Epidural abscess causes: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Bot: Removing from Primary care)
 
(13 intermediate revisions by 4 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Epidural abscess}}
{{Epidural abscess}}
{{CMG}}; {{AE}} {{JS}}
{{CMG}} {{AE}} {{JS}}; {{Ochuko}}; {{AG}}


==Overview==
==Overview==
An epidural abscess is a rare suppurative [[infection]] of the [[central nervous system]], a collection of [[pus]] localised in the [[epidural space]], lying outside the [[dura mater]].  It may occur in two different places: [[intracranial space|intracranially]] or in the [[spinal canal]]. According to the region of [[infection]], some responsible organisms will be shared by both types of [[abscess]] however, others will differ, mainly because of the risk factors involved in that particular area and the mechanisms of [[infection]]. In the case of ''intracranial epidural abscess'', the most common risk factors are [[sinusitis]] and [[neurosurgery|neurosurgical procedures]], while in the case of ''spinal epidural abscess'', the most common risk factors are [[infections]] of the surrounding tissues and [[spinal cord|spinal]] procedures.
Common causes of intracranial epidural abscess include paranasal [[sinusitis]], [[osteomyelitis]] of the skull, and extension of infection from concurrent [[otitis]] or [[mastoiditis]]. Common causes of spinal epidural abscess include spinal instrumentation, [[vascular]] access, and [[IV drug use]]. Irrespective of cause, [[epidural abscess]] is a life-threatening, but treatable, condition.


==Causes==
==Causes==
===Life Threatening Causes===
''[[Staphylococcus aureus]]'' is responsible for almost two thirds of the reported cases.<ref name="Darouiche2006">{{cite journal|last1=Darouiche|first1=Rabih O.|title=Spinal Epidural Abscess|journal=New England Journal of Medicine|volume=355|issue=19|year=2006|pages=2012–2020|issn=0028-4793|doi=10.1056/NEJMra055111}}</ref><ref name="pmid10447289">{{cite journal| author=Rigamonti D, Liem L, Sampath P, Knoller N, Namaguchi Y, Schreibman DL et al.| title=Spinal epidural abscess: contemporary trends in etiology, evaluation, and management. | journal=Surg Neurol | year= 1999 | volume= 52 | issue= 2 | pages= 189-96; discussion 197 | pmid=10447289 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10447289 }} </ref>  Due to the generalized use of [[antibiotics]]  through the years, the number of reported cases of spinal epidural abscess due to [[MRSA]] has increased exponentially, reaching up to 40% of the cases in some institutions, particularly in patients with [[spinal cord|spinal]] or vascular implanted devices.<ref name="Darouiche2006">{{cite journal|last1=Darouiche|first1=Rabih O.|title=Spinal Epidural Abscess|journal=New England Journal of Medicine|volume=355|issue=19|year=2006|pages=2012–2020|issn=0028-4793|doi=10.1056/NEJMra055111}}</ref> Other less common, but still important organisms are:<ref name="Darouiche2006">{{cite journal|last1=Darouiche|first1=Rabih O.|title=Spinal Epidural Abscess|journal=New England Journal of Medicine|volume=355|issue=19|year=2006|pages=2012–2020|issn=0028-4793|doi=10.1056/NEJMra055111}}</ref><ref name="pmid15629340">{{cite journal| author=Pereira CE, Lynch JC| title=Spinal epidural abscess: an analysis of 24 cases. | journal=Surg Neurol | year= 2005 | volume= 63 Suppl 1 | issue=  | pages= S26-9 | pmid=15629340 | doi=10.1016/j.surneu.2004.09.021 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15629340  }} </ref><ref name="pmid10433605">{{cite journal| author=Chowfin A, Potti A, Paul A, Carson P| title=Spinal epidural abscess after tattooing. | journal=Clin Infect Dis | year= 1999 | volume= 29 | issue= 1 | pages= 225-6 | pmid=10433605 | doi=10.1086/520174 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prli**''[[Staphylococcus epidermidis]]''}}</ref>
Life-threatening conditions may result in death or permanent disability within 24 hours if left untreated.  [[Epidural abscess]] is a life-threatening condition and must be treated as such irrespective of the cause.
*''[[Escherichia coli]]''
 
