Tolciclate: Difference between revisions

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Tolciclate
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	D01AE19 (WHO) ;
Identifiers
CAS Number	50838-36-3 ;
PubChem CID	5506;
ChemSpider	5305 ;
UNII	T3TZ02X2AZ;
KEGG	D01384 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C20H21NOS
Molar mass	323.45 g/mol
3D model (JSmol)	Interactive image;
	SMILES Cc1cccc(c1)N(C)C(=S)Oc2ccc3c(c2)C4CCC3C4;
	InChI InChI=1S/C20H21NOS/c1-13-4-3-5-16(10-13)21(2)20(23)22-17-8-9-18-14-6-7-15(11-14)19(18)12-17/h3-5,8-10,12,14-15H,6-7,11H2,1-2H3 ; Key:CANCCLAKQQHLNK-UHFFFAOYSA-N ;
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VisualWikitext

Latest revision as of 17:18, 20 August 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tolciclate is an antifungal.^[1]^[2]

References

↑ Ryder, N. S.; Frank, I.; Dupont, M. C. (May 1986). "Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate". Antimicrobial Agents and Chemotherapy. 29 (5): 858–860. doi:10.1128/aac.29.5.858. PMC 284167. PMID 3524433.
↑ Bianchi, A.; Monti, G.; de Carneri, I. (September 1977). "Tolciclate: further antimycotic studies". Antimicrobial Agents and Chemotherapy. 12 (3): 429–430. doi:10.1128/aac.12.3.429. PMC 429931. PMID 907333.

[pmid3524433-1] Ryder, N. S.; Frank, I.; Dupont, M. C. (May 1986). "Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate". Antimicrobial Agents and Chemotherapy. 29 (5): 858–860. doi:10.1128/aac.29.5.858. PMC 284167. PMID 3524433.

[pmid907333-2] Bianchi, A.; Monti, G.; de Carneri, I. (September 1977). "Tolciclate: further antimycotic studies". Antimicrobial Agents and Chemotherapy. 12 (3): 429–430. doi:10.1128/aac.12.3.429. PMC 429931. PMID 907333.

[1]

[2]

@@ Line 5: / Line 5: @@
 | IUPAC_name =
 | image = tolciclate.png
-| image2 = Tolciclate 3D spacefill.png
+| image2 = Tolciclate_3D_spacefill.png
 | width2 = 200
 | alt2 = Space-filling model of the tolciclate molecule
@@ Line 54: / Line 54: @@
 | StdInChIKey = CANCCLAKQQHLNK-UHFFFAOYSA-N
 }}
+                     __NOTOC__
+{{SI}}
+{{CMG}}
+==Overview==
 '''Tolciclate''' is an [[Antifungal medication|antifungal]].<ref name="pmid3524433">{{ cite journal | author = Ryder, N. S.; Frank, I.; Dupont, M. C. | title = Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate | journal = Antimicrobial Agents and Chemotherapy | volume = 29 | issue = 5 | pages = 858–860 |date=May 1986 | pmid = 3524433 | pmc = 284167 | doi = 10.1128/aac.29.5.858| url = http://aac.asm.org/cgi/pmidlookup?view=long&pmid=3524433 }}</ref><ref name="pmid907333">{{ cite journal | author = Bianchi, A.; Monti, G.; de Carneri, I. | title = Tolciclate: further antimycotic studies | journal = Antimicrobial Agents and Chemotherapy | volume = 12 | issue = 3 | pages = 429–430 |date=September 1977 | pmid = 907333 | pmc = 429931 | doi = 10.1128/aac.12.3.429| url = http://aac.asm.org/cgi/pmidlookup?view=long&pmid=907333 }}</ref>
-==Synthesis==
-[[File:Tolciclate synthesis.png|thumb|center|400px|Tolciclate synthesis:<ref>https://www.jstage.jst.go.jp/article/bcsj1926/37/1/37_1_40/_pdf</ref><ref>Melloni, P.; Rafaela, M.; Vechietti, V.; Logemann, W.; Castellino, S.; Monti, G.; De Carneri, I.; Eur. J. Med. Chem. 1974, 9, 26.</ref>]]
 ==See also==
@@ Line 64: / Line 65: @@
 ==References==
-{{reflist}}
+{{reflist|2}}
 {{Antifungals}}
 [[Category:Antifungals]]
+[[Category:Drug]]
-{{dermatologic-drug-stub}}

v t e Antifungals (D01 and J02)
Antibiotics	Griseofulvin • polyene antimycotics (Natamycin, Nystatin)
Topical azoles	imidazoles (Bifonazole, Clomidazole, Clotrimazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole) • triazoles (Fluconazole) • benzimidazole (Thiabendazole)
Other topicals	Ciclopirox • Ethylparaben • Flucytosine • Salicylic acid • Selenium sulfide • Tolnaftate • Undecylenic acid • allylamines (Amorolfine, Butenafine, Naftifine, Terbinafine)
For systemic use	Griseofulvin • allylamine (Terbinafine) • polyene antimycotic (Amphotericin B) • triazoles (Itraconazole, Posaconazole, Voriconazole) • echinocandins (Anidulafungin, Caspofungin, Micafungin)
Other	Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle

Tolciclate: Difference between revisions

Latest revision as of 17:18, 20 August 2015

Overview

See also

References

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