Astrocytoma epidemiology and demographics: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
 
(52 intermediate revisions by 5 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Astrocytoma}}
{{Astrocytoma}}
{{CMG}}
{{CMG}}; {{AE}} {{Fs}}, {{Ammu}}
 
Please help WikiDoc by adding more content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
==Overview==
==Overview==
The [[incidence]] of astrocytoma is 0.23 per 100,000 and the number of new cases is 700 per year. In 2012, there were an estimated 148,818 people living with [[brain]] and other [[nervous system]] [[cancer]] in the United States. The number of deaths was 4.3 per 100,000 individuals per year based on 2008-2012 mortality records. The [[Low grade astrocytoma|low-grade]] type is often found in children or young adults, while the [[High grade astrocytoma|high-grade]] type is more prevalent in adults. [[Pilocytic astrocytoma]] is more common in men, who account for 62% of all cases. The male-to-female ratio of [[diffuse astrocytoma]] is 1.5:1 and for [[anaplastic astrocytoma]] is 1.8:1. Astrocytoma is more common in caucasian [[race]].


==Epidemiology and Demographics==
==Epidemiology and Demographics==
*People can develop astrocytomas at any age.
===Incidence===
*The low-grade type is more often found in children or young adults, while the high-grade type are more prevalent in adults.
* The incidence of astrocytoma is  0.23 per 100,000 and the number of new cases is 700 per year.<ref name="BMJ">{{cite web | title = BMJ astrocytic brain tumors
*Astrocytomas in the base of the brain are more common in young people and account for roughly 75% of neuroepithelial tumors.
| url = http://bestpractice.bmj.com/best-practice/monograph/729/basics/epidemiology.html }}</ref>
* [[Diffuse astrocytoma]] has an [[incidence]] of 0.1 per 100,000, with 1500 to 1800 new cases per year in North America.
* [[Anaplastic astrocytoma]] has an [[incidence]] of 0.49 per 100,000 per year.
* [[Glioblastoma]] has an [[incidence]] of 5 per 100,000 per year.
* [[Pilocytic astrocytoma]] accounts for 0.6 - 5.1% of all intracranial [[neoplasm]]s (1.7-7% of all glial [[tumor]]s) and are the most common primary [[brain tumor]] of childhood, accounting for 70-85% of all [[Cerebellum|cerebellar]] [[Astrocytoma|astrocytomas]].<ref name="SEER">{{cite web | title = Surveillance, Epidemiology, and End Results Program
| url = http://seer.cancer.gov/statfacts/html/brain.html }}</ref>
===Prevalence===
* In 2012, there were an estimated 148,818 people living with [[brain]] and other [[nervous system]] [[cancer]] in the United States.
 
=== Mortality rate ===
* The number of deaths was 4.3 per 100,000 individuals per year based on 2008-2012 mortality records.<ref name="pmid26705298">{{cite journal |vauthors=Ostrom QT, Gittleman H, de Blank PM, Finlay JL, Gurney JG, McKean-Cowdin R, Stearns DS, Wolff JE, Liu M, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS |title=American Brain Tumor Association Adolescent and Young Adult Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012 |journal=Neuro-oncology |volume=18 Suppl 1 |issue= |pages=i1–i50 |date=January 2016 |pmid=26705298 |pmc=4690545 |doi=10.1093/neuonc/nov297 |url=}}</ref><ref name="pmid29931168">{{cite journal |vauthors=Ostrom QT, Cote DJ, Ascha M, Kruchko C, Barnholtz-Sloan JS |title=Adult Glioma Incidence and Survival by Race or Ethnicity in the United States From 2000 to 2014 |journal=JAMA Oncol |volume=4 |issue=9 |pages=1254–1262 |date=September 2018 |pmid=29931168 |doi=10.1001/jamaoncol.2018.1789 |url=}}</ref>
 
