Tyropanoic acid: Difference between revisions
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|IUPACName=2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid | |IUPACName=2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid | ||
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==Overview== | |||
'''Tyropanoic acid''' and its salt '''sodium tyropanoate''' are [[radiocontrast]] agents used in [[cholecystography]] ([[X-ray]] diagnosis of [[gallstone]]s). Trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac.<ref>{{cite web|url=http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5611|title=PubChem CID 5611}}</ref> The molecule contains three heavy [[iodine]] atoms which obstruct X-rays in the same way as the calcium in bones to produce a visible image. After injection it is rapidly excreted into the [[bile]].<ref>{{cite journal | doi = 10.1172/JCI109755 | pmid = 7364937 | pmc=371433 | volume=65 | issue=5 | title=Inhibition of hepatic binding of thyroxine by cholecystographic agents |date=May 1980 | journal=J. Clin. Invest. | pages=1032–40}}</ref> | '''Tyropanoic acid''' and its salt '''sodium tyropanoate''' are [[radiocontrast]] agents used in [[cholecystography]] ([[X-ray]] diagnosis of [[gallstone]]s). Trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac.<ref>{{cite web|url=http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5611|title=PubChem CID 5611}}</ref> The molecule contains three heavy [[iodine]] atoms which obstruct X-rays in the same way as the calcium in bones to produce a visible image. After injection it is rapidly excreted into the [[bile]].<ref>{{cite journal | doi = 10.1172/JCI109755 | pmid = 7364937 | pmc=371433 | volume=65 | issue=5 | title=Inhibition of hepatic binding of thyroxine by cholecystographic agents |date=May 1980 | journal=J. Clin. Invest. | pages=1032–40}}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | |||
{{Contrast media}} | {{Contrast media}} | ||
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[[Category:Organoiodides]] | [[Category:Organoiodides]] | ||
[[Category:Carboxylic acids]] | [[Category:Carboxylic acids]] | ||
[[Category: | [[Category:Drug]] | ||
Latest revision as of 17:22, 20 August 2015
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| Names | |
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| IUPAC name
2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid
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| Other names
2-[[2,4,6-triiodo-3-(1-oxobutylamino)phenyl]methyl]butanoic acid
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| Identifiers | |
3D model (JSmol)
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| ECHA InfoCard | Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). |
PubChem CID
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| Properties | |
| C15H18I3NO3 | |
| Molar mass | 641.02 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Tyropanoic acid and its salt sodium tyropanoate are radiocontrast agents used in cholecystography (X-ray diagnosis of gallstones). Trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac.[1] The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones to produce a visible image. After injection it is rapidly excreted into the bile.[2]
References
- ↑ "PubChem CID 5611".
- ↑ "Inhibition of hepatic binding of thyroxine by cholecystographic agents". J. Clin. Invest. 65 (5): 1032–40. May 1980. doi:10.1172/JCI109755. PMC 371433. PMID 7364937.
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- Organoiodides
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