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{{DISPLAYTITLE:Flutemetamol (<sup>18</sup>F)}}
[[File:Flutemetamol Info.png|right|300px]]
{{Infobox drug new
| drug_name        = Flutemetamol (<sup>18</sup>F)
| IUPAC_name        = 2-[3-(<sup>18</sup>F)Fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol
| image            = Flutemetamol wiki str.png
 
| alt              =
| caption          =
 
<!-- Clinical data -->
| tradename        = Vizamyl
| Drugs.com        = {{Drugs.com|CONS|flutemetamol-f-18-intravenous}}
| MedlinePlus      =
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = C
| pregnancy_category=
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = Rx-only
| legal_status      =
| routes_of_administration = [[Intravenous]]
 
<!-- Pharmacokinetic data -->
| bioavailability  =
| protein_bound    =
| metabolism        =
| onset            =
| elimination_half-life =
| excretion        =
 
<!-- Identifiers -->
| CAS_number        =
| ATCvet            =
| ATC_prefix        = V09
| ATC_suffix        = AX04
| PubChem          = 15950376
| DrugBank          =
| ChemSpiderID      = 13092196
| UNII              = 0F3M7032P5
| ChEBI            = 76611
 
<!-- Chemical data -->
| chemical_formula  = C<sub>14</sub>H<sub>11</sub><sup>18</sup>FN<sub>2</sub>OS
| molecular_weight  = 273.316 g/mol
| smiles  = CNC1=C(C=C(C=C1)C2=NC3=C(S2)C=C(C=C3)O)[18F]
| StdInChI=1S/C14H11FN2OS/c1-16-11-4-2-8(6-10(11)15)14-17-12-5-3-9(18)7-13(12)19-14/h2-7,16,18H,1H3/i15-1
| StdInChIKey = VVECGOCJFKTUAX-HUYCHCPVSA-N
}}
__NOTOC__
__NOTOC__
{{SI}}
{{SI}}

Latest revision as of 21:09, 18 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Flutemetamol (18F) (trade name Vizamyl, by GE Healthcare) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18, used as a diagnostic tool for Alzheimer's disease.[1]

Mechanism of action

After the substance is given intravenously, it accumulates in beta amyloid plaques in the patient's brain, which thus become visible via positron emission tomography (PET).[1]

References

  1. ↑ 1.0 1.1 H. Spreitzer (18 August 2014). "Neue Wirkstoffe – Flutemetamol". Österreichische Apothekerzeitung (in German) (17/2014): 43.

Template:Diagnostic radiopharmaceuticals

Template:Pharma-stub

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