Peritonitis epidemiology and demographics: Difference between revisions
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{{Peritonitis}} | {{Peritonitis}} | ||
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==Overview== | |||
==Epidemiology and Demographics== | |||
=== Prevalence of SBP<ref name="pmid26962397">{{cite journal| author=Bunchorntavakul C, Chamroonkul N, Chavalitdhamrong D| title=Bacterial infections in cirrhosis: A critical review and practical guidance. | journal=World J Hepatol | year= 2016 | volume= 8 | issue= 6 | pages= 307-21 | pmid=26962397 | doi=10.4254/wjh.v8.i6.307 | pmc=4766259 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26962397 }} </ref> === | |||
*The prevalence of SBP in cirrhotic patients with ascites admitted to the hospital ranges from 10%-30%. | |||
*About 50% of cases are present at the time of hospitalization and 50% develop during the hospitalization. | |||
===Incidence of SBP=== | |||
====In hospitalized patients==== | |||
*Studies have demonstrated a 12% incidence of spontaneous bacterial peritonitis in patients admitted with decompensated cirrhosis. | |||
====In outpatient clinic ED setting==== | |||
*2 studies examining asymptomatic patients presenting for a therapeutic paracentesis showed a combined 2.5% incidence of spontaneous bacterial peritonitis (defined as absolute neutrophil count >250 cells/mm3) in 545 patients.<ref name="Evans2003">{{cite journal|last1=Evans|first1=L|title=Spontaneous bacterial peritonitis in asymptomatic outpatients with cirrhotic ascites|journal=Hepatology|volume=37|issue=4|year=2003|pages=897–901|issn=02709139|doi=10.1053/jhep.2003.50119}}</ref><ref name="ChinnockAfarian2008">{{cite journal|last1=Chinnock|first1=Brian|last2=Afarian|first2=Hagop|last3=Minnigan|first3=Hal|last4=Butler|first4=Jack|last5=Hendey|first5=Gregory W.|title=Physician Clinical Impression Does Not Rule Out Spontaneous Bacterial Peritonitis in Patients Undergoing Emergency Department Paracentesis|journal=Annals of Emergency Medicine|volume=52|issue=3|year=2008|pages=268–273|issn=01960644|doi=10.1016/j.annemergmed.2008.02.016}}</ref> | |||
=== Mortality rate of SBP === | |||
*The in-hospital mortality for SBP ranges from 10%-50% depending on various factors. | |||
*Mortality is 20% even in treated SBP patients | |||
*Overall one-year mortality rate after a first episode of SBP is 30%-93% regardless of its recurrence. | |||
===Age=== | |||
*The maximum incidence of SBP was in age group of 41–50 years and the mean age of presentation was 49 years.<ref name="pmid26393155">{{cite journal| author=Paul K, Kaur J, Kazal HL| title=To Study the Incidence, Predictive Factors and Clinical Outcome of Spontaneous Bacterial Peritonitis in Patients of Cirrhosis with Ascites. | journal=J Clin Diagn Res | year= 2015 | volume= 9 | issue= 7 | pages= OC09-12 | pmid=26393155 | doi=10.7860/JCDR/2015/14855.6191 | pmc=4572986 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26393155 }} </ref> | |||
===Gender=== | |||
*In patients with ascites both sexes are affected equally. Male are more commonly affected with SBP probably due to increased alcohol intake leading to cirrhosis.<ref name="pmid26393155">{{cite journal| author=Paul K, Kaur J, Kazal HL| title=To Study the Incidence, Predictive Factors and Clinical Outcome of Spontaneous Bacterial Peritonitis in Patients of Cirrhosis with Ascites. | journal=J Clin Diagn Res | year= 2015 | volume= 9 | issue= 7 | pages= OC09-12 | pmid=26393155 | doi=10.7860/JCDR/2015/14855.6191 | pmc=4572986 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26393155 }} </ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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{{WH}} | |||
Latest revision as of 19:22, 10 January 2017
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Peritonitis Main Page |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]
Overview
Epidemiology and Demographics
Prevalence of SBP[1]
- The prevalence of SBP in cirrhotic patients with ascites admitted to the hospital ranges from 10%-30%.
- About 50% of cases are present at the time of hospitalization and 50% develop during the hospitalization.
Incidence of SBP
In hospitalized patients
- Studies have demonstrated a 12% incidence of spontaneous bacterial peritonitis in patients admitted with decompensated cirrhosis.
In outpatient clinic ED setting
- 2 studies examining asymptomatic patients presenting for a therapeutic paracentesis showed a combined 2.5% incidence of spontaneous bacterial peritonitis (defined as absolute neutrophil count >250 cells/mm3) in 545 patients.[2][3]
Mortality rate of SBP
- The in-hospital mortality for SBP ranges from 10%-50% depending on various factors.
- Mortality is 20% even in treated SBP patients
- Overall one-year mortality rate after a first episode of SBP is 30%-93% regardless of its recurrence.
Age
- The maximum incidence of SBP was in age group of 41–50 years and the mean age of presentation was 49 years.[4]
Gender
- In patients with ascites both sexes are affected equally. Male are more commonly affected with SBP probably due to increased alcohol intake leading to cirrhosis.[4]
References
- ↑ Bunchorntavakul C, Chamroonkul N, Chavalitdhamrong D (2016). "Bacterial infections in cirrhosis: A critical review and practical guidance". World J Hepatol. 8 (6): 307–21. doi:10.4254/wjh.v8.i6.307. PMC 4766259. PMID 26962397.
- ↑ Evans, L (2003). "Spontaneous bacterial peritonitis in asymptomatic outpatients with cirrhotic ascites". Hepatology. 37 (4): 897–901. doi:10.1053/jhep.2003.50119. ISSN 0270-9139.
- ↑ Chinnock, Brian; Afarian, Hagop; Minnigan, Hal; Butler, Jack; Hendey, Gregory W. (2008). "Physician Clinical Impression Does Not Rule Out Spontaneous Bacterial Peritonitis in Patients Undergoing Emergency Department Paracentesis". Annals of Emergency Medicine. 52 (3): 268–273. doi:10.1016/j.annemergmed.2008.02.016. ISSN 0196-0644.
- ↑ 4.0 4.1 Paul K, Kaur J, Kazal HL (2015). "To Study the Incidence, Predictive Factors and Clinical Outcome of Spontaneous Bacterial Peritonitis in Patients of Cirrhosis with Ascites". J Clin Diagn Res. 9 (7): OC09–12. doi:10.7860/JCDR/2015/14855.6191. PMC 4572986. PMID 26393155.