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| <ul class="mw-collapsible" data-expandtext="Preferred regimen" data-collapsetext="Preferred regimen">
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| <li>{{abx|Cefotaxime 8–12 g/day q4–6h|Ceftriaxone 4 g/day q12h}} {{and}} {{abx|Metronidazole 30 mg/kg/day q6h}}</li>
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| </ul>
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| | | {{rx|abc}} |
| <ul class="mw-collapsible" data-expandtext="Signs and Symptoms" data-collapsetext="Signs and Symptoms">
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| <li> Fever (>38.3°C)</li>
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| <li> Hypothermia (core temperature <36°C)</li>
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| <li> Heart rate >90/min–1 or more than two SD above the normal value for age</li>
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| <li> Tachypnea</li>
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| <li> Altered mental status</li>
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| <li> Significant edema or positive fluid balance (>20 mL/kg over 24 hr)</li>
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| <li> Hypotension (SBP <90 mm Hg, MAP <70 mm Hg, or an SBP decrease >40 mm Hg)</li>
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| <li> Hypoxemia (Pao2/Fio2 <300)</li>
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| <li> Acute oliguria (urine output <0.5 mL/kg/hr for at least 2 hrs despite adequate fluid resuscitation)</li>
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| <li> Ileus (absent bowel sounds)</li>
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| <li> Diminished capillary refill or mottling</li>
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| </ul>
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