*''[[Pseudomonas aeruginosa]]''
===Common Causes===
*[[Anaerobic bacteria]]
*[[Mycobacteria]]
*[[Fungi]]
*[[Parasites]]


==Causes by Organ System==
==Causes by Organ System==
{|style="width:82%; height:100px" border="1"
{|style="width:82%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |No underlying causes
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |[[Endocarditis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
Line 55: Line 58:
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| [[Bloodstream infections]]
|bgcolor="Beige"| [[Bloodstream infection]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
Line 111: Line 114:
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Sexual'''
| '''Sexual'''
|bgcolor="Beige"|  
|bgcolor="Beige"| No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| [[Head injury]], [[motor vehicle accident|road traffic accidents]], [[Trauma]]
|bgcolor="Beige"| [[Head injury]], [[motor vehicle accident|road traffic accidents]], [[trauma]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
Line 126: Line 129:
|-
|-
|}
|}
===Causes in Alphabetical Order===
===Causes in Alphabetical Order===
{{columns-list|2|
{{columns-list|2|
Line 180: Line 182:
*[[Trauma]]
*[[Trauma]]
}}
}}
===Causes of Epidural Abscess Bases on Classification===
===Causes of Epidural Abscess Bases on Classification===
Although some infectious organisms might be responsible for either type of [[epidural abscess]], others are more common of one of those. Therefore, it is important to specify the most common causes of each [[epidural abscess]], in order for the physician to start proper therapy as early as possible. <ref name="Darouiche2006">{{cite journal|last1=Darouiche|first1=Rabih O.|title=Spinal Epidural Abscess|journal=New England Journal of Medicine|volume=355|issue=19|year=2006|pages=2012–2020|issn=0028-4793|doi=10.1056/NEJMra055111}}</ref><ref name="DannerHartman1987">{{cite journal|last1=Danner|first1=R. L.|last2=Hartman|first2=B. J.|title=Update of Spinal Epidural Abscess: 35 Cases and Review of the Literature|journal=Clinical Infectious Diseases|volume=9|issue=2|year=1987|pages=265–274|issn=1058-4838|doi=10.1093/clinids/9.2.265}}</ref><ref name="pmid1359657">{{cite journal| author=Nussbaum ES, Rigamonti D, Standiford H, Numaguchi Y, Wolf AL, Robinson WL| title=Spinal epidural abscess: a report of 40 cases and review. | journal=Surg Neurol | year= 1992 | volume= 38 | issue= 3 | pages= 225-31 | pmid=1359657 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1359657  }} </ref><ref name="pmid1359381">{{cite journal| author=Darouiche RO, Hamill RJ, Greenberg SB, Weathers SW, Musher DM| title=Bacterial spinal epidural abscess. Review of 43 cases and literature survey. | journal=Medicine (Baltimore) | year= 1992 | volume= 71 | issue= 6 | pages= 369-85 | pmid=1359381 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1359381  }} </ref><ref>{{Cite book  | last1 = Longo | first1 = Dan L. (Dan Louis) | title = Harrison's principles of internal medici | date = 2012 | publisher = McGraw-Hill | location = New York | isbn = 978-0-07-174889-6 | pages =  }}</ref>
Although some infectious organisms might be responsible for either type of [[epidural abscess]], others are more common of one of those.<ref name="Darouiche2006">{{cite journal|last1=Darouiche|first1=Rabih O.|title=Spinal Epidural Abscess|journal=New England Journal of Medicine|volume=355|issue=19|year=2006|pages=2012–2020|issn=0028-4793|doi=10.1056/NEJMra055111}}</ref><ref name="DannerHartman1987">{{cite journal|last1=Danner|first1=R. L.|last2=Hartman|first2=B. J.|title=Update of Spinal Epidural Abscess: 35 Cases and Review of the Literature|journal=Clinical Infectious Diseases|volume=9|issue=2|year=1987|pages=265–274|issn=1058-4838|doi=10.1093/clinids/9.2.265}}</ref><ref name="pmid1359657">{{cite journal| author=Nussbaum ES, Rigamonti D, Standiford H, Numaguchi Y, Wolf AL, Robinson WL| title=Spinal epidural abscess: a report of 40 cases and review. | journal=Surg Neurol | year= 1992 | volume= 38 | issue= 3 | pages= 225-31 | pmid=1359657 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1359657  }} </ref><ref name="pmid1359381">{{cite journal| author=Darouiche RO, Hamill RJ, Greenberg SB, Weathers SW, Musher DM| title=Bacterial spinal epidural abscess. Review of 43 cases and literature survey. | journal=Medicine (Baltimore) | year= 1992 | volume= 71 | issue= 6 | pages= 369-85 | pmid=1359381 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1359381  }} </ref><ref>{{Cite book  | last1 = Longo | first1 = Dan L. (Dan Louis) | title = Harrison's principles of internal medici | date = 2012 | publisher = McGraw-Hill | location = New York | isbn = 978-0-07-174889-6 | pages =  }}</ref><ref name="pmid7395641">{{cite journal| author=Griffiths DL| title=Tuberculosis of the spine: a review. | journal=Adv Tuberc Res | year= 1980 | volume= 20 | issue=  | pages= 92-110 | pmid=7395641 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7395641  }} </ref>
 
