Astrocytoma classification: Difference between revisions

	Astrocytoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Astrocytoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-Ray
Echocardiography and Ultrasound
CT
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Study
Case #1
Astrocytoma classification On the Web
Most recent articles
cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Astrocytoma classification All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Astrocytoma classification
CDC on Astrocytoma classification
Astrocytoma classification in the news
Blogs on Astrocytoma classification
Directions to Hospitals Treating Astrocytoma
Risk calculators and risk factors for Astrocytoma classification

VisualWikitext

Latest revision as of 14:38, 25 October 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

Astrocytoma may be classified according to its histology into 4 grades: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma and glioblastoma multiforme.

Classification

Astrocytoma may be classified according to its histology into 4 grades:^[1]^[2]

Astrocytoma

Low grade

High grade

Pilocyic astrocytoma

Diffuse astrocytoma

Anaplastic astrocytoma

Glioblastomas multiform

Fibrillary astrocytoma

Gemistocytic astrocytoma

Protoplasmic astrocytoma

Oligoastrocytoma

Primary glioblastoma multiforme

Secondary glioblastoma multiforme

Low-grade astrocytoma may be classified based on tumor spread into four subtypes including:

Low-grade astrocytoma

Localized low-grade astrocytoma

Low-grade infiltrative astrocytoma
Diffuse astrocytoma

WHO grade I / II

WHO grade II

Fibrillary astrocytoma

Gemistocytic astrocytoma

Protoplasmic astrocytoma

Oligoastrocytoma

Pilocytic astrocytoma

Pilomyxoid astrocytoma

Subependymal giant cell astrocytoma

Pleomorphic xanthoastrocytoma

WHO grade I

WHO grade II

WHO grade I

WHO grade II

References

↑ Daumas-Duport C, Scheithauer B, O'Fallon J, Kelly P (November 1988). "Grading of astrocytomas. A simple and reproducible method". Cancer. 62 (10): 2152–65. PMID 3179928.
↑ Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (June 2016). "The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary". Acta Neuropathol. 131 (6): 803–20. doi:10.1007/s00401-016-1545-1. PMID 27157931.

[pmid3179928-1] Daumas-Duport C, Scheithauer B, O'Fallon J, Kelly P (November 1988). "Grading of astrocytomas. A simple and reproducible method". Cancer. 62 (10): 2152–65. PMID 3179928.

[pmid27157931-2] Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (June 2016). "The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary". Acta Neuropathol. 131 (6): 803–20. doi:10.1007/s00401-016-1545-1. PMID 27157931.

[1]