===Age===
* People may develop astrocytoma at any age.
* The [[Low grade astrocytoma|low-grade]] type is often found in children or young adults, while the high-grade type is more prevalent in adults.
* Subependymal giant cell [[tumors]] are a well known manifestation of [[tuberous sclerosis]] (TS), affecting 5-15% of [[patient]]s with the condition. They are principally diagnosed in [[patient]]s under 20 years of age, but are occasionally found in older patients as well.<ref name="Radiopaedia">{{cite web | title = Subependymal giant cell astrocytoma [Dr Bruno Di Muzio and Dr Jeremy Jones]| url = http://radiopaedia.org/articles/subependymal-giant-cell-astrocytoma }}</ref>
* [[Anaplastic astrocytoma|Anaplastic astrocytomas]] occur in adulthood with peak [[incidence]] between 40 and 50 years of age, which is older than [[Low grade astrocytoma|low grade astrocytomas]] and younger than [[glioblastoma]].<ref>{{cite book | last = Atlas | first = Scott | title = Magnetic resonance imaging of the brain and spine | publisher = Wolters Kluwer Health/Lippincott Williams & Wilkins | location = Philadelphia | year = 2009 | isbn = 078176985X }}</ref>
* [[Pilocytic astrocytoma|Pilocytic astrocytomas]] are [[tumor]]s of young people, with 75% occurring in the first two decades of life, typically 9-10 years of age. The mean age of presentation is 17 years.<ref name="Radiopaedia">{{cite web | title = Pilocytic astrocytoma [Dr Bruno Di Muzio and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/pilocytic-astrocytoma }}</ref>
* The median age of [[diffuse astrocytoma]] at the time of the diagnosis is 35 years, with a bimodel age distribution at 6 to 12 years and 26 to 46 years.
* Diffuse low grade [[gliomas]] of the [[cerebral hemisphere]]s are typically diagnosed in young adults between 20-45 years old (mean 35 years of age).<ref>{{cite book | last = Tonn | first = FirstName | title = Neuro-oncology of CNS tumors | publisher = Springer | location = Berlin New York | year = 2006 | isbn = 3540258337 }}</ref><ref name="Radiopaedia2015">{{cite web | title = Low grade infiltrative astrocytoma radio2015 [Dr Bruno Di Muzio and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/pilocytic-astrocytoma }}</ref>
* [[Pleomorphic xanthoastrocytoma]] has a median age of 22 years at initial presentation.
* Mean age at the time of diagnosis of [[anaplastic astrocytoma]] is 40 years.
* The peak [[incidence]] of [[glioblastoma]] is at ages 65 to 74 years.
===Gender===
* [[Pilocytic astrocytoma]] is more common in men, who account for 62% of all the cases.
* The male-to-female ratio of [[diffuse astrocytoma]] is 1.5:1.
* The male-to-female ratio of [[anaplastic astrocytoma]] is 1.8:1.
===Race===
* Astrocytoma is more common in Caucasian [[race]].<ref name="pmid29931168" />


==References==
==References==
{{reflist|2}}
{{reflist|2}}


{{Nervous tissue tumors}}
[[de:Astrozytom]]
[[nl:Astrocytoom]]
[[pt:Astrocitoma]]
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
[[Category:Disease]]
[[Category:Neurology]]
[[Category:Neurology]]
[[Category:Types of cancer]]
[[Category:Pathology]]
[[Category:Neurosurgery]]
[[Category:Neurosurgery]]
[[Category:Needs overview]]
[[Category:Up-To-Date]]
[[Category:Needs content]]
[[Category:Oncology]]
[[Category:Medicine]]

Latest revision as of 18:16, 31 January 2019

Astrocytoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Astrocytoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-Ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Study

Case #1

Astrocytoma epidemiology and demographics On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Astrocytoma epidemiology and demographics

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Astrocytoma epidemiology and demographics

CDC on Astrocytoma epidemiology and demographics

Astrocytoma epidemiology and demographics in the news

Blogs on Astrocytoma epidemiology and demographics

Directions to Hospitals Treating Astrocytoma

Risk calculators and risk factors for Astrocytoma epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D., Ammu Susheela, M.D. [2]

Overview

The incidence of astrocytoma is 0.23 per 100,000 and the number of new cases is 700 per year. In 2012, there were an estimated 148,818 people living with brain and other nervous system cancer in the United States. The number of deaths was 4.3 per 100,000 individuals per year based on 2008-2012 mortality records. The low-grade type is often found in children or young adults, while the high-grade type is more prevalent in adults. Pilocytic astrocytoma is more common in men, who account for 62% of all cases. The male-to-female ratio of diffuse astrocytoma is 1.5:1 and for anaplastic astrocytoma is 1.8:1. Astrocytoma is more common in caucasian race.

Epidemiology and Demographics

Incidence

Prevalence

Mortality rate

  • The number of deaths was 4.3 per 100,000 individuals per year based on 2008-2012 mortality records.[3][4]

Age

Gender

Race

  • Astrocytoma is more common in Caucasian race.[4]

References

  1. "BMJ astrocytic brain tumors".
  2. "Surveillance, Epidemiology, and End Results Program".
  3. Ostrom QT, Gittleman H, de Blank PM, Finlay JL, Gurney JG, McKean-Cowdin R, Stearns DS, Wolff JE, Liu M, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS (January 2016). "American Brain Tumor Association Adolescent and Young Adult Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012". Neuro-oncology. 18 Suppl 1: i1–i50. doi:10.1093/neuonc/nov297. PMC 4690545. PMID 26705298.
  4. 4.0 4.1 Ostrom QT, Cote DJ, Ascha M, Kruchko C, Barnholtz-Sloan JS (September 2018). "Adult Glioma Incidence and Survival by Race or Ethnicity in the United States From 2000 to 2014". JAMA Oncol. 4 (9): 1254–1262. doi:10.1001/jamaoncol.2018.1789. PMID 29931168.
  5. 5.0 5.1 "Subependymal giant cell astrocytoma [Dr Bruno Di Muzio and Dr Jeremy Jones]".
  6. Atlas, Scott (2009). Magnetic resonance imaging of the brain and spine. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. ISBN 078176985X.
  7. Tonn, FirstName (2006). Neuro-oncology of CNS tumors. Berlin New York: Springer. ISBN 3540258337.
  8. "Low grade infiltrative astrocytoma radio2015 [Dr Bruno Di Muzio and Dr Frank Gaillard]".