of pain and inflammation associated with surgery.<ref>{{cite web | url = http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/veterinary/medicines/000162/vet_med_000230.jsp&mid=WC0b01ac058008d7a8&jsenabled=true | title = European Public Assessment Report: Cimalgex (cimicoxib) | publisher = European Medicines Agency}}</ref> It acts as a [[COX-2 inhibitor]]. | '''Cimicoxib''' ('''UR-8880''' trade name '''Cimalgex''') is a [[non-steroidal anti-inflammatory drug]] (NSAID) used in [[veterinary medicine]] to treat dogs for pain and inflammation associated with [[osteoarthritis]] and for the management of pain and inflammation associated with surgery.<ref>{{cite web | url = http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/veterinary/medicines/000162/vet_med_000230.jsp&mid=WC0b01ac058008d7a8&jsenabled=true | title = European Public Assessment Report: Cimalgex (cimicoxib) | publisher = European Medicines Agency}}</ref> It acts as a [[COX-2 inhibitor]]. | ||
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[[Category:Imidazoles]] | [[Category:Imidazoles]] |
Latest revision as of 19:08, 18 August 2015
WikiDoc Resources for Cimicoxib |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Cimicoxib (UR-8880 trade name Cimalgex) is a non-steroidal anti-inflammatory drug (NSAID) used in veterinary medicine to treat dogs for pain and inflammation associated with osteoarthritis and for the management of pain and inflammation associated with surgery.[1] It acts as a COX-2 inhibitor.
Synthesis
Reaction of the imine with tosylisocyanate in the presence of potassium carbonate leads to what may be viewed as 2+3 cycloaddition of the nitrogen analogue of a ketene to form the imidazole ring.
References
- ↑ "European Public Assessment Report: Cimalgex (cimicoxib)". European Medicines Agency.
- ↑ Template:Cite doi