====Intracranial Epidural Abscess====
====Intracranial Epidural Abscess====
*If [[infection]] following [[sinusitis]] case:
*If [[infection]] following [[sinusitis]] case:
:*[[Microaerophile|Microaerophilic organisms]]
:*[[Microaerophile|Microaerophilic organisms]]
:*[[streptococci|Anaerobic streptococci]]
:*[[streptococci|Anaerobic streptococci]]
:*Other [[anaerobes]] - [[Propionibacterium]]
:*[[Propionibacterium]]
:*Other [[anaerobic]] bacteria and fungi
*If [[infection]] following [[neurosurgery]]:
*If [[infection]] following [[neurosurgery]]:
:*[[Staphylococcus aureus]]
:*''[[Staphylococcus aureus]]''
:*[[Gram-negative bacteria]]
:*[[Gram-negative bacteria]]
*[[osteomyelitis|Osteomyelitis of the skull]]
*[[osteomyelitis|Osteomyelitis of the skull]]


====Spinal Epidural Abscess====
====Spinal Epidural Abscess====
*[[Staphylococcus aureus]]
*''[[Staphylococcus aureus]]''
*[[MRSA]]
*[[MRSA]]
*[[Mycobacterium tuberculosis]] <ref name="pmid7395641">{{cite journal| author=Griffiths DL| title=Tuberculosis of the spine: a review. | journal=Adv Tuberc Res | year= 1980 | volume= 20 | issue=  | pages= 92-110 | pmid=7395641 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7395641  }} </ref>
*''[[Mycobacterium tuberculosis]]''


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
{{WS}}


[[Category:Wikinfect]]
[[Category:Infectious disease]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Neurology]]
[[Category:Neurology]]
[[Category:Primary care]]
[[Category:Crowdiagnosis]]
[[Category:Crowdiagnosis]]

Latest revision as of 21:35, 29 July 2020

Epidural abscess Microchapters

Home

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Epidural abscess from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Epidural abscess causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Epidural abscess causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Epidural abscess causes

CDC on Epidural abscess causes

Epidural abscess causes in the news

Blogs on Epidural abscess causes

Directions to Hospitals Treating Epidural abscess

Risk calculators and risk factors for Epidural abscess causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]; Ogheneochuko Ajari, MB.BS, MS [3]; Anthony Gallo, B.S. [4]

Overview

Common causes of intracranial epidural abscess include paranasal sinusitis, osteomyelitis of the skull, and extension of infection from concurrent otitis or mastoiditis. Common causes of spinal epidural abscess include spinal instrumentation, vascular access, and IV drug use. Irrespective of cause, epidural abscess is a life-threatening, but treatable, condition.