[2]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Astrocytoma}}
-{{CMG}}
+{{CMG}}; {{AE}} {{Fs}}
 ==Overview==
-There are two broad classes of classification identified within astrocytomas, based on histology, as to whether the zones of infiltration of cancer cells are narrow or diffuse.
+Astrocytoma may be classified according to its [[histology]] into 4 grades: [[pilocytic astrocytoma]], [[diffuse astrocytoma]], [[anaplastic astrocytoma]] and [[glioblastoma multiforme]].
 ==Classification==
-Within the astrocytomas, there are two broad classes recognized in literature, those with:
-* Narrow zones of infiltration (mostly invasive tumors; e.g., pilocytic astrocytoma, subependymal giant cell astrocytoma, pleomorphic xanthoastrocytoma), that often are clearly outlined on diagnostic images
-* Diffuse zones of infiltration (e.g., low-grade astrocytoma, anaplastic astrocytoma, glioblastoma), that share various features, including the ability to arise at any location in the CNS, but with a preference for the cerebral hemispheres; they occur usually in adults; and an intrinsic tendency to progress to more advanced grades.<ref> http://emedicine.medscape.com/article/283453-overview </ref>
-===Grading===
+* Astrocytoma may be classified according to its histology into 4 grades:<ref name="pmid3179928">{{cite journal |vauthors=Daumas-Duport C, Scheithauer B, O'Fallon J, Kelly P |title=Grading of astrocytomas. A simple and reproducible method |journal=Cancer |volume=62 |issue=10 |pages=2152–65 |date=November 1988 |pmid=3179928 |doi= |url=}}</ref><ref name="pmid27157931">{{cite journal |vauthors=Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW |title=The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary |journal=Acta Neuropathol. |volume=131 |issue=6 |pages=803–20 |date=June 2016 |pmid=27157931 |doi=10.1007/s00401-016-1545-1 |url=}}</ref>
-Astrocytomas have great variation in their presentation. The [[World Health Organization]] acknowledges the following grading system for astrocytomas:
-* '''Grade 1''' — [[pilocytic astrocytoma]] - primarily pediatric tumor, with median age at diagnosis of 12
+{{Family tree/start}}
-* '''Grade 2''' — diffuse astrocytoma
+{{Family tree| | | | | | | | | | | | A01 | | | | | | | | | | | | |A01=Astrocytoma}}
-* '''Grade 3''' — anaplastic (malignant) astrocytoma
+{{Family tree| | | | | |,|-|-|-|-|-|-|^|-|-|-|-|-|.| | | | | | | | | | | | }}
-* '''Grade 4''' — [[glioblastoma multiforme]] (most common)
+{{Family tree| | | | | D01 | | | | | | | | | | | D02 | | | | | | | | | | |D01=Low grade|D02=High grade}}
+{{Family tree| | | |,|-|^|-|.| | | | | | | | |,|-|^|-|.| | | | | | | | | | | | }}
+{{Family tree| | | B01 | | B02 | | | | | | | B03 | | B04 | | | | | | | | | | |B01=Pilocyic astrocytoma|B02=Diffuse astrocytoma|B03=Anaplastic astrocytoma|B04=Glioblastomas multiform}}
+{{Family tree| |,|-|-|-|v|-|^|-|v|-|-|-|.| | | |,|-|-|^|-|-|.| | | | }}
+{{Family tree| C01 | | C02 | | C03 | | C04 | | | C05 | | | | C06 | | |C01=[[Fibrillary astrocytoma]]|C02=[[Gemistocytic astrocytoma]]|C03=[[Protoplasmic astrocytoma]]|C04=[[Oligoastrocytoma]]|C05=Primary glioblastoma multiforme|C06=Secondary glioblastoma multiforme}}
+{{Family tree/end}}
-In addition to these four tumor grades, astrocytomas may combine with oligodendrocytes to produce [[oligoastrocytoma]]. Unique astrocytoma variants have also been known to exist.
+<br />
-==See Also==
+* Low-grade astrocytoma may be classified based on tumor spread into four subtypes including:
-{{main|pilocytic astrocytoma|glioblastoma multiforme}}
+{{familytree/start |summary=Low grade astrocytoma}}
+{{familytree | | | | | | | | | | | | | A01| | | | | | | | | | | | | |A01=Low-grade astrocytoma}}
+{{familytree | | | | | | | |,|-|-|-|-|-|^|-|-|-|-|-|.| | | | | | | |}}
+{{familytree | | | | | | | B01 | | | | | | | | | | B02 | | | | | | | | |B01=[[Localized low-grade astrocytoma]]|B02=Low-grade infiltrative astrocytoma<br>Diffuse astrocytoma}}
+{{familytree | | | | | | | F01 | | | | | | | | | | F02 | | | | | | | | |F01=WHO grade I / II|F02=WHO grade II}}
+{{familytree | | | | | | | |!| | |,|-|-|-|v|-|-|-|v|^|-|.| | | | | | | |}}
+{{familytree | | | | | | | |!| | C01 | | C02 | | C03 | | C04 | | | | | |C01=[[Fibrillary astrocytoma]]|C02=[[Gemistocytic astrocytoma]]|C03=[[Protoplasmic astrocytoma]]|C04=[[Oligoastrocytoma]]}}
+{{familytree | |,|-|-|-|v|-|^|-|v|-|-|-|.| | | | | | | | | | | | | | |}}
+{{familytree | D01 | | D02 | | D03 | | D04 | | | | | | | | | | | | | | |D01=[[Pilocytic astrocytoma]]|D02=Pilomyxoid astrocytoma|D03=[[Subependymal giant cell astrocytoma]]|D04=[[Pleomorphic xanthoastrocytoma]]}}
+{{familytree | E01 | | E02 | | E03 | | E04 | | | | | | | | | | | | | |E01=WHO grade I|E02=WHO grade II|E03=WHO grade I|E04=WHO grade II}}
+{{familytree/end}}
 ==References==
 {{reflist|2}}
-{{WH}}
-{{WS}}
 [[Category:Disease]]
@@ Line 35: / Line 46: @@
 [[Category:Pathology]]
 [[Category:Neurosurgery]]
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]

Astrocytoma classification: Difference between revisions

Latest revision as of 14:38, 25 October 2019

Overview

Classification

References

Navigation menu