Causes

Staphylococcus aureus is responsible for almost two thirds of the reported cases.[1][2] Due to the generalized use of antibiotics through the years, the number of reported cases of spinal epidural abscess due to MRSA has increased exponentially, reaching up to 40% of the cases in some institutions, particularly in patients with spinal or vascular implanted devices.[1] Other less common, but still important organisms are:[1][3][4]

Causes by Organ System

Cardiovascular Endocarditis
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat Cholesteatoma, mastoiditis, otitis, sinusitis
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic Bloodstream infection
Iatrogenic Anesthetic procedures, back surgery, craniotomy, epidural analgesia, epidural catheter, neurosurgery, post-surgical infections, scalp venous catheter, spinal surgery
Infectious Disease Aerobic gram-negative bacilli, anaerobes, anaerobic streptococci, aspergillus, blastomycosis, bloodstream infection, bone infections, candida, coagulase-negative staphylococci, dracunculus, echinococcus, encephalitis, escherichia coli, fungi, gram-negative bacilli, gram-negative bacteria, gram-positive bacilli, HIV, mastoiditis, meningitis, microaerophilic organisms, MRSA, mycobacterium tuberculosis, osteomyelitis, otitis, parasites, peptostreptococcus, post-surgical infections, propionibacterium, pseudomonas aeruginosa, pyogenic infectious discitis, sinusitis, sporothrix, staphylococcus aureus, staphylococcus epidermidis, streptococci
Musculoskeletal/Orthopedic Bone infections, osteomyelitis, pyogenic infectious discitis
Neurologic Encephalitis, head injury, meningitis
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Mycobacterium tuberculosis
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy Immunocompromised host, Low CD4+ cell count
Sexual No underlying causes
Trauma Head injury, road traffic accidents, trauma
Urologic No underlying causes
Miscellaneous Back surgery

Causes in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
2

Causes of Epidural Abscess Bases on Classification

Although some infectious organisms might be responsible for either type of epidural abscess, others are more common of one of those.[1][5][6][7][8][9]

Intracranial Epidural Abscess

Spinal Epidural Abscess

References

  1. ↑ 1.0 1.1 1.2 1.3 Darouiche, Rabih O. (2006). "Spinal Epidural Abscess". New England Journal of Medicine. 355 (19): 2012–2020. doi:10.1056/NEJMra055111. ISSN 0028-4793.
  2. ↑ Rigamonti D, Liem L, Sampath P, Knoller N, Namaguchi Y, Schreibman DL; et al. (1999). "Spinal epidural abscess: contemporary trends in etiology, evaluation, and management". Surg Neurol. 52 (2): 189–96, discussion 197. PMID 10447289.
  3. ↑ Pereira CE, Lynch JC (2005). "Spinal epidural abscess: an analysis of 24 cases". Surg Neurol. 63 Suppl 1: S26–9. doi:10.1016/j.surneu.2004.09.021. PMID 15629340.
  4. ↑ Chowfin A, Potti A, Paul A, Carson P (1999). %5b%5bStaphylococcus epidermidis%5d%5d "Spinal epidural abscess after tattooing" Check |url= value (help). Clin Infect Dis. 29 (1): 225–6. doi:10.1086/520174. PMID 10433605.
  5. ↑ Danner, R. L.; Hartman, B. J. (1987). "Update of Spinal Epidural Abscess: 35 Cases and Review of the Literature". Clinical Infectious Diseases. 9 (2): 265–274. doi:10.1093/clinids/9.2.265. ISSN 1058-4838.
  6. ↑ Nussbaum ES, Rigamonti D, Standiford H, Numaguchi Y, Wolf AL, Robinson WL (1992). "Spinal epidural abscess: a report of 40 cases and review". Surg Neurol. 38 (3): 225–31. PMID 1359657.
  7. ↑ Darouiche RO, Hamill RJ, Greenberg SB, Weathers SW, Musher DM (1992). "Bacterial spinal epidural abscess. Review of 43 cases and literature survey". Medicine (Baltimore). 71 (6): 369–85. PMID 1359381.
  8. ↑ Longo, Dan L. (Dan Louis) (2012). Harrison's principles of internal medici. New York: McGraw-Hill. ISBN 978-0-07-174889-6.
  9. ↑ Griffiths DL (1980). "Tuberculosis of the spine: a review". Adv Tuberc Res. 20: 92–110. PMID 7395641.

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Epidural_abscess_causes&oldid=1637800"